Clinical trials: EUS
Cholangiocarcinoma Patients
Impact of Preoperative Endoscopic Ultrasound-guided Fine-needle Aspiration in Cholangiocarcinoma Patients
Primary objective of this study is to evaluate the number of patients with positive LN detected by EUS and precluded from further surgical interventions.
- Trial name
- NCT06534229
- Testing
- Endoscopic ultrasound-guided fine-needle aspiration
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Asian Institute of Gastroenterology, India
Sedation Complication, Endoscopic Ultrasonography
Propofol Infusion-Based Sedation on Anesthesia-Related Adverse Events in Endoscopic Ultrasonography
Endoscopic ultrasonography (EUS) is an endoscopic procedure performed to investigate conditions affecting the stomach, liver, and bile ducts, as well as for therapeutic interventions.
- Conditions
- Sedation Complication, Endoscopic Ultrasonography, Procedural Sedation
- Trial name
- NCT06389045
- Testing
- Procedural Sedation
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Samsun University
Hepatocellular Carcinoma, Variceal Bleeding
Prevention of Variceal Rebleeding by EUS-guided vs Conventional Endoscopic Therapy in Hepatocellular Carcinoma Patients
Rebleeding rate is high in hepatocellular carcinoma (HCC) patients with variceal bleeding despite conventional endoscopic therapies for esophageal and gastric varices (EV, GV).
- Trial name
- EUS-SPV (NCT05629845)
- Testing
- endoscopic ultrasound-guided therapy, conventional endoscopic therapy
- Where
- Hong Kong
- Volunteers
- 84 people
- Sponsor
- Chinese University of Hong Kong
Pancreatitis,Acute Necrotizing
Lumen Apposing Metal Stents vs Double Pigtail Stents
While the majority of patients with acute pancreatitis suffer a mild and uncomplicated course of disease, up to 20% develop a more severe course with development of pancreatic and/or peripancreatic necroses.
- Trial name
- NCT04057846
- Testing
- EUS guided transgastric drainage
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- John Gasdal Karstensen
Gastric Varix
Endoscopic Ultrasound-guided Coil With Cyanoacrylate Injection Versus Balloon-Occluded Retrograde Transvenous Obliteration in Managing Patients With Gastric Varices
Gastrointestinal bleeding is a common complication of liver cirrhosis which caused by esophageal and gastric varices. The risk of bleeding from gastric varices is relatively low.
- Trial name
- NCT05500625
- Testing
- Endoscopic ultrasound-guided coil embolization combined with endoscopic cyanoacrylate injection, Ballon-occluded retrograde transvenous obliteration
- Volunteers
- 70 people
- Sponsor
- Assiut University
Pancreas Necrosis, Pancreatic Collection
EUS-guided Transmural Drainage of Walled-off Pancreatic Necrosis: Plastic vs Metallic Protesis.
Randomized multicenter study comparing plastic stents and self-expanding metallic stents in the eus-guided transmural drainage of walled-off pancreatic necrosis.
- Trial name
- PROMETHEUS (NCT03100578)
- Testing
- WOPN TRANSMURAL DRAINAGE: PLASTIC STENT, WOPN TRANSMURAL DRAINAGE: METALLIC STENT
- Where
- 8 sites in Spain
- Volunteers
- 99 people
- Sponsor
- Hospital Universitari de Bellvitge
Pancreatic Ductal Adenocarcinoma, Pancreatitis, Chronic
Artificial Intelligence in EUS for Diagnosing Pancreatic Solid Lesions
We aim to develop an EUS-AI model which can facilitate clinical diagnosis by analyzing EUS pictures and clinical parameters of patients.
- Conditions
- Pancreatic Ductal Adenocarcinoma, Pancreatitis, Chronic, Pancreatic Neuroendocrine Tumor, Autoimmune Pancreatitis
- Trial name
- NCT05476978
- Testing
- EUS-AI model
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Huazhong University of Science and Technology
Pancreaticobiliary Cancers, Jaundice
Endoscopic Ultrasound Versus Endoscopic Retrograde Cholangiopancreatography (ERCP) Tissue Sampling for the Diagnosis of Suspected Pancreatico-Biliary Cancer
The two most commonly used methods to biopsy suspected pancreaticobiliary masses are (1) endoscopic ultrasound guided fine-needle aspiration (EUS-FNA) and (2) cytology brush biopsies obtained during endoscopic retrograde…
- Conditions
- Pancreaticobiliary Cancers, Jaundice, Bile Duct Obstruction
- Trial name
- NCT01356030
- Testing
- ERCP, EUS FNA
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- California Pacific Medical Center Research Institute
Neoplasms
The Use of FNA and FNB in the Optimization of EUS-assisted Tissue Sampling
Endoscopic ultrasound (EUS) with fine needle aspiration (FNA) for cytology and/or fine needle biopsy (FNB) for histology may be used in the diagnostic work-up of intrathoracic and intrabdominal lesion of unknown origin.
