Clinical trials: Depression Disorder
Erectile Disfunction, Coronary Artery Disease (CAD)
"Erectile Function After PCI in MI and Non-MI Patients"
The goal of this observational study is to assess changes in patients' erectile function after percutaneous coronary intervention (PCI) using a standard IIEF (International Index of Erectile Function) questionnaire at 1, 3, and 6…
- Conditions
- Erectile Disfunction, Coronary Artery Disease (CAD), Diabete Mellitus, Anxiety
- Trial name
- ERECT-PCI (NCT07444697)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Attention-Deficit and Hyperactivity Disorder, Anxiety
Correlating Real and Virtual World Behavioral Fluctuations in Adolescence
The present study will explore a new approach to ongoing evaluation and monitoring of fluctuations in personality traits via commercial video games.
- Conditions
- Attention-Deficit and Hyperactivity Disorder, Anxiety, Disruptive Mood Dysregulation Disorder, Depression
- Trial name
- NCT02281825
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Bipolar Depression
RU-486 in the Treatment of Bipolar Depression
Bipolar disorder is a chronic and recurrent illness which involves episodes of mania and depression. It is believed that disturbance of the stress hormone system (the hypothalamic-pituitary-adrenal or HPA axis) may cause thinking…
- Trial name
- NCT00359125
- Testing
- mifepristone (RU-486)
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Anxiety Disorders, Major Depressive Disorder
Acquisition and Analysis of Relationships Between Longitudinal Emotional Signals Produced by an Artificial Intelligence Algorithm and Self-questionnaires Used in the Psychiatric Follow-up of Patients With Mood and/or Anxiety Disorders: a Real-Environment Study.
The worldwide prevalence of anxiety and depression increased massively during the pandemic, with a 25% rise in the number of patients suffering from psychological distress.
- Trial name
- EMOACQ-1 (NCT05988840)
- Testing
- Acquisition and analysis of relationships between Longitudinal Emotional Signals produced by a software and Self-questionnaires.
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Emobot
Depression, Anhedonia
Multimodal Differences in Effort-based Decision-Making in Depression
Major depressive disorder (MDD) is a serious condition that causes long-term symptoms such as feeling sad, losing interest in activities, and having thoughts of self-harm.
- Trial name
- BBQS (NCT06648460)
- Testing
- Effort-based Decision-Making Task
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Stroke Sequelae, Cognitive Impairment
Remote Bimanual Virtual Rehabilitation Post CVD
The aim of the study is to develop the BrightBrainer G (grasp), a game-based upper-extremity motor and cognitive rehabilitation system using custom virtual reality simulations.
- Conditions
- Stroke Sequelae, Cognitive Impairment, Depression
- Trial name
- NCT04713384
- Testing
- Integrative tele-rehalitation of chronic stroke survivors using custom therapeutic games
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Grigore Burdea
Inflammation, Psychosocial Functioning
Mindfulness Meditation Neuroimaging Study for Undergraduates
This study is designed to test the effectiveness of mindfulness meditation intervention classes on psychosocial health outcomes.
- Conditions
- Inflammation, Psychosocial Functioning, Depression, Anxiety
- Trial name
- NCT05304052
- Testing
- Mindfulness Meditation classes
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Respiratory Depression
Postoperative Respiratory Monitoring After Neuraxial Opioid Administration for Cesarean Delivery
Respiratory depression occurs in labor and delivery; noticeably when neuraxial opioids are given.Pathophysiological respiratory depression -failure to respond to hypercapnia or hypoxia - is challenging to measure…
- Trial name
- NCT02417038
- Testing
- Capnostream
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Stanford University
Post Traumatic Stress Disorder, Anxiety
PTSD Symptoms Among Health Workers and Public Service Providers After the COVID-19 Outbreak: A 3 Month Follow up
The aim of this study is to investigate the levels of trauma and mental symptoms (i.e., depression and anxiety) among health workers and public service providers 3 months after (T2) the strict social distancing government…
- Conditions
- Post Traumatic Stress Disorder, Anxiety, Depression
- Trial name
- NCT04442243
- Volunteers
- 889 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Postpartum Anxiety, Postpartum Depression
Postpartum Screening for Anxiety and Comorbid Conditions
The goal of this project is to facilitate the design of individualized postpartum anxiety (PPA) screening strategies in British Columbia (BC), Canada.
- Conditions
- Postpartum Anxiety, Postpartum Depression, Postpartum Disorder, Postoperative Pain
- Trial name
- PPA (NCT06242717)
- Where
- Canada
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Well-Being, Psychological, Loneliness
Physiological, Hormonal, and DNA-based Mechanisms of Psychosocial Stress and Therapeutic Effect
The goal of this trial is to learn if the Groups 4 Health (G4H) intervention is effective in supporting student well-being at the University of Helsinki.
