Clinical trials: Damage Muscle
Oxidative Stress, Muscle Strength
The Effects of Antioxidant Supplementation on Multiple Endurance Race Performance, Physiology, and Recovery.
Thirty active male and female athletes will be recruited for the study. Subjects will be examined at baseline for VO2max performance.
- Conditions
- Oxidative Stress, Muscle Strength, Resistance Training, Body Composition
- Trial name
- NCT04314596
- Testing
- Cross Training Course, Oceanix
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Cerebral Palsy, Spasticity
Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Arm(s) or of Arm(s) and Leg(s) in Cerebral Palsy
The purpose of this study is to determine whether injections of Botulinum toxin type A into muscles of one or both arms alone or in combination with injections into one or both legs are effective and safe in treating…
- Trial name
- XARA (NCT02002884)
- Testing
- IncobotulinumtoxinA (8 Units per kg body weight), IncobotulinumtoxinA (6 Units per kg body weight), IncobotulinumtoxinA (2 Units per kg body weight)
- Where
- 32 sites in United States, Argentina and 4 more
- Volunteers
- 351 people
- Sponsor
- Merz Pharmaceuticals GmbH
Oxidative Stress, Muscle Strength
The Long-term Effects of Oceanix™ on Resistance Training Adaptations
This study will examine the effects of Oceanix™, an antioxidant supplement, on muscle performance, immune and endocrine function, recovery and safety in participants undergoing resistance training.
- Conditions
- Oxidative Stress, Muscle Strength, Resistance Training, Body Composition
- Trial name
- NCT04136821
- Testing
- Oceanix, Resistance Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Cerebral Palsy, Muscle Spasticity
Dysport® Pediatric Lower Limb Spasticity Follow-on Study
The purpose of this research study was to determine the long term safety and efficacy of repeated treatments with Dysport® used in the treatment of lower limb spasticity in children with dynamic equinus foot deformity due to…
- Conditions
- Cerebral Palsy, Muscle Spasticity, Children
- Trial name
- NCT01251380
- Testing
- Botulinum toxin type A
- Where
- 27 sites in United States, Chile and 4 more
- Volunteers
- 216 people
- Sponsor
- Ipsen
Spasticity
Study of Intramuscular Injections of OnabotulinumtoxinA to Assess Change in Disease Activity in Pediatric Participants With Spasticity Associated With Cerebral Palsy
Spasticity is often observed as muscle tightness and stiffness in the upper and/or lower limbs. Upper limb spasticity can interfere with joint movement and its severity can range from mild to severe.
- Trial name
- NCT06150729
- Where
- 8 sites in Mexico
- Volunteers
- 107 people
- Sponsor
- AbbVie
Pediatrics, Muscle Spasticity
BOTOX® Treatment in Pediatric Lower Limb Spasticity
This study will evaluate the safety and efficacy of BOTOX® (botulinum toxin Type A) in pediatric patients with lower limb spasticity.
- Conditions
- Pediatrics, Muscle Spasticity, Cerebral Palsy
- Trial name
- NCT01603628
- Testing
- botulinum toxin Type A
- Where
- 53 sites in United States, Hungary and 7 more
- Volunteers
- 384 people
- Sponsor
- Allergan
Muscle Soreness, Pain
Recovery and Muscle Function After Supplementation With Turmeric
The objective of the study is to test the capacity of a five-day supplementation of Turmipure Gold® to improve exercise-induced muscle pain and function recovery in moderately active adults after exercise-induced muscle damage
- Conditions
- Muscle Soreness, Pain, Muscle Damage
- Trial name
- RECOFAST (NCT04946981)
- Testing
- Turmipure Gold®
- Where
- Ireland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Givaudan France Naturals
Pediatrics, Muscle Spasticity
BOTOX® Open-Label Treatment in Pediatric Upper Limb Spasticity
This study will evaluate the long-term safety of BOTOX® (botulinum toxin Type A) for the treatment of pediatric upper limb spasticity.
- Conditions
- Pediatrics, Muscle Spasticity, Cerebral Palsy, Stroke
- Trial name
- NCT01603615
- Testing
- Botulinum Toxin Type A
- Where
- 48 sites in United States, Canada and 7 more
- Volunteers
- 220 people
- Sponsor
- Allergan
Musculoskeletal Inflammation, Exercise-Induced Muscle Damage
A Clinical Trial to Evaluate the Effects of Peptide Gummies on Markers of Inflammation, Physical Performance, and Recovery
This study will evaluate the effects of Parlay Recover peptide gummies (containing Body Protection Compound BPC-157) on markers of inflammation, physical performance, and recovery in physically active adults.
- Conditions
- Musculoskeletal Inflammation, Exercise-Induced Muscle Damage, Post-Exercise Recovery, Musculoskeletal Pain
- Trial name
- NCT07752381
- Testing
- Parlay Recover Peptide Gummies
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Parlay Wellness
Pea Proteins, Muscle Damage
Effects of Pea Proteins on Muscle Damage and Recovery
This study is a double-blind, randomized, placebo-controlled, crossover clinical trial of N=40 recreationally active men to be recruited a single investigational center in Ohio (i.e., The Center for Applied Health Sciences).
- Conditions
- Pea Proteins, Muscle Damage, Amino Acid Change
- Trial name
- NCT05657314
- Testing
- Active Comparator
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Center for Applied Health Sciences, LLC
Soreness, Muscle, Performance Enhancing Product Use
Acute Study on Muscle Soreness, Damage, and Performance
The acute study will evaluate pre- and post-exercise ingestion of a multi-ingredient supplement in a randomized, double-blind, placebo-controlled, crossover design.
- Conditions
- Soreness, Muscle, Performance Enhancing Product Use, Damage Muscle
- Trial name
- NCT04230226
- Testing
- Pre-workout plus and protein recovery plus
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Pharmanex
Muscle Spasticity, Hypertonia, Muscle
Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals
To assess the safety and tolerability of single and multiple doses of MTR-601 in normal healthy volunteers under fed and fasted conditions. To evaluate the plasma and urine pharmacokinetics (PK) of MTR-601.
- Conditions
- Muscle Spasticity, Hypertonia, Muscle, Cerebral Palsy, Multiple Sclerosis
- Trial name
- NCT06117020
- Testing
- MTR-601
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Motric Bio
Tendon Injuries
A Methodology Study to Assess Muscle Damage After Eccentric Exercise
An isolated bout of unaccustomed maximal eccentric exercise is associated with muscle force loss for 2-4 days, mild reversible muscle tenderness, and ultra-structural damage to the muscle fibers, elevation of muscle proteins in…
- Trial name
- NCT02014662
- Testing
- Eccentric exercise
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline