Clinical trials: Degenerative Joint Disease
Osteoarthritis, Knee
Somatosensory Stimulation in Knee Osteoarthritis
Worldwide, 9.6% of men and 18% of women aged over 60 years suffer from osteoarthritis (OA), most of which involve the knee. Within the OA patient population, 80% of the OA patients have limitations of movement, and 25% cannot…
- Trial name
- NCT02854176
- Testing
- Somatosensory electrical stimulation, Control
- Volunteers
- 20 people
- Sponsor
- Menno Veldman
Osteoarthritis, Hip
Variability in Spinopelvic Parameters Among Patients Undergoing Total Hip Arthroplasty
This research is being conducted to assess measurement correlations on different X-ray views on patients who have undergone or will undergo hip reconstruction surgery.
- Trial name
- NCT05212090
- Testing
- EOS X-Ray
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Knee Osteoarthritis
The McKenzie System With Arthritic Knees: Do Some Knees Respond to Specific Exercise More Than General or no Exercise
The purpose of the study is to explore if a subgroup of people with osteoarthritic knees can be identified using the McKenzie System of Mechanical Diagnosis and Therapy.
- Trial name
- NCT01641874
- Testing
- Exercise, Evidence based exercise
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Knee Osteoarthritis (Knee OA)
Evaluation of a Preoperative Education in Total Knee Arthroplasty
The benefit of preoperative rehabilitation treatment combining physiotherapy and targeted education for patient undergoing Total Knee replacement (TKR) is now well known.
- Trial name
- EPOP (NCT01747759)
- Testing
- Kruskal-Wallis and qualitative parameters
- Where
- France
- Volunteers
- 44 people
- Sponsor
- University Hospital, Clermont-Ferrand
Osteoarthritis, Osteoarthritis, Knee
A Safety and Tolerability Study of JNJ-42160443 in Patients With Moderate to Severe, Chronic Knee Pain From Osteoarthritis
The purpose of this study is to evaluate pain relief, safety, and tolerability of a new treatment (JNJ-42160443) for moderate to severe pain of osteoarthritis of the knee in comparison to a standard pain treatment and placebo.
- Conditions
- Osteoarthritis, Osteoarthritis, Knee, Pain, Arthralgia
- Trial name
- NCT01094262
- Testing
- Oxycodone CR (standard pain medication), JNJ-42160443
- Where
- 44 sites in United States, Canada
- Volunteers
- 196 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Knee Osteoarthritis
Adductor Canal Versus Femoral Nerve Block for Analgesia Post Total Knee Arthroscopy
Total knee arthroplasty or replacement (TKA) is a surgery performed for osteoarthritis of the knee which is increasingly performed as the population ages.
- Trial name
- NCT02033603
- Testing
- Ropivacaine
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Changi General Hospital
Osteoarthritis of the Knee, Avascular Necrosis of the Femoral Condyle
Multicentre GMK UNI Anatomical Cementless Study - FR
Unicompartmental Knee Arthroplasty (UKA) is the principal surgical alternative to Total Knee Arthroplasty (TKA) in patients with end-stage unicompartmental tibiofemoral osteoarthritis (OA) of the knee.
- Conditions
- Osteoarthritis of the Knee, Avascular Necrosis of the Femoral Condyle, Revision Surgery
- Trial name
- NCT06715917
- Where
- 5 sites in France, Switzerland
- Volunteers
- 249 people
- Sponsor
- Medacta International SA
Primary Osteoarthritis of Knee Nos
All Ligaments Left In Knee Arthroplasty Trial
Compare the clinical and patient reported outcomes of the Vanguard XP Knee System to the Vanguard CR Knee System in patients with antero-medial osteoarthritis of the knee with an intact anterior cruciate ligament.
- Trial name
- ALLIKAT (NCT03302013)
- Testing
- Vanguard XP Bi-cruciate Retaining Knee Replacement System, Vanguard CR Single Cruciate Retaining Knee System
- Where
- 4 sites in United Kingdom
- Volunteers
- 260 people
- Sponsor
- University of Oxford
Knee Osteoarthritis
Benefits of Spa Therapy in Saint-Lary Soulan for Knee Osteoarthritis
The hypothesis is that the use of spa therapy in Saint-Lary Soulan for knee osteoarthritis treatment would have a therapeutic effect on this pathology.
