Clinical trials: Diabetes Mellitus, Experimental
Diabetes Mellitus, Type 2
A Study of the Efficacy and Safety of Dulaglutide (LY2189265) in Participants With Type 2 Diabetes
The purpose of this study is to evaluate the efficacy and safety of investigational doses of once weekly dulaglutide when added to metformin in participants with type 2 diabetes with inadequate blood sugar control.
- Trial name
- AWARD-11 (NCT03495102)
- Testing
- Dulaglutide
- Where
- 208 sites in United States, Argentina and 14 more
- Volunteers
- 1,842 people
- Sponsor
- Eli Lilly and Company
Diabetes
Evaluation of an Ascensia Diabetes Care ONYX PLUS Investigational Blood Glucose Monitoring System
The purpose of this study was to determine if untrained subjects with diabetes can operate the Investigational ONYX PLUS Blood Glucose Monitoring System (BGMS) and obtain valid glucose results.
- Trial name
- NCT02371876
- Testing
- ONYX PLUS Investigational Blood Glucose Monitoring System
- Where
- 2 sites in United States
- Volunteers
- 134 people
- Sponsor
- Ascensia Diabetes Care
Diabetes Mellitus, Experimental
Cardiometabolic Effects of Rapid Glucose Excursion
The effects of rapid glucose excursions, induced by intravenous bolus application of glucose in healthy probands, on cardiometabolic and inflammatory parameters will be investigated
- Trial name
- ERGE (NCT04488848)
- Testing
- bolus glucose, continuous clucose
- Where
- Austria
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Barmherzige Brüder Linz
Diabetes Mellitus
Evaluation of the Effects of Heating the Vicinity of the Insulin Delivery Site by the Experimental Device
The study is an open-label, randomized, two-period, one-way crossover study using the Meal Tolerance Test (MTT) protocol or the daily life setting protocol. The study consists of two parts.
- Trial name
- NCT02306343
- Testing
- InsuPad
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Insuline Medical Ltd.
Diabetes
Study of an Investigational Glucose Meter System
The purpose of this study is to demonstrate that untrained subjects who have diabetes can operate the Investigational Blood Glucose Monitoring System (BGMS) and obtain valid glucose results.
- Trial name
- NCT01474317
- Testing
- G3 Investigational Blood Glucose Monitoring System
- Where
- 2 sites in United States
- Volunteers
- 226 people
- Sponsor
- Ascensia Diabetes Care
Solid Tumor, Lymphoma
PROCLAIM-CX-072: A Trial to Find Safe and Active Doses of an Investigational Drug CX-072 for Patients With Solid Tumors or Lymphomas
The purpose of this first-in-human study of CX-072 is to characterize the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and antitumor activity of CX-072 administered intravenously (IV) as a single agent or in…
- Trial name
- NCT03013491
- Testing
- CX-072, ipilimumab, vemurafenib
- Where
- 31 sites in United States, Netherlands and 4 more
- Volunteers
- 196 people
- Sponsor
- CytomX Therapeutics
Diabetes
Evaluation of an Karajishi Contour Investigational Blood Glucose Monitoring System
The purpose of this study is to determine if subjects who have diabetes can operate the Investigational Blood Glucose Monitoring System (BGMS) without training and obtain valid glucose results.
- Trial name
- NCT02041286
- Testing
- Karajishi Contour Investigational BG Monitoring System
- Where
- 2 sites in United States
- Volunteers
- 136 people
- Sponsor
- Ascensia Diabetes Care
Diabetes Mellitus
Clinical Experimental Study to Investigate Specific Features of ClampArt®
A single centre, clinical experimental study. Every subject will undergo clamp experiments, where a clamp device (ClampArt®) measures and controls the blood glucose concentration after administration of marketed insulin products.
- Trial name
- NCT01906970
- Testing
- ClampArt
- Where
- Germany
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Profil Institut für Stoffwechselforschung GmbH
Diabetes Mellitus, Type 2
An Investigational Drug Study in Patients With Type 2 Diabetes Mellitus (0431-024)
The purpose of this investigational study is to determine the safety and effectiveness of an investigational drug in patients with type 2 diabetes mellitus (a specific type of diabetes).
- Trial name
- NCT00094770
- Testing
- sitagliptin (MK0431), Comparator: glipizide
- Volunteers
- 1,172 people
- Sponsor
- Merck Sharp & Dohme LLC
Type 2 Diabetes
Comprehensive Care Protocol in New Diagnosis of Type 2 Diabetes Mellitus and Associated Comorbidities in Primary Care
Introduction Type 2 Diabetes is a very prevalent chronic disease in our environment. It usually exists with other chronic diseases.
