Clinical trials: Dermatologic
Lean Muscle Development, Muscular Endurance
A Clinical Trial to Evaluate the Effects of a Powder Supplement in Supporting Lean Muscle Development, Hormone-Related Wellness, Digestive Comfort, Dermatologic Health, and Overall Wellness
This study will evaluate the effects of Clean Nutra's Shelf Builder Women's Creatine Powder on lean muscle development, hormone-related wellness, digestive comfort, dermatological health, and overall wellness.
- Conditions
- Lean Muscle Development, Muscular Endurance, Hormone-Related Wellness, Digestive Comfort
- Trial name
- NCT07766395
- Testing
- Shelf Builder Women's Creatine Powder
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Clean Nutraceuticals
Venomous Snakebites, Local Anesthesia
Subcutaneous Injection of Large Volumes of Tumescent Lidocaine and Epinephrine by Laypersons
This research is intended to show that it is safe and not difficult for nearly anyone to inject at least 125ml of a dilute solution of tumescent lidocaine and epinephrine (TLE), where a TLE solution consists of lidocaine (1gm/L)…
- Conditions
- Venomous Snakebites, Local Anesthesia, Painless Injection, Regional Anesthesia
- Trial name
- TLE-RCT (NCT04733781)
- Testing
- Tumescent Lidocaine and Epinephrine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Jeffrey Alan Klein, MD
Local Anaesthetic Complication, Pain
Kinetic Anesthesia Device Study
Patients experience discomfort from lidocaine injections. Vibrating kinetic anesthesia devices (KAD) have been shown to reduce pain of injections in dentistry, pediatrics, and dermatology, though no studies of lidocaine…
- Trial name
- NCT03344510
- Testing
- Kinetic Anesthesia Device, Control
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Dermatologic Disorders, Disorder of Cholesterol Metabolism
Confocal Raman Spectroscopy: in Vivo Measurement of Physiological Skin Parameters
The purpose of this study is to I. determine several skin parameters, for example natural moisturizing factor (NMF) and cholesterol, with Raman spectroscopy in vivo and II.
- Trial name
- NCT02854475
- Testing
- Venous blood collection, Raman spectroscopy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Dermatologic Complications
Preliminary Study of Peel Force and Discomfort of Removal of Adhesive Barriers in Normal and Peristomal Skin
This purpose of this study is to look at three commercially available ostomy barriers on peristomal (around the stoma) skin. Repeated barrier application and removal over years causes changes to the skin that the investigators…
- Trial name
- NCT02003404
- Testing
- Control Abdominal Skin, Peristomal Abdominal Skin
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Hollister Incorporated
Skin Cancer, Skin Wound
Preoperative Image-based Education Effect on Postoperative Satisfaction of Patients Undergoing First-time Dermatologic Surgery
This research study aims to understand whether visual and written education on wound appearance can improve patients' experience and understanding of what their wound will look like following dermatologic surgery.
- Trial name
- NCT05643755
- Testing
- Preoperative image-based education
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Pain
Pain Perception: Lidocaine Rate/Temp/Buffer
This study will collect data from multiple academic institutions. The primary objective for part A of this study is to determine the impact of anesthetic injection rate and temperature on pain perception during dermatologic…
- Trial name
- NCT02823002
- Testing
- Slow, Room Temperature Injection, Rapid, Room Temperature Injection, Slow, Warm Temperature Injection
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Sutured Wounds
A Comparison Study of the Tensile Strength of Sutures Used in Dermatologic Surgery on the Day of Suture Removal, Following Wound Care With Two Different Products
Sutures are an integral part of surgery and available materials are diverse, as are the options for post-procedure care. Both saline and hydrogen peroxide are commonly used cleansing agents.
- Trial name
- NCT01533675
- Testing
- Hydrogen peroxide, Saline
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Miami
Dermatologic Disorders, Injury Due to Laser
Assessment of Needs of Moisturizers After Various Laser Treatments
Assessment of needs of moisturizers after various laser treatments
- Trial name
- NCT01742247
- Testing
- Physiogel, Moisturizer
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital
Periorbital Wrinkles
Safety and Efficacy of XP200 Radiofrequency Treatment of Wrinkles
To evaluate the wrinkle-reducing effects of 3.25-MHz radiofrequency (RF) energy delivered in 4 weekly applications to human periorbital skin area by grating pre- and 90-days post treatment photographs on the Fitzpatrick Wrinkle…
- Trial name
- NCT01795417
- Testing
- RF XP200, XP200 RF device
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
This Study Will Focus on In-office Dermatological Procedures
Split Face Study of the Duration of Local Anesthetics - Fifth Arm
This study will compare how long local anesthesia lasts when it is injected into different layers of the skin on the forearm. The investigators hypothesize that the numbing effect will last for different amounts of time depending…
- Trial name
- NCT07724418
- Testing
- Lidocaine HCl/Epinephrine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Pain, Anxiety
Music and Local Anesthesia During Dermatologic Procedures
The goal of the study is to determine the effect of classical music on participants pain and anxiety associated with lidocaine administration during routine standard of care dermatologic procedures.
- Trial name
- NCT04317170
- Testing
- Music
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Anesthesia, Local
Split Face Study of the Duration of Local Anesthetics - Fourth Arm
This is a research study to compare how long injectable pain medications (anesthetics) commonly used in dermatologic surgery are effective for.
- Trial name
- NCT06694714
- Testing
- 0.5 ml lidocaine + epinephrine 1:100,000, 1.0 ml lidocaine + epinephrine 1:100,000
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Dermatologic Disease
Serotonin Levels in Atopic Dermatitis Patients
Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease of unknown aetiology. Global prevalence rates range from 1%-20%.AD is often worsened by stress and anxiety.Plasma levels of 5-HT were found to be positively…
- Trial name
- NCT03471819
- Testing
- Serum serotonin level
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Familial Lipomatosis, Very Rare Dermatologic Diseases
Identification of Mutations Responsible for Rare Familial Skin Diseases by Next Generation Sequencing
The primary purpose of the protocol is to use next generation sequencing to identify pathogenic variants in genes involved in very rare skin diseases.
- Trial name
- DERMA-SEQ (NCT02509650)
- Where
- 2 sites in France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Inflammatory Disease, Immune System Disorder
Cross-condition Validation of the Steroid PRO
Testing a questionnaire about treatment with steroids for skin, lung or gastric conditions
- Conditions
- Inflammatory Disease, Immune System Disorder, Gastrointestinal Diseases, Dermatologic Disease
- Trial name
- NCT06314451
- Testing
- Cognitive Interview
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of the West of England
Laxity of Skin
Investigation of Radiofrequency Device for Treatment of Wrinkles and Rhytides
The purpose of this pilot research study is to collect information on the safety and effectiveness of an experimental device intended to be used to improve the appearance of the skin by reducing the visibility of wrinkles and by…
- Trial name
- NCT01279226
- Testing
- Auralevée device
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rocky Mountain Biosystems, Inc.
Suture, Suture Dermatologic
Effect of Petrolatum Coating on Fast-absorbing Gut Suture
This study is designed to evaluate the effect of using petrolatum to coat gut suture. This coating is commonly performed to make the suture more easy to handle; however, it was unknown if it affects the absorption rate of the…
- Conditions
- Suture, Suture Dermatologic, Mohs Micrographic Surgery, Suture Techniques
- Trial name
- NCT07127029
- Testing
- Petrolatum coating of fast-absorbing gut suture
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- San Antonio Uniformed Services Health Education Consortium
Medication Adherence
Antibiotic Adherence Practices in Dermatologic Surgery
This multi-center prospective observational cohort study will examine the prevalence of non-adherence along with analyze the risk factors of non-adherence for patients presenting to dermatologic surgery.
- Trial name
- NCT04117724
- Testing
- Survey
- Where
- 9 sites in United States
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Surgical Site Infection, Patient Satisfaction
Effect of Surgical Site Infections on Patient Reported Cosmetic Outcomes in Dermatologic Surgery
This study involves surveying two matched groups of patients that underwent dermatologic surgery at our department. One group had a documented surgical site infection and the other didn't.
- Trial name
- NCT04744961
- Testing
- SCAR-Q survey
- Where
- Sweden
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Region Skane