- Trial name
- LARYTHERM (NCT05790824)
- Testing
- Spa therapy
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University of Bordeaux
Osteoarthritis, Knee
Radiofrequency Ablation on Pain Relief of Knee Osteoarthritis
Introduction Osteoarthritis (OA) is a chronic, progressive disease with high disability and teratogenicity in the joints. Deterioration of the articular cartilage is the main problem associated with osteoarthritis, which…
- Trial name
- NCT05050396
- Testing
- Cooled versus thermocoagulant Radiofrequency Ablation in pain relief of knee osteoarthritis
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ankle Osteoarthritis
Injections of SVF in Ankle Osteoarthritis
The aim of this pilot study is to analyze the effect of SVF injection produced by adipose tissue processing, in terms of clinical improvement, in patients with moderate to severe (stage 1-3) ankle osteoarthritis.
- Trial name
- NCT04998162
- Testing
- SVF injection
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoarthritis, Knee
The Effect on Knee Joint Loads of Analgesic Use Compared With Exercise in Patients With Knee Osteoarthritis - An RCT
The purpose of this study is to compare the effects of neuromuscular exercise and analgesic use on knee joint load, in patients with mild to moderate knee osteoarthritis (OA).
- Trial name
- EXERPHARMA (NCT01638962)
- Testing
- Instruction on analgesic use for pain relief (acetaminophen and NSAIDs), Neuromuscular exercise
- Where
- Denmark
- Volunteers
- 93 people
- Sponsor
- University of Southern Denmark
Knee Osteoarthritis; Insomnia; Cervical Spondylosis; Chronic Low Back Pain; Allergic Rhinitis
Validating Blinding Maintenance of a Sham-Sensitization Control Design for Sensitization Acupuncture Trials
This study is the clinical validation component of a broader research program developing a randomized controlled trial (RCT) comparing sensitization acupuncture (an individualized technique in which treatment points are selected…
- Trial name
- NCT07868224
- Testing
- Sensitization Acupuncture, Traditional Acupuncture
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Osteoarthritis
COVID-19 in Osteoarthritis Patients
While the coronavirus pandemic has spread rapidly around the world, it has generated a considerable degree of fear, concern and anxiety among the population in general and among certain groups in particular, such as older…
- Trial name
- NCT04791462
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Montpellier
Knee Osteoarthritis
Clinical Evaluation of Leech Therapy in the Treatment of Knee Osteoarthritis
This study has been designed to conduct as Randomized comparative clinical study.
- Trial name
- Leech Therapy (NCT02612974)
- Testing
- Hirudinaria granulosa, qurse mafasil
- Volunteers
- 60 people
- Sponsor
- Hamdard University
Pain, Postoperative, Shoulder Osteoarthritis
Effective Pain Management During Shoulder Replacement Surgery With EXPAREL
The purpose of this study is to examine the effectiveness of post-operative pain control of local infiltration (LIA) of EXPAREL administration to ropivacaine administered via continuous interscalene nerve block (CINB) for…
- Trial name
- NCT03474510
- Testing
- local infiltration of liposomal bupivacaine, continuous infusion of ropivacaine interscalene nerve block
- Where
- United States
- Sponsor
- TriHealth Inc.
Osteoarthritis
Resistive Exercise for Arthritic Cartilage Health (REACH)
Female subjects over the age of 40 will be recruited and randomised into a progressive resistance training (PRT) or sham-exercise group.
- Trial name
- NCT00465660
- Testing
- Progressive resistance training
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sydney
Osteoarthritis, Knee
Bayer OA Knee Pain Pilot
The objective of this study is to investigate if MRI can be used to evaluated effect of knee artery embolization for knee osteoarthritis.
- Trial name
- NCT05349682
- Testing
- dynamic contrast enhanced MRI, geniculate artery embolization
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medical University of South Carolina
Pain, Joint
Efficacy Evaluation of Hydrolyzed Collagen Peptide on Knees, Hips, and Ankle Pain in Osteoarthritis
The aim of this study is to evaluate the effectiveness of Hydrolyzed collagen peptides on joint pain, stiffness and physical function in adults with osteoarthritis who have complaints on knee joints together with hip and ankles.
- Trial name
- NCT05369780
- Testing
- Hydrolyzed Collagen Peptide
- Volunteers
- 160 people
- Sponsor
- Sel Sanayi Urunleri Ticaret ve Pazarlama A.S.
Acupuncture, Knee Osteoarthritis
A Pilot Trial of Acupuncture for Knee Osteoarthritis With Differential Functional Status of Acupoints
The investigators plan to undertake a rigorous multicentre randomised controlled trial, comparing acupuncture on sensitized acupoints with low/non-sensitive points or no acupuncture (waiting-list), to test if acupuncture on…
- Conditions
- Acupuncture, Knee Osteoarthritis, Randomized Controlled Trial
- Trial name
- NCT03008668
- Testing
- acupuncture
- Volunteers
- 36 people
- Sponsor
- West China Hospital
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