Clinical trials: Depressive Disorders
Depression, Anxiety, Alcohol Abuse
Cognitive-Behavioral Therapy for Young Adult Lesbian, Gay and Bisexual: Transdiagnostic Minority Stress Approach
Background: LGB people experience a large number of anxiety and mood disorders, and risk behaviors than heterosexual (Marshall et al., 2011).
- Conditions
- Depression, Anxiety, Alcohol Abuse, Sexual Compulsivity, Unsafe Sex
- Trial name
- NCT03980873
- Testing
- ESTEEM (Effective Sikills to Empower Effective Men)
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Postoperative Pain, Postpartum Depression
Dose Low Dose Ketamine in Casesarian
The results of ketamine, ketamine and midazolom can be copied after birth in cesareans subjected to spinal anesthesia.
- Trial name
- ketamine (NCT06237569)
- Testing
- Application of ketamine and midazolam or ketamine alone to patients undergoing cesarean section under spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Inonu University
Post Traumatic Stress Disorder
Effect of Eye Movement Desensitization and Reprocessing Therapy 2.0 Online Group Protocol
In this study, it will be investigated the efficacy of Eye Movement Desensitization and Reprocessing Therapy 2.0 Online Group Protocol on post-traumatic symptoms compared to control group.
- Trial name
- NCT05596903
- Testing
- EMDR 2.0 group protocol, Mhgap stress module
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Academy of Therapeutic Sciences, Turkey
Bipolar Disorder Type II, Mood Depressive Disorder
Exploration of Differences in Metabolite Concentrations by NMR Spectroscopy in the Ventral Striatum, Anterior Cingulate Cortex and Prefrontal Cortex in Euthymic Patients With Unipolar and Bipolar Type II Mood Disorders, as Well as in Healthy Subjects
The presented project is an open and controlled single-center prospective exploratory study, evaluating the metabolic concentrations in the ventral striatum (VS), the Anterior cingulate cortex (ACC) and the prefrontal cortex…
- Trial name
- RMN-UNIBI (NCT05650788)
- Testing
- NMR spectrometry
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Depression, Substance Use
Building Recovery By Improving Goals, Habits, and Thoughts
The investigators will investigate whether group Cognitive Behavioral Therapy (CBT) for depression, with alcohol and other drug (AOD) treatment counselors leading the groups, is effective and cost effective in treating…
- Trial name
- BRIGHT (NCT01191788)
- Testing
- Group Cognitive Behavioral Therapy, Group CBT for Depression
- Where
- United States
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- RAND
Burnout, Anxiety
Art Therapy to Address Hospital Clinician Burnout
A structured group art therapy intervention, comprising six 60 - 90-minute weekly workshops.
- Conditions
- Burnout, Anxiety, Stress, Depression
- Trial name
- CHArt (NCT05728086)
- Testing
- Group art therapy
- Where
- United Kingdom
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Barts & The London NHS Trust
Major Depression Disorder
Molecular Signatures of TMS Response in Treatment-Resistant Depression
Transcranial Magnetic Stimulation (TMS) therapy is an approved and effective treatment option for treatment-resistant depression (TRD).
- Trial name
- PROMET_TMS (NCT07039370)
- Testing
- TMS
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Depression Disorders
Prevalence and Severity of Depression Among Cardiothoracic Surgery Healthcare Workers in Baghdad: A PHQ-9 Cross-Sectional Study
This observational study aims to estimate the prevalence and severity of depression in HCWs in cardiothoracic surgery departments in Baghdad City, Iraq, using a self-administered PHQ-9 questionnaire.
- Trial name
- DEPRESS/PHQ-9 (NCT06702761)
- Where
- Iraq
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Al-Nahrain University
Stress Disorders, Post-Traumatic, Depressive Disorder
Promoting Attachment Through Healing
Intimate partner violence (IPV) is a significant and pervasive public health challenge and is associated with mental illnesses such as depression, anxiety and posttraumatic stress disorder (PTSD).
- Conditions
- Stress Disorders, Post-Traumatic, Depressive Disorder, Anxiety Disorders
- Trial name
- PATH (NCT03536442)
- Where
- Canada
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Sleep Initiation and Maintenance Disorders, Depression
Estrogen for Treating Depression in Menopausal Women With Hot Flashes and Insomnia
This study will evaluate the effectiveness of estrogen replacement therapy in treating depression in menopausal women with hot flashes and insomnia.
- Trial name
- NCT00227942
- Testing
- Estrogen Replacement Therapy, Zolpidem
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Hadine Joffe, MD
Anxiety, Depression
Risk Factors for Anxiety and Depression Among Pregnant Women During the COVID-19 Pandemic
The article presents a protocol of a cross-sectional study of mental health of pregnant women in relation to the COVID 19 pandemic.
