Clinical trials: Diverticulum
Diverticular Disease
Evaluation of Efficacy of Mesalamine in the Long-term Prevention of Diverticulitis Flares
The purpose of this study is to determine whether mesalamine is effective vs. placebo in the prevention of diverticulitis flares in a 24-months follow-up.
- Trial name
- DIV-01/04 (NCT01120340)
- Testing
- mesalamine
- Where
- 17 sites in Italy
- Volunteers
- 105 people
- Sponsor
- SOFAR S.p.A.
Inflammatory Bowel Diseases, Colon Cancer
Pre-Habilitation Exercise Intervention
The purpose of this study is to see whether exercise can improve the health and well-being of patients scheduled to undergo surgery for a bowel related condition.
- Conditions
- Inflammatory Bowel Diseases, Colon Cancer, Rectal Cancer, Diverticular Disease
- Trial name
- NCT02849717
- Testing
- Exercise for Cancer Patients
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Rochester
Colon Adenoma, Diverticulosis
Impact of Diverticular Disease on the Detection of Colon Adenomas
Benign adenomas of the colon have the potential to degenerate and become malignant. Therefore adenomatous polyps should be detected and resected during colonoscopy.
- Trial name
- DECADE (NCT02057562)
- Where
- 2 sites in Germany
- Volunteers
- 1,000 people
- Sponsor
- Technical University of Munich
Diverticular Disease
DD Obesity MRI Study
In this study, our novel MRI techniques for studying the small bowel will be applied to patients with diverticular disease. The ratio of visceral to subcutaneous fat will also be determined using MRI measurements.
- Trial name
- DDOMRI (NCT02278770)
- Volunteers
- 58 people
- Sponsor
- University of Nottingham
Diverticulosis, Colonic, Microbiota
Influence of Mechanical Bowel Preparation on GI Microbiota
The mechanical bowel preparation (BP) used to clean the colon prior to colonoscopy frequently results in a significant but temporary reduction in patient's symptoms for a number of bowel disorders including symptomatic…
- Trial name
- NCT03465293
- Testing
- Bacterial composition and activity after bowel preparation
- Volunteers
- 15 people
- Sponsor
- University of Reading
Diverticulum, Esophageal, Post Gastric Surgery Syndrome
MAgnetic Gastrointestinal Universal Septotome: a Safety and Feasibility Study (MAGUS)
A novel magnetic device, called MAgnetic Gastrointestinal Universal Septotome (MAGUS) was designed to improve the Treatment of diverticulum of the esophagus, Pseudo-diverticulum of the upper GI tract, Candy cane syndrome This…
- Trial name
- MAGUS (NCT04480216)
- Testing
- MAGUS
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- Erasme University Hospital
Diverticulitis, Diverticulosis
The Gut Microbiome in Diverticulitis and Diverticulosis
Colonic diverticula are outpouchings of the large bowel, and they occur in up to 60% of people over 60 years of age. About 10-25% of patients with diverticula will have symptoms.
- Conditions
- Diverticulitis, Diverticulosis, Diverticular Disease
- Trial name
- NCT02221713
- Where
- United Kingdom
- Sponsor
- King's College Hospital NHS Trust
Diverticulosis, Diverticulitis
Role Of Lactobacillus Reuteri DSM 17938 In The Non-Complicated Diverticular Disease
The aim of this study is to evaluate the effectiveness and the tolerability of the Lactobacillus reuteri in the control of the diverticular disease symptoms and in the prevention of acute diverticulitis episodes.
- Trial name
- ReDiCo (NCT01168154)
- Testing
- Lactobacillus Reuterii
- Where
- 2 sites in Italy
- Volunteers
- 160 people
- Sponsor
- Casa Sollievo della Sofferenza IRCCS
Diverticular Disease of Colon, Diverticulosis, Colonic
Prevalence of Segmental Colitis Associated With Colic Diverticulosis (SCAD)
Colonic diverticula are common in Western countries, affecting up to 60% of subjects over 70 years of age. In about 80% of patients, colonic diverticula remain asymptomatic (diverticulosis), while approximately 20% of patients…
- Trial name
- NCT04279821
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Roma La Sapienza
Diverticular Disease
Prophylactic Endoscopic Clipping of Diverticula (PECoD)
This study will evaluate the effect of endoscopic clipping of colonic diverticula in treatment of symptoms related to diverticular disease.
- Trial name
- PECoD (NCT03935100)
- Testing
- Endoscopic clipping
- Where
- United Kingdom
- Volunteers
- 84 people
- Sponsor
- King's College Hospital NHS Trust
Diverticulum, Colon, Colorectal Neoplasms
Data Collection of Patients Treated With the ColonRing™ for the Creation of Circular Compression Anastomosis
The proposed study is a post marketing, observational, retrospective data collection intended to gather and record data on patients treated with the ColonRing™ device in routine clinical practice at a single center.
- Conditions
- Diverticulum, Colon, Colorectal Neoplasms, Crohn Disease, Colitis, Ulcerative
- Trial name
- RETROPRESS (NCT01301417)
- Testing
- ColonRing™
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- novoGI
Zenker Diverticulum, Progressive Dysphagia
Cricopharyngeal Dysfunction and Esophageal Diverticulum
Patients undergoing open transcervical or endoscopic approach in which a laser or stapler is used to divide the common wall between the diverticulum and esophagus, or who are not surgical candidates but agree to follow-up.
- Conditions
- Zenker Diverticulum, Progressive Dysphagia, Pharyngoesophageal Diverticulum
- Trial name
- NCT03187925
- Testing
- open, transcervical versus rigid endoscopic treatment
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Cincinnati
Symptomatic Recurrent Diverticular Disease, Benign Adenomatous Sigmoidal Polyp, Requiring Surgery
Randomized Trial Comparing Laparoscopic-assisted Rectosigmoid Resection Versus Laparoscopic Rectosigmoid Resection With Transrectal Specimen Retrieval
Laparoscopic anterior resection is a standardized procedure requiring a small muscle split incision to retrieve the specimen and to fashion the proximal part of the double stapled anastomosis.
- Conditions
- Symptomatic Recurrent Diverticular Disease, Benign Adenomatous Sigmoidal Polyp, Requiring Surgery, Early Non-transmural Sigmoidtumor
- Trial name
- LATA (NCT01033838)
- Testing
- rectosigmoid resection
- Where
- Belgium
- Volunteers
- 1 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Sigmoid Diverticulosis, Sigmoid Diverticulitis
Feasibility, Safety and Outcome of Transrectal Hybrid-NOTES Anterior Resection
Natural orifice transluminal endoscopic surgery has become an important topic. NOTES access routes give the opportunity to reduce surgical access trauma leading to a more painless surgery and enhancing a fast postoperative…
- Conditions
- Sigmoid Diverticulosis, Sigmoid Diverticulitis, Colon Adenoma, Rectal Prolapse
- Trial name
- NCT01992406
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Cantonal Hospital, Baselland
Diverticulum, Colon, Colorectal Neoplasms
A RETROspective Data Collection of comPRESSion Anastomosis Using the ColonRing
The proposed study is a post marketing, observational, retrospective data collection intended to gather and record data on patients treated with the ColonRing device in routine clinical practice at 4-6 centers.
- Conditions
- Diverticulum, Colon, Colorectal Neoplasms, Crohn Disease, Colitis, Ulcerative
- Trial name
- NCT01880918
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- novoGI
Defecatory Disorders After Left Colonic or Rectal Resection
Improvement of Anorectal Function While Preserving of Inferior Mesenteric Artery Performing Left Hemicolectomy for Diverticulosis
The aim of the study is to evaluate the anorectal function after hemicolectomy if we preserve or not the Inferior Mesenteric Artery (IMA).
- Trial name
- IPIMAL (NCT01326052)
- Testing
- Inferior Mesenteric Artery Preservation, Inferior Mesenteric Artery Ligation
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- University of Roma La Sapienza
Colon Cancer, Diverticulum, Colon
ERAS Lazio Network Clinical Registry
Enhanced recovery after surgery (ERAS) protocols are programs aiming to implement patients recovery following surgical procedures developed about 25 years ago.
- Trial name
- ENeRgy (NCT03353311)
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- PERSIANI ROBERTO
Diverticulitis, Colonic, Colonic Neoplasms
Acute Diverticulitis and Advanced Colonic Neoplasia. When to Perform Colonoscopy (ADACOLON Study)
This study evaluate the prevalence of advanced colonic neoplasia (ACN) in acute diverticulitis. A sub-analysis of complicated and uncomplicated acute diverticulitis will be made in order to determinate whether there are…
- Trial name
- ADACOLON (NCT03557216)
- Testing
- Colonoscopy, Fecal immunochemical and occult blood test, Fecal calprotectin test
- Where
- Spain
- Volunteers
- 313 people
- Sponsor
- Parc de Salut Mar
Achalasia, Esophageal Spasm, Diffuse
Prospective Evaluation of the Clinical Utility of Peroral Endoscopic Myotomy for Gastrointestinal Motility Disorders
This is prospective data recording study. All patients will receive standard medical care and no experimental interventions will be performed.
- Conditions
- Achalasia, Esophageal Spasm, Diffuse, Gastroparesis, Swallowing Disorder
- Trial name
- POEM (NCT05905016)
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- AdventHealth
Oesophageal Disease
Endomina Diverticulum
Esophageal diverticulum is a rare disease. Majority comes form the pharyngo-esophageal junction (70 % Zenker's Diverticulum), 10% are mediothoracic and 20% epiphrenic.
- Trial name
- NCT03609073
- Testing
- Endomina
- Where
- Belgium
- Volunteers
- 4 people
- Sponsor
- Erasme University Hospital