Clinical trials: Development Disorders
Femoroacetabular Impingement, Hip Developmental Dysplasia
Cross-sectional Study of Ultrasonic Diagnosis of Iliac Joint Capsule Muscle
In order to investigate the relationship between the iliac joint capsular muscle and the development of the hip joint, this study used ultrasound Doppler to measure the anatomical circumference of the iliac joint capsular muscle…
- Trial name
- NCT04968301
- Testing
- ultrasound Doppler
- Where
- China
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Pregnancy, Sexually Transmitted Diseases
Development and Testing of a Clinic-Based Intervention to Increase Dual Protection Against Unintended Pregnancy and Sexually Transmitted Diseases (STDs) Among High Risk Female Teens
This trial will evaluate a multi-component, clinic-based intervention aimed at increasing dual protection strategy selection and adherence among young African American females at an urban family planning clinic.
- Trial name
- 2Gether (NCT02291224)
- Testing
- Interactive multimedia platform, Intervention arm counseling, Standard of care counseling
- Where
- United States
- Volunteers
- 709 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Preterm Infant, Physical Therapy
Early Physical Therapy Intervention in Preterm Infants
The hypothesis of this study is that early physical therapy intervention, initiated during the NICU stay and up to 2 months corrected age, based on the family-centered model, could promote preterm infants motor development in…
- Conditions
- Preterm Infant, Physical Therapy, Early Intervention, NICU
- Trial name
- NCT03313427
- Testing
- Physical Therapy Early Intervention, Usual Care
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Developmental Coordination Disorder
Effect of tDCS on Postural Control of Children With DCD
This study investigates the effects of Transcranial Direct Current Stimulation (tDCS) on postural control of children with Developmental Coordination Disorder (DCD).
- Trial name
- NCT03892083
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Gestational Diabetes Mellitus (GDM)
The Role of Breast Milk Neutrophils From Mothers With Metabolic Diseases After Nutritional Intervention. Impact on Infant Development and Response to Pulmonary Infections
This project aims at identifying variations in breast milk neutrophils among lactating mothers with gestational diabetes or obesity (objective 1), and to describe how a dietary intervention with Omega-3 fatty acids affects these…
- Trial name
- PI2222/01813 (NCT06833554)
- Testing
- Omega-3 Fatty Acids (EPA plus DHA)
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Anxiety, Pain, Postoperative
Nursing Intervention Program in the Management of Parental Anxiety and Infant Pain in the Surgical Process of Children to be Circumcised
Entering the hospital and waiting for surgery is a very stressful time for people. According to some studies, surgical interventions in children generate in family members concerns related to: anesthesia, fear of being harmed…
- Conditions
- Anxiety, Pain, Postoperative, Child Development
- Trial name
- NCT05387291
- Testing
- Intervention group, Control group
- Where
- Spain
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Universitat de Girona
Hepatitis B
Characterisation of Human B Cell Maturation in Response to Vaccination
This study is an exploratory single site sample collection study at St Mary's hospital campus, Imperial College London. Sixteen participants scheduled to receive routine immunizations for Td/IPV (group 1) and HBsAg (group 2) will…
- Trial name
- BVAC (NCT03535779)
- Testing
- Hepatitis B, Tetanus Toxoid
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Obesity
Prevention of Childhood Obesity
This study is conducting preliminary testing to find out whether a particular educational program can alter parental overcontrol of their children's eating.
- Trial name
- NCT00788203
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Stanford University
Hypogonadism
Effect of Varying Testosterone Levels on Insulin Sensitivity in Normal and IHH Men
Type 2 diabetes is one of the most common metabolic disorders in the U.S, estimated to affect 16 million Americans. Established risk factors for this disease include obesity, increased waist/hip ratio, high insulin levels in the…
- Trial name
- NCT00470990
- Testing
- GnRH antagonist (Acyline)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Premature Birth, Infant, Newborn
Orofacial Development of Preterm and Low Birthweight Infants Versus Term Infants
Preterm infants account for 6 % of all live-births in western societies. Scientific evidence can be found for altered palatal morphology in the short term among preterm children.
- Conditions
- Premature Birth, Infant, Newborn, Pregnancy
- Trial name
- NCT00408746
- Testing
- palatal development
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Polycystic Ovary Syndrome, Insulin Resistance
Acupuncture or Metformin for Insulin Resistance in Women With PCOS
The hypothesis is that acupuncture is equally effective as metformin (both treatments combined with lifestyle management) in improving whole body glucose homeostasis in insulin resistant women with polycystic ovary syndrome…
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Hyperandrogenism
- Trial name
- PIAII (NCT02647827)
- Testing
- Lifestyle management, Acupuncture, Metformin
- Where
- 2 sites in China, Sweden
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Anemia, Herbal Interaction
Development of PHY606 as Adjunct Therapy for Anemia Patients
Many reasons can cause anemia, decreased RBC production or increased destruction of circulation RBC. The investigators investigate the Danggui Buxue Tang (PHY606) composed of Angelicae Sinensis Radix and Astragali Radix in the…
- Trial name
- NCT04974073
- Testing
- PHY606
- Where
- Taiwan
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Sheng-Teng Huang
Ageing Signs, Cognitive Decline
Anti-Ageing Health Supplement From Ginger Extracts
This study examines the development and efficacy of a health supplement derived from ginger using water extraction. Designed to address aging-related issues such as muscle loss (sarcopenia) and cognitive decline, the capsule's…
- Conditions
- Ageing Signs, Cognitive Decline, Musculoskeletal
- Trial name
- NCT06828783
- Testing
- ginger extract
- Where
- Malaysia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Phelan-McDermid Syndrome, Autism Spectrum Disorder
Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome
The purpose of this study is to comprehensively characterize PMS using standardized medical, cognitive, and behavioral measures and to track the natural history of the syndrome using repeated longitudinal assessments.
- Conditions
- Phelan-McDermid Syndrome, Autism Spectrum Disorder, Intellectual Disability
- Trial name
- NCT02461420
- Where
- 5 sites in United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Parents, Stress
Telehealth Mindfulness-Based Music and Songwriting for Parents of Children With Intellectual/Developmental Disabilities
This is a pilot study of the feasibility and potential impact of a Mindfulness-Based Music and Songwriting program (delivered via telehealth) on stress and well-being in parents/caregivers of children with intellectual or…
- Conditions
- Parents, Stress, Developmental Disability, Intellectual Disability
- Trial name
- NCT04962659
- Testing
- Mindfulness-Based Music and Songwriting
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Craniosynostoses
Neurodevelopmental Outcomes in Craniosynostosis Repair
Context: Craniosynostosis is a common craniofacial abnormality which can be associated with various clinical syndromes. Though it has been established that children with craniosynostosis score lower on certain developmental…
- Trial name
- NCT04072783
- Testing
- MRI,DTI, functional MRI
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Diabetes, Prediabetes
Meta-analyses of Pasta as Part of Low Glycemic Index Diets and Adiposity
Pasta is an important example of a food which can lower the glycemic index (GI) of the diet, a property that has been exploited extensively in studies of low GI dietary patterns.
- Conditions
- Diabetes, Prediabetes, Overweight, Obesity
- Trial name
- NCT02961088
- Testing
- Pasta as part of a low GI/GL diet
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Prenatal Exposure Delayed Effects
Nutrition and Inflammation in Pregnancy: Impacts on Early Human Brain Development in Ethiopia
The goal of this observational child follow-up study is to examine the effects of prenatal nutrition and infection management interventions on long-term child neurodevelopment.
- Trial name
- NCT06296238
- Where
- Ethiopia
- Volunteers
- 463 people, healthy volunteers welcome
- Sponsor
- Brown University
Healthy, Hypertrophic Cardiomyopathy
Investigation Into the Use of Ultrasound Technique in the Evaluation of Heart Disease
The human heart is divided into four chambers. One of the four chambers, the left ventricle, is the chamber mainly responsible for pumping blood out of the heart into the circulation.
- Conditions
- Healthy, Hypertrophic Cardiomyopathy, Left Ventricular Hypertrophy
- Trial name
- NCT00001632
- Where
- United States
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Multiple Sclerosis
DreaMS - Digital Biomarkers for Multiple Sclerosis
The Investigators have developed the dreaMS App, a data communication platform collecting data from the patients' mobile devices (smartphone and wearables).
- Trial name
- DreaMS (NCT04413032)
- Testing
- DreaMS
- Where
- Switzerland
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Research Center for Clinical Neuroimmunology and Neuroscience Basel
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