Clinical trials: Delirium Treatment
Delirium
Prophylactic Olanzapine Versus Placebo for Prevention of Postoperative Delirium After Joint Replacement Surgery
In this study we wanted to determine if perioperative administration of olanzapine prior to knee or hip replacement surgery in high risk patients would prevent the onset of postoperative delirium.
- Trial name
- NCT00699946
- Testing
- olanzapine
- Where
- United States
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- The New England Baptist Hospital
Delirium, Postoperative Cognitive Dysfunction
Rivastigmine in the Treatment of Postoperative Delirium: a Pilot Clinical Trial
The purpose of this study is to determine whether preoperative administration of Rivastigmine prevents the incidence of postoperative delirium in patients undergoing major surgery as well as postoperative cognitive dysfunction.
- Trial name
- NCT00835159
- Testing
- Rivastigmine Patch
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Circadian Dysrhythmia, Delirium
The Circadian Rhythm of ICU Patients With Acute Myocardial Infraction and the Effect of Light Therapy
By using subjective and objective measurements, the investigators monitor the change of circadian rhythm in Intensive Care Unit (ICU) patients with acute myocardial infarction and the effect of light therapy.
- Trial name
- NCT04953767
- Testing
- Blue light therapy, White light
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Premedication
Oral Dexmedetomidine vs Midazoam For Premedication
The aim of this study was to compare the effect of 2 µg/kg of oral dexmedetomidine (DEX) and 0.5 mg/kg dormicum as premedication among children undergoing dental procedures.
- Trial name
- NCT03357718
- Testing
- Precedex, Midazolam
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Intensive Care Unit Acquired Weakness, Intensive Care Unit Delirium
Efficacy of the "Start to Move" Protocol on Functionality, Delirium and Acquired Weakness in ICU
Background: ICU hospitalization is associated with loss of strength, functionality and delirium. The "Start to Move protocol" demonstrated efficacy in improving and minimizing such effects.
- Conditions
- Intensive Care Unit Acquired Weakness, Intensive Care Unit Delirium, Intensive Care Neuropathy, Intensive Care Unit Syndrome
- Trial name
- STM (NCT05053724)
- Testing
- Star to move Protocol
- Where
- Chile
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Hospital Felix Bulnes
Delirium
The ICU DElirium in Clinical PracTice Implementation Evaluation Study Screening and Treatment
Objective: Delirium is an important and frequently occurring complication in intensive care patients. However, screening and treatment of delirium is not in accordance with current national and international guidelines.
- Trial name
- iDECePTIvE (NCT01952899)
- Where
- Netherlands
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Procedural Sedation, Emergence Delirium
Positive Imagery Therapy and the Incidence of Emergence Reactions With the Use of Ketamine
The purpose of this study is to determine if positive imagery therapy while using ketamine in procedural sedation reduces the number of emergence reactions and impacts pre and post-procedural anxiety.
- Trial name
- NCT04746079
- Testing
- Positive Imagery Therapy
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Mercy Health Ohio
Delirium, Fall Injury
Care.Coach Avatars for Improvement of Outcomes in Hospitalized Elders, Including Mitigation of Falls and Delirium: a Multi-Site Clinical Study
Through NINR project 1R44NR017842-01 which preceded the present study, the investigators enhanced the care.coach avatar platform to incorporate a robust suite of evidence-based protocols based on the Hospital Elder Life Program…
- Trial name
- AvatarHELP (NCT03832192)
- Testing
- care.coach Avatar (HELP-Protocolized)
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Victor Wang
Postoperative Pain
Postoperative Discomfort After Dental General Anesthesia
The aim of this prospective, randomised, controlled clinical trial was to compare immediate postoperative discomfort, emergence delirium and recovery time of the patients intubated using either laryngeal mask airway or…
- Trial name
- NCT03197753
- Testing
- Laryngeal mask airway, Nasotracheal intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Emergence Agitation
Dexmedetomidine and Propofol in the Treatment of Emergence Agitation
1. This clinical research aims to compare the effects of dexmedetomidine and propofol on the treatment of emergence agitation in adult patients after general anesthesia. 2.
