Clinical trials: Dentistry
Surgery
The Effects of Zn-containing Granulate on Patient Morbidity and Wound Healing After Free Gingival Graft Surgery
There is no study in the literature showing the effects of Zn on wound healing after free gingival graft (FGG) operation. The aim of this randomized clinical study was to compare the early healing results of the palatal wound…
- Trial name
- NCT05684913
- Testing
- Zn granulate stent after FGG surgery, Hemostatic agent suturing
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Epinephrine Causing Adverse Effects in Therapeutic Use
Cardiovascular Effects of Racemic Epinephrine Pellets
The primary aim of this study was to determine if topical racemic epinephrine pellets affect heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP) or mean arterial pressure (MAP) in children receiving…
- Trial name
- NCT04688346
- Testing
- HemeRX epinephrine pellets
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Washington
Peri-implant Soft Tissue Healing
Soft Tissue Response and IL-1β Levels Around CAD/CAM-Milled vs 3D-Printed PMMA Healing Abutments
This study looked at how the gums and tissues around dental implants heal when using two different types of temporary healing caps made of PMMA (a common dental material).
- Trial name
- NCT07287722
- Testing
- CAD/CAM-Milled PMMA Healing Abutment, 3D-Printed PMMA Healing Abutment
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ali Hassan Eid Toto
Dental Anxiety, Pain Management
Wand STA vs SleeperOne for Pediatric Local Anesthesia (WASO-Kids)
This randomized, single-blind, split-mouth trial compares the acceptance of two computer-controlled local anaesthetic delivery (CCLAD) systems - Wand® STA and SleeperOne⑤ - in children aged 4-9 years undergoing comparable…
- Trial name
- WASO-Kids (NCT07754851)
- Testing
- Computer-controlled local anesthetic delivery system (pressure-sensing, single-tooth anesthesia type), Computer-controlled local anesthetic delivery system (corded, pen-style electronic type)
- Where
- Greece
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Dental Caries
AI-Based Detection of Dental Caries in Children
This study aims to evaluate the effects of an artificial intelligence (AI)-based caries detection system on the diagnosis and categorization of dental caries in pediatric patients.
- Trial name
- NCT06984029
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Noura Nageh Ramadan Ahmed
Dental Caries in Children
Supportive Caries Preventive Programme in Children Undergoing Dental General Anaesthesia
Early childhood caries is a persistent problem often leading to dental treatment under general anaesthesia (GA). Thus, this study was to investigate the preventive effect of two additional intensive oral hygiene appointments…
- Trial name
- NCT05110534
- Testing
- additional oral hygiene appointments
- Where
- Germany
- Volunteers
- 406 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
COVID-19 Respiratory Infection, Covid19
COVID-19 Vaccine Hesitancy and Dental Faculty Staff Members in Egypt
Healthcare workers (HCWs) play a vital role in determining the success of vaccination programs. Patient acceptance and vaccination rely greatly on the utilization and attitude of HCWs towards the vaccine, their attitude also…
- Conditions
- COVID-19 Respiratory Infection, Covid19, Vaccine Refusal
- Trial name
- NCT05009043
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mariam Ayman Amin Sharaf
Education, Medicine
Musicians' Health Education in D-A-CH
Professional musicians are often exposed to significant physical and psychological strain. Long hours of playing, high muscle tension in the head and neck area, and performance-related stress can lead to problems such as…
- Conditions
- Education, Medicine, Dentistry, Orofacial Pain
- Trial name
- MUSED-DACH (NCT07443930)
- Where
- Germany
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Pulpal Necrosis
Single-file Pulpectomy in Primary Molars
The current study evaluates the rotational One Shape single-file system regarding clinical and radiographic outcomes in root canal treatment of infected primary molars.
- Trial name
- NCT04394702
- Testing
- One Shape Single-file rotary system, manual stainless steel K-file
- Where
- Egypt
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Minia University
Dental Caries on Smooth Surface Limited to Enamel, Tooth Demineralization
Resin Infiltration and Fluoride Varnish Lesion Arresting Efficacy on Non-cavitated Proximal Lesion
Protection of dental hard tissues is one of the most important points of cariology. For this purpose, oral hygiene training (effective brushing and motivation), non-invasive approaches such as flouride varnish applications and…
- Conditions
- Dental Caries on Smooth Surface Limited to Enamel, Tooth Demineralization, Dental Caries, Dentistry, Operative
- Trial name
- NCT05202665
- Testing
- ICON DMG Resin Infiltration (micro-invasive approach), ClinproTM White Varnish, 3M ESPE Fluoride Varnish (non-invasive approach)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Endodontically Treated Teeth, Anterior Teeth
Endocrowns in Anterior Teeth: Effect of Cementation Protocols and Restorative Materials on the Clinical Performance of the Restorations
Rehabilitation of anterior endodontically treated teeth with significant coronal damage has been problematic. Adopting endocrown design to treat teeth with this condition is still under investigation.