- Conditions
- Anxiety, Depression, Pregnancy Related
- Trial name
- MindCOVID (NCT04377412)
- Testing
- Pandemic control measures
- Where
- 17 sites in United States, Albania and 13 more
- Volunteers
- 8,500 people, healthy volunteers welcome
- Sponsor
- Żelazna Medical Centre, LLC
Loneliness, Depression
Humanoid Robot vs Treatment as Usual for Loneliness
The investigators are aiming to compare the effects of a humanoid robot intervention to treatment as usual, on loneliness and mental health outcomes in older adults living in long-term care, through an assessor-blinded randomized…
- Conditions
- Loneliness, Depression, Stress, Anxiety
- Trial name
- NCT05423899
- Testing
- Grace Robot, Treatment as Usual
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lady Davis Institute
Smoking Cessation
Nicotine Patch Trial in Syrian Primary Care Settings
The study is a two-arm, parallel group, randomized, placebo-controlled, double blind trial, conducted at four primary health care centers in Aleppo, Syria, to test the efficacy of transdermal nicotine patch therapy vs.
- Trial name
- NCT01085032
- Testing
- Transdermal Nicotine
- Where
- Syria
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Mindfulness, Depression
Internet-based Mindfulness-based Training (iMBT) for People With Depression
The research goals of this randomized controlled trial are to determine the feasibility and the mechanism of change of iMBT that has been developed using the Acceptance Checklist for Clinical Effectiveness Pilot Trials.
- Trial name
- NCT05410132
- Testing
- Internet-delivered Mindfulness Based Training (iMBT)
- Where
- Hong Kong
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Postmenopause
Effects of Breathing Training on Psychosocial Functioning and Heart Rate Variability in Postmenopausal Women With Depressive Symptoms-2
The specific aims of this study are: 1. To develop a breathing training protocol specifically designed to improve HRV and psychosocial functioning for postmenopausal women with depressive symptoms, 2.
- Trial name
- NCT01046149
- Testing
- Breathing training, Stress management
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Science and Technology Council, Taiwan
Anxiety Disorders, Depressive Disorder
Islamic-Oriented vs. Standard Ericksonian Hypnotherapy for Anxiety and Depression
This randomized controlled trial (RCT) aims to compare the effectiveness of Islamic-Oriented Ericksonian Hypnotherapy (IEH) and Standard Ericksonian Hypnotherapy (SEH) in reducing symptoms of anxiety and depression.
- Trial name
- IEH-RTC (NCT06844058)
- Testing
- Islamic-Oriented Ericksonian Hypnotherapy (IEH), Standard Ericksonian Hypnotherapy (SEH)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Nisantasi University
Depressive Disorder, Depression - Major Depressive Disorder
A Qualitative Analysis of Youth Responses to Depression Education Delivered on Social Media
Depression is a common mental disorder among adolescents, with increased rates during the COVID-19 pandemic. Despite its high burden, few young people seek professional help due to, among other things, low mental health literacy…
- Conditions
- Depressive Disorder, Depression - Major Depressive Disorder, Depression in Adolescence
- Trial name
- NCT07100548
- Testing
- "ich bin alles" (English: "I am everything")
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Stress-related Problem, Depression, Anxiety
Harlem Strong Mental Health Coalition
Addressing health disparities, especially in the face of coronavirus pandemic, requires an integrated multi-sector equity-focused, community-based approach.
- Conditions
- Stress-related Problem, Depression, Anxiety, Mental Health Wellness
- Trial name
- NCT05833555
- Testing
- MH task-sharing training, Supervision, Learning Collaborative
- Where
- 2 sites in United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- City University of New York, School of Public Health
Cardiovascular Diseases, Cardiovascular Risk Factor
Cooking for Health Optimization With Patients
Cooking for Health Optimization with Patients (CHOP) is the first known multi-site prospective cohort study with a nested Bayesian adaptive randomized trial in the preventive cardiology field of culinary medicine.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Nutrition Disorders, Diabetes
- Trial name
- CHOP (NCT03443635)
- Testing
- Treatment
- Where
- United States
- Volunteers
- 7,192 people, healthy volunteers welcome
- Sponsor
- Tulane University
Major Depressive Disorder
A Study of LY2216684 and Digoxin in Healthy Subjects
The purpose of this study is to determine how much digoxin gets into the blood stream and how long it takes the body to get rid of it when given with LY2216684.
- Trial name
- NCT01266590
- Testing
- LY2216684, Digoxin
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
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