Clinical trials: Duration of Pain Relief
Duration of Pain Relief
Dexamethasone and Block Duration in Upper Extremity
Effect of dexamethasone on prolonging upper extremity block is well known. But it not known if the effect comes from its local effect on the nerves or from its general analgesic effect.
- Trial name
- NCT01756573
- Testing
- Dexamthsone, Bupivacaine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Chicago
Chronic Pain
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time
The primary objective of this study is to evaluate efficacy of hydrocodone extended-release (ER) tablets compared with placebo in alleviating moderate to severe pain in patients with osteoarthritis or low back pain as assessed by…
- Trial name
- NCT01240863
- Testing
- Hydrocodone ER
- Where
- 73 sites in United States
- Volunteers
- 391 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Muscle Spasm
Low Intensity Ultrasound Therapy for Upper Back Pain Relief
The purpose of this study is to measure the effectiveness of a wearable therapeutic ultrasound device for relief of pain associated with the trapezius muscle of the upper back over a 4-week period.
- Trial name
- NCT02135094
- Testing
- Active ultrasound therapy device
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- ZetrOZ, Inc.
Low Back Pain
Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets for Moderate to Severe Chronic Low Back Pain
The primary objective of this study is to evaluate the efficacy of hydrocodone bitartrate extended-release tablets at doses of 30 to 90 mg every 12 hours compared with placebo in alleviating moderate to severe pain in patients…
- Trial name
- NCT01789970
- Testing
- Hydrocodone ER
- Where
- 87 sites in United States
- Volunteers
- 625 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Low Back Pain
Open-Label, Extension Study to Evaluate the Safety of Hydrocodone Bitartrate Extended-Release Tablets
This is a 6-month, nonrandomized, open-label extension study to assess the long-term safety of hydrocodone bitartrate extended-release (ER) tablets in patients with moderate to severe chronic low back pain who require continuous…
- Trial name
- NCT01922739
- Testing
- Hydrocodone ER
- Where
- 61 sites in United States
- Volunteers
- 182 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Postoperative Pain
Comparison of Pain Relief Duration With Dexmedetomidine Versus Fentanyl Added to Spinal Anesthesia in Patients Undergoing Lower Limb Orthopedic Surgery
The goal of this randomized clinical trial is to compare how long effective pain relief lasts when dexmedetomidine or fentanyl is added to hyperbaric bupivacaine during spinal anesthesia for lower limb orthopedic surgery.
- Trial name
- NCT07770542
- Testing
- Dexmedetomidine & Bupivacaine., fentanyl and bupivacaine
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Allama Iqbal Teaching Hospital
Pain
CREMS Prostate Biopsy Pain Relief Study
The current standard for pain relief during prostate biopsy is the injection of local anesthetic agents into or around the prostate at various sites including apex, base, lateral aspects and into the prostate itself.
- Trial name
- NCT01365871
- Testing
- anesthetics injection
- Volunteers
- 300 people
- Sponsor
- University Health Network, Toronto
Pain
Bupivacaine Digital Blocks: How Long is the Pain Relief and Temperature Elevation?
No one knows how long bupivacaine finger blocks last. Many use bupivacaine with and without epinephrine, but no one knows how the epinephrine affects the duration of the block.
- Trial name
- NCT01698593
- Testing
- Bupivacaine 0.5%, Bupivacaine 0.5% + Epinephrine (1:200,000)
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Lalonde, Donald H., M.D.
Laparoscopic Surgical Procedure, Nerve Block
Laparoscopic vs Ultrasound Guided TAP Block in Colorectal Surgery. A Randomised Controlled Study.
A randomized clinical trial aiming to compare two different techniques of performing a nerve blockage of the abdominal wall. When performing surgery on the colon and rectum surgeons often use a minimal invasive technique called…
- Trial name
- LAPTAP (NCT04907461)
- Testing
- LAPTAP
- Where
- Sweden
- Volunteers
- 175 people
- Sponsor
- Danderyd Hospital
Single Traumatic Limb Injury With Severe Pain (Score > 5/10 on Numerical Pain Scale)
Intranasal Sufentanil Pain-management at Entrance of Emergency Department : Influence on Pain-relief Delay
Non-invasive and simple, intranasal (IN) route of administration seems promising for pain management in the Emergency Department (ED), especially when used precociously by triage nurse to rapidly deliver the first opioid dose to…
- Trial name
- InSPEED (NCT01954368)
- Testing
- Sufentanil
- Where
- France
- Volunteers
- 144 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Low Back Pain, Vertebrogenic Pain Syndrome
Time to BBVNA Relief
Basivertebral nerve ablation (BVNA) is a minimally invasive procedure approved for vertebrogenic low back pain. While early studies support its efficacy, real-world evidence is still evolving, particularly regarding the…
- Conditions
- Low Back Pain, Vertebrogenic Pain Syndrome, Basivertebral Nerve Ablation
- Trial name
- NCT07433634
- Testing
- Basivertebral nerve ablation
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Yale University
Breast Carcinoma, Kidney Carcinoma
Functional Near-Infrared Spectroscopy and Virtual Reality Relaxation Programs for Pain Management in Patients With Cancer
This study aims to develop objective tools for assessing perceived pain severity in cancer patients and survivors, evaluate the sustained effectiveness of non-pharmacological interventions such as virtual reality in reducing pain…
- Conditions
- Breast Carcinoma, Kidney Carcinoma, Carcinoma
- Trial name
- NCT06456411
- Testing
- Functional Near-Infrared Spectroscopy, Questionnaire Administration, Virtual Technology Intervention
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Pain
TENS and Heat for Reducing Back Pain in Humans
Lower back pain is one of the most common and most expensive impairments costing time and expense in the work force today. With the effects on cognitive skills and addictive side effects of opioids and other prescription pain…
- Trial name
- NCT03740750
- Testing
- Thermacare heat wraps, TENS
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Future Sciene Technology
Post-Herpetic Neuralgia
Study of Pregabalin Therapy for Pain Relief in Subjects With Post-Herpetic Neuralgia
The purpose of this study is to measure how rapidly pregabalin treatment can relieve pain in patients with post-herpetic neuralgia
- Trial name
- NCT00159666
- Testing
- pregabalin
- Where
- 40 sites in United States, Germany and 3 more
- Volunteers
- 255 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pharyngitis
Evaluate the Time of Pain Relief of Fast Acting Aspirin Versus Acetaminophen in Subjects Diagnosed With Sore Throat Pain
This study is to evaluate the onset of relief provided by a single, oral dose of fast release aspirin 1000 mg compared to acetaminophen 1000 mg and placebo in subjects with sore throat pain.
- Trial name
- Tarot (NCT01453400)
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Bayer
Chronic Pain
Elosan Efficacy Study (EES)
The "Elosan Cabin" is a closed, electrically insulated, biocompatible cabin for the short-term application of electrostatic high voltage in patients with chronic pain, especially those with rheumatic diseases.
- Trial name
- NCT03823729
- Testing
- Elosan Cabin
- Where
- 3 sites in Switzerland
- Volunteers
- 39 people
- Sponsor
- Elosan AG
Hip Osteoarthritis, Hip Arthroplasty Replacement
Post-Operative Spinal Block Duration and Pain Relief After Hip Replacement Surgery: Comparing Single-Shot Spinal Ropivacaine and Bupivacaine
This study aims to determine whether isobaric ropivacaine is more suitable than isobaric bupivacaine for spinal anesthesia in outpatient total hip arthroplasty (THA).
- Conditions
- Hip Osteoarthritis, Hip Arthroplasty Replacement, Postoperative Pain After Ambulatory Surgery
- Trial name
- ROBUTHA (NCT07631091)
- Testing
- Spinal Anesthesia with Ropivacaine 15 mg (5 mg/ml), Spinal Anesthesia with Bupivacaine 11 mg (5 mg/ml)
- Volunteers
- 176 people
- Sponsor
- University of Turku
Low Back Pain, Lumbar Disc Herniation
Efficacy and Duration of Pain Relief in Transforaminal and Lumbar Sympathetic Blocks
Low back pain is a symptom that is frequently seen in the general population and reduces the quality of life of patients. Conventional medical treatment for patients with low back pain includes oral medication, lifestyle…
- Trial name
- NCT06438952
- Testing
- Transforaminal steroid injection combined with lumbar sympathetic blockade, Transforaminal steroid injection only
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Bezmialem Vakif University
Postoperative Pain
Efficacy of Fentanyl to Reduce the Time of Severe Postoperative Pain Relief Compared to Morphine
Fentanyl is a potent opioid, it is theoretically 100 times more potent that morphine and in severe acute postoperative pain acts faster than its congener (morphine ) for pain relief .
- Trial name
- NCT02145975
- Testing
- Fentanyl, Morphine
- Where
- Colombia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Duration of Pain Relief
Effect of Dexamethasone on Duration of Lower Extremity Blocks With Bupivacaine in Subjects Having ACL Repair
Anterior cruciate ligament reapair is a painful procedure. Single shot femoral and sciatic nerve block only last 12-16 hrs. Since dexamethasone prolongs brachial plexus block, using it in lower extremity blocks will prolong the…
- Trial name
- NCT01756560
- Testing
- dexamethsone, Bupivacaine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Chicago