Clinical trials: Depression Symptoms
Quality of Life, Antidepressive Agents
Study of the Effects of Plx on Bioparametric Measurements.
The main objective is to study the effects of the intake of a nutraceutical on health indicators, focused on sleep and stress, as well as cardiovascular (blood pressure...), circulating (cortisol) and body composition parameters…
- Conditions
- Quality of Life, Antidepressive Agents, Depression, Anxiety, Sleep Initiation and Maintenance Disorders
- Trial name
- NCT05128812
- Testing
- PLX
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Suicidal Ideation, Depression
Gamified VR Sports for Elderly Suicidal Ideation
Detailed Description: This quasi-experimental study investigates the effectiveness of a gamified sports exercise intervention delivered through virtual reality (VR) to improve mental health and life expectancy in elderly…
- Conditions
- Suicidal Ideation, Depression, Mental Health Issue
- Trial name
- VR-LIFE-SI (NCT06856083)
- Testing
- Gamified Virtual Reality Sports Exercise Program, Traditional Sports Exercise Program for Elderly Individuals with Suicidal Thoughts
- Where
- Iran
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Depression
The Effect of Guided ımagery Supported Psychoeducation Applied to ındividuals Diagnosed With Depression on Depression, Self-esteem and Stress Level
Depressive disorder is a common mental disorder. Depression, whose classic symptoms include depressed mood, anxiety, anhedonia and cognitive impairments that profoundly affect quality of life, is one of the leading causes of…
- Trial name
- Depression (NCT07081451)
- Testing
- Guided ımagery supported psychoeducation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kilis 7 Aralik University
Depression, Anxiety
Melissa Officinalis L. Supplementation for Emotional Health and Sleep Disturbance
This study is aimed to investigate if Lemon Balm Extract supplementation is beneficial for the relief of stress, depression and anxiety in healthy adults.
- Conditions
- Depression, Anxiety, Stress, Insomnia
- Trial name
- NCT05602688
- Testing
- Lemon Balm Supplement
- Where
- Pakistan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ayub Teaching Hospital
Diabetes Mellitus, SARS-CoV-2
Anxiety, Depression and Eating Attitudes of Diabetes Mellitus Patients During COVID-19 Lockdown in Greece
The aim of this observational, cross-sectional study is to evaluate the impact of the second national COVID-19 lockdown in Greece, regarding the aspects of depression, anxiety and eating habits, in relation to the adjusted work…
- Trial name
- NCT04700254
- Testing
- DASS questionnaire, EAT-26 questionnaire
- Where
- Greece
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chania General Hospital "St. George"
Temporomandibular Disorder, Temporomandibular Joint Dysfunction
Trauma Exposure and Childhood Trauma in Temporomandibular Joint Disorders
Temporomandibular disorder is a multifactorial condition that involves the temporomandibular joint, masticatory muscles, and surrounding structures and is influenced by biological, psychological, and social factors.
- Conditions
- Temporomandibular Disorder, Temporomandibular Joint Dysfunction, Trauma Exposure, Childhood Traumas
- Trial name
- NCT07292103
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Gulseren Demir Karakilic
Premenstrual Dysphoric Disorder
Combined Effect of Tryptophan Rich Diet and Acupuncture on Depression Related to Premenstrual Dysphoric Disorder
Premenstrual Dysphoric Disorder (PMDD) is a severe form of premenstrual syndrome (PMS) affecting up to 8% of reproductive age women.
- Trial name
- NCT05813366
- Testing
- Acupuncture, Tryptophan-Rich Diet, Vitamin B6 Supplementation
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Menopause
The Effect of Music Therapy on Sleep Quality and Depression in Menopausal Women
About one-third of women experience no or mild symptoms during their menopausal life, while another third experience moderate symptoms, while the remaining one-third may experience severe symptoms.
- Trial name
- NCT05545761
- Testing
- music therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Meryem Vural Şahin
Long COVID, Long COVID Syndrome
Evaluation of MicroRNAs and Vitamin B12 Expression in Subjects with Neurologic Symptoms of Depression, Anxiety and Fatigue in Long COVID-19
At the moment, the number of people with long COVID is unkown because there is still no effective diagnosis. This is why is very important to analyze the most common symptoms, which are: depression, anxiety and fatigue.