- Trial name
- NCT04142840
- Testing
- Dexmedetomidine, Propofol
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Anesthesia, Thirst; Due to Deprivation of Water
Benefits of Drinking Clear Fluids Until Called to the Operating Room in Adult Surgical Patients
The purpose of this study is to show if - compared to standard practice - allowing adults undergoing surgical procedures under anaesthesia care to drink clear fluids up to a volume of 200 ml between 2 h prior to the operation and…
- Conditions
- Anesthesia, Thirst; Due to Deprivation of Water, Aspiration
- Trial name
- HYDRATE (NCT06253052)
- Testing
- Additional pre-OP-visit, Liberal fasting regime
- Where
- Germany
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Delirium
Computer-assisted Cognitive Stimulation Treatment for Delirium
The objectives of our study are to determine whether people with delirium in a subacute care unit improve after one week with non-pharmacological therapies based on improving sleep schedules, mobility, and cognitive stimulation…
- Trial name
- Delitract (NCT07563244)
- Testing
- Specific computer-based cognitive stimulation intervention, Usual care intervention
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Delirium Treatment, Delirium Confusional State
Management of Non-pharmacologic Delirium With the Use of a Nursing-led E-health Project: a Randonmized Controlled Trial
Application of an action protocol focused on the application of non-pharmacological interventions for managing delirium in the process of prevention, diagnosis and treatment, evaluated using an e-health intervention, with a…
- Conditions
- Delirium Treatment, Delirium Confusional State, Delirium in Old Age
- Trial name
- Delirium (NCT06809894)
- Testing
- Application of an action protocol for the management of delirium through the use of non-pharmacological interventions, Tradicional management of delirium
- Where
- Spain
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Universitat de Lleida
Premedication
Dexmedetomidine Premedication in Children
The aim of this retrospective study was to detect the effectiveness of 1µg/kg oral dexmedetomidine premedication on preoperative cooperation and emergence delirium of the the young children underwent complete dental treatment.
- Trial name
- NCT03174678
- Testing
- Dexmedetomidine, apple juice
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Cardiac Surgery
Preoperative Intervention to Reduce Delirium After Cardiac Surgery
This research is designed for experimental quantitative research and is conducted by simple random sampling. Both the control group and the experimental group provided preoperative routine nursing treatment and preoperative…
- Trial name
- NCT05143580
- Testing
- Cognitive therapy, Routine care
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Changhua Christian Hospital
Delirium
Early Diagnosis and Treatment Standardization of Delirium
1. Observe the characteristics of delirium patients, searching for early diagnostic methods or finding risk factors 2. Design a guideline for delirium, diagnosis or treatment
- Trial name
- NCT03199859
- Where
- South Korea
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Dexmedetomidine, Postoperative Delirium
Different Administration Routes of Dexmedetomidine on Postoperative Delirium
Intravenous dexmedetomidine has been reported to decrease the occurrence of postoperative delirium (POD) in elderly patients. Nevertheless, some previous studies have indicated that intratracheal dexmedetomidine and intranasal…
- Conditions
- Dexmedetomidine, Postoperative Delirium, General Anesthesia
- Trial name
- NCT05952050
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.
Delirium
The Effect of Music Therapy on Delirium
The purpose of this study is to test the effect of a twice daily, 30-minute, interdisciplinary, music therapist developed, nurse initiated, music listening intervention on acutely ill older patients as compared to patients who…
- Trial name
- NCT03980782
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Postoperative Delirium, Postoperative Pain, Acute
Postoperative Delirium and Analgesia in Elderly Patients
This study aims to evaluate the effects of different postoperative analgesic approaches on postoperative delirium in elderly patients undergoing total knee arthroplasty.
- Trial name
- NCT07849517
- Testing
- adductor canal block and biFes block including bupivacain, Periarticular infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Child, Anesthesia Morbidity
Propofol for Treatment on Emergence Agitation
This study aimed to verify the effects of propofol for treatment on emergence agitation (EA) after sevoflurane anesthesia in pediatric strabismus surgery.
- Trial name
- NCT02738814
- Testing
- propofol
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital