Clinical trials: DM
Diabetes Mellitus, Type 1, Child
The Effect of Mobile Application on the Pediatric Diabetes Management
Type 1 DM; It is a chronic metabolic disease that develops as a result of the destruction of pancreatic ß cells, which are responsible for insulin production.
- Conditions
- Diabetes Mellitus, Type 1, Child, Adolescent
- Trial name
- DM (NCT05333185)
- Testing
- DİABOT (mobile application robot )
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Dokuz Eylul University
Diabetes, Pre Diabetes
Jockey Club Precision Prevention Programme on Young Onset Diabetes
This is a community-based implementation program consisting of multiple components delivered by a multidisciplinary team to detect and prevent young onset diabetes with precision and value using biogenetic markers, digital tools…
- Conditions
- Diabetes, Pre Diabetes, Hypertension, Dyslipidemia
- Trial name
- NCT06693934
- Testing
- Risk assessment with biogenetic and clinical test to predict diabetes risk, Oral glucose tolerance test (OGTT) and cardiovascular-kidney-metabolic (CKM) risk factors, Medication
- Where
- Hong Kong
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Juliana CN Chan
Myositis
Investigating Genes in Patients With Polymyositis and Dermatomyositis
Polymyositis (PM), dermatomyositis (DM) and inclusion body myositis (IBM)belong to a group of inflammatory muscle disorders, of unknown cause, that are characterised by skeletal muscle inflammation and progressive muscular…
- Trial name
- UKMYONET (NCT01171573)
- Testing
- Venepuncture
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Northern Care Alliance NHS Foundation Trust
Periodontitis Stage III, Periodontitis Stage IV
Blood Glucose Screening in Patients With Advanced Periodontits: the Role of Specialist Periodontal Care in Identifying Hyperglycaemia and Supporting Patient Centered Treatment
Periodontitis is a chronic inflammatory disease and individuals with advanced periodontitis have an increased risk of hyperglycaemia.
- Conditions
- Periodontitis Stage III, Periodontitis Stage IV, Diabetes (DM), Prediabetes
- Trial name
- NCT07426224
- Testing
- Selective screening of blood glucose/HbA1c
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Folktandvården Stockholms län AB
Primary Brain Tumors, Metastatic Malignant Neoplasm to Brain
Study of 4-Demethyl-4-cholesteryloxycarbonylpenclome (DM-CHOC-PEN) in Patients With Brain Tumors
DM-CHOC-PEN is a polychlorinated pyridine cholesteryl carbonate that has demonstrated antineoplastic activities in patients with advanced cancers - melanoma, lung, breast and glioblastoma multiforme (GBM) involving the CNS during…
- Trial name
- DM-CHOC-PEN (NCT02038218)
- Testing
- 4-Demethyl-4-cholestryloxycarbonylpenclomedine
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- DEKK-TEC, Inc.
Elderly Patients (>65 Years), Diabetes (DM)
Multidisciplinary Dissection of Renal and Metabolic Effects of Glyfozines on Elderly Patients: From Molecular Aspects to Clinical Indications
The project aims to study the impact of SGLT2i therapy on clinical and biochemical aspects. in elderly. The project will combine different types of data, such as clinical and biological information, and will use advanced Bayesian…
- Conditions
- Elderly Patients (>65 Years), Diabetes (DM), Heart Disease, Renal Diseases
- Trial name
- NCT07119424
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Chiara Lanzani
Diabetes Mellitus Type II
20 Week Bridging Study in Type II DM
A multicenter, non-comparative, one arm, open, phase III study to evaluate the efficacy and safety of insulin glargine on subjects with Type 2 Diabetes Mellitus
- Trial name
- NCT00563225
- Testing
- Insulin Glargine
- Volunteers
- 90 people
- Sponsor
- Sanofi
Type 2 Diabetes Mellitus
Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (LixiLan) to Lixisenatide on Top of Oral Anti-diabetic Drugs (OADs) With Type 2 Diabetes in Japan
Primary Objective: To compare LixiLan to lixisenatide in glycated hemoglobin (HbA1c) change from baseline to Week 26 in patients with type 2 diabetes mellitus.
- Trial name
- LIXILAN JP-O1 (NCT02749890)
- Testing
- Insulin glargine/Lixisenatide (HOE901/AVE0010), Lixisenatide (AVE0010), Oral anti-diabetic drugs
- Where
- 61 sites in Japan
- Volunteers
- 321 people
- Sponsor
- Sanofi
Type 2 Diabetes Mellitus (DM)
Mulligan Mobilization With Movement Versus Conventional Physiotherapy on Ankle Range of Motion, Mobility, Pain, and Quality of Life in Patients With Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus (T2DM) is a major global health concern associated with chronic hyperglycemia, oxidative stress, and accumulation of advanced glycation end-products, which impair connective tissue function and commonly…
- Trial name
- NCT07827625
- Testing
- Experimental, Control
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Ibadat International University, Islamabad
Pancreatic Cancer
Ph 2 Trial of Vitamin C & G-FLIP (Low Doses Gemcitabine, 5FU, Leucovorin, Irinotecan, Oxaliplatin) for Pancreatic Cancer
Pancreatic cancer, especially at advanced metastatic stage, is a devastating disease. It is the fourth leading cause of cancer death. Its prognosis is grim - 5-year survival rate being 6%.
