Clinical trials: Disturbed Sleep
Stress, Anxiety
Effects of Coherent Breathing Breathwork on Health
The investigators are conducting a randomised-controlled trial comparing coherent breathing at ~5.5 breath cycles per minute-bcpm (with equal inhalation/exhalation durations of ~5.5secs each) to a well-designed placebo (paced…
- Conditions
- Stress, Anxiety, Depressive Symptoms, Wellbeing
- Trial name
- NCT05676658
- Testing
- Coherent breathing
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Sussex
Sleep Disturbance, Stress, Psychological
Wearable Neural Interfacing System for REM Sleep Restoration and Enhancement
This study evaluates a wearable system (NEUSleeP) that combines overnight EEG recording with transcranial focused ultrasound (tFUS) targeted to deep brain structures involved in REM sleep regulation (e.g., subthalamic nucleus).
- Conditions
- Sleep Disturbance, Stress, Psychological, REM Sleep Measurement
- Trial name
- NEUSleeP (NCT07190287)
- Testing
- NEUSleeP system (FUS-EEG wearable device), BrainSonix Pulsar 1002
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Postoperative Sleep Disturbance
Dexmedetomidine Premedication for Post-anaesthesia Sleep Disturbance
The goal of this clinical trial is to learn about the effect of preoperative nasal spry with dexmedetomidine on postoperative sleep disturbance in young to middle-aged women undergoing hysteroscopy.
- Trial name
- NCT06281561
- Testing
- Normal Saline, Dexmedetomidine
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Xiamen University
Chronic Low Back Pain (CLBP), Chronic Insomnia
Studying the Neurobiological Mechanisms of Non-specific Chronic Low Back Pain and Chronic Insomnia: a Four-group Cross-sectional Study
This study is a part of a larger project aiming to evaluate the neurobiological mechanisms underlying the relationship between sleep and pain in people with non-specific chronic low back pain.
- Conditions
- Chronic Low Back Pain (CLBP), Chronic Insomnia, Neuroinflammation
- Trial name
- SY-NAPS-CS (NCT06973837)
- Testing
- Real-life monitoring, experimental pain testing, brain imaging, blood and stool sampling.
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Sleep Disturbance
Human Centric Lighting to Improve Patient Sleep Parameters
Human centric lighting (HCL) is a technology that supports the body's circadian rhythm, as it can stimulate the sleep triggering hormone, melatonin, to improve sleep hygiene over standard lighting (SL), and promote recuperative…
- Trial name
- NCT05039749
- Testing
- Human Centric Lights
- Where
- Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Landstuhl Regional Medical Center
Sleep Disturbance, Stress
Yoga for Persons With Severe Visual Impairment
This study aims to provide novel information on the feasibility of yoga interventions for secondary symptoms related to severe vision loss, such as sleep disturbances, negative mood states, fall risk and balance.
- Conditions
- Sleep Disturbance, Stress, Anxiety, Depression
- Trial name
- RPY (NCT01366677)
- Testing
- Yoga Intervention
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Alcohol Dependence, Insomnia
Pharmacotherapy and Mechanisms of Sleep Disturbance in Alcohol Dependence
Insomnia and other sleep abnormalities are common, persistent, and associated with relapse in alcohol-dependent patients. The overall, long-term objectives of the proposed research are to investigate the neurophysiologic…
- Trial name
- MA (NCT01014533)
- Testing
- Gabapentin dispensed to subject.
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Dr. Kirk Brower
Sleep Disturbance, Insomnia
Music Interventions for the Facilitation of Sleep in the Acute Geriatric Setting
Sleep disturbance is a common problem experienced by older patients, especially in the acute care setting, and has detrimental effects on patients' health and recovery.
- Conditions
- Sleep Disturbance, Insomnia, Music Listening Intervention, Non-musical Sound Listening Intervention
- Trial name
- NCT05398419
- Testing
- Music listening intervention, Non-musical sounds listening intervention
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- McGill University
Healthy
Influence of Manual and Electrical Vagal Stimulation on Autonomic Activity and Other Dysautonomous Symptoms in a Healthy Population.
The objective of this clinical, longitudinal, prospective, randomised (randomised) unmasked study is to analyse whether electrical and manual vagal stimulation produces changes in heart rate variability in a healthy population…
- Trial name
- NCT07660744
- Testing
- Electrical stimulation of the vagus nerve, Manual stimulation of vagus nerve
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Escoles Universitaries Gimbernat
Post Traumatic Stress Disorder, Sleep Disturbance
Acupuncture for Sleep Disturbances in OEF/OIF Veterans With Post Traumatic Stress Disorder
Post traumatic stress disorder (PTSD) has emerged as a significant problem among troops returning from combat zones. A majority of these veterans will report difficulty maintaining or initiating sleep.
- Trial name
- NCT01862653
- Testing
- Auricular Acupuncture
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Sleep Disturbance, Total Joint Arthroplasty
Randomized Trial Investigating Melatonin Supplementation vs Placebo on Sleep Disturbance Following Total Joint Arthroplasty
The purpose of this study is to determine whether melatonin when used as a supplement after surgery improves sleep following total joint arthroplasty
- Trial name
- NCT04590742
- Testing
- melatonin 6mg
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Pain, Postoperative, Sleep Disturbance
The Effect of Foot Massage After Open Heart Surgery on Postoperative Pain, Sleep Quality and Mood of Patients
The randomized controlled experimental study was conducted in the cardiovascular surgery clinic of Atatürk University Health Practice and Research Center between April 2021 and September 2021.The research sample consisted of 91…
- Conditions
- Pain, Postoperative, Sleep Disturbance, Mood, Bypass Complication
- Trial name
- NCT05567107
- Testing
- massage
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Sleep Disturbance, Mental Health Wellness 1
Effects of Health and Wellness App on Employee Productivity
The purpose of this study is to test the effects of using the Calm app + coaching concierge (one 20-min session) and/or Calm Coaching for sleep program on sleep, mental health, and work productivity outcomes in employees.
- Trial name
- NCT05120310
- Testing
- The Calm App
- Where
- United States
- Volunteers
- 1,029 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Sleep Disturbance, Emotional Disturbance
Pilot Trial for Health Products on Mood and Sleep Quality
This is a pilot, single-site clinical trial that will follow a randomized, double-blinded, parallel-group, placebo-controlled design.
- Trial name
- NCT06579183
- Testing
- Vita Calm Mood Booster Formula (VCMBF), Vita Calm Deep Sleep Formula (VCDSF)
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Yoga
The Effect of Yoga Self-Practice on Sleep Disturbance
The study will examine the effect of Restorative Yoga self-practice on sleep disturbance in the Chinese adult population. Restorative Yoga is a relaxation-focused yoga style which includes a series of static stretching poses and…
- Trial name
- NCT04719039
- Testing
- Restorative Yoga Internvention
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Sleep Disturbances, Anxiety
Prevalence and Association of Anxiety and Sleep Disturbances Among Medical Students.
Observational, Cross-sectional study
- Trial name
- NCT06953102
- Testing
- Survey using a questionnaire.
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Government Medical College, Patiala
Noise Exposure, Sleep Disturbance
Effects of Railway Vibration on Sleep and Disease
This study will investigate the biological mechanisms linking sleep disruption by vibration and noise, and the development of cardiometabolic disease.
- Conditions
- Noise Exposure, Sleep Disturbance, Sleep Hygiene, Metabolic Disturbance
- Trial name
- BioVib (NCT06260254)
- Testing
- Railway noise, Low level railway vibration, Intermediate level railway vibration
- Where
- Sweden
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Restless Legs Syndrome, Sleep Quality
Restless Legs Syndrome and Sleep Quality in Pes Planus
Pes planus, also known as flatfoot, is a common foot deformity that can affect the biomechanics of the lower limbs. However, its relationship with neurological conditions has not been studied extensively.
- Conditions
- Restless Legs Syndrome, Sleep Quality, Pain, Quality of Life
- Trial name
- FLAT-RLS (NCT07117591)
- Where
- Turkey (Türkiye)
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Bozok University
Breast Neoplasm Female, Symptom Cluster
Effects of a Traditional Chinese Exercise Program on Symptom Cluster in Breast Cancer Patients
The Medical Research Council Framework for Developing and Evaluating Complex Interventions (MRC Framework) will be utilized to develop and evaluate an evidence-based tai chi intervention for managing the symptom cluster of…
- Conditions
- Breast Neoplasm Female, Symptom Cluster, Tai ji
- Trial name
- NCT04190342
- Testing
- control group, tai chi group
- Where
- 2 sites in China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Charles Darwin University
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data