- Trial name
- NCT05973292
- Testing
- resin cement containing phosphate ester monomer 10-methacryloyloxydecyl dihydrogen phosphate, Non MDP containg resin cement
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Identity, Body, Palate; Deformity
A Digital Method for Measurement of Palatal Asymmetry in Twins
The aim of the study is to evaluate the digital palatal model as a possible tool of human identification.
- Trial name
- NCT05349942
- Testing
- Intraoral scanning and data acquisition
- Where
- Hungary
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Underdosing of Local Anesthetics, Initial Encounter
Formulations of Liposomal Local Anesthetics
This blinded cross-over study aim to evaluate the efficacy of liposome-encapsulated ropivacaine formulation for dental anesthesia.
- Trial name
- NCT01307969
- Testing
- Ropivacaine
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Implant Dentistry, Implant Loading
Different Drilling Techniques in Posterior Maxilla
The study aimed to evaluate clinically and radiographically the effect of Magnetic Mallet technique versus Conventional Drilling technique on early loaded implant in posterior maxilla.
- Conditions
- Implant Dentistry, Implant Loading, Osteotomy Protocols
- Trial name
- NCT07606456
- Testing
- Magnetic Mallet Technique, Conventional Drilling Technique
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries, Tooth Extraction
Treating Children With Extensive Dental Needs
The goal of this qualitative study, using Grounded Theory, is to gain deeper knowledge about dentists' experiences from treating in particular young children with an extensive treatment need (mainly due to caries).
- Conditions
- Dental Caries, Tooth Extraction, Conscious Sedation, Attitude
- Trial name
- NCT06863103
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Malmö University
Nitrous Oxide Inhalation Sedation
Comparison of the Silhouette and Porter Brown Systems Used in Inhalation Sedation
This is a randomised non-blinded controlled clinical trial, which involves the measurement of efficiency and acceptability of the Silhouette Mask system and compares it with the Porter Brown Mask system used for Inhalation…
- Trial name
- NCT04734509
- Testing
- Silhouette breathing system
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Dental Anxiety, Musical Therapy
Effects of Different 432 Hz Auditory Stimuli on Physiological Stress Responses and Patient Satisfaction in Adults With Dental Anxiety During Restorative Treatment
In this four-arm randomized controlled clinical trial, 120 adults aged 18-50 years with baseline Modified Dental Anxiety Scale scores ≥13 were allocated equally to 432 Hz-based instrumental music, water sounds, human-vocal music…
- Conditions
- Dental Anxiety, Musical Therapy, Physiological Stress
- Trial name
- RCT (NCT07903844)
- Testing
- Music Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Laser Therapy
Clinical Application of Er:YAG Dental Laser System
The study aim was to evaluate the effectiveness of Er:YAG dental laser treatment modality for cavity, sensitive teeth, abnormal frenum attachment and peri-implantitis.
- Trial name
- NCT04811144
- Testing
- Er:YAG dental laser
- Where
- Taiwan
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Child Behavior, Dental Caries
Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment
Randomised clinical trial to test the efficacy, safety and cost-effectiveness of sedatives; masked, controlled, parallel design with three arms, phase 4.
- Trial name
- NASO (NCT02447289)
- Testing
- Intranasal ketamine, Oral ketamine, Intranasal midazolam
- Where
- Brazil
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Healthy, Adolescent
GumChucks vs Interdental Brushes in Plaque Removal.
This study compared two ways of cleaning between the teeth, Gumchucks (a new handled dental flossing system) and interdental brushes, in Lebanese adolescents aged 10-15 years.
- Conditions
- Healthy, Adolescent, Dental Plaque, Gingivitis
- Trial name
- NCT07140068
- Testing
- Handled dental flossing system (GumChucks®), Interdental Brush
- Where
- Lebanon
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beirut Arab University