Clinical trials: EUS
Non-alcoholic Fatty Liver Disease, Nonalcoholic Steatohepatitis
Endoscopic Ultrasound(EUS)-Guided TRUCUT Biopsy (EUS-TCB) of Suspected Nonalcoholic Fatty Liver Disease(NAFLD.)
Endoscopic Ultrasound involves the placement of a small flexible camera through the mouth and into the stomach to image various parts of the body.
- Trial name
- NAFLD (NCT00586313)
- Testing
- Tru-cut biopsy, Tru-cut
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Indiana University
Pancreatic Cancer, Lymphadenopathy
Prospective Trial of EUS-FNA Versus EUS-FNB Using a Novel Core Biopsy Needle
Endoscopic ultrasound (EUS) is paramount in the diagnosis and evaluation of cancers involving the gastrointestinal tract. EUS allows for the acquisition of cellular (fine needle aspirate - FNA) or tissue biopsy (fine needle…
- Conditions
- Pancreatic Cancer, Lymphadenopathy, Gastrointestinal Stromal Tumor
- Trial name
- MUCIN (NCT01769248)
- Testing
- Fine needle aspiration, Fine needle biopsy
- Where
- 3 sites in United States
- Volunteers
- 140 people
- Sponsor
- Northwestern University
Hypoxemia
Does Capnography Prevent Hypoxemia During Endoscopic Retrograde Cholangiopancreatography and Endoscopic Ultrasound?
Subjects undergoing elective ERCP and EUS will receive standard monitoring and sedation. In addition, capnography which measures carbon dioxide levels and can graphically assess respiratory activity will be used.
- Trial name
- NCT00675415
- Testing
- Capnography
- Where
- United States
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Pancreatic Adenocarcinoma
The Impact Of Tissue Micro-RNA Profile From EUS-FNA In Pancreatic Adenocarcinoma
Pancreatic adenocarcinoma still represents one of the "hot-topics" worldwide. Endoscopic ultrasonography was a breakthrough, bringing us closer to personalized treatment by getting histopathological samples through…
- Trial name
- EUS-FNA (NCT04765410)
- Testing
- EUS FNA (endoscopic ultrasound fine needle aspiration)
- Where
- 5 sites in Romania
- Volunteers
- 57 people
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Pancreatic Cysts
Endoscopic Abraxane Injection Into Pancreatic Cysts
This research study is a pilot study. In this pilot study we are testing the safety of a procedure. "Investigational" means that the Albumin bound paclitaxel (Abraxane) is still being studied and that research doctors are trying…
- Trial name
- NCT01698710
- Testing
- Albumin bound paclitaxel
- Volunteers
- 5 people
- Sponsor
- Massachusetts General Hospital
Pancreatic Cancer
Talimogene Laherparepvec in Patients With Unresectable Pancreatic Cancer
The purpose of the study is to assess the safety of injections of talimogene laherparepvec into patients with pancreatic cancer that cannot be removed by surgery.
- Trial name
- NCT00402025
- Testing
- Talimogene Laherparepvec
- Where
- 3 sites in United States
- Volunteers
- 17 people
- Sponsor
- BioVex Limited
Pancreatic Cysts
A Pilot Study on the Use of Prophylactic Antibiotics for EUS-guided Pancreatic Cyst Aspiration
Our hypothesis is that a single dose of antibiotics at time of EUS-guided pancreatic cyst aspiration is equally effective to the usual regimen of 3 days of post-procedural antibiotics.
- Trial name
- NCT01929460
- Testing
- Ciprofloxacin
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Kaiser Permanente
Pancreatic Cysts
Prevalence of Pancreatic Cysts During Routine Endoscopic Ultra Sound
The investigators are interested in performing a detailed examination of the pancreas via EUS (Endoscopic Ultra Sound)for patients referred for a non-pancreatic condition.
- Trial name
- NCT01624363
- Where
- United States
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- Indiana University
Pancreatic Cysts
In Vivo nCLE Study in the Pancreas With Endosonography of Cystic Tumors
Assess the safety and efficacy of the Cellvizio needle-based Confocal Laser Endomicroscopy (nCLE) system in differentiating benign from malignant and premalignant cysts (e.g. mucinous from non-mucinous cysts)
- Trial name
- INSPECT (NCT01236300)
- Testing
- Cellvizio needle-based Confocal Laser Endomicroscopy (nCLE) system
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Chicago
Cancer of Pancreas, Pancreatic Neoplasm
Trial Comparing 19 and 25-gauge EUS-FNA Needles
This study compares the 19G and 25G needles for procuring tissue samples from the pancreas during Endoscopic Ultrasound (EUS) procedures.
- Trial name
- EUS-FNA (NCT01677312)
- Testing
- Pancreatic Biopsy, Histological Samples
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- AdventHealth
EUS Guided Biopsy
SharkCore Versus Acquire FNB
Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) has been established as an effective technique for sampling tissue inside and around the gastrointestinal tract, including the pancreas, liver, lymph nodes, and…
- Trial name
- NCT03672032
- Testing
- Fork-tip Needle, Franseen Needle
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Henning Gerke
Endoscopic Ultrasound (EUS), Endoscopic Retrograde Cholangiopancreatography (ERCP)
Adjunct Sedatives in Endoscopic Ultrasound (EUS) and Endoscopic Retrograde Cholangiopancreatography (ERCP) Procedures
The purpose of this study is to compare meperidine/midazolam with diphenhydramine, meperidine/midazolam with promethazine, and meperidine/midazolam with placebo as sedation methods.
- Trial name
- NCT00937924
- Testing
- Meperidine, Midazolam, Diphenhydramine, Promethazine
- Where
- United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Solid Tumor
Comparison of Three Tissue Acquiring Techniques During EUS Guided Biopsies of Solid Tumors.
The study's aim is to prospectively compare three different tissue acquisition techniques during EUS guided solid lesions biopsies.
- Trial name
- NCT03264092
- Testing
- Endoscopic ultrasound guided fine needle biopsy
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Liver Diseases
Benign Liver Optimal Core Study (Tissue Acquisition Comparison in Benign Liver Disease)
The primary purpose of this prospective, randomized, multicenter study is to evaluate and compare the amount and quality of tissue samples yielded in a liver biopsy comparing 2 different techniques of EUS guided CORE liver biopsy…
- Trial name
- BLOCS (NCT03245580)
- Testing
- Core Liver Biopsy
- Where
- 7 sites in United States
- Volunteers
- 153 people
- Sponsor
- Parkview Health
Chronic Pancreatitis
CPB Versus Sham Treatment for Pain Management in Small Duct Chronic Pancreatitis
This study assesses the pain response to Endoscopic Ultrasound (EUS) guided Celiac Plexus Block (CPB) treatment in comparison to EUS without a pain block administered. All participants will receive medications for pain as needed.
- Trial name
- NCT02054910
- Testing
- Celiac Plexus Block
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Alabama at Birmingham
Walled Off Pancreatic Necrosis
AXIOS Lumen Apposing Metal Stent for Walled Off Necrosis Drainage IDE Study
To demonstrate safety and effectiveness of lumen-apposing metal stents for resolution of walled off pancreatic necrosis (WONs) in patients with WONs with solid component >30%.
- Trial name
- NCT03525808
- Testing
- AXIOS
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Boston Scientific Corporation
Pancreatic Cancer
Endoscopic Ultrasound (EUS) Guided Fine Needle Aspiration (FNA) EUS-FNA of Solid Pancreatic Mass Lesions Using a Novel Corkscrew Technique: a Pilot Study
This research is being done to investigate if a new technique to biopsy the pancreas will lead to a larger amount tissue material that can be analyzed.
- Trial name
- NCT02116322
- Testing
- EUS-FNA with Corkscrew technique, Expect 19 G Flex needle
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Johns Hopkins University
Biopsy, Fine-Needle, Biopsy, Fine-Needle/Methods
EUS-guided Fine Needle Aspiration (FNA) With and Without the Use of a Stylet
The purpose of this study is to determine that there is no difference in final diagnosis of FNA specimens without a stylet, compared to using a stylet, when examined by a skilled cytopathologist.
- Conditions
- Biopsy, Fine-Needle, Biopsy, Fine-Needle/Methods, Endosonography
- Trial name
- NCT01316614
- Testing
- FNA with and without a stylet
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Washington University School of Medicine
Pancreatic Cancer
Comparison of Back-loaded vs Preloaded Fiducial Needles in EUS-guided Fiducial Marker Placement in Pancreatic Cancer.
Endoscopic ultrasound (EUS) has been pivotal in accomplishing image guided radiation therapy (IGRT) in patients with pancreatic cancer by allowing precise contouring and identification of target lesions in the pancreas via…
- Trial name
- NCT02332863
- Testing
- Back-loaded Needle (Device), Preloaded Needle (Device)
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- University of Colorado, Denver
Pancreatic Masses, Lymph Nodes
Comparing a 25G EUS Fine Needle Aspiration (FNA) Device With a 20G EUS
The aim of this study is to compare the diagnostic accuracy of two EUS-guided tissue acquisition devices; the 25G Echotip Ultra Fine Needle Aspiration (FNA) device and the 20G Echotip ProCore Fine Needle Biopsy (FNB) device.
- Trial name
- ASPRO (NCT02167074)
- Testing
- 25G FNA needle, 20G ProCore FNB needle
- Where
- 13 sites in United States, Australia and 8 more
- Volunteers
- 615 people
- Sponsor
- Foundation for Liver Research