Clinical trials: Diabetes Mellitus II
Insulin Resistance
Effect of Polyphenol-rich Dark Chocolate on Insulin Sensitivity in Normal Weight and Overweight Adults
The purpose of the study is to determine the effect of polyphenol-rich dark chocolate on insulin sensitivity in normal weight and overweight adults.
- Trial name
- NCT01749020
- Testing
- Polyphenol-rich Dark chocolate
- Where
- United Kingdom
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Diabetic Foot
The Effects of BAY1193397 on Skin Capillary Blood Flow and Transcutaneous Oxygen Pressure
The purpose of the study is to analyse skin blood flow in diabetic patients. The patients receive a single dose of placebo, 1 mg BAY1193397, and 5 mg BAY1193397.
- Trial name
- NCT03128320
- Testing
- BAY1193397
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- Bayer
Diabetes Mellitus, Type II
CKD-396 Drug-drug Interaction Study(A) (CKD-396 DDI(A) P1)
The purpose of this study is to evaluate a pharmacokinetic drug interaction between lobeglitazone and sitagliptin in healthy male volunteers.
- Trial name
- NCT02824874
- Testing
- Duvie Tab. 0.5mg, Duvie Tab. 0.5mg + Januvia Tab. 100mg
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Overweight or Obese Participants Without Diabetes
A Study to Evaluate Efficacy and Safety of BGM0504 Tablets in Overweight or Obese Participants Without Diabetes
To evaluate the efficacy of BGM0504 tablets compared with placebo in reducing body weight in overweight or obese participants without diabetes after 20 weeks of treatment.
- Trial name
- NCT07658560
- Testing
- BGM0504 tablets
- Where
- China
- Volunteers
- 200 people
- Sponsor
- BrightGene Bio-Medical Technology Co., Ltd.
Type II Diabetes Mellitus With Neurological Manifestations
Effect of Physical Activity on Neurogenesis in Peripheral Diabetic Neuropathy Type-II Diabetes
Approximately 425 million people worldwide suffer from diabetes, making it a global epidemic. Diabetes consumes 12% of the global health budget, addressing the disease and its complications.
- Trial name
- NCT06101368
- Testing
- Phsical Activity, Medication
- Volunteers
- 44 people
- Sponsor
- Health Education Research Foundation (HERF)
Type 2 Diabetes, Microalbuminuria
Optimal Dose of Irbesartan for Renoprotection in Type 2 Diabetic Patients With Persistent Microalbuminuria
Aim: To evaluate the renoprotective effect as reflected by short-term changes in albuminuria of ultra high doses of irbesartan in Type 2 diabetic patients with microalbuminuria Design: A double-masked randomized cross-over trial…
- Trial name
- NCT00320879
- Testing
- irbesartan
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- Steno Diabetes Center Copenhagen
Congestive Heart Failure
Rosiglitazone to Treat Patients With Heart Failure and Glucose Intolerance or Type II Diabetes
This study will evaluate the safety and effectiveness of the drug rosiglitazone for improving heart function in patients with heart failure and glucose intolerance or type II (adult-onset) diabetes, or both.
- Trial name
- NCT00064727
- Testing
- Avandia (Rosiglitazone), Avanclia (Rosiqlitazone)
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Diabetes Mellitus, Type 2, Penile Diseases
Penile Length Restoration in Men With Diabetes Mellitus, Type II
The objective of the current study is to evaluate the efficacy of a novel penile traction device in restoring lost penile length in men with type 2 diabetes.
- Trial name
- NCT03756688
- Testing
- RestoreX PTT - 6 months, RestoreX PTT - 3 months
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Mayo Clinic
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Diabetes
A Placebo-Controlled, Randomized, Safety and Efficacy Study to Evaluate the Change in Hemoglobin A1c Levels in Type 2 Diabetic Subjects While Taking Nutralin
The purpose of this clinical research study is to evaluate the effects an investigational food product has on the blood sugar and insulin levels in individuals with diabetes.
- Trial name
- NCT01275027
- Testing
- Nutralin
- Where
- United States
- Sponsor
- Avera McKennan Hospital & University Health Center
Adult ALL, Diabete Type 2
The Physical and Mental Health of People With Type II Diabetes Mellitus.
To analyze the effects of a Pilates exercise program on physical and mental health in people with type II diabetes mellitus.
