Clinical trials: Diet, Sodium-Restricted
Polycystic Kidney, Autosomal Dominant
The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Autosomal Dominant Polycystic Kidney Disease
The aim of the study is to test the following hypotheses: 1. that the function and/or regulation of AQP2 and /or ENaC in the principal cells is abnormal in autosomal dominant polycystic kidney disease. 2.
- Trial name
- NCT00410007
- Testing
- High Sodium Diet, Low Sodium Diet, Hypertonic saline infusion
- Where
- Denmark
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Carolina Cannillo
Hypertension
Effect of High- and Low-sodium Intake on the Pharmacokinetics and Pharmacodynamic Effects of Fimasartan
It has been known that the blood pressure lowering effect of angiotensin receptor antagonists (ARBs) and angiotensin converting enzyme (ACE) inhibitors is impaired in patients on high sodium intake.
- Trial name
- NCT02147704
- Testing
- High-sodium diet, low-sodium diet
- Where
- South Korea
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- DongGuk University
Healthy
Effects of Sodium Intake on (PK/PD) Relationship of a Single Dose of a Renin Angiotensin System-Blocker
The impact of sodium intake on plasma drug concentrations has previously been reported in the literature for verapamil and quinidine but, to the investigators' knowledge, never with renin-angiotensin system blockers such as AT1R…
- Trial name
- NCT00310778
- Testing
- high sodium diet, low sodium diet, ramipril 10 mg
- Where
- France
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Refeeding Syndrome
The Effect of a Diet Based on Low Sodium and Slowly Absorbed Carbohydrates on the Incidence of Refeeding Syndrome in Patients With Head and Neck Cancer
The study is based on a master thesis which showed that 72% of patients with head and neck cancer admitted to a Danish hospital (Rigshospitalet, Copenhagen) developed refeeding syndrome after admission.
- Trial name
- NCT01845922
- Testing
- Low sodium diet
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Urinary Stones, Hypertension
The Links Between Water and Salt Intake, Body Weight, Hypertension and Kidney Stones: a Difficult Puzzle
Nephrolithiasis is a disease that strikes roughly 10% of the Italian population and its incidence in industrialized countries is on the increase.
- Conditions
- Urinary Stones, Hypertension, Overweight, Obesity
- Trial name
- NCT01100580
- Testing
- low salt diet, water therapy
- Where
- Italy
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Parma
Obstructive Sleep Apnea
Sodium-Restricted Diet and Diuretic in the Treatment of Severe Sleep Apnea
This study evaluates the intervention of the 1) sodium-restricted diet, or 2) diuretic, or 3) placebo pill in the treatment of obstructive sleep apnea in adults.
- Trial name
- DESALT (NCT01945801)
- Testing
- Lasilactone, Sodium-Restricted Diet
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hypertension
Efficacy of Dietary Sodium Restriction of Improving Vascular Endothelial Function in Middle Aged and Older Adults
The investigators hypothesize that reducing salt in the diet will improve the function of blood vessels in middle aged and older adults with moderately elevated systolic blood pressure, by increasing the amount of BH4 and nitric…
- Trial name
- NCT01566084
- Testing
- Slow sodium tablets
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Oligohydramnios
Low Sodium Diet in Oligohydramnios Assigned for Conservative Management
The investigators want to examine whether low salt diet can increase the amniotic fluid index in patients diagnosed with oligohydramnios and assigned for conservative management. A randomized controlled trial
- Trial name
- NCT03815968
- Testing
- low sodium diet
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Cardiovascular Diseases, Obesity
Low Sodium Diet and Behavioral Intervention for Reversing Arterial Stiffening in Overweight Individuals
Obese individuals are at risk for developing cardiovascular disease (CVD). Increasing physical activity, losing weight, and reducing sodium intake may reverse arterial stiffness and blood vessel damage that is linked to obesity.
- Trial name
- SAVE (NCT00366990)
- Testing
- Low Sodium Diet, Regular Sodium Intake
- Where
- United States
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Satiety Response, Carbohydrate Metabolism
Low Sodium Neapolitan Pizza Prepared With Seawater: Nutritional Properties, Sensory Characteristics, Metabolic Effects
Seawater is rich in minerals which may help confer good palatability to foods, favouring the use of smaller amounts of salt, a recognized measure of cardiovascular prevention.
- Conditions
- Satiety Response, Carbohydrate Metabolism, Sodium Retention
- Trial name
- NCT04629742
- Testing
- Seawater Pizza, Standard pizza
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Federico II University
Idiopathic Intracranial Hypertension
Idiopathic Intracranial Hypertension Treatment Trial
Idiopathic intracranial hypertension (IIH), also called pseudotumor cerebri, is a disorder of elevated intracranial pressure of unknown cause [Corbett, et al., 1982; Wall, et al., 1991].
- Trial name
- IIHTT (NCT01003639)
- Testing
- Acetazolamide, Formal weight loss counselling program
- Where
- 41 sites in United States, Canada
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Safety
First in Human Single Ascending Dose Study of MOR107
This is the first in human study of MOR107. It is a 2 part, single centre, double-blind, randomised, placebo-controlled study in healthy male subjects.
- Trial name
- NCT03067363
- Testing
- MOR107, Low sodium diet
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Alan Richardson
Postural Tachycardia Syndrome (POTS)
Effect of Dietary Sodium Intake on Vascular Endothelium
The investigators will test the hypothesis that markers of vascular endothelial dysfunction will be exaggerated acutely with an extreme high sodium diet compared to an extreme low-sodium diet.
- Trial name
- NCT01550315
- Testing
- Pulsitile Arterial Tonometry (PAT) Protocol, Calf Blood Flow in Reactive Hyperemia (CBF-RH), Evaluation of Forearm-Mediated Dilation
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center