Clinical trials: Dysfunctional Labor
Dystocia
The Study of Giving Birth, a Study About Treatment of Labor Dystocia
Labor dystocia is an intransigent, high-profile issue in obstetric care, which causes significant maternal morbidity in low resource settings and maternal dissatisfaction, and increased healthcare costs worldwide.
- Trial name
- GB (NCT04649593)
- Testing
- Samarin
- Where
- Sweden
- Volunteers
- 2,000 people
- Sponsor
- Karolinska Institutet
Pregnancy, Uterine Contraction
Calcium Carbonate on Labor Induction
The investigators aim to evaluate the safety and efficacy of administering calcium carbonate to laboring participants undergoing labor inductions.
- Trial name
- NCT06352775
- Testing
- Calcium Carbonate
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Wake Forest University Health Sciences
Postpartum Hemorrhage
Administration Of Calcium Gluconate for The Reduction of Blood Loss During Vaginal Delivery
Postpartum hemorrhage is one of the leading causes of maternal morbidity following childbirth. Even when excessive bleeding is not clinically recognized, some women experience a significant decrease in hemoglobin levels after…
- Trial name
- NCT07714902
- Testing
- calcium gluconate
- Where
- Israel
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Uterine Atony With Hemorrhage
Multimodal Uterotonics at the Time of Cesarean Section in Laboring Patients
Postpartum hemorrhage remains a leading cause of maternal morbidity and mortality worldwide, even in high income countries. Uterine atony is estimated to cause 70-80% of postpartum hemorrhage.
- Trial name
- NCT03904446
- Testing
- Methylergonovine
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Cynthia Wong
Delivery Problem, Childrearing
Perineal Massage Performed During the Labour
In this study, perineal massage was applied to primiparous women who did not give birth before, as a quasi-experimental control group to determine the effects of massage on birth comfort, perineal trauma and perineal pain.
- Conditions
- Delivery Problem, Childrearing, Satisfaction, Patient, Perineum; Injury
- Trial name
- NCT05962918
- Testing
- Perinal massage
- Where
- Turkey (Türkiye)
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Munzur University
Labor (Obstetrics)--Complications, Labor; Dyscoordinate
Biomarkers of Uterine Muscle Physiology
This observational study characterizes the relationship between amniotic fluid lactate and uterine electromyography during labor in healthy individuals at term planning a vaginal birth.
- Trial name
- BUMP (NCT04251702)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Postpartum Hemorrhage, Uterine Atony
Balloon Tamponade Versus Gauze Packing for Postpartum Hemorrhage
Postpartum hemorrhage due to uterine atony is a major cause of maternal morbidity and mortality. This randomized controlled trial aims to compare the efficacy of uterine balloon tamponade and uterine gauze packing in controlling…
- Trial name
- NCT07609589
- Testing
- Uterine Balloon Tamponade, Uterine gauze packing
- Volunteers
- 216 people
- Sponsor
- Khyber Teaching Hospital
Dystocia
Comparison of Low-dose and High-dose Oxytocin Regimens for Labor Augmentation
Oxytocin is a medication that is often used to strengthen contractions to overcome delayed labor progress. The primary aim of this study is to determine whether receiving a higher dose of oxytocin lowers the chance of needing a…
- Trial name
- NCT02487797
- Testing
- Oxytocin, Sodium Chloride 0.9%
- Where
- United States
- Volunteers
- 1,003 people
- Sponsor
- Northwestern University
Pregnancy Complications Nos, Labor/Delivery Problems Nos
Early Postnatal Discharge in a French Perinatal Network
The purpose of this "before-after" study is to determine the effectiveness of a multidimensional intervention to increase the rate for early discharge of low-risk mothers and the healthy newborn in a perinatal network.
- Conditions
- Pregnancy Complications Nos, Labor/Delivery Problems Nos, Vitality; Newborn
- Trial name
- SORPRISE (NCT02298569)
- Testing
- multi-pronged program to improve early postpartum discharge
- Where
- 5 sites in France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Grenoble
Postpartum Hemorrhage
Prediction of Uterine Atony After Vaginal Delivery by Elastography
Prospective study evaluating the feasibility of shear-wave elastography of the uterus during the third stage of labour and following placental delivery.
- Trial name
- NCT04267783
- Testing
- Shear wave elastography
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Dystocia
Use of Acupuncture for Stimulation of Labour
Hypothesis:Acupuncture can be used as stimulation of labour in case of primary og secondary inertia. A randomized controlled trial including 150 pregnant women Acupuncture has become a natural part of the range of obstetric…
- Trial name
- NCT00279071
- Testing
- Acupuncture og acupressure when diagnosed with dystocia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Herning Hospital
Labor Long, Labour;Obstructed
Biofeedback for Second Stage of Labor
The purpose of this study is to examine whether transperineal ultrasound as visual biofeedback can be used during labor as an effective tool for shortening the second stage of labor and reducing the need for instrumental…
- Trial name
- NCT04210908
- Testing
- Visual biofeedback
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Obstructed Labor
Use of Preoperative Sodium Bicarbonate Among Women With Obstructed Labor
The goal of this clinical trial is to determine a universal safe and effective dose of sodium bicarbonate for use among women with Obstructed labour to treat acidosis.
- Trial name
- SoBicOL-II (NCT06579690)
- Testing
- 8.4% sodium bicarbonate solution, 0.9% Normal Saline
- Where
- Uganda
- Volunteers
- 472 people
- Sponsor
- Busitema University
Cesarean Delivery Affecting Fetus, Labor Dystocia
Early Diagnosis and Intervention for Fetal Malposition in Active Labor and Its Impact on Mode of Delivery
The goal of this randomized trial is to test if changing a person's position in labor can increase the chances of delivering their baby vaginally.
- Conditions
- Cesarean Delivery Affecting Fetus, Labor Dystocia, Labor Complication
- Trial name
- NCT05881629
- Testing
- Maternal position change to side-lying lateral with peanut ball, Free maternal position
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Humerus Fractures
Serum-Protein-Based Indices for the Progression of Fracture Healing and Nonunion
To define a serum protein-based diagnostic for the progression and failure of fracture healing, through the identification of a set of serum proteins that appear at early times of biological healing and show a specific…
- Trial name
- UNION (NCT05143476)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Major Extremity Trauma Research Consortium
Dystocia
Labor Scale Versus WHO Partograph for Management of Labor (ScaLP)
The current study aims at evaluating the impact of the implementation of the labor scale, in comparison to the standard WHO partograph, in the management of primiparous women, including CD rate, maternal and neonatal outcomes of…
- Trial name
- ScaLP (NCT05341076)
- Testing
- Amniotomy, Oxytocin, Cesarean Section
- Where
- Egypt
- Volunteers
- 206 people
- Sponsor
- Assiut University
Sudden Unexplained Infant Death, Apnea of Newborn
Advanced Wireless Sensors for Neonatal Care in the Delivery Room
The goals of this observational study is to assess whether a new advanced wireless skin sensor vital sign monitoring system can effectively monitor the vital signs of healthy newborn infants (≥ 35 weeks gestational age).
- Conditions
- Sudden Unexplained Infant Death, Apnea of Newborn, Newborn Morbidity, Newborn Asphyxia
- Trial name
- AWARD (NCT06693817)
- Testing
- Wireless skin sensors vital sign monitoring system, Wired vital sign monitoring system
- Where
- 5 sites in Brazil, Canada and 2 more
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Guilherme Sant'Anna, MD
Dystocia
A Comparative Study of the Effect of Two Partographs on the Cesarean Section Rate in Women in Spontaneous Labour
In the 2010-french perinatal survey, the overall cesarean section (CS) rate during labour was 21 % and 16% to 38% in case of dystocia.
- Trial name
- PARTODYS (NCT02741141)
- Testing
- New partograph based on the studies of Neal and Lowe, Classical partograph
- Where
- France
- Volunteers
- 633 people
- Sponsor
- University Hospital, Strasbourg, France
Shoulder Dystocia
Investigation of the Effect of Different Training Techniques in Teaching the Management of Shoulder Dystocia
In this study, it was aimed to determine the effect of demonstration, telesimulation and game-based teaching on teaching shoulder dystocia management in midwifery students.
- Trial name
- NCT05660551
- Testing
- Demostration, Telesimulation, Kahoot Game
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Ankara University
Postpartum Hemorrhage, Uterine Atony
Second-Line Uterotonics in Postpartum Hemorrhage: A Randomized Clinical Trial
The aim of this study is to evaluate in a randomized fashion the comparative efficacy of two second-line medications, methylergonovine and carboprost for treating atonic postpartum hemorrhage (PPH).
- Trial name
- NCT03584854
- Testing
- 15-methyl prostaglandin F2α, Methylergonovine Maleate
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital