Clinical trials: Dietary Fats
Leukemia, Lymphocytic, Acute, Leukemia, Myeloid, Acute
High- Fiber/ Low-fat Diet for Prevention of Recurrent Clostridioides Difficile Infection in Oncology
The primary objective of the study is to determine whether dietary intervention to increase fiber and decrease fat reduces C. difficile infection recurrence in a cohort of oncology patients.
- Conditions
- Leukemia, Lymphocytic, Acute, Leukemia, Myeloid, Acute, Lymphoma, Clostridium Difficile Infection
- Trial name
- NCT04940468
- Testing
- Diet Intervention
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- University of Colorado, Denver
Hepatic Fat Content
Monitoring of Hepatic Fat Metabolism Using Magnetic Resonance Methods
The first primary research objective of the study is to determine whether high-fat load (150 g of fat) induces increase in hepatic fat content (HFC) three and six hours after meal in insulin-sensitive subjects with normal HFC…
- Trial name
- NCT03680248
- Testing
- Fat, Fasting, Fat+Glucose
- Where
- Czechia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Institute for Clinical and Experimental Medicine
Insulin Resistance
Pilot Study to Test Dietary Fat Delivery
The average American diet consumed by a significant proportion of the adult population, supplies excessive calories and large amounts of saturated fat.
- Trial name
- NCT02101996
- Testing
- high-fat diet
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Body Weight Changes
Effect of Dietary Fat When Eaten With Fructose Versus Glucose
This study is designed to test the effects on liver fat of varying fat intake in the presence of fructose or glucose. We hypothesize that higher dietary fat when eaten with fructose as compared to glucose will increase the amount…
- Trial name
- Fructose (NCT01061346)
- Testing
- 40% Fat Diet, 20% Fructose Beverage, 20% Glucose Beverage
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Dietary Fats, Pharmacokinetics
The Effect of Food (High Fat and Low Fat Breakfast) on the Pharmacokinetics of Regorafenib
An open label, three way crossover study to determine the effect of a high fat breakfast or a low fat breakfast on the pharmacokinetics of a single dose of regorafenib.
- Trial name
- NCT01002378
- Testing
- Regorafenib (Stivarga, BAY73-4506)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bayer
Liver Fat
Liver, Diet and Genetic Background
PNPLA3 rs738409 (I148M) variant is associated with hepatic liver accumulation and chronic liver diseases including non-alcoholic fatty liver disease.
- Trial name
- LIDIGE (NCT04644887)
- Testing
- Dietary intervention: Healthy diet, Dietary intervention: Control diet
- Where
- Finland
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Healthy, Healthy Volunteer
Avocado and Postprandial Responses
The purpose of this study is to see how adding avocado to a breakfast meal affects blood sugar control and signals of hunger and fullness after eating.
- Conditions
- Healthy, Healthy Volunteer, Healthy Volunteers, Healthy Adult
- Trial name
- NCT06818032
- Testing
- Negative control, Avocado, Fat and fiber addition
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Vermont Medical Center
Type 1 Diabetes Mellitus, Glycemic Variability
Impact of Dietary Fat and Menstrual Cycle Phases in Type 1 Diabetes
This clinical trial aims to evaluate how variations in dietary fat content and hormonal status influence postprandial glycemic response in individuals with type 1 diabetes (T1D), with a special focus on women.
- Conditions
- Type 1 Diabetes Mellitus, Glycemic Variability, Sex Characteristics, Menstrual Cycle
- Trial name
- DIABETEXX/3 (NCT07278063)
- Testing
- Low Fat Mixed Meal, High Fat Mixed Meal
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Obesity
Dietary Lipids, Energy Expenditure and Obesity Biomarkers
The purpose of this study is to determine whether the modulation of dietary lipids are effective in the treatment of obesity and comorbidities.
- Trial name
- NCT02656940
- Testing
- Group 1 - diet rich in n-3 and n-6 PUFA, Group 2 - diet rich in MUFA
- Volunteers
- 32 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Healthy Conditions
Diet Induced Intestinal Mucosal Adaptation
Human beings are 'omnivores' meaning that all principal components of food (i.e. the macronutrients: carbohydrates, fat, proteins) can be assimilated by the gastrointestinal tract.
- Trial name
- NCT02088853
- Testing
- high fat diet (hfd), then high carbohydrate diet, high carbohydrate diet, then high fat diet
- Where
- Sweden
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Healthy
Effect of Dietary Fat Type in Combination With High Protein on Plasma Homocysteine Levels
In this study, the investigators address the research question of whether palm olein will have a positive influence on plasma total homocysteine levels in human volunteers provided with high-protein diets formulated from common…
- Trial name
- NCT00941837
- Testing
- Olive Oil, Palm Olein Oil, Coconut Oil
- Where
- Malaysia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Myocardial Infarction
The Heart Institute of Spokane Diet Study
The purpose of this study is to determine whether a Mediterranean style diet, enriched in monounsaturated and omega-3 fats, is superior to the American Heart Association Step 2 diet, a traditional low fat diet, for improving…
- Trial name
- NCT00269425
- Testing
- American Heart Association Step 2 diet, Mediterranean diet
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Providence Health & Services
Small Intestine
Healthy Fat, Happy Microbiome (TAPIR), Proof-of-Concept Study
Rationale: The role of dietary lipids in host-microbiome research has for a long time been overlooked; as high lipid intake has been recently indicated to have the most pronounced effect on the small intestinal microbiome…
- Trial name
- TAPIR (NCT06064266)
- Testing
- plant-based mild ketogenic controlled diet, high-fat shake
- Where
- Netherlands
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Endotoxemia
The Role of Dietary Fat on Postprandial Endotoxemia in Healthy Adults
The purpose of this study was to determine the effect of different dietary fats (saturated or unsaturated) on postprandial endotoxemia and systemic low grade acute inflammation.
- Trial name
- NCT02521779
- Testing
- Low-fat Treatment Meal, Saturated-fat Treatment Meal, N-3 fat Treatment Meal
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Cardiovascular Diseases
Study Into Genetic Influence on Cholesterol Response to Dietary Fat
Cardiovascular disease (CVD) is recognised as one of the main causes of death in the western world. LDL- cholesterol ('bad' cholesterol) and other lipids (fats) are important CVD risk factors.
- Trial name
- Satgene (NCT01384032)
- Testing
- Low fat diet, Hgih saturated fat diet, High saturated fat diet
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Reading
Phosphorus Metabolism Disorders
Dietary Phosphate and Serum Phosphorus
Overall study design is to review National Health and Nutrition Examination Survey (NHANES) data 1999-2008 for nutrition risk according to kidney function.
- Trial name
- NCT02435017
- Volunteers
- 7,895 people, healthy volunteers welcome
- Sponsor
- Linda W. Moore
NAFLD
Understanding the Role of Dietary Fatty Acids on Liver Fat Metabolism in Humans
High levels of fatty substances in the blood increase the risk of developing heart disease. Investigators know a lot about one of these fatty substances, cholesterol.
- Trial name
- NCT01936779
- Testing
- Dietary supplement: fatty acid
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Obesity
Obesity, Physical Inactivity or Dietary Fat ?
Obesity is the consequence of a chronic disequilibrium of fat balance. Genetic factors determine predisposition to obesity, but the most often mentioned idea is that environmental factors, such as a high-fat diet and a sedentary…
- Trial name
- NCT00434265
- Testing
- Physical training
- Where
- 2 sites in France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Strasbourg, France
Hypertriglyceridemia
Metabolic Effects of Egg Protein and Unsaturated Fat Intakes in Subjects With Hypertriglyceridemia
The goal of this study is to evaluate the effects of replacing some refined starches and added sugars with a combination of egg protein and unsaturated fatty acids on markers of cardiometabolic health in men and women with…
- Trial name
- NCT02924558
- Testing
- Egg protein/unsaturated fatty acid, Control
- Volunteers
- 28 people
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Adenocarcinoma of the Prostate, Hormone-resistant Prostate Cancer
Dietary Fat Levels and Abiraterone Acetate Uptake in Patients With Metastatic Hormone-Resistant Prostate Cancer
This randomized pilot phase I trial studies the side effects of dietary fat levels and abiraterone acetate uptake in patients with metastatic hormone-resistant prostate cancer.
- Conditions
- Adenocarcinoma of the Prostate, Hormone-resistant Prostate Cancer, Recurrent Prostate Cancer, Stage IV Prostate Cancer
- Trial name
- NCT01913015
- Testing
- abiraterone acetate, dietary intervention, pharmacological study
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- OHSU Knight Cancer Institute