Clinical trials: Diabetes Mellitus II
Diabetes Mellitus, Type 2
A Study in Patients With Type 2 Diabetes
The study is designed to see if once daily oral dosing of LY2608204 will help control diabetes as measured by the glycosylated fraction of hemoglobin A (HbA1c) level.
- Trial name
- NCT01408095
- Testing
- LY2608204, Glimepiride
- Where
- 38 sites in United States, Austria and 5 more
- Volunteers
- 240 people
- Sponsor
- Eli Lilly and Company
Type 2 Diabetes Mellitus, Diabetic Kidney Disease
Efficacy and Safety of Jinshuibao Capsule on Diabetic Kidney Disease
The purpose of this study is to investigate the therapeutic effect and safety of Jinshuibao Capsule on diabetic kidney disease in T2DM patients.
- Trial name
- NCT03164785
- Testing
- Jinshuibao Capsule
- Where
- China
- Volunteers
- 202 people
- Sponsor
- Second Xiangya Hospital of Central South University
NSCLC Stage II, NSCLC Stage III
Efficacy of Anti-CTLA-4 Antibody Combined With Sintilimab and Chemotherapy as Neoadjuvant Therapy for Resectable Stage II-III Non-Small Cell Lung Cancer
This study aims to evaluate the major pathologic response (MPR) rate of neoadjuvant therapy with sintilimab (PD-1 inhibitor) + IBI310 (anti-CTLA-4 antibody) + chemotherapy, and to assess the efficacy of this treatment strategy in…
- Trial name
- NCT07410975
- Testing
- sintilimab+IBI310+chemotherapy
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Type II Diabetes Mellitus
A Clinical Trial to Evaluate the Food Effect of CKD-378
A clinical trial to evaluate the food effect of CKD-378
- Trial name
- NCT06386328
- Testing
- CKD-378, QD, PO
- Where
- South Korea
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Diabetes Mellitus, Type 2
A New Oral Treatment For Type II Diabetes Mellitus
This is a 24-week study investigating the safety and efficacy of several dosages of a potential new oral medicine for Type II diabetes mellitus.
- Trial name
- NCT00111800
- Testing
- DEN 2.5 mg, DEN 7.5 mg, DEN 15 mg
- Where
- 109 sites in United States, Canada and 8 more
- Volunteers
- 375 people
- Sponsor
- GlaxoSmithKline
Neoplasms, Immunotherapy
IMMUNO-FIT Observational Study
This observational study will investigate how immunotherapy affects physical fitness, quality of life, and treatment tolerance in adults with solid cancers.
- Conditions
- Neoplasms, Immunotherapy, Physical Fitness, Quality of Life
- Trial name
- NCT07354971
- Testing
- Observational Study - No Study Intervention
- Where
- United Kingdom
- Volunteers
- 67 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Diabetes Mellitus, Type 2, Diabetes
Dietary Approaches to Stop Hypertension for Diabetes
The objective of the DASH4D trial is to determine the effects, alone and combined, of (a) the DASH4D diet (a DASH-style diet modified for people with diabetes) vs.
- Conditions
- Diabetes Mellitus, Type 2, Diabetes, Diabetes type2, Type2 Diabetes
- Trial name
- DASH4D (NCT04286555)
- Testing
- DASH4D diet, comparison diet, higher sodium
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Johns Hopkins University
Diabetes Mellitus Type II
20 Week Bridging Study in Type II DM
A multicenter, non-comparative, one arm, open, phase III study to evaluate the efficacy and safety of insulin glargine on subjects with Type 2 Diabetes Mellitus
- Trial name
- NCT00563225
- Testing
- Insulin Glargine
- Volunteers
- 90 people
- Sponsor
- Sanofi
Type 2 Diabetes Mellitus
An Exploratory Study of DS-8500a on Beta Cell Function Using Hyperglycemic Clamp
The objective of the study is to evaluate change in insulin secretory capacity in patients with type 2 diabetes mellitus as determined by hyperglycemic clamp after a 28-day oral administration of DS-8500a at 75 mg in a…
- Trial name
- NCT02669732
- Testing
- DS-8500a
- Where
- Japan
- Volunteers
- 21 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Diabetes Mellitus, Diabetes Mellitus, Type 1
Mesenchymal Stem Cells Transplantation in Newly Diagnosed Type-1 Diabetes Patients
Study Objects: Diabetes is an autoimmune disease which is mainly caused an immune reaction to beta cells in the pancreas. In this study, mesenchymal stem cells will be used for immune response modulation and improving…
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 1, Diabetes Mellitus, Insulin-Dependent
- Trial name
- MSCTXT1DM (NCT04078308)
- Testing
- Intravenous Injection of autologous mesenchymal stem cells
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Royan Institute
Type II Diabetes Mellitus
Rosiglitazone and Exercise in Patients With Type 2 Diabetes Mellitus
The aim of the present study is to investigate the influence of systemic exercise, rosiglitazone administration and combined pharmaceutical and lifestyle intervention on cardiovascular risk factors
- Trial name
- NCT00306176
- Testing
- Rosiglitazone
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Type II Diabetes Mellitus
Evaluate the Side Effects and Benefits of RAS 130 With or Without Diet and Exercise in Type II Diabetes Mellitus
Rationale: RAS 130 is an anti-diabetic agent used to lower the blood glucose level in Type II Diabetes mellitus (non-insulin-dependent diabetes) patients with proper diet and exercise.
- Trial name
- ASI-DMII (NCT00737152)
- Testing
- RAS 130 with diet and exercise
- Where
- 5 sites in United States, India
- Volunteers
- 460 people
- Sponsor
- American Scitech International
Cardiovascular Benefits of Zingiber Officinale Roscoe in Patients With Type 2 Diabetes Mellitus Before and After 6 Weeks of add-on Therapy
The Cardiovascular Effects of Ginger (Zingiber Officinale) in Patients With Type II Diabetes Mellitus
The aim of the study was the evaluation of cardiovascular benefits of Zingiber officinale Roscoe in patients with type 2 diabetes mellitus before and after 6 weeks of add-on therapy.
- Trial name
- GINOFF1 (NCT04222738)
- Testing
- GINOFF1
- Where
- Cameroon
- Volunteers
- 21 people
- Sponsor
- Yaounde Central Hospital
Obesity, Type II Diabetes Mellitus
Yellow Pea Protein and Fibre and Short Term Food Intake
It is hypothesized that yellow pea protein and fiber will reduce short-term food intake, subjective appetite and glycemic response.
- Conditions
- Obesity, Type II Diabetes Mellitus, Metabolic Syndrome
- Trial name
- NCT01255085
- Testing
- yellow pea protein, yellow pea fiber, Control Tomato Soup
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Diabetic Nephropathy, Nephrotic Syndrome
Adrenocorticotropic Hormone (ACTH) Treatment of Nephrotic Range Proteinuria in Diabetic Nephropathy (NRDN)
This is a prospective open labeled trial examining the efficacy of ACTHar Gel (porcine ACTH) on the level of proteinuria in patients with diabetic nephropathy and nephrotic range proteinuria.
- Trial name
- ACTH-NRDN (NCT01028287)
- Testing
- ACTH
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Southeast Renal Research Institute
Diabetes Mellitus, Type II
Effect of SLC30A8 rs13266634 Genetic Polymorphism on Zinc Supplementation and Glycemic Control in Egyptian Patients With Type 2 Diabetes Mellitus
Study whether SLC30A8 rs13266634 polymorphism is associated with type 2 diabetes mellitus (T2DM) susceptibility in Egyptian patients and study effect of Zn supplementation on glycemic control in patients with type 2 diabetes
- Trial name
- SLC30A8 (NCT03112382)
- Testing
- zinc supplement plus vitamin A and E, vitamin A and E
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diabetes Mellitus
Efficacy of Alogliptin and Pioglitazone in Subjects With Type 2 Diabetes Mellitus
The purpose of the study is to compare the effect of adding alogliptin, once daily (QD), to the ongoing treatment regimen of pioglitazone HCl and metformin in patients with inadequate glycemic control.
- Trial name
- NCT00432276
- Testing
- Alogliptin, Pioglitazone, Metformin
- Where
- 86 sites in United States
- Volunteers
- 803 people
- Sponsor
- Takeda
Complications of Diabetes Mellitus
Clinical Study on Metabolic Surgery Compared to the Best Clinical Treatment in Patients With Type 2 Diabetes Mellitus
This is a prospective, open, randomized study involving 100 patients with microvascular complications of type 2 diabetes mellitus and obesity, who will undergo gastric bypass (Roux-en-Y gastric bypass ARM A) or receive best…
- Trial name
- MOMS (NCT01821508)
- Testing
- Clinical Treatment, Roux-En-Y gastric bypass surgery
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Hospital Alemão Oswaldo Cruz
Diabetes Mellitus, Type 2
The Value of Adding Group Education (DESMOND Method) to the Standard Primary Care Education Practices in Changing Glycemic Control and Self-care Practices in Adults With Type II Diabetes Mellitus: A Randomized Controlled Intervention Study.
The goal of this clinical trial is to assess the outcome of delivering the health education in a group format using the DESMOND program compared to the standard health education in newly diagnosed adults with type 2 diabetes…
- Trial name
- NCT06513468
- Testing
- Group education session by DESMOND Program
- Where
- Qatar
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Primary Health Care Corporation, Qatar
Type 2 Diabetes
Dog-rose, Cranberry Leaves, Cranberry Berries, Alfalfa, Fenugreek, Lemon Beebrush, Urtica and Sumac in Diabetes Mellitus
This study investigates the safety and combined effect of Cranberry leaves, Cranberry Berries, Alfalfa, Fenugreek, Lemon Beebrush, Urtica, Dog-rose, and Sumac on improving the glycemic profile of patients with type 2 diabetes…
- Trial name
- NCT05700513
- Testing
- Capsules containing the combination products
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Tabriz University of Medical Sciences