Clinical trials: Development Disorders
Tuberous Sclerosis Complex (TSC), Focal Cortical Dysplasia
Phase 1, Open-label, Drug-drug Interaction Study to Assess Effect Between Radiprodil and the Co-administered Drugs.
This is a Phase 1, open-label, 3-period study to determine radiprodil's potential to act as a perpetrator of cytochrome P-450 (CYP) metabolic pathways and transporter pathways.
- Conditions
- Tuberous Sclerosis Complex (TSC), Focal Cortical Dysplasia, Other Neurological Disorders
- Trial name
- NCT06975605
- Testing
- Radiprodil + co-administered drugs
- Where
- Australia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GRIN Therapeutics, Inc.
Celiac Disease in Children, Celiac Disease
Development of CELIAC-Q KIDS: A Patient-Reported Outcome Measure for Pediatric Celiac Disease
A multicentre, prospective observational study to develop the CELIAC-Q KIDS patient reported outcome measure for children and adolescents with celiac disease.
- Conditions
- Celiac Disease in Children, Celiac Disease, Patient-reported Outcome Measures
- Trial name
- NCT05548166
- Testing
- Interview and scale development
- Where
- 2 sites in Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- McMaster University
Gender Dysphoria
Developmental Correlates and Hormone Therapy Effects in Gender Dysphoria
The aim of the research is to study longitudinally the effects of reassignment hormonotherapy on the connectome of MtF (biological men who are transitioning to the female gender) dysphoric subjects after 6 months of hormone…
- Trial name
- DCHGD (NCT04309760)
- Testing
- MRI
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Clinical Reasoning, Critical Illness
The Effect of Case-Based Education on the Development of Nursing Students' Clinical Reasoning Skills
Aim: This study was conducted to determine the effect of case-based education on the development of clinical reasoning skills of nursing students in critical illnesses.
- Trial name
- NCT05504824
- Testing
- Case-based education
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ankara University
ADHD - Attention Deficit Disorder With Hyperactivity, ADHD
Research on the Development, Implementation Effect and Neural Mechanism of a Physical Intervention Program for College Students With ADHD Based on the Characteristics of Balance Dysfunction
Background: Attention deficit/hyperactivity disorder is a common neurodevelopmental disorder. Its core symptoms and related executive function, emotional and motor coordination problems often persist into adulthood, significantly…
- Conditions
- ADHD - Attention Deficit Disorder With Hyperactivity, ADHD, ADHD - Combined Type, ADHD - Inattentive Type
- Trial name
- NCT07499427
- Testing
- Aerobic Treadmill Training, Progressive Balance Training, Cognitive-Balance Dual-Task Training
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Wuhan Sports University
Term, Healthy
Effectiveness of a Training Program for Parents of Babies in Their First Year of Life to Achieve Motor Milestones
this study compares motor development of two groups of healthy term babies at the end of their first year of life. Parents of the intervention group have received a training program consisting in advices about correct positions…
- Conditions
- Term, Healthy, Motor Delay, Development, Infant
- Trial name
- NCT04693494
- Testing
- Training program
- Where
- Spain
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Universidad San Jorge
Mental Health Impairment, Substance Abuse
Recovery - a Collaborative Project
In Norway, official guidelines and policies state that recovery oriented services in the field of mental health and substance abuse services is a desirable goal.
- Trial name
- NCT04138459
- Testing
- Not an interventional study. This is a qualitative, explorative study of recovery orientation of community mental health services
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University College of Southeast Norway
Diabetes, Diabetes Mellitus, Type 2
A Trial Investigating the Possible Difference in Development of Type 2 Diabetes Between Caucasian and Japanese Subjects
This trial is conducted in Europe and Japan. The aim of this clinical trial is to investigate the possible difference in the development of type 2 diabetes in a Japanese and a Caucasian population.
- Trial name
- NCT00897169
- Testing
- Oral Glucose Tolerance Test (OGTT), Euglycaemic hyperinsulinaemic clamp
- Where
- 2 sites in Denmark, Japan
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Neurodevelopment Outcome, Linear Growth
Micronutrient Enhancement for Development and Health in Adolescents - The MEDHA Study
MEDHA is a randomized controlled trial among 10-18 year old girls to examine the use-case of the United Nations International Multiple Micronutrient Antenatal Preparation (UNIMMAP) multiple micronutrient supplement (MMS)…
- Conditions
- Neurodevelopment Outcome, Linear Growth, Micronutrient Status, Bone Mineral Density
- Trial name
- MEDHA (NCT07695883)
- Testing
- Iron (60 mg)- folic acid (400 ug) [IFA], Multiple micronutrient supplement [MMS], Multiple micronutrient supplement Plus [MMS+]
- Where
- Bangladesh
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Overweight and Obesity
Feasibility of Technology Mediated Lifestyle Intervention for Overweight and Obese Young Adults
Rashakaty (Fitness for Me) study aimed to design a new technologies-based intervention using a website and smart phone applications and to test the feasibility of implementing a lifestyle intervention using these technologies for…
- Trial name
- Rashakaty (NCT04919759)
- Testing
- R-Basic, R-Enhanced
- Where
- United Arab Emirates
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- United Arab Emirates University
Atrial Fibrillation, Arrythmia
Design and Rationale of the Assessment of the MindMics Recording System
MindMics earbuds is a new technology designed enhance an individual's quality of life by continuously monitoring the heart rate, stress, and blood pressure allowing patients to make decisions regarding their health.
- Trial name
- NCT05103579
- Testing
- MindMics
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- MindMics Inc
Autism
Parent Language Intervention for Autism
Improving social communication outcomes for children with autism spectrum disorders (ASD) has important public health implications.
- Trial name
- NCT02632773
- Testing
- Responsive Intervention, Directive Intervention
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Autistic Disorder
A Chart Review to Evaluate the Safety and Efficacy of MeRT on Subjects With ASD
The purpose of this study is to evaluate the safety and efficacy of Magnetic EEG/ECG-Guided Resonance Therapy (MeRT) on subjects with Autism Spectrum Disorder (ASD).
- Trial name
- NCT02758496
- Testing
- MeRT Efficacy Chart Review
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Wave Neuroscience
Developmental Coordination Disorder
Rhythmic Interlimb Coordination in Children with Developmental Coordination Disorder
This study is a case-controlled observational study, involving children with Developmental Coordination Disorder (DCD) and typically developing children with an age from 8 up to 12 years old.
- Trial name
- NCT04891562
- Testing
- interlimb coordination of the lower limbs and synchronization
- Where
- Belgium
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Stuttering, Developmental, Dyslexia
Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech
This study aims to understand how people use different types of feedback to control their speech. When an individual speaks, the brain relies on several systems at the same time, such as sensory systems that monitor an…
- Conditions
- Stuttering, Developmental, Dyslexia, Healthy Participants
- Trial name
- NCT07459803
- Testing
- Unpredictable auditory feedback perturbation: 2 behavioral sessions, Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions, Sustained F1 auditory feedback perturbation
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Calculus, Dental, Periodontal Diseases
Development of a New Toothpaste for the Removal of Dental Calculus.
Periodontal disease is amongst the most prevalent oral diseases worldwide and in North America. According to the 2007/09 Canadian Health Measures Survey, 16% of Canadian adults and 24% of older adults, 60 to 79 years of age, were…
- Conditions
- Calculus, Dental, Periodontal Diseases, Periodontal Inflammation
- Trial name
- NCT04381403
- Testing
- Bio-descaling D-Tart toothpaste, Crest® toothpaste
- Where
- Canada
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Faleh Tamimi
Retardation, Fetal Growth, Macrosomia, Fetal
Antenatal Development Evaluated Prospectively
Fetal growth abnormalities is one of the most common problems faced in modern obstetrics. The association between low birth weight and perinatal death as well as severe morbidity is well known.
- Trial name
- ADEPT (NCT02478554)
- Testing
- Customized fetal growth curves
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Developmental Stuttering, Evoked Potentials Auditory
Effect of Stuttering Remediation Exercises on Cortical Auditory Evoked Potentials
studying how the cortical auditory evoked potentials differ in children who stutter from who do not stutter and how these potentials change with therapy
- Trial name
- NCT05473572
- Testing
- Fluency shaping exercises
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Alaa Mamdouh
Autism, Attention Deficit Hyperactivity Disorder
a2 Milk for Autism and Attention-deficit Hyperactivity Disorder (ADHD)
Under double-blind, placebo-controlled, cross-over conditions, the short-term effects of use of A1 beta casein free milk (a2 milk) and milk containing A1 beta casein will be compared in a sample of pre-pubescent boys diagnosed…
- Conditions
- Autism, Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
- Trial name
- A2MT (NCT02911194)
- Testing
- a2 milk, a1 containing milk
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Thalassemia
Development of THALEA Kit and Its Impact on Knowledge, Attitude, and Intention for Premarital Thalassemia Screening
Thalassemia, a common genetic disease, is often overlooked compared to infectious diseases like HIV, despite its significant effects for families planning to have children.
- Trial name
- THALEA (NCT06800495)
- Testing
- THALEA (Thalassemia Education and Awareness) Kit, Basic thalassemia and family health education
- Where
- Malaysia
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Universiti Teknologi Mara
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