- Trial name
- NCT06864156
- Where
- Mexico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Rehabilitacion
Major Depressive Disorder
Phase 1 Evaluation of (2R,6R)-Hydroxynorketamine
A 6-cohort single ascending dose (SAD) study will be conducted in healthy volunteers utilizing a slow-infusion intravenous (IV) route of administration.
- Trial name
- NCT04711005
- Testing
- (2R,6R)-Hydroxynorketamine hydrochloride
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Depression Symptoms, Anxiety Symptoms
Mirror Journaling App Study
This study has three primary aims: 1) Validate Mirror's Mood Check feature by measuring convergent validity;2) Assess user experience and acceptability metrics (e.g., usability, engagement, satisfaction) of the Mirror app, with a…
- Trial name
- Mirror Journal (NCT07126275)
- Testing
- Mirror App Journaling and Mood Tracking Study
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Child Mind Institute
Clinical Depression
Neuromodulation Device Use in Patients With Major Depressive Disorder
Study the neuromodulation device in the treatment of Major Depressive Disorder and associated symptoms. In this study we use the Hamilton Depression Rating Scale (HAM-D), the Quality of Life Scale (QQLS), the Rumination Response…
- Trial name
- NCT04496505
- Testing
- Device
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical Center of Aurora
Aging, Nursing Homes
Effect of Sunlight Exposure and Outdoor Activities on Depression, Cognition and Quality of Life in the Elderly
Background: The transition to long-term care facility can be a stressful and emotional event for the elderly. The evidences showed that the prevalence of depression and the cognition impairment were higher in the…
- Conditions
- Aging, Nursing Homes, Depression in Old Age, Cognitive Impairment
- Trial name
- NCT03304301
- Testing
- sunlight exposure
- Where
- Taiwan
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Chiayi Christian Hospital
Menopause, Depression
Impact of Hot Flashes on Sleep and Mood Disturbance
We plan to enroll premenopausal women in a trial investigating the impact of hot flashes developed in response to an injection of a gonadotropin-releasing hormone agonist (GnRHa), leuprolide (brand name: Lupron), on sleep…
- Conditions
- Menopause, Depression, Hot Flashes
- Trial name
- NCT01116401
- Testing
- leuprolide
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Depression
Brain Energy Metabolism in Individuals With Major Depressive Disorder Receiving Escitalopram
This study will evaluate changes in brain energy metabolism due to treatment with escitalopram in people with major depressive disorder.
- Trial name
- NCT00183677
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Hypovitaminosis D
Vitamin D, Blood Pressure, Lipids, Infection and Depression
There are numerous indications for a relation between low serum levels of 25(OH)D and blood pressure, lipid levels, frequency of infections and tendency towards depression.
- Trial name
- NCT00960232
- Testing
- Cholecalciferol
- Where
- Norway
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Trauma, Nervous System
Northwest Therapies Trauma Psilocybin Study Compassionate Use Study
The on-boarding of unregulatable trauma in the United States has reached 20%, which is 1/5 of the population. A population of this magnitude, by definition has now reached an epidemic classification.
- Trial name
- NWTTPS (NCT05042466)
- Testing
- Trauma
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NWTraumatherapies
Depression, Anxiety
Efficacy of a Brief Intervention to Improve Sexual and Gender Minorities' Mental Health: Randomized Controlled Trial.
Experiences of violence, from micro to physical aggressions, have a deleterious impact on mental health. According to the Minority Stress Theory, unfavorable social conditions (such as anticipated and experienced discrimination…
- Conditions
- Depression, Anxiety, Psychological Distress, Social Phobia
- Trial name
- ESCREVA-SE (NCT05349877)
- Testing
- Expressive writing, Self-affirmation
- Where
- Brazil
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Major Depression, Healthy Participants
Synaptic Mechanisms of Intermittent Theta Burst Stimulation for Major Depressive Disorder
Many people with depression do not get better with standard treatments like medications or talk therapy. Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation treatment that uses magnetic pulses to stimulate…
- Trial name
- NCT07593222
- Testing
- TMS, D-cycloserine, Dextromethophan
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Depression
Personalized Diet-driven Microbiota Alterations as a Tool for Improving Mood Status in Elderly
The propose of the study is a multi-disciplinary project connecting nutritional and health sciences with social and behavioral sciences, and aimed at understanding the microbiota changes related to the third age and their effects…
- Trial name
- NCT03256929
- Testing
- Personalized Diet-driven microbiota, General information on nutrition and health
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tel Hai College
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