Clinical trials: Digital Tomosynthesis
Recall Rate, Cancer Detection Rate
Tomosynthesis in the Oslo Breast Cancer Screening Program
The Digital Breast Tomosynthesis (DBT) in the Oslo Mammography Screening Program will include women aged 50 to 69 years invited to the population-based mammography-screening program.
- Conditions
- Recall Rate, Cancer Detection Rate, False Positive Rate, Positive Predictive Value
- Trial name
- DBT (NCT01248546)
- Testing
- Digital breast tomosynthesis
- Where
- Norway
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Breast Cancer, Screening
Artificial Intelligence in Breast Cancer Screening Programs
The use of artificial intelligence software in breast screening (Transpara®) makes it possible to identify studies with a very low probability of cancer.
- Trial name
- AITIC (NCT04949776)
- Testing
- Mammograms
- Where
- Spain
- Volunteers
- 31,301 people, healthy volunteers welcome
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Mammographic Breast Density
Breast Density Measurements in Digital Mammography and Breast Tomosynthesis Systems of Different Pixel Size
Breast cancer (BC) is the most frequently diagnosed cancer in women worldwide. The cause of developing BC is currently unknown. However, there are several risk factors, such as volumetric breast density (VBD), which have been…
- Trial name
- NCT04127175
- Testing
- Volpara
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Corporacion Parc Tauli
Breast Neoplasms
The Digital Breast Tomosynthesis Trial in Bergen
Compare synthetic mammography+digital breast tomosynthesis (SM+DBT) with digital mammography (DM) as a screening tool for women aged 50-69 years, invited to participate in the Norwegian Breast Cancer Screening Program at the…
- Trial name
- TOBE (NCT02835625)
- Testing
- Synthetic Mammography + Digital Breast Tomosynthesis, Digital mammography
- Where
- 2 sites in Norway
- Volunteers
- 29,453 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Breast Carcinoma
Molecular Breast Imaging and Digital Breast Tomosynthesis in Screening Patients With Dense Breast Tissue
This study compares molecular breast imaging (MBI) and digital breast tomosynthesis (DBT) in screening patients with dense breast tissue. Breast imaging may help doctors find breast cancer sooner, when it may be easier to treat.
- Trial name
- NCT03220893
- Testing
- Digital Breast Tomosynthesis (DBT), Scintimammography
- Where
- 5 sites in United States
- Volunteers
- 3,023 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Digital Breast Tomosynthesis
Value of Digital Breast Tomosynthesis in Breast Lesions
The aim of the study is to evaluate the added value of digital breast tomosynthesis (DBT) in the characterization of breast lesions.
- Trial name
- NCT06687902
- Testing
- Digital breast tomosynthesis
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Breast Cancer Screening
Breast Cancer Screening: Digital Breast Tomosynthesis Versus Digital 2D Mammography
This study is a randomized, multicenter, multivendor, controlled, diagnostic superiority trial to compare digital breast tomosynthesis plus synthesized 2D mammograms (DBT+s2D) versus standard 2D full-field digital mammography…
- Trial name
- TOSYMA (NCT03377036)
- Testing
- DBT+s2D, 2D-FFDM
- Where
- 21 sites in Germany
- Volunteers
- 99,689 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Breast Neoplasms
Comparison of Full-Field Digital Mammography With Digital Breast Tomography for Screening Call-Back Rates
This multicenter trial using Hologic digital mammography units will evaluate the specificity of 2-D full field digital mammography (FFDM) versus a combination of 2-D and 3-D tomosynthesis imaging in breast cancer screening.
- Trial name
- NCT01236781
- Testing
- Screening Tomosynthesis, Diagnostic Tomosynthesis
- Where
- 2 sites in United States
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- American College of Radiology
Breast Cancer
Innovation in Mammography: Tomosynthesis Pathways
The study aims at evaluating the introduction of tomosynthesis in mammography screening, analyzing the benefits, disadvantages and feasibility in current clinical practice.
- Trial name
- IMPETO (NCT03587259)
- Testing
- Tomosynthesis, 2D mammography
- Where
- 2 sites in Italy
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Cancer Prevention and Research Institute, Italy
Breast Cancer
Evaluation of the Efficacy of Digital Breast Tomosynthesis Imaging
The primary objective of this protocol is to collect the 2-dimensional (2D) screening and diagnostic images, and 3-dimensional (3D) Digital Breast Tomosynthesis (DBT) scans from patient mammography examinations acquired on…
- Trial name
- DBT (NCT01373671)
- Testing
- SIEMENS INSPIRATION DIGITAL BREAST TOMOSYNTHESIS (DBT) SYSTEM
- Where
- United States
- Volunteers
- 764 people, healthy volunteers welcome
- Sponsor
- Siemens Medical Solutions USA - CSG
Breast Cancer
Fujifilm Feature Comparison Reader Study to Compare Old vs New Processing
The purpose of the feature comparison study is to evaluate general mammographic features in images of the same breast when reconstructed with modified (ISR and DVIIm) processing as compared to the original processing (FBP with…
- Trial name
- NCT03586583
- Testing
- FBP, ISR
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Fujifilm Medical Systems USA, Inc.
Breast Cancer
Tomosynthesis Mammographic Imaging Screening Trial
A randomized screening trial to compare the diagnostic accuracy of screening for breast cancer with three-dimensional digital breast tomosynthesis (DBT) plus two-dimensional full-field digital mammography (FFDM) versus FFDM alone.
- Trial name
- TMISTLead-in (NCT02616432)
- Testing
- Tomosynthesis
- Where
- 4 sites in Canada
- Volunteers
- 3,065 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Breast Cancer
Digital Breast Tomosynthesis Guided Tomographic Optical Breast Imaging (TOBI)
Screening for breast cancer improves early detection of aggressive cancers and has been shown to reduce breast cancer related mortality.
- Trial name
- NCT02033486
- Testing
- TOBI + DBT
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Breast Cancer
Automated Breast Ultrasound and Digital Breast Tomosynthesis Screening Compared to Full Field Digital Mammography in Women With Dense Breasts
This study is investigating whether automated whole breast ultrasound can improve detection of cancer in breast cancer screening when used as a supplement to mammography or as a supplement to digital breast tomosynthesis
- Trial name
- NCT02042456
- Testing
- Digital Breast Tomosynthesis, Automated Whole Breast Ultrasound, Full Field Digital Mammography
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Breast Neoplasms
Delphinus SoftVue Prospective Case Collection - ARM 1
The SoftVue™ is a whole breast ultrasound system with an automated scanning curvilinear ring-array transducer that employs UST. It is currently cleared under FDA 510(k) K123209 and K142517 for use as both a B-mode ultrasonic…
- Trial name
- SV PCC ARM1 (NCT03257839)
- Testing
- Routine Full-Field Digital Mammography, Routine Digital Breast Tomosynthesis, Automated Whole Breast Ultrasound
- Where
- 10 sites in United States
- Volunteers
- 7,409 people, healthy volunteers welcome
- Sponsor
- Delphinus Medical Technologies, Inc.
Mammogram Scheduled
Comparison of Stationary Breast Tomosynthesis and 2-D Digital Mammography in Patients With Breast Augmentation
Purpose:The aim of this research is to compare the 3D s-DBT (stationary digital breast tomosynthesis) and conventional 2-D digital mammography devices with regards to patient comfort and radiologist preference in women with…
- Trial name
- NCT02008032
- Testing
- Stationary Breast Tomosynthesis
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Asymptomatic
Abbreviated Breast MRI and Digital Tomosynthesis Mammography in Screening Women With Dense Breasts
This randomized phase II trial studies how well abbreviated breast magnetic resonance imaging (MRI) and digital tomosynthesis mammography work in detecting cancer in women with dense breasts.
- Trial name
- NCT02933489
- Testing
- Contrast-enhanced Magnetic Resonance Imaging, Digital Tomosynthesis Mammography, Quality-of-Life Assessment
- Where
- 68 sites in United States, Germany
- Volunteers
- 1,516 people, healthy volunteers welcome
- Sponsor
- ECOG-ACRIN Cancer Research Group
Breast Screening
Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer
This randomized phase III trial studies digital tomosynthesis mammography and digital mammography in screening patients for breast cancer.
- Trial name
- NCT03233191
- Testing
- Digital Mammography, Digital Tomosynthesis Mammography, Laboratory Biomarker Analysis
- Where
- 149 sites in United States, Argentina and 9 more
- Volunteers
- 108,508 people, healthy volunteers welcome
- Sponsor
- ECOG-ACRIN Cancer Research Group
Breast Cancer
Multi-Reader Multi-Case Controlled Clinical Trial to Assess the Fujifilm FFDM and DBT Reader Training Program
The purpose of this pilot is to assess the adequacy of the Fujifilm DBT Reader Study Training program to ensure that Readers participating in the Fujifilm DBT pivotal trial are properly trained in the reading and interpretation…
- Trial name
- NCT02685566
- Testing
- FFDM Plus DBT, FFDM
- Where
- 5 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fujifilm Medical Systems USA, Inc.
Routine Screening Mammography
Acquisition and Clinical Image Evaluation of Fujifilm's High Resolution (HR) Digital Breast Tomosynthesis (DBT) Images.
Acquisition and clinical image evaluation of Fujifilm High Resolution (HR) Digital Breast Tomosynthesis (DBT) images.
- Trial name
- NCT07471750
- Testing
- DBT HR mode image acquisition
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Fujifilm Medical Systems USA, Inc.