- Trial name
- NCT07152652
- Testing
- Groups 4 health
- Where
- Finland
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Major Depressive Disorder
Sensory Synchronized Imaging and Neuromodulation
The purpose of this research study is to better understand the relationship between the type of brain stimulation used and how it changes brain activity in adult military Veterans.
- Trial name
- NCT06548113
- Testing
- TMS
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Major Depressive Disorder
Linking Affective Dynamics in Response to Daily Stress to Peripheral Vascular Function in Working Age Adults
The objective of this proposal is to determine whether heightened negative affective responsivity (NA-R) to daily stressors is related to blunted nitric oxide (NO)-mediated endothelium-dependent dilation (EDD) in working age…
- Trial name
- NCT06860724
- Testing
- NG-nitro-L-arginine methyl ester (L-NAME)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Treatment Resistant Depression
Intranasal Esketamine to Maintain the Antidepressant Response to IV Racemic Ketamine
This study aims to assess the efficacy and safety of intranasal esketamine as maintenance antidepressant therapy in patients who have demonstrated clinical improvement with off-label intravenous racemic ketamine for…
- Trial name
- NCT04856124
- Testing
- Intranasal esketamine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Psych Atlanta
Job Stress, Workplace Stress
Breath Regulation and Yogic Exercise An Online Therapy for Calm and Happiness During the COVID-19 Pandemic
This study will examine the feasibility of conducting an online Randomized Controlled Trial (RCT) in frontline hospital and long term care healthcare staff in managing COVID-19 patients in London, ON.
- Conditions
- Job Stress, Workplace Stress, Compassion Fatigue, Psychological Trauma
- Trial name
- BREATH (NCT04368676)
- Testing
- Sudarshan Kriya Yoga (SKY), Health Enhancement Program
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Depression, Anxiety
Pharmacogenomic Testing to Optimize Antidepressant Drug Therapy
A randomized controlled trial comparing pharmacogenomic guided versus standard pharmacist care to optimize antidepressant drug therapy.
- Conditions
- Depression, Anxiety, Major Depressive Disorder, Generalized Anxiety Disorder
- Trial name
- NCT03591224
- Testing
- Pharmacogenomic Testing, Pharmacist Standard of Care
- Where
- 2 sites in Canada
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- John Papastergiou Pharmacy Ltd
Depression, Depressive Disorder
Targeting Adolescent Depressive Symptoms Via Brief, Web-Based Interventions
Major depression (MD) in youth is a serious psychiatric illness with extensive morbidity and mortality. The American Academy of Pediatrics recently released practice guidelines promoting primary care (PC)-based youth MD…
- Conditions
- Depression, Depressive Disorder, Behavioral Symptoms, Mood Disorders
- Trial name
- NCT04066985
- Testing
- Growth Mindset Online Single-Session Program, Self-Kindness Online Single-Session Program, Supportive Therapy Online Single-Session Program (Control)
- Where
- United States
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Child Mind Institute
Health Behavior, Work Related Stress
HRV and Coaching Preparation Phase Study
This pilot study will evaluate possible intervention components to be included in a future stress management and health behaviour change trial and to pilot test their feasibility and acceptability in a small sample.
- Conditions
- Health Behavior, Work Related Stress, Job Stress, Anxiety Depression
- Trial name
- NCT05150574
- Testing
- Core Health Program, Daily resting HRV, Momentary HRV feedback
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Brock University
Resting Metabolic Rate, Bone Mineral Density, Low, Susceptibility to
The Health of Competitive Fitness Athletes
Fitness athletes emphasize the value of staying lean, muscular and defined, and motivates and inspires followers through social media.
- Conditions
- Resting Metabolic Rate, Bone Mineral Density, Low, Susceptibility to, Body Image, Perfectionism
- Trial name
- NCT03007459
- Testing
- Psychological health, Physiological health
- Where
- Norway
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Feasibility Studies, Acceptability
Feasibility and Acceptability of a Single Session of Imagery Rescripting in a Community Sample of Adults
Negative experiences related to eating and appearance (NEREAs), such as critical commentary from parents about food, are common. They are also associated with depression and disordered eating, predictors of early mortality.
- Conditions
- Feasibility Studies, Acceptability, Depressive Symptoms, Disordered Eating Behaviors
- Trial name
- NCT06610318
- Testing
- imagery rescripting, nutrition education
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Oregon