- Trial name
- NCT01905150
- Testing
- G-FLIP, G-FLIP-DM, Vitamin C
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Bruckner Oncology
Diabetes Mellitus Type 2
ENhancing Outcomes Through Goal Assessment and Generating Engagement in Diabetes Mellitus
The purpose of this study is to evaluate whether a combination of pharmacist-delivered patient engagement techniques improves disease control and medication adherence among patients with poorly-controlled diabetes compared with…
- Trial name
- ENGAGE-DM (NCT02910089)
- Testing
- Shared Decision Making
- Where
- United States
- Volunteers
- 1,400 people
- Sponsor
- AstraZeneca
Diabetic Foot Ulcer, Diabetes Mellitus (DM)
Evaluating the Efficacy of Pulsating Electromagnetic Field Therapy by CRAD ULCER X-01 for Diabetic Foot Ulcers
Background: Diabetic foot ulcer (DFU) is a frequent complication of chronic, uncontrolled diabetes mellitus (DM). Treatment with antibiotics, daily dressing, wound debridement, and wound off-loading is often prescribed.
- Trial name
- NCT07465640
- Testing
- Pulsating electromagnetic field
- Where
- Malaysia
- Volunteers
- 32 people
- Sponsor
- National Defence University of Malaysia
Breast Cancer
Prospective Chart-Review: Impact of Combination - Digital Breast Tomosynthesis + Digital Mammography
Digital Breast Tomosynthesis (DBT) is a technology that has been developed to improve lesion detection in dense breasted women. Even though DBT has been regarded as a study for dense breasted women, it may also improve lesion…
- Trial name
- NCT01593384
- Volunteers
- healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Myotonic Dystrophy
The United Kingdom National Registry for Myotonic Dystrophy
Myotonic dystrophy (dystrophia myotonica - DM) exists in two forms, usually referred to as DM1 (type 1) and DM2 (type 2). Both conditions are genetic disorders but each affects a different gene.
- Trial name
- NCT04003363
- Testing
- Patient Registry
- Where
- United Kingdom
- Volunteers
- 900 people
- Sponsor
- Newcastle University
Pre Diabetes, ASCVD
Comparison of Low-Intensity Statin Plus Ezetimibe Versus High-Intensity Statin Therapy on Risk of New-Onset Diabetes Mellitus (PROVE-DM)
This study is to evaluating the impact of low-intensity statin plus ezetimibe versus high-intensity statin therapy on risk of new-onset diabetes mellitus in patients with atherosclerotic cardiovascular disease who have…
- Trial name
- NCT05579626
- Testing
- high-intensity statin arm, low-intensity statin plus ezetimibe
- Where
- 31 sites in South Korea
- Volunteers
- 4,000 people
- Sponsor
- Seung-Whan Lee, M.D., Ph.D.
Agitation in Patients With Dementia of the Alzheimer's Type
Long Term, Extension Study of the Safety and Efficacy of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type
This was an extension study of the Phase 3 Studies 15-AVP-786-301, 15-AVP-786-302, and 17-AVP-786-305.
- Trial name
- NCT02446132
- Testing
- AVP-786
- Where
- 227 sites in United States, Bulgaria and 8 more
- Volunteers
- 1,197 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Type 2 Diabetes Mellitus
Tissue Distribution of F18-FDG Labelled Autologous Bone Marrow Derived Stem Cells in Patients With Type 2 DM
Investigators purpose is to track stem cells in vivo in the type 2 diabetes mellitus patients after the same have been labelled with positron emission tomography tracer F18-FDG; as it is assumed that the therapeutic outcome will…
- Trial name
- NCT01694173
- Testing
- Stem cell therapy- SPD artery, Stem cell therapy- splenic artery, Stem cell therapy-intravenous
- Where
- India
- Volunteers
- 28 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Diabetes Mellitus, Type 2
RF Vapor Ablation Retreatment of Duodenal Mucosa in Non-responders With Type-2 Diabetes Mellitus
The purpose of this study is to test the hypothesis that re-treatment of the duodenal mucosa with RF vapor ablation will result in improvement in glycemic parameters, without complications (bleeding/ stricture / perforation)…
- Trial name
- NCT06724822
- Testing
- RF Vapor Ablation
- Where
- Chile
- Volunteers
- 12 people
- Sponsor
- Aqua Medical, Inc.
Gestational Diabetes Mellitus in Pregnancy
Lifestyle Intervention IN Gestational Diabetes (LIVING)
Investigators have taken the learning from various programs to develop a new lifestyle program (LIVING) that has a high probability of being feasible, acceptable and cost-effective in the South Asian context for women with prior…
- Trial name
- LIVING (NCT03305939)
- Testing
- Life style Intervention
- Where
- 20 sites in Bangladesh, India and 1 more
- Volunteers
- 1,612 people, healthy volunteers welcome
- Sponsor
- The George Institute
Type 2 Diabetes Mellitus
Comparative Interventional Study to Evaluate the Role of LRYGBP, LSG & SMM
A Comparative Interventional Study to Evaluate the Role of Laparoscopic Roux-en-Y Gastric Bypass (LRYGBP), Laparoscopic Sleeve Gastrectomy (LSG) and Standard Medical Management (SMM) in Patients of Type II Diabetes Mellitus (DM)…
- Trial name
- NCT04058730
- Testing
- Laparoscopic Roux en Y Gastric by pass surgery, Laparoscopic Sleeve Surgery, Standard Medical Management
- Where
- 2 sites in India
- Volunteers
- 150 people
- Sponsor
- Max Institute of Minimally Access, Metabolic & Bariatric Surgery