Clinical trials: Diet, Sodium-Restricted
Safety
First in Human Single Ascending Dose Study of MOR107
This is the first in human study of MOR107. It is a 2 part, single centre, double-blind, randomised, placebo-controlled study in healthy male subjects.
- Trial name
- NCT03067363
- Testing
- MOR107, Low sodium diet
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Alan Richardson
Essential Hypertension and Healthy Controls
The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Essential Hypertension
The aim of the study is to test the following hypotheses: that the function and/or regulation of AQP2 and/or ENaC in the principal cells is abnormal in essential hypertension.
- Trial name
- NCT00345124
- Testing
- high sodium diet, Low Sodium Diet
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
Hypertension
Effects of Low Salt Diet Versus High Salt Diet on Blood Pressure
High blood pressure is a global public health problem in developed and developing countries including Pakistan. Various studies conducted around the world have linked salt intake to variation in the blood pressure.However…
- Trial name
- NCT00330356
- Testing
- Low Salt Diet versus High salt diet
- Where
- Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Obstructive Sleep Apnea
Sodium-Restricted Diet and Diuretic in the Treatment of Severe Sleep Apnea
This study evaluates the intervention of the 1) sodium-restricted diet, or 2) diuretic, or 3) placebo pill in the treatment of obstructive sleep apnea in adults.
- Trial name
- DESALT (NCT01945801)
- Testing
- Lasilactone, Sodium-Restricted Diet
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Declination of Glomerular Infiltration Rate in Chronic Kidney Disease Population
Effect of Intensive Low Sodium Restriction on Glomerular Infiltration Rate in Chronic Kidney Disease
Introduction : Due to Chronic kidney disease is a public health problem, which is important increased in both developed and developing countries .
- Trial name
- NCT02519894
- Testing
- Dietary Scanning Calculator
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- PANTHITA SORNHIRAN
Blood Pressure, Hypertension
A Community Health Worker-Led LSSS Intervention in Bangladesh
The sodium found in salt is a powerful cause of high blood pressure, and most sodium ingested by humans is from their diet. High blood pressure is known to cause heart attacks and strokes, so various public health programs have…
- Trial name
- NCT05425030
- Testing
- Low-Sodium Salt Substitute, Information/Education
- Where
- Bangladesh
- Volunteers
- 618 people, healthy volunteers welcome
- Sponsor
- Stanford University
ESRD
Sodium-restricted Diets and Symptoms in End Stage Renal Disease: An RCT
Dietary sodium intake independently increases the risk of mortality in end stage renal disease (ESRD). It plays a significant role in hypertension, hypervolemia, and left ventricular hypertrophy (LVH), and blunts the…
- Trial name
- NCT02778516
- Testing
- Sodium Restriction
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Chronic Renal Failure, Hypertension
Low Sodium Dialysate and Ambulatory Blood Pressure Measurement Parameters
End stage renal disease (ESRD) is related with increased cardiovascular mortality and morbidity. Hypertension (HT) is an important risk factor for cardiovascular disorder among hemodialysis (HD) patients.
- Trial name
- NCT02621450
- Testing
- standart dialysis, low sodium dialysis
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Prehypertension, Hypertension
Combined Dietary Education of Low Sodium and High Potassium Consumption
Reduction in sodium consumption is important approach in public health care. In general population, reduction of sodium intake can reduce the future development of hypertension and cardiovascular event.
- Trial name
- NCT01914224
- Testing
- dietary education of low sodium and high potassium consumption, dietary education of low sodium consumption only
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- DongGuk University
Polycystic Kidney, Autosomal Dominant
The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Autosomal Dominant Polycystic Kidney Disease
The aim of the study is to test the following hypotheses: 1. that the function and/or regulation of AQP2 and /or ENaC in the principal cells is abnormal in autosomal dominant polycystic kidney disease. 2.
- Trial name
- NCT00410007
- Testing
- High Sodium Diet, Low Sodium Diet, Hypertonic saline infusion
- Where
- Denmark
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Carolina Cannillo
Hypertension, Elevated Blood Pressure
Groceries for Residents of Southeastern USA to Stop Hypertension
GoFreshSE is a randomized control trial, testing the effects of a home-delivered, dietitian-assisted, DASH-patterned grocery intervention on blood pressure in adults with high blood pressure in Florida, Georgia, and Tennessee.
- Conditions
- Hypertension, Elevated Blood Pressure, Cardiovascular Diseases, Dietary Intervention
- Trial name
- GoFreshSE (NCT06891911)
- Testing
- Dietitian-Assisted DASH groceries, Self-directed shopping
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Elevated Blood Pressure
'Low-salt' Bread as a Means of Reducing Dietary Salt and Lowering Blood Pressure
In the context of public health, reformulation of bread in terms of salt content remains an important measure to help achieve a reduction in salt intake in the population.
- Trial name
- Saltbreads (NCT04003597)
- Testing
- Usual-salt diet, Reduced-salt diet
- Where
- Ireland
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University College Cork
Postural Tachycardia Syndrome (POTS)
Effect of Dietary Sodium Intake on Vascular Endothelium
The investigators will test the hypothesis that markers of vascular endothelial dysfunction will be exaggerated acutely with an extreme high sodium diet compared to an extreme low-sodium diet.
- Trial name
- NCT01550315
- Testing
- Pulsitile Arterial Tonometry (PAT) Protocol, Calf Blood Flow in Reactive Hyperemia (CBF-RH), Evaluation of Forearm-Mediated Dilation
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Refeeding Syndrome
The Effect of a Diet Based on Low Sodium and Slowly Absorbed Carbohydrates on the Incidence of Refeeding Syndrome in Patients With Head and Neck Cancer
The study is based on a master thesis which showed that 72% of patients with head and neck cancer admitted to a Danish hospital (Rigshospitalet, Copenhagen) developed refeeding syndrome after admission.
- Trial name
- NCT01845922
- Testing
- Low sodium diet
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Hypertensive Disease
Activating Media for Salt Reduction
Mass media plays more and more important role in health education, especially in some chronic diseases which related closely with the behavior and habits.
- Trial name
- NCT03074851
- Testing
- low sodium salt, informational intervention
- Where
- China
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- The George Institute for Global Health, China
Sodium Excess, Cardiovascular Risk Factor
A Short, Animated Storytelling Video to Increase Knowledge About Sodium Intake as a Cardiovascular Risk Factor
This study will evaluate the effect of a short, animated storytelling intervention video on sodium intake as a major risk factor for cardiovascular disease on immediate and medium-term retention of knowledge about the risks of…
- Conditions
- Sodium Excess, Cardiovascular Risk Factor, Education Entertainment Intervention, Short, Animated Storytelling
- Trial name
- NCT05735457
- Testing
- A short, animated storytelling video on dietary sodium
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
Oligohydramnios
Low Sodium Diet in Oligohydramnios Assigned for Conservative Management
The investigators want to examine whether low salt diet can increase the amniotic fluid index in patients diagnosed with oligohydramnios and assigned for conservative management. A randomized controlled trial
- Trial name
- NCT03815968
- Testing
- low sodium diet
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Cardiovascular Diseases, Obesity
Low Sodium Diet and Behavioral Intervention for Reversing Arterial Stiffening in Overweight Individuals
Obese individuals are at risk for developing cardiovascular disease (CVD). Increasing physical activity, losing weight, and reducing sodium intake may reverse arterial stiffness and blood vessel damage that is linked to obesity.
- Trial name
- SAVE (NCT00366990)
- Testing
- Low Sodium Diet, Regular Sodium Intake
- Where
- United States
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Albuminuria
Effects of Intensive Low-Salt Diet Education by Mobile Application on Albuminuria
Albuminuria is a known risk factor for cardiovascular disease (CVD), chronic kidney disease (CKD) progression, all cause mortality.
- Trial name
- NCT03396328
- Testing
- conventional low salt education, Intensive low salt dietary education by smartphone application
- Where
- South Korea
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Heart Failure
Effects of Family Sodium Watcher Program on Outcomes in Heart Failure Patient-Family Caregiver Dyads
The Family Sodium Watcher program in this study is designed to improve adherence to a sodium restricted diet in patients with HF using strategies that educate both patients and family caregivers about sodium monitoring and that…
- Trial name
- FAMSWAP (NCT03560206)
- Testing
- Family SWaP intervention, usual care
- Where
- United States
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Misook L. Chung