- Trial name
- PICDM2 (NCT03990857)
- Testing
- Comprehensive care protocol in new diagnosis of Type 2 Diabetes Mellitus and associated comorbidities in Primary Care
- Where
- Spain
- Volunteers
- 123 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Diabetes Mellitus, Type 1
Diabetes Technology Study of Real-Time Glucose Alerts in the Team Management of Diabetes
Many people with diabetes have a desire to share blood glucose data with other members of their team. Using a unique wireless glucose meter device, real-time wireless alerts may be automatically sent to a specific team of…
- Trial name
- NCT00322478
- Testing
- Automated informatics driven education and social networking, Blood Glucose Notifications to Remote Caregivers, Frequency of Pattern Management
- Where
- United States
- Volunteers
- 432 people
- Sponsor
- Diabetech
Prediabetes / Type 2 Diabetes
A Clinical Trial to Examine the Efficacy and Safety of an Investigational Product With and Without Use of Semaglutide on Glycemic Response in Adults With Prediabetes or Type 2 Diabetes
This is a randomized, single-blind, controlled, parallel clinical trial to examine the efficacy and safety of AMPK Charge+® with and without use of semaglutide on glycemic response in adults with prediabetes or Type 2 Diabetes.
- Trial name
- NCT07195994
- Testing
- AMPK Charge+®, AMPK Charge+® with semaglutide
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- QuickSilver Scientific
Type 2 Diabetes Mellitus
A 6-Week Study To Determine The Safety And Effect Of An Investigational Drug On Adults With Type 2 Diabetes Mellitus Taking Metformin
A Phase 2a study to evaluate the effects of an investigational compound administered at 200 mg, twice daily (BID), for 6 weeks in adult subjects with Type 2 Diabetes Mellitus (T2DM) on metformin background therapy.
- Trial name
- NCT02053103
- Testing
- PF-05175157
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Pfizer
Diabetes, Gestational, Pre-eclampsia
Usability Evaluation of Gen AI-based Nutrition Chatbot for Pregnant Women
Background: Pregnancy imposes significant physical demands, with complications like gestational diabetes (GDM) and pre-eclampsia posing serious risks.
- Conditions
- Diabetes, Gestational, Pre-eclampsia, AI Chatbot for Prenatal Nutrition Guidance
- Trial name
- NCT07458997
- Testing
- a culturally tailored nutrition AI chatbot for pregnant women
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Hong Kong Metropolitan University
Nurse's Role
Nurse-led Therapeutic Education Effects in Glycemic Control and Knowledge of Type 1 Diabetes Mellitus Patients Under Hospital Transition
The goal of this interventional quasiexperimental study is to learn about the influence of therapeutic education carried out by nurses in the management and knowledge of patients with T1DM.
- Trial name
- NCT05766215
- Testing
- Therapeutic Education
- Where
- Spain
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Diabetes Mellitus, Healthy Subjects
A Study Designed to Determine if the Drugs Albuterol (Salbutamol) and Fluticasone Have an Effect on the Pharmacokinetics of the Investigational Product Technosphere® Insulin Inhalation Powder in Healthy Volunteers
This study will investigate the effects of inhaled albuterol \& fluticasone on one dose of TI Inhalation Powder. A total of 12 eligible subjects will be enrolled.
- Trial name
- NCT00674050
- Testing
- Technosphere Insulin (TI) Inhalation Powder, Albuterol (Salbutamol), Fluticasone
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Mannkind Corporation
Diabetes
Single Site, Single Subject, Treatment IND With Mannkind Corporation's Technosphere Inhalation System
The purpose of this program is to allow patients with diabetes and with specific medical needs which require them to use this investigational inhaled insulin product in order to adequately manage their diabetes.
- Trial name
- NCT01459133
- Testing
- Technosphere® Insulin Inhalation System
- Where
- United States
- Sponsor
- South Orange County Endocrinology
Type 2 Diabetes Mellitus
An Investigational Drug Co-Administered With Insulin in Patients With Type 2 Diabetes (0478-065)
This is a study to evaluate the effectiveness and tolerability of an investigational drug in patients with type 2 diabetes (a specific type of diabetes) who are not currently treated with insulin.
- Trial name
- NCT00130806
- Testing
- MK0478 (muraglitazar)
- Volunteers
- 600 people
- Sponsor
- Merck Sharp & Dohme LLC
Type2 Diabetes
Effects of the Insulin Self Titration Education for Type 2 Diabetes Mellitus Patients
The purpose of the study was to evaluate the effects of an insulin self-titration education program on glycemic control, self-efficacy, and self-care behaviors in patients with type 2 diabetes.
- Trial name
- ISTE (NCT04736225)
- Testing
- Insulin Self-Titration Education Program
- Volunteers
- 120 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Diabetes Mellitus, Type 1, Type 1 Diabetes
Pharmacokinetics (PK)/ Pharmacodynamics (PD) of an Extended Wear Infusion Set for Continuous Subcutaneous Insulin Infusion (CSII) in Type 1 Diabetes Mellitus (T1DM) Patients ("PEXIS")
This study has been designed as a prospectively enrolled, randomized sequence, 2-way crossover study of device performance, tolerability and safety of an investigational insulin infusion set using a coil-reinforced soft polymer…
- Trial name
- NCT04398030
- Testing
- coil-reinforced soft polymer indwelling cannula, soft Teflon indwelling catheter
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Capillary Biomedical, Inc.