Clinical trials: Dystonic Tremor
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Dystonic Tremor Syndrome
Factors Determining the Efficacy of Botulinum Toxin for Arm Tremor in Dystonia
Tremor occurs in up to 55% of dystonia patients, which is known as dystonic tremor syndrome (DTS). Tremor can be present in the body part affected by dystonia (dystonic tremor, DT), or an unaffected body part (tremor associated…
- Trial name
- BAT (NCT06411028)
- Testing
- Polymyography, Muscle ultrasound, (Functional) magnetic resonance imaging
- Where
- 3 sites in Netherlands
- Volunteers
- 60 people
- Sponsor
- Radboud University Medical Center
Essential Tremor, Parkinson's Disease (PD)
Attention and Eye Movement in Parkinson's Disease
The goal of this observational and interventional study is to understand how therapeutic deep brain stimulation (DBS) affects attention, perception and cognition in participants with Parkinson's disease (PD) and non-PD movement…
- Conditions
- Essential Tremor, Parkinson's Disease (PD), Dystonias
- Trial name
- NCT06899022
- Testing
- Normal therapeutic DBS, Reduced current DBS, Reduced frequency DBS
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Aneurysms, Arteriovenous Malformations
Neurosurgical Outcome Network
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared.
- Conditions
- Aneurysms, Arteriovenous Malformations, Cavernomas, Skull Base Tumors
- Trial name
- NEON (NCT06724029)
- Where
- 27 sites in Italy
- Volunteers
- 4,500 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Movement Disorders, Parkinson Disease
Abbott DBS Post-Market Study of Outcomes for Indications Over Time
The purpose of this international study is to evaluate long-term safety and effectiveness of Abbott deep brain stimulation (DBS) systems for all indications, including Parkinson's disease, essential tremor or other disabling…
- Conditions
- Movement Disorders, Parkinson Disease, Essential Tremor, Tremor
- Trial name
- ADROIT (NCT04071847)
- Testing
- Deep Brain Stimulation (DBS)
- Where
- 48 sites in United States, Australia and 7 more
- Volunteers
- 1,000 people
- Sponsor
- Abbott Medical Devices
Essential Tremor, Dystonic Tremor
VIM DBS Respiratory Modulation: N-of-1 Trial
Research from our group has demonstrated modulation of PEFR in patients with STN and PAG stimulation. However, the effect of VIM (motor thalamus) stimulation remains to be investigated.
- Trial name
- NCT05381688
- Testing
- VIM DBS
- Sponsor
- University of Oxford
Ataxia - Other, Dystonia Disorder
Stimulation of the Dentate Nucleus of the Cerebellum for the Treatment of Refractory Spasticity With or Without Dystonia
Electrical stimulation (DBS) through electrodes implanted in the dentate nucleus of the cerebellum for the treatment of tremor intractable with medication, dystonia due to cerebrovascular disease (stroke), sequelae of traumatic…
- Conditions
- Ataxia - Other, Dystonia Disorder, Tremor, Essential, Choreatic Disorder
- Trial name
- DN_DBS (NCT07231302)
- Testing
- Analytical observation
- Volunteers
- 20 people
- Sponsor
- Kleber Paiva Duarte
Parkinson Disease (PD), Essential Tremor
Modulate Tremor Severity With Low-intensity Focused Ultrasound Stimulation Targeting the Deep Nucleus of Patients With Refractory Hand Tremor.
The study plans to recruit 12 patients with Parkinsonian tremor, essential tremor, or dystonic tremor. After receiving NaviFUS-ctbTUS stimulation, the improvement in their tremor will be recorded.
- Conditions
- Parkinson Disease (PD), Essential Tremor, Dystonic Tremor, Continuous Theta Burst Stimulation Transcranial Focused Ultrasound
- Trial name
- NCT07172295
- Testing
- Accelerated NaviFUS-ctbFUS stimulation
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- National Taiwan University Hospital
Dystonic Tremor
PSA Versus STN DBS for DT
The aim of this study is to compare the effectiveness of the deep brain stimulation in the posterior subthalamic area (PSA) versus the subthalamic nucleus (STN) for the treatment of dystonic tremor (DT) in a randomized…
- Trial name
- PSA-STN (NCT06752434)
- Testing
- Deep brain stimulation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Ruijin Hospital
Essential Tremor, Parkinson Disease
Using Wearable and Mobile Data to Diagnose and Monitor Movement Disorders
The purpose of the research is to better understand the motor behavior of individuals in health and disease. The specific purpose of this project is to identify if we can utilize a smartphone to diagnose different movement…
- Conditions
- Essential Tremor, Parkinson Disease, Huntington Disease, Dystonia, Primary
- Trial name
- NCT04231487
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Rutgers, The State University of New Jersey
Spasticity, Focal Dystonia
Compare Two Guidance Techniques for Botulinum Toxin Injections for the Treatment of Limb Spasticity and Focal Dystonia
This study seeks to compare the use of ultrasound and electrophysiologic techniques to target muscles for the treatment of spasticity and focal dystonia of the limbs.
- Conditions
- Spasticity, Focal Dystonia, Tremor, Limb
- Trial name
- NCT02334683
- Testing
- Electrical stimulation, Ultrasound
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Parkinson Disease, Tremor, Essential
Effectiveness and Reliability of Hypnosis in Stereotaxy
In certain neurosurgical procedures, the use of a stereotaxic frame is required. It is then possible to set a precise target (depending of the type of the surgery) to be reached by the surgeon.
- Conditions
- Parkinson Disease, Tremor, Essential, Dystonia, Primary
- Trial name
- ERST (NCT03074422)
- Testing
- Hypnosis
- Where
- Switzerland
- Volunteers
- 22 people
- Sponsor
- University Hospital, Geneva
Essential Tremor, Cervical Dystonia
Neurophysiologic Study of Patient With Essential Tremor and Dystonic Tremor
Background: Essential tremor is when a person has tremor, but no other neurological symptoms. Dystonic tremor is when a person also has dystonia. Dystonia is a condition in which muscle contraction causes changes in posture.
- Conditions
- Essential Tremor, Cervical Dystonia, Focal Dystonia
- Trial name
- NCT03041714
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Focal Dystonia
Quantifying Musical Performance After Treatment With Myobloc in Musician's Dystonia
This study uses a computerized method of musical instrument digital interface (MIDI) quantification of performance before and after treatment with botulinum toxin type B (Myobloc ®, Solstice Neurosciences).
- Trial name
- NCT00208091
- Testing
- Botulinum toxin, type B
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Columbia University