Clinical trials: Damage Muscle
Healthy Adult
Effects of Astragalus Membranaceus on Muscle Function
This study evaluated whether daily supplementation with Astragali radix extract (480 mg/day) for 10 weeks could attenuate training-induced impairments in muscle function, joint pain, and inflammatory markers in moderately active…
- Trial name
- AD ASTRA (NCT07552675)
- Testing
- Astragalus Membranaceus
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Exercise-Induced Muscle Damage, Rhabdomyolysis
DOES LOWER BODY PLYOMETRICS CAUSE RHABDOMYOLYSIS IN FEMALE VOLLEYBALL PLAYERS-AN EXPERIMENTAL STUDY
Eight-week interventional study to evaluate whether lower-body plyometric training alters serum creatine phosphokinase (CPK) and creatinine levels in female collegiate volleyball players.
- Conditions
- Exercise-Induced Muscle Damage, Rhabdomyolysis, Athletes
- Trial name
- NCT07352319
- Testing
- plyometric program
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Skeletal Muscle Damage, Muscle Damage
Whey and Soy Protein Supplementation in Football Players
In a constant effort to find ways to make a quicker recovery between demanding workouts and football matches, this study is the first to investigate the benefits of protein supplementation, and compares two types of proteins, an…
- Conditions
- Skeletal Muscle Damage, Muscle Damage, Athletic Performance
- Trial name
- NCT03753321
- Testing
- Whey protein, Soy protein
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Muscle Recovery, Oxidative Stress
Development of a Coffee Pulp Infusion as a Strategy for Recovery After Moderate Physical Exercise in a Healthy Population.
The goal of this clinical trial is to learn if a coffee pulp infusion works to improve muscle recovery after moderate physical exercise in a healthy adult population.
- Conditions
- Muscle Recovery, Oxidative Stress, Inflamation, Muscle Damage
- Trial name
- COPULP-REC (NCT07875699)
- Testing
- Two 250 mL infusions per day (one in the morning and one at night) for 45 consecutive days.
- Where
- Spain
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- David Ramiro Cortijo
Cerebral Palsy (CP)
Association Between Extremity Muscle Strength and Functional Outcomes in Children With Cerebral Palsy
The aim of this study was to evaluate whether upper and lower extremity muscle strength is a factor in activity, participation and quality of life parameters in school-age children with CP and to reveal the difference in upper…
- Trial name
- NCT07448207
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Muscle Damage, Oxidative Stress
Iron Supplementation and Eccentric Exercise
Iron supplementation is very common in athletes, probably due to its catalytic role on the oxygen transport and optimal function of oxidative enzymes and proteins during exercise.
- Trial name
- NCT02374619
- Testing
- Iron supplement Resoferon Ferrous Sulfate
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Muscle Damage, Muscle Soreness
The Effects of Restriction Pressure on Muscle Damage Responses to Blood Flow Restriction Exercise
Blood flow restriction (BFR) exercise involves the application of a constriction device to the limbs to restrict muscle blood flow during exercise.
- Conditions
- Muscle Damage, Muscle Soreness, Muscle Strength
- Trial name
- NCT05037942
- Testing
- Blood flow restriction at 40% limb occlusion pressure, Blood flow restriction at 80% limb occlusion pressure
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Becker Muscular Dystrophy, McArdle Disease
Fast Troponin as a Biomarker to Assess Exercise-induced Muscle Damage in Muscle Diseases
The purpose of the study is to explore the biomarker Fast Troponins response to exercise in patients with Becker muscular dystrophy, Limb-girdle muscular dystrophy and McArdle disease
- Conditions
- Becker Muscular Dystrophy, McArdle Disease, Limb-Girdle Muscular Dystrophy Type 2
- Trial name
- NCT04349566
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mads Peter Godtfeldt Stemmerik
Ozone Therapy, Muscle Damage
Effects of Ozone Therapy on Muscle Damage
The goal of this clinical trial is to determine the effectiveness of different ozone therapy methods in enhancing recovery after muscle-damaging exercise in healthy adults, and to evaluate their impact on biochemical markers of…
- Conditions
- Ozone Therapy, Muscle Damage, Oxidative Stress, Recovery
- Trial name
- NCT07728422
- Testing
- Autohemotherapy, Ozone Sauna Therapy, Ozonated Lavender Oil Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Inonu University
Muscle Damage
Effect of Strength Versus Endurance Training on Muscle Damage in Gym Athletes on Caffeine Supplementation.
Dietary supplements to enhance exercise and athletic performance come in a variety of forms, including tablets, capsules, liquids, powders, and bars.
- Trial name
- NCT06086691
- Testing
- Strength Training with Caffeine, Endurance Training with Caffeine
- Where
- Pakistan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Exercise-induced Muscle Damage, Movement Disorders
Neurodynamic Mobilization and Foam Rolling
The purpose of this study was to assess the acute effects of a single NM treatment session on DOMS and to compare them with those of one foam roller (FR) session.
- Conditions
- Exercise-induced Muscle Damage, Movement Disorders, Nerve Pain
- Trial name
- NCT03160937
- Testing
- Manual therapy
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
Exercise Recovery
Recovery With Tart Cherry Supplementation Following a Marathon.
The goal of this clinical trial is to compare recovery in healthy, active runners. The main questions it aimed to answer were whether 7 day supplementation with Vistula TC attenuated: muscle function inflammation soreness…
- Trial name
- NCT06332222
- Testing
- Tart Cherry
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Muscle Damage
Sex Differences in Muscle Damage Following Resistance Exercise at Low or High Intensity
Purpose: To investigate the impact of exercise load on resistance exercise-induced muscle damage in untrained males and females.
- Trial name
- EIMD-LOAD (NCT05111054)
- Testing
- Resistance Exercise
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Durham University
Delayed Onset Muscle Soreness, Exercise-Induced Muscle Damage
Mineral-Infused Clothing for Recovery From Muscle Soreness and Muscle Damage After Exercise
The goal of this clinical trial is to learn whether wearing mineral-infused clothing helps muscles recover after a hard bout of unaccustomed exercise in healthy adults aged 18 to 45 who have not done lower-body resistance or jump…
- Trial name
- PERFICT (NCT07873866)
- Testing
- Mineral-infused garment, Non-infused control garment, Muscle-damaging eccentric exercise (drop jumps)
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- StudySetGo
Photobiomodulation, Fatigue
Photobiomodulation Effects on Fatigue and Muscle Damage Induced by NMES
Neuromuscular electrical stimulation (NMES) is widely used to improve muscle strength and mitigate atrophy. However, its clinical efficacy is often limited by early neuromuscular fatigue, muscle damage, and discomfort, which…
- Conditions
- Photobiomodulation, Fatigue, Discomfort, Electrical Stimulation
- Trial name
- NCT07602933
- Testing
- Active Photobiomodulation, NMES-evoked fatigue protocol
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Muscle Damage
Water Oxygenation and Brain Activity
The primary purpose of this interventional, placebo controlled, crossover, double blind, basic science exploratory study is to investigate whether there is a difference in brain electrophysiological oscillatory activity in…
- Trial name
- NCT02688452
- Testing
- Electrokinetically modified water (EMW)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Tendon Injuries
GSK1278863 Effects on Eccentric Exercise-Induced Muscle Damage
As per non-clinical studies, prolyl hydroxylase inhibitor GSK1278863 can protect muscle from unaccustomed exercise induced muscle damage and enhance functional muscle repair.
- Trial name
- NCT02231190
- Testing
- GSK1278863
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Exercise Training, Microgreens
Microgreens and miRNAs
In this study, we investigated the impact of a comprehensive microgreen and wheatgrass juice protocol on the miRNA response following a standardized EIMD model and whether microgreen consumption could modulate key miRNA markers…
- Conditions
- Exercise Training, Microgreens, miRNAs
- Trial name
- GreenmiRNAs (NCT07540858)
- Testing
- Microgreens, not received any supplement
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Spastic Cerebral Palsy (sCP)
Botulinum Neurotoxin for Children With CP: a Delicate Balance Between Clinical Benefits and Muscular Harm
A cross-sectional design study will be carried out to explore the morphological muscle properties and alterations in muscle composition on a macroscopic level in children with spastic cerebral palsy (CP).
- Trial name
- Bo-Balance (NCT06991725)
- Where
- Belgium
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Muscle Damage, Muscle Inflammation
The Effects of High Dose Fish Oil Supplementation on Delayed Onset Muscle Soreness and Inflammatory Markers
The purpose of this study is to determine the effects of fish oil supplementation (Lovaza, GlaxoSmithKline) on muscle strength, muscle soreness and inflammation following exercise.
- Trial name
- NCT00805870
- Testing
- Lovaza (omega-3-acid ethyl esters), Wheat Germ Oil
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Western Michigan University