Clinical trials: Dysfunctional Labor
Labor Dystocia, Labor Induction
Calcium Carbonate to Augment Labor Contractions
The investigators think that calcium carbonate can act as an assistive medication to improve contractions during labor.
- Conditions
- Labor Dystocia, Labor Induction, Labor Augmentation
- Trial name
- CALC (NCT06580782)
- Testing
- Calcium Carbonate 500 MG, Standard Dose Synthetic Pitocin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Postpartum Hemorrhage, Uterine Atony
Does Intramyometrial Oxytocin Improve Outcome in Elective Cesarean Delivery?
Oxytocin use has become routine practice in elective cesarean delivery to promote uterine contraction and reduce blood loss. However, there is a lack of consensus regarding the best dose of oxytocin and the most effective route…
- Trial name
- NCT01252342
- Testing
- Oxytocin, Saline
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Postpartum Haemorrhage (PPH)
Temporary Aortic Occlusion With the Abdominal Tourniquet for Refractory Postpartum Haemorrhage: A Proof-of-Concept Study in a War-Affected Region
The purpose of this study is to evaluate whether a medical device called the Abdominal Aortic and Junctional Tourniquet - Stabilized (AAJT-S) can safely and effectively temporarily stop severe bleeding after childbirth (known as…
- Trial name
- TAOAT (NCT07016568)
- Testing
- Abdominal Aortic and Junctional Tourniquet - Stabilized (AAJT-S)
- Where
- Ukraine
- Volunteers
- 4 people
- Sponsor
- LLC UkrMedGroup
Labour;Obstructed, Labor Dystocia
Propranolol for Protracted Labor
Induction of labor is one of the most common procedures performed on labor and delivery. In the United States, more than 20 percent of pregnant women undergo an induction of labor [1].
- Trial name
- PRO-Labor (NCT04741698)
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Uterine Contraction, Labor Complication
Oral Calcium Supplementation in Labor
The goal of this clinical trial is to learn if oral calcium carbonate can improve uterine contractions and labor outcomes in term pregnancies. It will also evaluate the safety of calcium carbonate when used during labor.
- Conditions
- Uterine Contraction, Labor Complication, Labor Active Dilated Cm, Labor Dystocia
- Trial name
- NCT07056062
- Testing
- Calcium carbonate
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Arrowhead Regional Medical Center
Labor
A Study on the Effects of Dextrose Solutions on the Course of Labor
The purpose is to determine in term nulliparas with singletons that present in active labor (3-5 cm) or with ruptured membranes whether the administration of dextrose solutions to normal saline improves or expedites the course of…
- Trial name
- NCT00569439
- Testing
- D5NS, D10NS, NS
- Volunteers
- 301 people
- Sponsor
- MemorialCare
Dystocia
Push With Lower Uterine Segment Support
The study aims to compare maternal and early neonatal outcomes of abdominal disimpaction with lower uterine segment support in comparison to the classic "push" method for delivery of impacted fetal head during Cesarean section…
- Trial name
- PLUS (NCT02934516)
- Testing
- Cesarean section
- Volunteers
- 66 people
- Sponsor
- Assiut University
Postpartum Hemorrhage
Comparison of IV Ergonovine With IM Carboprost, With Oxytocin IV, During Cesarean Section for Failure to Progress
Patients having Cesarean section after they have been in labor for many hours bleed much more, in average twice as much, as compared with patients having an elective Cesarean section.
- Trial name
- NCT01869556
- Testing
- Oxytocin, Ergot, Carboprost
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Hemorrhage of Cesarean Section and/or Perineal Wound, Postpartum Hemorrhage
Role of Tranexamic Acid Versus Uterine Cooling at Caesarean Section
This study aims to compare role of a prophylactic predefined intravenous Tranexamic Acid dose versus intraoperative Uterine Cooling in reducing blood loss and incidence of postpartum hemorrhage at secondary CS.
- Conditions
- Hemorrhage of Cesarean Section and/or Perineal Wound, Postpartum Hemorrhage, Uterine Atony
- Trial name
- NCT02780245
- Testing
- Tranexamic Acid, Intraoperative Uterine Cooling
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Talkha Central Hospital
Labour Dystocia
Implementation of AFL Monitoring in Clinical Use
The overall objective of this randomized controlled trial is to develop a clinical standard procedure for measuring lactate in amniotic fluid (amniotic fluid lactate = = AFL) during childbirth before oxytocin stimulation is…
- Trial name
- NCT03650972
- Testing
- Samarin
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Cervical Dystocia
Randomised Controlled Trial of the Efficacy of Acupuncture Versus Placebo on the Caesarean Section Rate in Case of Cervical Dystocia in Full-term Pregnancy
The principal objective of the trial is to demonstrate that acupuncture could reduce the caesarean section rate for cervical dystocia.
- Trial name
- ACUCESAR (NCT02394041)
- Testing
- Acupuncture
- Where
- France
- Volunteers
- 142 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Blood Loss, Surgical, Blood Loss, Postoperative
Prophylactic Intravenous Calcium Gluconate to Decrease Blood Loss at Time of Cesarean Delivery in Pregnant Patients at High Risk for Uterine Atony
This research study is being done to learn what effect a single dose of calcium gluconate will have on blood loss at the time of cesarean delivery in pregnancy patients at high risk for uterine atony.
- Conditions
- Blood Loss, Surgical, Blood Loss, Postoperative, Uterine Atony
- Trial name
- NCT07217899
- Testing
- Calcium Gluconate, Saline
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Michigan
Cesarean Section Complications, Postpartum Hemorrhage
The Comparison of the Effect of Different Oxytocin Administrations on the Blood Loss During Cesarean Delivery
This study compares the effect of starting intravenous oxytocin infusion early before uterine incision versus late after umbilical cord clamping on the blood loss during elective cesarean section
- Conditions
- Cesarean Section Complications, Postpartum Hemorrhage, Blood Loss, Surgical, Blood Loss, Postoperative
- Trial name
- NCT03967171
- Testing
- before uterine incision oxytocin, after clamping the umbilical cord oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Postpartum Hemorrhage
Treatment of Postpartum Hemorrhage With Misoprostol: Fever Study
This study seeks to assess whether populations of women in Latin America outside Quito, Ecuador are at increased risk for developing elevated body temperature above 40.0°C following PPH treatment with 800mcg sublingual…
- Trial name
- NCT02163616
- Testing
- Misoprostol
- Where
- 2 sites in Argentina
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abnormal Labor, Complication of Delivery
Clinical Application of Intrapartum Ultrasound
Intrapartum ultrasound monitoring is to be compared with conventional labor monitoring to clarify the accuracy of this technology, and then provide a basis for later related research.
- Trial name
- IPUS (NCT06442735)
- Testing
- intrapartum ultrasound, vaginal examination
- Where
- China
- Volunteers
- 455 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Macrosomia, Induction of Labor
Induction of Labor Versus Expectant Management of Large for Gestational Age/Macrosomic Babies at Term. A Multi-center Trial
The equipoise whether to Induce pregnant women with suspected large for gestational babies or suspected macrosomia babies at term pregnancy is not solved yet.
- Conditions
- Macrosomia, Induction of Labor, Expectant Management, Shoulder Dystocia
- Trial name
- IOLEMMT (NCT02315820)
- Testing
- Induction of labor group (Group I)
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya