Clinical trials: DEGLUTİTİON
GERD, Gastroesophageal Reflux
Effect of Antireflux Therapy on the Expression of Genes in Patients With GERD
Although the symptomatic and epithelial (histologic and endoscopic) response to antireflux therapy are well known and extensively studied, little is known of the genetic events occurring in response to proton pump inhibitor…
- Trial name
- NCT00624546
- Testing
- Prevacid Solutabs, Antireflux surgery
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Rochester
Achalasia Cardia
POEM Versus Pneumatic Dilatation in Achalasia Cardia
The aim of this study is to compare efficacy of POEM and pneumatic dilatation in treatment of achalasia cardia.
- Trial name
- NCT02025790
- Testing
- Per Oral Endoscopic Myotomy (POEM), Pneumatic Dilatation
- Where
- India
- Volunteers
- 140 people
- Sponsor
- Asian Institute of Gastroenterology, India
Gastroesophageal Reflux
An Assessment of pH Testing Methods
Gastroesophageal reflux disease (GERD) is a common and potentially debilitating disorder. Typical symptoms include heartburn and regurgitation of acid tasting substances.
- Trial name
- NCT01364610
- Testing
- Bravo, Standard Care
- Where
- 2 sites in Canada
- Volunteers
- 86 people
- Sponsor
- University of Calgary
Gastro Esophageal Reflux, Obesity (Disorder)
Association Between Obesity and Gastroesophageal Reflux Disease
Gastroesophageal reflux disease (GERD) is a chronic disorder marked by heartburn and regurgitation, resulting from the reflux of gastric acid or bile into the esophagus.
- Trial name
- NCT07199582
- Volunteers
- 200 people
- Sponsor
- Assiut University
Laryngomalacia
Laryngomalacia Study
Noisy breathing is commonly caused by a floppy voicebox which is a condition called laryngomalacia. The cause of laryngomalacia is not fully understood, but some studies have suggested that it could be due to acid escaping from…
- Trial name
- NCT01782560
- Testing
- Omeprazole
- Where
- Canada
- Sponsor
- Children's & Women's Health Centre of British Columbia
Gastroesophageal Reflux, Nervous System Diseases
Comparative Anti-Reflux Procedures in Neurologically Impaired Children
This trial is a randomized controlled trial of two standard anti-reflux procedures, Nissen fundoplication versus gastrojejunal feeding tubes (GJ tubes), in children and adolescents with functional and intellectual impairment who…
- Conditions
- Gastroesophageal Reflux, Nervous System Diseases, Fundoplication, Enteral Nutrition
- Trial name
- CARPNIC (NCT01307982)
- Testing
- Fundoplication, Gastrojejunal (GJ) feeding tube
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Utah
Dysphagia, Spastic Cerebral Palsy (sCP)
The Effects of Oral Facial Facilitation and Oral Motor Therapy in Dysphagia
The objective of this research is to investigate the impact of oral facial facilitation and oral motor therapy dysphagia in individuals with spastic cerebral palsy.
- Trial name
- NCT06785220
- Testing
- ORAL FACIAL FACILITATION, ORAL MOTOR THERAPY, ORAL FACIAL FACILITATION WITH ORAL MOROR THERAY
- Volunteers
- 13 people
- Sponsor
- Kafrelsheikh University
Gastroesophageal Reflux Disease (GERD)
Phase 3/Safety & Efficacy of Esomeprazole in Infants
The purpose of this study is to look at the improvement of a once a day dose of esomeprazole for reducing the signs and symptoms of infants with gastroesophageal reflux disease (GERD).
- Trial name
- NCT00468559
- Testing
- Open Label Run In Esomeprazole, Double Blind Esomeprazole
- Where
- 25 sites in United States, France and 2 more
- Volunteers
- 98 people
- Sponsor
- AstraZeneca
Cerebrovascular Accident, Deglutition Disorders
Toronto Bedside Swallowing Screening Test (TOR-BSST) - A Bedside Swallowing Screening for Stroke Patients
This research will assess the accuracy of the Toronto Bedside Swallowing Screening Test (TOR-BSST), a new dysphagia screening test for patients with stroke.
- Trial name
- NCT00141752
- Testing
- Toronto Bedside Swallowing Screening Test (TOR-BSST)
- Where
- 5 sites in Canada
- Volunteers
- 311 people
- Sponsor
- University Health Network, Toronto
Dysphagia, Oropharyngeal Dysphagia
Incidence of Dysphagia in Intensive Care Patients With Tracheostomy
This study will inform the feasibility of the High Resolution Impedance Manometry (HRIM) system combined with Automated Impedance Manometry (AIM) analysis as a screening tool for dysphagia and aspiration for the intensive care…
- Trial name
- NCT02874352
- Testing
- high resolution impedance manometry with Automated Impedance Manometry analysis
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
GERD
Structured Treatment of Gastroesophageal Reflux in a Company Health Care Setting, -Effect on Quality of Life, Symptoms and Productivity
The study aims to evaluate if a GERD treatment programme, in accordance with current regional recommendations, in a company health care setting, has an impact on health related quality of life (HRQoL), symptoms, and productivity…
- Trial name
- NCT00884247
- Where
- Sweden
- Volunteers
- 36 people
- Sponsor
- AstraZeneca
ALS, Cough
Assessment of Voluntary and Reflex Cough in Patients With ALS
This study aims to assess the presence and the intensity of voluntary and cough reflex in patients with amyotrophic lateral sclerosis (ALS), comparing the results with the healthy control group.
- Trial name
- NCT02495571
- Testing
- Cough Assessment in ALS Patients
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
GERD
Electronic Health Record (EHR)-Based Intervention for Gastroesophageal Reflux Disease (GERD) and Chronic Non-steroidal Anti-inflammatory Drug (NSAID) Use
The purpose of the study is to examine the impact of augmented, high-quality physician-coordinated care executed via an electronic health record (EHR)-based intervention on quality of care for gastroesophageal reflux disease…
- Trial name
- NCT00691171
- Volunteers
- 5,234 people
- Sponsor
- AstraZeneca
Deglutition Disorders
Comparing FEES to VFSS in Diagnosing Laryngeal Penetration and Aspiration in Infants in the NICU
The main purpose of the study is to determine whether the Fiberoptic Endoscopic Evaluation of Swallowing (FEES) is effective in detecting laryngeal penetration and tracheal aspiration when compared with the Videofluoroscopic…
- Trial name
- NCT02003287
- Testing
- VFSS, FEES
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Baylor Research Institute
The Aim of This Study is to Investigate the Frequency and Related Risk Factors of Recurrence, and Quality of Life in Patients With GERD After Treatment With PPI
Recurrence Rate, Risk Factors for the Recurrence, and Quality of Life in Patients With GERD in Korea-an Observational
Recurrence rate, risk factors for the recurrence, and quality of life in patients with GERD in Korea-an observational study.
- Trial name
- Refresh (NCT01378338)
- Where
- 10 sites in South Korea
- Volunteers
- 855 people
- Sponsor
- AstraZeneca
Cerebral Palsy, GERD
Placebo Controlled Study of Baclofen for GERD in Children With Cerebral Palsy
Despite the use of proton pump inhibitors and available prokinetics, medical therapy is ineffective in an important number of children with cerbreal palsy (CP) and gastroesophageal reflux disease (GERD), and failure of medical…
- Trial name
- NCT01386255
- Testing
- Baclofen
- Where
- United States
- Sponsor
- Boston Children's Hospital
Gastric Ulcer, Duodenal Ulcer, Anastomotic Ulcer, Reflux Oesophagitis,"Non-erosive Reflux Disease, Zollinger-Ellison Syndrome
Nexium Capsules Clinical Experience Investigation
The purpose of this study is to confirm the safety profile / factors which impact safety and efficacy of Nexium capsules in daily clinical usage for the patients who have been prescribed Nexium for "gastric ulcer", "duodenal…
- Trial name
- NCT01434485
- Where
- 47 sites in Japan
- Volunteers
- 3,691 people
- Sponsor
- AstraZeneca
Gastro-esophageal Reflux
Safety Study of Airway Clearance Techniques in Infants.
The purpose of this study is to determine whether three airway clearance techniques ( Bouncing, Assisted Autogenic Drainage ( AAD) and bouncing and AAD) provoke or aggravate gastro-esophageal reflux in infants under the age of 1…
- Trial name
- NCT02128867
- Testing
- Assisted Autogenic Drainage (AAD), bouncing and AAD, bouncing
- Where
- Belgium
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
GERD (Gastroesophageal Reflux Disease)
A Blinded Randomized Clinical Study of RefluxStop™ Compared With Nissen Fundoplication in the Treatment of GERD
This study will evaluate if the RefluxStop™ device will treat your acid reflux and improve your symptoms and how it compares to the standard surgical treatment for GERD, the Nissen fundoplication.
- Trial name
- RENEW RCT (NCT07004400)
- Testing
- RefluxStop™ implantation, Nissen fundoplication
- Where
- 4 sites in Austria, Germany and 1 more
- Volunteers
- 200 people
- Sponsor
- Implantica CE Reflux Ltd.
Head and Neck Cancer, Surgery
Impact of Nutrition and Swallowing Function of Head and Neck Cancer Patients During the Course of Treatment
Weight loss resulting from poor food intake is common in head and neck cancer patients. Currently, feeding tubes are placed before starting treatment to provide nutrition and prevent weight loss.
- Conditions
- Head and Neck Cancer, Surgery, Nutrition, Swallowing
- Trial name
- NCT01184027
- Testing
- nutrition /swallowing counseling, G-tube/swallowing intervention, nutrition /swallowing intervention
- Where
- Canada
- Sponsor
- University of Alberta
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