- Trial name
- NCT02360839
- Testing
- EUS-guided fine needle biopsy sampling (EUS-FNB)
- Where
- Sweden
- Volunteers
- 1,000 people
- Sponsor
- Per Hedenström
Acute Cholecystitis
One-year Outcomes by Index Treatment in Elderly Patients With Acute Cholecystitis
Background: The GOLDENEYE study is an international, multicenter, prospective observational investigation designed to compare the outcomes of various management strategies for acute cholecystitis in patients aged 70 years and…
- Trial name
- GOLDENEYE (NCT07006298)
- Where
- Spain
- Volunteers
- 376 people
- Sponsor
- Instituto de Investigación Sanitaria y Biomédica de Alicante
Chronic Pancreatitis, Pancreatic Cancer
A Prospective Study of EUS Guided Celiac Block
The purpose of this prospective study is to measure the clinical effectiveness of EUS-guided CB in subjects, 50 who have chronic pancreatitis and 50 who have pancreatic cancer, that are already undergoing celiac block for…
- Trial name
- NCT00583271
- Testing
- triamcinolone, 98% dehydrated alcohol
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Indiana University
Gallbladder Polyps or Masses Greater Than 8-10 mm in Size
Diagnostic Value of Endoscopic Ultrasound Elastography and Contrast Enhanced Endoscopic Ultrasound for Differential Diagnosis of Gallbladder Polyp
Gallbladder polyps are often detected incidentally by ultrasonography. The most of gallbladder polyps are non-neoplastic such as cholesterol polyps and do not need further treatments.
- Trial name
- NCT04416763
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Musculoskeletal Disorders (MSDs), Occupational Diseases
Active Pauses for Musculoskeletal Disorder Prevention in Workers
The goal of this clinical trial is to learn if short exercise breaks at work can prevent muscle and joint pain in workers. The main questions it aims to answer are: Do strength exercises help workers move better and feel less…
- Conditions
- Musculoskeletal Disorders (MSDs), Occupational Diseases, Sedentary Behaviors, Prevention
- Trial name
- NCT07417527
- Testing
- Strength Active Pause, Mobility Active Pause
- Where
- Spain
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Malignant Ascites
EUS-Guided Drainage of Refractory Malignant Ascites
This study evaluates the efficacy and safety of drainage of refractory malignant ascites by endoscopic ultrasound-guided (EUS-Guided) implantation of plastic prostheses.
- Trial name
- NCT03550560
- Testing
- EUS-Guided drainage
- Volunteers
- 100 people
- Sponsor
- Hospital Universitario Virgen Macarena
Chronic Pancreatitis, Acute Recurrent Pancreatitis
Incorporating Endoscopic Ultrasound and Elastography Towards Improving Outcomes of Pediatric Pancreatitis Management
The main reason for this research study is to find out more about acute recurrent pancreatitis and chronic pancreatitis in children.
- Trial name
- NCT06068426
- Testing
- Transabdominal ultrasound Shear wave elastography
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- David Vitale MD
Pancreatic Pseudocyst
A Study to Evaluate the Effectiveness and Safety of EUS-guided Transluminal Drainage With 'Niti-S SPAXUS Stent'
The purpose of this study is to evaluate the safety and effectiveness of endoscopic ultrasound (EUS)-guided transluminal drainage with 'Niti-S SPAXUS Stent' for the treatment of pancreatic pseudocyst.
- Trial name
- NCT02730663
- Testing
- Niti-S SPAXUS Stent
- Where
- 6 sites in South Korea
- Volunteers
- 36 people
- Sponsor
- Taewoong Medical Co., Ltd.
Periampullary Neoplasms
Endoscopic Ultrasound Staging of Periampullary Neoplasms: Retrospective
The purpose of this retrospective study is to determine the degree to which a biliary stent affects EUS staging accuracy of ampullary tumors.
- Trial name
- NCT00880633
- Where
- United States
- Sponsor
- Indiana University
Pancreatic Cancer, Endoscopic Ultrasound
Ex-vivo Ultrasound Guided Radiofrequency Ablation on Pancreatic Solid Lesions
The study investigates the feasibility and the efficacy to treat pancreatic solid lesions as pancreatic adenocarcinomas (PDAC) and neuroendocrine tumors (NET) with ex-vivo radiofrequency ablation (RFA) under ultrasound (US)…
- Conditions
- Pancreatic Cancer, Endoscopic Ultrasound, Radiofrequency Ablation
- Trial name
- NCT06371716
- Testing
- ex-vivo RFA under US control at 10 Watts (W) of power in 3 differents arms of lesions, ex-vivo RFA under US control at 30 Watts (W) of power in 3 differents arms of lesions, ex-vivo RFA under US control at 50 Watts (W) of power in 3 differents arms of lesions
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- IRCCS San Raffaele
Liver Fibroses
EUS Elastography for Predicting Cirrhotic-related Complications
Evaluation of the tissue stiffness as a surrogate marker of degree of liver cirrhosis has gained popularity in recent decades. Current guidelines also advocate the use of Fibroscan® machine (EchoSens, Paris, France) to detect any…
- Trial name
- NCT04155398
- Testing
- EUS elastography
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Liver Steatosis, Fibrosis, Liver
Endoscopic Ultrasound Shear Wave for Liver Fibrosis in MASLD Patients: The RUMIPAMBA Trial
Currently, there is no description of the contribution of the endoscopic ultrasound (EUS)-guided shear wave elastography (SWE) when describing liver fibrosis in patients with screening criteria of metabolic dysfunction-associated…
- Trial name
- NCT06102980
- Testing
- Transparietal ultrasound (US)-based shear wave elastography (SWE) attenuation measurement, Transparietal ultrasound (US)-based shear wave elastography (SWE) stiffness measurement, Vibration-controlled transient elastography (VCTE) attenuation measurement
- Where
- Ecuador
- Volunteers
- 30 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas