Clinical trials: EUS
Neoplasms, Cystic, Mucinous, and Serous, Pancreatic Neoplasms
Endoscopic Ethanol Ablation of Communicating Pancreatic Cystic Neoplasms
Pancreatic cysts are common, and some pancreas cysts have malignant potential. Usual treatment of these cysts is either observation or surgical removal of part or all of the pancreas.
- Conditions
- Neoplasms, Cystic, Mucinous, and Serous, Pancreatic Neoplasms, Ultrasonography, Interventional
- Trial name
- NCT01057355
- Testing
- EUS and/or ERCP with ethanol injections of pancreatic cyst
- Sponsor
- Mayo Clinic
Sedation
Sedation of Advanced Endoscopic Procedure
To evaluate the impacts of target-control infusion (TCI) and bispectral index (BIS) monitoring during advanced endoscopic procedure.
- Trial name
- NCT03172078
- Testing
- advanced endoscopic procedure
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Acute Cholecystitis
Cholecystitis Outcomes in the Investigation of Cholecystectomy Versus EUS-GBD
Acute cholecystitis is common in elderly patients and becomes more frequent with increasing age. Standard treatment is laparoscopic cholecystectomy (LCC), but operative treatment may be associated with increased risk in older…
- Trial name
- CHOICE (NCT07678541)
- Testing
- LCC, EUS-GBD
- Where
- Finland
- Volunteers
- 116 people
- Sponsor
- Oulu University Hospital
Malignant Hepatobiliary Neoplasm
Endoscopic Ultrasonography Guided Biliary Drainage
Endoscopic ultrasonography is a widely accepted modality for the diagnosis of gastrointestinal and pancreatic-biliary diseases. Endoscopic ultrasonography-guided biliary drainage has attracted attention as an alternative…
- Trial name
- NCT03195075
- Testing
- Endoscopic ultrasonography guided biliary drainage, Percutaneous trans-hepatic biliary drainage
- Volunteers
- 40 people
- Sponsor
- Assiut University
Gastric Tumor, Early Gastric Cancer
Endoscopic Ultrasonographic Staging and Conventional Endoscopic Staging for Depth of Invasion for Early Gastric Cancer
The accurate prediction of depth of tumor invasion in early gastric cancer is essential for the proper selection of candidates for endoscopic resection.
- Trial name
- NCT01832246
- Where
- South Korea
- Volunteers
- 560 people
- Sponsor
- Seoul National University Hospital
EUS Guided Cyanoacrylate Injection, Endoscopic Variceal Band Ligation
EUS Glue vs Endoscopic Variceal Band Ligation for Prevention of Rebleeding in Patients With HCC and EV Bleeding: a Retrospective Comparative Study
SP by EUS-CYA improves clinical outcomes (eg, EV rebleeding) in patients with HCC and prior EV bleeding when compared with SP by EGD-VBL
- Conditions
- EUS Guided Cyanoacrylate Injection, Endoscopic Variceal Band Ligation, Hepatocelular Carcinoma, Esophageal Variceal Bleeding
- Trial name
- EUSgluevsVBL (NCT04918459)
- Where
- Hong Kong
- Volunteers
- 70 people
- Sponsor
- Chinese University of Hong Kong
Portal Hypertension
Utility of EUS-elastography to Predict Portal Hypertension
Patients with cirrhosis have structural and functional alterations of the liver. The progressive deposition of hepatic fibrosis is related to the subsequent development of portal hypertension (PH), and PH is associated with mayor…
- Trial name
- NCT03155282
- Testing
- EUS-E to measure liver and spleen stiffness.
- Where
- Ecuador
- Volunteers
- 61 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Portal Hypertension, Liver Cirrhosis
Efficacy and Safety of EUS-Guided Therapy Versus BRTO for Gastric Varices With Shunt
This study is a retrospective, multi-center and observational clinical study. Renmin Hospital of Wuhan University, Beijing Friendship Hospital, Capital Medical University, The fifth medical center of PLA General Hospital…
- Conditions
- Portal Hypertension, Liver Cirrhosis, Gastric Varix, Portosystemic Shunt
- Trial name
- NCT04828369
- Testing
- EUS-guided coil embolization combined with endoscopic cyanoacrylate injection, balloon-occluded retrograde transvenous obliteration
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Renmin Hospital of Wuhan University
Lung Cancer
EUS-B-FNA in the Diagnosis of Malignant Parenchymal Lung Lesions
The aim of this study is to evaluate the diagnostic accuracy, safety and tolerability, predictors of success of EUS-B-FNA in the diagnosis of malignant parenchymal lung lesions.
- Trial name
- NCT03983005
- Testing
- EUS-B-FNA
- Where
- 4 sites in Italy
- Volunteers
- 107 people
- Sponsor
- University of Milan
Lung Cancer
EUS-FNA in the Pre-Operative Evaluation of Patients With Lung Cancer
This trial examines the role of EUS-FNA (Oesophageal Endoscopic Ultrasound with Fine Needle Aspiration) as an endoscopic technique for the mediastinal staging of patients with lung cancer.
- Trial name
- NCT00119470
- Testing
- EUS-FNA, Conventional Surgical Technique
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Hospital, Ghent
Gastrointestinal Stromal Tumor of Stomach, Submucosal Tumor of Stomach
MCB vs EUS-FNA for Preoperative Pathological Evaluation of Gastric SMT
Gastrointestinal stromal tumors (GISTs) are the most common submucosal tumors (SMTs) of the stomach. The 2022 European Society of Oncology ESMO Diagnosis and Treatment Guidelines recommend that GISTs undergo biopsy with a clear…
- Trial name
- NCT06748690
- Testing
- mucosal cutting biopsy, endoscopic ultrasound-guided-fine needle aspiration
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Peking University People's Hospital
Primary Aldosteronism, Aldosterone-Producing Adenoma
Endoscopic Ultrasound-guided Radiofrequency Ablation in Primary Aldosteronism
In this study, the investigators will perform endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) treatment of left-sided adrenal tumours in patients with primary aldosteronism (PA) and in patients with mild autonomous…
- Conditions
- Primary Aldosteronism, Aldosterone-Producing Adenoma, Hypercortisolism
- Trial name
- NCT05368090
- Testing
- EUS-RFA of left adrenal tumour in PA with AVS-verified left lateralisation, EUS-RFA of left adrenal tumour in PA, "debulking group", EUS-RFA of left adrenal tumour in MACS with AVS-verified left lateralisation
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Haukeland University Hospital
Gastrointestinal Stromal Tumor (GIST)
Endoscopic Ultrasound Radiofrequency Ablation for GISTs
Nowadays, for the selection of the treatment for gastrointestinal stromal tumors (GISTs), tumor size, prognosis, resectability and stage should be considered.
- Trial name
- NCT05453292
- Testing
- Endoscopic ultrasound guided radiofrequency ablation
- Where
- Ecuador
- Volunteers
- 30 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Pancreatic Cancer
Pharmacotyping of Pancreatic Patient-derived Organoids
EUS-FNB samples will be used for organoid cultures, which will be co-cultured with cancer associated fibroblasts derived from the surrounding stroma of the lesion.
- Trial name
- NCT05196334
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 88 people
- Sponsor
- Herlev Hospital
Pancreatic Cancer
Contrast Enhanced EUS in the Evaluation of Pancreatic Cancer and Pancreatic Masses
Contrast enhanced EUS with the sonographic contrast agent DEFINITY™ has the potential to detect pancreatic cancer at an earlier stage, to improve current method of T staging and assessment of surgical resectability and also to…
- Trial name
- NCT01703026
- Where
- Singapore
- Volunteers
- 33 people
- Sponsor
- Changi General Hospital
Pancreatic Diseases
Red Cell Lysis Buffer Application Versus Conventional Sample Processing in EUS-FNB
The goal of this clinical trial is to evaluate the application of red cell lysis buffer (RCLB) versus conventional sample processing in endoscopic ultrasonography (EUS)-guided biopsy for solid pancreatic lesions.
- Trial name
- NCT05954221
- Testing
- Red cell lysis buffer (RCLB) application, Conventional processing
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Changhai Hospital
Non Small Cell Lung Cancer (NSCLC), Indication Mediastinal Staging
Single Scope Staging of Lung Cancer With Endosonography
Rationale: Lung cancer is the most commonly diagnosed cancer worldwide and is the most frequent cause of cancer death. Accurate staging is important because it directs treatment and prognosis.
- Conditions
- Non Small Cell Lung Cancer (NSCLC), Indication Mediastinal Staging, Complete Endosonography
- Trial name
- SCORE (NCT02014324)
- Testing
- Endosonography
- Where
- 9 sites in Belgium, Netherlands
- Volunteers
- 215 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Tumor
Follow-up of the Natural Course of the Small EUS-suspected Gastric Gastointestinal Stromal Tumors
Gastric gastrointestinal stromal tumors (GISTs) less than 2 cm are usually followed up conservatively. However, little is known about the natural course of small GISTs.
- Trial name
- NCT01084460
- Sponsor
- National Taiwan University Hospital
Pancreatic Cancer, Adult
Pancreatic Cancer Screening for At-risk Individuals
The investigators' goal is to conduct a prospective multicenter study to evaluate the yield and outcomes of screening of pancreas cancer in individuals who are at-risk for pancreatic cancer.
- Trial name
- PancreasScan (NCT05006131)
- Testing
- Screening for pancreatic cancer
- Where
- United States
- Volunteers
- 1,395 people
- Sponsor
- Beth Israel Deaconess Medical Center
Pancreatic Cyst, EUS-FNA
CHARM II: Chemotherapy for Ablation and Resolution of Mucinous Pancreatic Cysts
The purpose of this study is to evaluate the efficacy and safety of chemotherapeutic pancreatic cyst ablation using ethanol lavage followed by the infusion of a dual-agent chemotherapeutic cocktail (paclitaxel + gemcitabine)…
- Trial name
- CHARM (NCT03085004)
- Testing
- Ethanol, Normal saline, Paclitaxel + Gemcitabine admixture
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Milton S. Hershey Medical Center