- Trial name
- NCT05711602
- Testing
- Pilates
- Where
- Spain
- Volunteers
- 104 people
- Sponsor
- University of Jaén
Type II Diabetes Mellitus
A Clinical Study to Evaluate the Safety, Tolerability, PK, PD, and Efficacy of KBP-089 in Patients With T2DM
KeyBioscience is developing KBP-089, a dual activator of both the amylin and calcitonin receptors, for the treatment of type II diabetes mellitus, using a subcutaneous injectable mode of administration.
- Trial name
- NCT03907202
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- KeyBioscience AG
Diabetes Mellitus, Insulin-Dependent
Efficacy Safety and Tolerability of Multiple Doses of Oshadi Icp (Oshadi Oral Insulin) in Patients With Type 1 Diabetes Mellitus - Phase II Clinical Study
Diabetes mellitus (DM) is a chronic disease of carbohydrate, fat, and protein metabolism caused by an absolute or relative deficiency of insulin, an anabolic hormone.
- Conditions
- Diabetes Mellitus, Insulin-Dependent, Type 1
- Trial name
- NCT01973920
- Testing
- Oshadi Icp
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Oshadi Drug Administration
Cardiovascular Disease, Diabetes Type II
Evaluation of Novartis Access; a Non-communicable Disease (NCD) Access Initiative
Countries throughout the world are facing a growing non-communicable disease (NCD) burden. In developing countries, medicines to treat NCDs are often difficult to access or too expensive for many households.
- Conditions
- Cardiovascular Disease, Diabetes Type II, Breast Cancer, Asthma
- Trial name
- NCT02773095
- Testing
- Novartis Access
- Volunteers
- 966 people
- Sponsor
- Boston University
Type II Diabetes
Clinical Trial for PB-119 in Healthy Subjects (Phase I)
GLP-1 analogues have been widely used because of their unique advantages (no risk of hypoglycemia) due to their glucose dependent mechanism.
- Trial name
- NCT02084251
- Testing
- PB-119
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- PegBio Co., Ltd.
Type II Diabetes Mellitus
Application of Magnetic Fields as Adjunctive Treatment for Type II Diabetes
The purpose of this study is to see if using a device called the Resonator, that puts out a very low electromagnetic field, effects blood glucose and A1c levels in people with Type 2 Diabetes.
- Trial name
- NCT00863954
- Testing
- Resonator Device
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- pico-tesla Magnetic Therapies, LLC
Chronic Obstructive Pulmonary Disease, Type II Diabetes
Mobile Unit Screening of Pathologies Associated With Chronic Diseases - Feasibility
The main objective of this study is to assess the feasibility of standardized screening for comorbidities among patients with one or more of three chronic diseases (diabetes, COPD, atherosclerosis) by a mobile unit at times and…
- Conditions
- Chronic Obstructive Pulmonary Disease, Type II Diabetes, Atherosclerosis
- Trial name
- DéProPAss (NCT02214056)
- Testing
- Patient recruitment, Mobile team exam
- Where
- 13 sites in France
- Volunteers
- 27 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Diabetes Mellitus
Efficacy of TAK-559 in Treating Subjects With Type 2 Diabetes Mellitus
The purpose of this study was to determine the safety and efficacy of TAK-559, once daily (QD), in Type 2 Diabetes subjects.
- Trial name
- NCT00763022
- Testing
- TAK-559
- Volunteers
- 302 people
- Sponsor
- Takeda
Type 2 Diabetes
Glycaemic Control of Weekly LAPS-Exendin Versus Placebo in Subjects of Type 2 Diabetes
The purpose of this study is to determine the optimal dose or doses of HM11260C, when administered once a week under the skin, to improve the control of blood sugar levels in patients with early-stage type 2 diabetes mellitus…
- Trial name
- NCT02057172
- Testing
- HM11260C, liraglutide
- Where
- United States
- Volunteers
- 254 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Diabetic Retinopathy, Diabetes Complications
Study Evaluating Efficacy and Safety of PF-04523655 Versus Laser in Subjects With Diabetic Macular Edema
To evaluate the effectiveness of study drug in improving visual acuity compared to laser treatment in the patients with diabetic macular edema
- Trial name
- DEGAS (NCT00701181)
- Testing
- Laser Treatment, PF-04523655 high, PF-04523655 middle
- Where
- 53 sites in United States, Denmark and 6 more
- Volunteers
- 184 people
- Sponsor
- Quark Pharmaceuticals