Clinical trials: Drug Eluting Stents
Coronary Disease
Optimal Physiologic Intravascular Ultrasound Imaging Criteria After Drug Eluting Stent Implantation
Invasive imaging criteria of the Coronary arteriography (CAG) and intravascular ultrasound imaging (IVUS), satisfying procedural optimization after drug eluting stent (DES) implantation, were used in < 10% DS by CAG and 5-5.5mm2…
- Trial name
- NCT01667757
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Inje University
Patients in the Treatment of Subjects With All-comer Who Are to Undergo PCI
Comparison of the 3-month Strut Coverage After Coronary Stenting by Optical Coherence Tomography; Cilotax and DESyne
We will compare the stent coverage at 3 months by optical coherence tomography (OCT) between the Cilotax and DESyne drug-eluting stents (DES).
- Trial name
- NCT02060175
- Testing
- Cilotax drug-eluting stents implantation, DESyne drug-eluting stents implantation
- Sponsor
- Yonsei University
Coronary Artery Disease
SYNTAX Study: TAXUS Drug-Eluting Stent Versus Coronary Artery Bypass Surgery for the Treatment of Narrowed Arteries
The SYNTAX trial is designed to determine the best treatment for patients with complex coronary disease (blocked or narrowed arteries in both the right and left sides of the heart) by randomizing patients to receive either…
- Trial name
- SYNTAX (NCT00114972)
- Testing
- Polymer-based Paclitaxel-Eluting TAXUS Express2-SR Stent, Coronary Artery Bypass Surgery
- Where
- 106 sites in United States, Austria and 16 more
- Volunteers
- 1,800 people
- Sponsor
- Boston Scientific Corporation
Heart Disease, Myocardial Ischaemia
Safety and Efficacy Study of Hybrid Revascularization in Multivessel Coronary Artery Disease
The purpose of the study is to assess the safety and efficacy of hybrid revascularization in comparison with coronary artery bypass grafting among patients with multivessel coronary artery disease.
- Conditions
- Heart Disease, Myocardial Ischaemia, Coronary Disease, Coronary Artery Disease
- Trial name
- POL-MIDES (NCT01035567)
- Testing
- Hybrid revascularization, Coronary Artery Bypass Grafting
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- Silesian Centre for Heart Diseases
Ischemic Stroke
Bare -Metal Stents and Drug -Eluting Stents in the Treatment of Patients With Vertebral Artery Ostium Stenosis
The study hypothesizes that Drug -eluting stents are more effective in preventing restenosis than Bare-metal stents after Vertebral Artery Ostium stenting
- Trial name
- NCT02197559
- Testing
- DES group, BMS group
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Xuanwu Hospital, Beijing
Out of Hospital Cardiac Arrest, Stent Thrombosis
Definite Stent Thrombosis in Comatose Out of Hospital Cardiac Arrest Survivors
Reliable data on stent thrombosis (ST) in comatose out of hospital cardiac arrest (OHCA) survivors is lacking. In comatose OHCA survivors suspicion of ST can be made with precise clinical monitoring of the patient with definite…
- Conditions
- Out of Hospital Cardiac Arrest, Stent Thrombosis, Drug Eluting Stent, Therapeutic Hypothermia
- Trial name
- ST OHCA (NCT03312296)
- Where
- Slovenia
- Volunteers
- 151 people
- Sponsor
- University Medical Centre Ljubljana
Coronary Artery Disease, Coronary Artery Stenosis
To Evaluate the Performance and Safety of RisoR Crest Everolimus Eluting Coronary Stent System
The study will evaluate the performance and safety of RisoR Crest Everolimus Eluting Coronary Stent System. A total of 2000 participants will be included in the study from India and Italy.
- Conditions
- Coronary Artery Disease, Coronary Artery Stenosis, Percutaneous Coronary Intervention, de Novo Lesions in Native Coronary Arteries
- Trial name
- PACIFIER (NCT07098195)
- Testing
- Coronary Stent
- Volunteers
- 2,000 people
- Sponsor
- Poly Medicure Limited
Coronary Artery Disease
XLIMus Drug Eluting Stent: a randomIzed Controlled Trial to Assess Endothelization
The objective of the study is to assess angiographic and clinical performance of Xlimus Drug Eluting Stent (DES) compared to Synergy Bioabsorbable Polymer Everolimus Eluting Stent in patients treated with percutaneous coronary…
- Trial name
- XLIMIT (NCT03745053)
- Testing
- Xlimus DES Implantation during coronary angioplasty, Synergy DES Implantation during coronary angioplasty
- Where
- 4 sites in Italy, Spain
- Volunteers
- 180 people
- Sponsor
- Cardionovum GmbH
Percutaneous Coronary Intervention, Stents
Xience V at Wake Forest University Baptist Medical Center (WFUBMC)
The effectiveness, safety, and deliverability of second generation drug eluting stents (DES), including Xience V, will need to be examined in real world patients to provide the same level of evidence base and comfort that has…
- Trial name
- NCT00937573
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Wake Forest University
Coronary Artery Disease
A Study to Examine the Implantation Characteristics of Two Drug-Eluting Stents
Despite recent advances in stent technology and clot reducing drug therapy, acute stent occlusion or thrombosis (ST), still occurs and can be life threatening.
- Trial name
- ORCA-2 (NCT01201369)
- Testing
- Coronary Stent Cypher, Coronary stent Xience
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Peripheral Arterial Disease (PAD)
Zilver Flex Post-Market Study in Japan
Japanese post market clinical study of the Zilver Flex device.
- Trial name
- NCT02254356
- Testing
- Zilver Flex Bare Metal Stent
- Where
- Japan
- Volunteers
- 239 people
- Sponsor
- Cook Group Incorporated
Acute Coronary Syndrome
Clopidogrel Maintaining Dosage in Acute Coronary Syndrome After Drug Eluting Stent Implantation
In view of its safety profile and the results of clinical trials, clopidogrel has become the standard treatment for patients with acute coronary syndrome (ACS) and drug eluting stent(DES) implantation.
- Trial name
- NCT00404053
- Testing
- Clopidogrel
- Sponsor
- Shenyang Northern Hospital
Peripheral Arterial Disease
The Cre8™ BTK Post Market Clinical Follow-up Study
Cre8™ BTK is a CE marked drug eluting stent, integrally coated with i-Carbofilm, loaded with formulated Sirolimus for the treatment of infrapopliteal peripheral artery disease.
- Trial name
- NCT05616156
- Testing
- Cre8™ BTK
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- CID S.p.A.
Cardiovascular Diseases, Vascular Disease
An Observational Registry Using Drug Eluting Stents (DES) in Patients in a Real-World Setting (DEScover Registry).
The DEScover Registry is designed to observe the results of using Drug Eluting Stents (DES) in patients in a real-world setting.
- Conditions
- Cardiovascular Diseases, Vascular Disease, Arterial Occlusive Disease, Arteriosclerosis
- Trial name
- DESCOVER (NCT00489320)
- Testing
- Cypher Stent
- Where
- United States
- Volunteers
- 7,759 people
- Sponsor
- Cordis US Corp.
Diabetes, Coronaropathy
Safety and Performance Assessment of Drug-Eluting Stent CRE8 in Diabetic Patients
The study is a 'real-world' study which evaluates the safety and performance of the coronary DES-CRE8 in diabetic patients. As routine care, each patient will be followed until 12 months after stent implantation.
- Trial name
- EVALU8 (NCT03842813)
- Testing
- DES-CRE8
- Where
- 22 sites in France
- Volunteers
- 1,030 people
- Sponsor
- Alvimedica Medical Technologies France
Coronary Artery Disease, Drug Eluting Stents
Impact of Stepwise Pressure-Increasing NC Balloon Post-Dilation on Stent Expansion
This is a prospective, single-center, single-arm exploratory observational study aiming to evaluate the impact of stepwise pressure-increasing non-compliant (NC) balloon post-dilation on stent expansion rate in patients…
- Trial name
- SPND (NCT07853261)
- Testing
- Coronary stent + non-compliant post-dilation balloon
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Jilin University
Coronary Artery Disease
EDUCATE: The MEDTRONIC Endeavor Drug Eluting Stenting: Understanding Care, Antiplatelet Agents and Thrombotic Events
EDUCATE is a prospective, multi-center study designed to collect real-world safety and clinical outcomes in subjects receiving one or more Endeavor Zotarolimus-Eluting Stents and either clopidogrel and aspirin or prasugrel and…
- Trial name
- EDUCATE (NCT01069003)
- Testing
- Thienopyridine Therapy, Surveillance Arm
- Where
- United States
- Volunteers
- 2,272 people
- Sponsor
- Medtronic Vascular
Coronary Artery Disease
Deutsches Dual Therapy Stent Register
The DTS.DE registry is an initiative for the collection of high quality process and historical data of implantations with the COMBO Dual Therapy Stent in Germany.
- Trial name
- DTS Register (NCT02102997)
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- OrbusNeich
Chronic Coronary Occlusion, Unprotected Left Main Coronary Artery Disease
EXCEL Clinical Trial
To establish the safety and efficacy of the commercially approved XIENCE Family Stent System (inclusive of XIENCE PRIME, XIENCE V, XIENCE Xpedition and XIENCE PRO [for use outside the United States [OUS] only]) in subjects with…
- Conditions
- Chronic Coronary Occlusion, Unprotected Left Main Coronary Artery Disease, Stent Thrombosis, Vascular Disease
- Trial name
- EXCEL (NCT01205776)
- Testing
- Percutaneous Coronary Intervention, CABG
- Where
- United States
- Volunteers
- 1,905 people
- Sponsor
- Abbott Medical Devices
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Hungary Satellite Registry
This registry is a clinical post-market evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES)
- Trial name
- NCT01892917
- Where
- 13 sites in Hungary
- Volunteers
- 2,000 people
- Sponsor
- Biotronik Hungária Kft.