Clinical trials: Disorder Heart
Diabetes Mellitus, Atrial Fibrillation
Dapagliflozin in Patients With Atrial Fibrillation (DAPA-AF)
The study will investigate the effect of Dapagliflozin on atrial fibrillation (AF) burden. AF burden will be defined as the percent of time spent in AF over a 2-week period, assessed by noninvasive continuous heart rhythm…
- Trial name
- NCT05174052
- Testing
- Dapagliflozin 10Mg Tab
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Oklahoma
Cardiovascular Diseases, Diabete Mellitus
Brazilian Diabetes Study: a Type 2 Diabetes Prospective Cohort
Ongoing prospective cohort of type 2 diabetes individuals.
- Conditions
- Cardiovascular Diseases, Diabete Mellitus, Coronary Artery Disease
- Trial name
- BDS (NCT04949152)
- Where
- Brazil
- Volunteers
- 1,046 people
- Sponsor
- University of Campinas, Brazil
Cardiovascular Diseases
Wearable Ultrasound for Cardiac Monitoring During Surgery and in Intensive Care
This study aims to evaluate the accuracy, feasibility, and clinical usefulness of a wearable ultrasound imaging system for cardiac monitoring during perioperative care and in intensive care units (ICUs).
- Trial name
- NCT07891052
- Testing
- Wearable Ultrasound Imaging System
- Volunteers
- 600 people
- Sponsor
- China National Center for Cardiovascular Diseases
Hypoxic Encephalopathy
The Neurological Pupil Index (NPi) on Intensive Care Unit (ICU) Trial
The trial will evaluate the use of the "Neurological Pupil index" NPi, measured with the digital pupillometer (NeurOptics) compared to clinical examination for better reliability.
- Trial name
- NPI-ON-ICU (NCT01920347)
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
Arteriovenous Fistula, Arteriovenous Graft
Access Creation for Hemodialysis: Association With Structural Changes of the Heart
The purpose of this study is to determine if the creation of a fistula or a graft plays a role in the development of heart disease for patients undergoing hemodialysis
- Conditions
- Arteriovenous Fistula, Arteriovenous Graft, Left Ventricular Hypertrophy, Brain Natriuretic Peptide
- Trial name
- NCT00368147
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Ottawa Hospital Research Institute
Coronary Disease
Coronary Disease and the Effect of High-intensity Interval Training
The primary purpose of this study is to investigate if systematic, high intensity, interval-based aerobic exercise training results in regression of lipid content of atherosclerotic coronary artery plaques, and in reduction of…
- Trial name
- CENIT (NCT02494947)
- Testing
- high intensity interval-based aerobic exercise, Usual care
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Norwegian University of Science and Technology
Tricuspid Regurgitation
TRILUMINATE Pivotal Trial
The primary objective of this trial is to demonstrate the safety and effectiveness of the TriClip device in improving clinical outcomes in symptomatic patients with severe tricuspid regurgitation (TR), who are at intermediate or…
- Trial name
- NCT03904147
- Testing
- TriClipTM Device
- Where
- 76 sites in United States, Canada and 3 more
- Volunteers
- 572 people
- Sponsor
- Abbott Medical Devices
SIRS, Cytokine Storm
Cytokine Hemoadsorption in ECMO Patients
Cytokine hemoadsorption is a novel therapy used to improve outcome in critically ill patients with a dysregulated cytokine response and hemodynamic instability.
- Conditions
- SIRS, Cytokine Storm, Cardiogenic Shock, Cardiac Arrest
- Trial name
- NCT04901338
- Where
- Slovenia
- Volunteers
- 25 people
- Sponsor
- University Medical Centre Ljubljana
STEMI
Intensive Statin Treatment for STEMI Patients Undergoing Primary PCI
This is a retrospective, randomized, parallel, open-labeled, controlled study to find out whether STEMI patients undergoing emergency PCI can benefit from intensive atorvastatin treatment compared with routine treatment.
- Trial name
- NCT01033058
- Testing
- atorvastatin
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Beijing Chao Yang Hospital
Heart Failure
The WiSE®-UP Study (The WiSE System Utilization & Performance Study)
Observe to understand product performance, including patient safety, clinical outcomes, and CRT response information associated with the use of the market-released WiSE System
- Trial name
- NCT07098858
- Testing
- The Wise System
- Where
- 12 sites in United States
- Volunteers
- 320 people
- Sponsor
- EBR Systems, Inc.
Atrial Fibrillation
The RECORD Asia-Pacific Atrial Fibrillation Registry
The Primary objective of this registry is to assess the control of Atrial Fibrillation (AF) over one year in patients attending clinical or specialized practices.
- Trial name
- RECORDAF-AP (NCT00995748)
- Where
- 8 sites in Australia, China and 6 more
- Volunteers
- 2,674 people
- Sponsor
- Sanofi
Extracorporeal Life Support, Hypotension
Hypotension During Extracorporeal Circulatory Support Indicated for Cardiogenic Shock
The cardiogenic shock is characterized by an alteration of organs function following a decrease in cardiac output linked to an impairment of cardiac performance. The prognosis remains poor with mortality between 40 and 50%.
- Conditions
- Extracorporeal Life Support, Hypotension, Vasoplegia
- Trial name
- RetroECMO-VP (NCT03968926)
- Testing
- Arterial pressure management during circulatory support by VA-ECMO
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Hypertrophic Obstructive Cardiomyopathy, Mitral Regurgitation
Mitral Regurgitation in Hypertrophic Obstructive Cardiomyopathy: Fix it in a Simple, Effective and Durable Way!
Septal myectomy is performed in selected cases to treat patients with hypertrophic obstructive cardiomyopathy (HOCM). The mechanism that causes obstruction involves both the outflow tract itself and the mitral apparatus, with the…
- Trial name
- NCT05850026
- Testing
- Septal myectomy and mitral valve repair with edge-to-edge technique
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Michele De Bonis
Cardiovascular Diseases, Heart Diseases
Study of Children's Activity and Nutrition (SCAN)
In the first study, to identify children at high and low risk for cardiovascular disease and study their nutritional and physical activity behaviors as they relate to cardiovascular disease.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Hypertension
- Trial name
- NCT00005178
- Sponsor
- Augusta University
Anemia in Children, Cardiomegaly
The Association Between Anemia and Cardiomegaly
Anemia is one of the major global problems that continues to this day. According to World Health Organization (WHO) data, anemia is found in 1.62 billion people or equivalent to 24.8% of the world's population while, the…
- Trial name
- NCT05816278
- Where
- Indonesia
- Volunteers
- 56 people
- Sponsor
- Universitas Sumatera Utara
Ischemic Heart Disease, ST-segment Elevation Myocardial Infarction
Late Reperfusion With Percutaneous Coronary Intervention in Patients With ST-segment Elevation Myocardial Infarction
Although recommended therapy for patients with ST-segment elevation myocardial infarction is primary PCI, it remains unestablished whether patients with a symptom duration of more 12 hours benefit from acute revascularisation.
- Trial name
- LATE-MI (NCT02445885)
- Testing
- PCI
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Thomas Engstrom
STEMI
Effect of rhBNP on CMD in Patients With STEMI After PPCI
The target population of this interventional study was STEMI patients. Primary discussion: Early rhBNP reduces microcirculation obstruction in STEMI patients undergoing primary PCI
- Trial name
- NCT05723315
- Testing
- recombinant human B-type natriuretic peptide
- Volunteers
- 160 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Radial Artery Spasm, Angina
Topical Nitroglycerine Treatment for Radial Artery Spasm Prevention
The primary objective of the study is to determine the role of transdermal vasodilators as an adjunct to parenteral vasodilators in reducing radial artery spasm, improving patient comfort, and post procedure radial artery patency…
- Conditions
- Radial Artery Spasm, Angina, Coronary Artery Disease
- Trial name
- TNT-RASP (NCT02832115)
- Testing
- Topical Nitroglycerine, Topical Lidocaine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Aultman Health Foundation
Myocardial Disease
Cardiovascular Events for a Long Time End of COVID 19 Infection
In the follow-up of partecipants with Covid-19 infection, persistence of cardiovascular symptoms is common. Studies on the acute phase of Covid-19 infection have demonstrated a significant prevalence of acute myocardial damage…
- Trial name
- LONGCOVIDWP3 (NCT05729152)
- Testing
- Sample blood
- Where
- 2 sites in Italy
- Volunteers
- 240 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Atrial Fibrillation
Comparative Effectiveness of Oral Anticoagulants
This cohort study plans to identify initiators of oral anticoagulants using electronic claims data from a commercial insurance database to quantify associations between anticoagulant choice (warfarin and dabigatran) and the…
- Trial name
- NCT01847547
- Volunteers
- 5,982 people
- Sponsor
- Boehringer Ingelheim
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.