Clinical trials: EUS
Nonfunctional Pancreatic Neuroendocrine Tumor, Pancreatic Neuroendocrine Tumor
EUS-FNI for Nonfunctional Pancreatic Neuroendocrine Tumors
The current study aims to access the feasibility, safety, and efficacy of EUS-FNI for nonfunctional pNETs
- Conditions
- Nonfunctional Pancreatic Neuroendocrine Tumor, Pancreatic Neuroendocrine Tumor, Endoscopic Ultrasound
- Trial name
- NCT05566093
- Testing
- EUS-guided ethanol ablation, EUS-guided lauromacrogol ablation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Guangxi Medical University
Pancreatic Neoplasms
Randomized Trial of EUS Neurolysis in Pancreas Cancer
This is a clinical trial to determine more effective methods of controlling the pain in pancreatic cancer. Although narcotic pain medication are effective, they have many side effects and are underutilized due to social stigma…
- Trial name
- NCT00279292
- Testing
- Celiac Plexus Neurolysis
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Hepatocellular Carcinoma, Hepatoma
Accuracy of Endoscopic Ultrasound for Detection of Tumors of the Liver
The diagnostic accuracy of EUS for detection of the liver tumors (primary and metastatic) remains unknown. To compare the accuracy of the EUS and CT scan for detection of the primary and metastatic carcinoma of the liver.
- Conditions
- Hepatocellular Carcinoma, Hepatoma, Cholangiocarcinoma, Liver Metastases
- Trial name
- NCT00290316
- Testing
- Endoscopy ultrasound
- Where
- United States
- Sponsor
- Central Texas Veterans Health Care System
Solid Mass Lesions in GI Tract
Comparing the Franseen and Fork-top Needles for EUS-guided Fine-needle Biopsy of Solid Mass Lesions.
This will be a randomized controlled trial of all the patients referred to University of Arkansas Medical for Medical Sciences (UAMS) for endoscopic ultrasound (EUS) guided biopsy of solid mass lesions.
- Trial name
- NCT03561038
- Testing
- Franseen Needle, Fork-tip Needle
- Sponsor
- University of Arkansas
Pancreatic Neoplasm, Pancreatic Neuroendocrine Tumor
Endoscopic Ultrasound-Guided Pulsed Electric Field Ablation for the Treatment of Pancreatic Neoplasms
This clinical trial tests the safety and feasibility of endoscopic ultrasound-guided pulsed electric field ablation for the treatment of pancreatic neoplasms.
- Trial name
- NCT07619417
- Testing
- Clinical Intervention or Procedure, Electronic Health Record Review, Endoscopic Ultrasound-Guided Fine-Needle Aspiration of the Pancreas
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Pancreatic Pseudocyst, Drainage
Treatment of Pancreatic Pseudocysts by Endoscopic Ultrasound-guided Drainage
Patients may evolve pseudocysts of the pancreas secondary to a severe pancreatitis. In case of a symptomatic or infected pseudocyst, a therapeutic drainage of the cyst is indicated.
- Trial name
- NCT02845258
- Testing
- Pancreatic pseudocyst drainage with a plastic or self-expandable metallic stent (SEMS)
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Sahlgrenska University Hospital
Pancreatic Solid Lesions
Artificial Intelligence (AI) Cytopathology Trial
Purpose The primary objective of the study is to compare interpretation of EUS FNA/FNB samples for adequacy between ROSE and AI at bedside.
- Trial name
- NCT05018663
- Testing
- Artificial Intelligence software ROSE
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pancreatic Neoplasms
Comparison of Two Types of Biopsy Needles for EUS-FNB in Solid Pancreatobiliary Mass Lesions
EUS-guided tissue acquisition is an established modality to diagnose malignancies of the pancreas and extrahepatic bile ducts. In the recent years fine needle biopsy (FNB) needles have largely replaced fine needle aspiration…
- Trial name
- NCT04975620
- Testing
- Fine needle biopsy
- Where
- Iran
- Volunteers
- 114 people
- Sponsor
- University of Tehran
DISTAL MALIGNANT BILIARY OBSTRUCTION
Eus-giuded Biliary Drainage With Ec-lams vs ERCP as a Primary Intervention for Endoscopic Treatment of Patinets With Distal Malignant Biliary Obstruction
Endoscopic retrograde cholangiopancreatography (ERCP) is the gold standard for the management of jaundice in patients with distal malignant biliary obstruction.
- Trial name
- EUS-BD (NCT04099862)
- Testing
- ERCP, EUS-BD
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- Istituto Clinico Humanitas
Crohn Disease (CD), Cryptoglandular Perianal Fistula
A Study Comparing Transperineal Ultrasound, Magnetic Resonance Imaging, Endoscopic Ultrasound, and Examination Under Anesthesia to Detect and Classify Perianal Fistulas in Patients With Crohn's Disease or Fistulas of Unknown Cause
The goal of this study is to learn how well different imaging tests detect and describe perianal fistulas in adults with Crohn's disease or fistulas with no known cause (cryptogenic).
- Trial name
- TRANSIT CD (NCT07794410)
- Testing
- Transperineal Ultrasound (TPUS), Magnetic Resonance Imaging (MRI), Endoscopic Ultrasound (EUS)
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Asian Institute of Gastroenterology, India
Pancreatic Cyst
Evaluation of Pancreatic Cystic Lesions Via EUS-guided Fine Needle Aspiration With and Without Micro Forceps Biopsies
Pancreatic cystic lesions (PCLs) are a common incidental finding in cross sectional imaging (up to 27% on CT scan and 41% on MRI) and pose a management challenge to physicians.
- Trial name
- NCT04404101
- Testing
- 1). EUS-FNA plus MFB, 2). EUS-FNA Alone
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Colorado, Denver
Cirrhosis, Portal Hypertension
Hepatic Venous Pressure Gradient Versus Endoscopic Ultrasound-Guided Portal Pressure Gradient - Comparative Analysis (HEPCA)
The goal of this interventional trial is to compare in measuring of portal hypertension by HVPG and EUS-PPG in subject indicated to HVPG measurement.
- Conditions
- Cirrhosis, Portal Hypertension, EUS, Non-Cirrhotic Portal Hypertension
- Trial name
- HEPCA (NCT07424963)
- Testing
- Hepatic venous pressure gradient measurement, Endoscopic ultrasound-guided portal pressure gradient measurement
- Where
- 2 sites in Czechia
- Volunteers
- 40 people
- Sponsor
- Military University Hospital, Prague
Pancreatic Cyst
A Phase II Multicentre Trial of Endoscopic Ultrasound Guided Radiofrequency Ablation of Cystic Tumours of the Pancreas
Up to 13.5% of patients that undergo a magnetic resonance imaging (MRI) scan of their abdomen without pancreatic symptoms are found to have an incidental pancreatic cyst, with the frequency increasing with age.
- Trial name
- RADIOCYST01 (NCT02343692)
- Testing
- EUS guided RFA of cystic tumours of the pancreas
- Where
- 13 sites in Australia, United Kingdom
- Volunteers
- 97 people
- Sponsor
- University College, London
Endoscopic Ultrasound, Fine-needle Aspiration
Wet-suction Versus Slow-pull for EUS-FNB of Solid Lesions
A randomized cross-over study investigating the impact of two different suction techniques on histological yield and sample quality of specimens collected by endoscopic ultrasound biopsy from solid lesions using histology needles.
- Trial name
- WEST-FNB (NCT04834193)
- Testing
- Endoscopic ultrasound-guided fine-needle biopsy
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Pancreatic Steatosis, Pancreatic Cyst
Determination of Pancreatic Steatosis Prevalence and Correlation With High-risk Cyst Features
Pancreatic cancer is the fifth leading cause of cancer mortality in Hong Kong and the seventh leading cause of cancer mortality worldwide. In 2020, approximately 496000 new cases of pancreatic cancers were diagnosed globally .
- Trial name
- FPPCN (NCT05334836)
- Testing
- MRI for pancreatic fat and liver fat quantitation
- Where
- Hong Kong
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Pancreas Disease, Liver Diseases
Motorized Fine Needle Biopsy vs Standard Needles
Recent improvements in punctures techniques and needles now allow for the collection of high-quality specimens comparable to core needle biopsy.
- Trial name
- NCT06298604
- Testing
- EUS-guided standard fine needle biopsy, EUS-guided motorized fine needle biopsy
- Where
- Ecuador
- Volunteers
- 60 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Pancreatic Ductal Adenocarcinoma
Endoscopic Ultrasound Radiofrequency Ablation (EUS-RFA) of Not-resectable Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive tumors with a poor prognosis. Despite advancements in the multimodal approach, surgical resection still represents the only potentially curative…
- Trial name
- NCT04164992
- Testing
- EUSRA electrode needle connected to a radiofrequency generator (VIVA RF generator; STARmed, Seoul, S. Korea)
- Volunteers
- 15 people
- Sponsor
- Campus Bio-Medico University
Pancreatic Ductal Adenocarcinoma (PDAC)
Pancreatic Endoscopic Ultrasound-guided RadioFrequency for Inoperable Carcinoma Treatment
The purpose of this study is to evaluate whether endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) affects survival in patients with inoperable pancreatic carcinoma.
- Trial name
- PERFECT (NCT07850336)
- Testing
- Endoscopic ultrasound-guided radiofrequency ablation
- Volunteers
- 56 people
- Sponsor
- Bojan Kovacevic
Pancreas Neoplasm
Multicentered Prospective Randomized Controlled Trial For Solid Pancreatic Lesions
Endoscopic ultrasound (EUS) is an indispensable tool for tissue acquisition for pancreatic lesions. Fine needle aspiration (FNA) is once considered as the first line diagnostic method especially when rapid on-site evaluation…
- Trial name
- NCT04841616
- Testing
- Endoscopic Ultrasound -Guided Fine Needle Biopsy, Contrast-Enhanced Harmonic Endoscopic Ultrasound
- Where
- Hong Kong
- Volunteers
- 128 people
- Sponsor
- Chinese University of Hong Kong
Liver Cirrhosis
EUS-guided Versus Percutaneous Ultrasound-guided Biopsy for Parenchymal Liver Disease
Liver biopsy may be indicated in various clinical scenarios to help diagnose and manage liver diseases. Endoscopic ultrasound (EUS) liver biopsy and percutaneous USG guided liver biopsy are two methods used to obtain liver tissue…
- Trial name
- NCT06047327
- Testing
- EUS guided liver biopsy, Percutaneous Liver Biopsy
- Where
- India
- Volunteers
- 90 people
- Sponsor
- Institute of Liver and Biliary Sciences, India