Clinical trials: Eating Pathology
Appetite, Obesity and Obesity-related Medical Conditions
Metabolic Effects of Short-term Ultra-processed Food Intake (MEST-UPF)
The overall aim of this project is to study the effects of short-term high ultra-processed food intake, compared to nutrient- and energy density matched low ultra-processed food (UPF) intake, on energy intake and appetite.
- Trial name
- NCT07213245
- Testing
- Meal high in energy density, high in ultra-processed food, Meal high in energy density, low in ultra-processed food, Meal low in energy density, high in ultra-processed food
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Obesity, Depressive Symptoms
The MIND-GUT Digital Pilot Intervention Study
This 12-week pilot study aims to evaluate the feasibility and effectiveness of a dietary intervention targeting diet, obesity, mental health, and the gut microbiome in promoting weight loss and enhancing mental health among obese…
- Conditions
- Obesity, Depressive Symptoms, Anxiety, Stress
- Trial name
- MINDGUT (NCT06374407)
- Testing
- Dietary intervention based on the MIND diet
- Where
- Sweden
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Skövde
Dietary Change, Obesity & Overweight
Dietary Peanuts and Nutrition-Related Outcomes
This study will look at how eating peanuts every day might affect participants weight, how healthy their diet is, and how they feel when eating.
- Conditions
- Dietary Change, Obesity & Overweight, Food Acceptance
- Trial name
- NCT07244458
- Testing
- Peanuts, Dual-energy X-ray absorptiometry (DEXA) scans
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Ian J. Neeland, MD
Eating Disorder
Monoamine Contributions to Neurocircuitry in Eating Disorders
This study will use brain imaging technologies to measure several neurotransmitters (serotonin and dopamine) that contribute to our abilities to respond to reward or inhibit our impulses, and which are known to be altered in the…
- Trial name
- NCT02020408
- Testing
- [11C]raclopride, [11C]DASB, amphetamine
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Weight Loss, Diet, Healthy
Delicious Eating for Life in Southern Homes
This study will compare a new weight loss program that focuses on a healthy eating pattern, with WW™ (formally Weight Watchers), an effective and widely available weight loss program.
- Conditions
- Weight Loss, Diet, Healthy, Cardiovascular Risk Factor
- Trial name
- DELISH (NCT04302727)
- Testing
- Med-South Weight Loss Intervention, WW
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Mental Health Impairment, Mental Health
Mental Health in Dancers; an Intervention Study
International studies reveal high prevalence of eating disorders (ED) and mental health issues amongst professional dancers, and the Norwegian National Ballet's house previously (2005) reported a lifetime prevalence of ED by 50%…
- Conditions
- Mental Health Impairment, Mental Health, Eating Disorders, Perfectionism
- Trial name
- MeHeDa (NCT04085861)
- Testing
- Mental health literacy in dancers, Mental health literacy in dance teachers
- Where
- Norway
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Healthy, Overweight
Study to Evaluate the Effect of Gum Acacia (FibregumTM) on Post-prandial Glucose, Insulin Levels and Food Intake
Study to evaluate the effect of gum acacia (FibregumTM) on post-prandial glucose and insulin levels and food intake in normal-weight and overweight subjects during a 2-7 weeks intervention period.
- Trial name
- NCT04515277
- Testing
- 40 g Gum acacia (FibregumTM), 20 g Gum acacia (FibregumTM), 0 g Gum acacia (FibregumTM)
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Nexira
Obesity, Binge-Eating Disorder
fMRI Study of Emotion Regulation in Patients Suffering From Obesity With or Without Binge Eating Disorder and Seeking Bariatric Surgery
Obesity is a major public health problem and Binge eating disorder (BED) is very frequently observed in patients considered for weight loss surgery and seems to influence their outcome critically.
- Trial name
- OBéMO (NCT05131256)
- Testing
- Neurofunctional characterization of emotional regulation (fMRI)
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Anorexia Nervosa, Atypical Anorexia Nervosa
Optimizing Provider Training in Eating Disorders (OPTED)
This is a randomized controlled trial for mental health clinicians comparing two methods of training in family-based treatment (FBT) for restrictive eating disorders.
- Trial name
- OPTED (NCT05389657)
- Testing
- Web-based training, Live training
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Eating Disorders
Swedish Body Project for Prevention of Eating Disorders
Women in general and young girls in particular are constantly exposed to unhealthy body and appearance ideals through media that contribute to body dissatisfaction and unhealthy behaviors such as rigid dieting, which in…
- Trial name
- sBodyProject (NCT02567890)
- Testing
- Internet-based DBI, Expressive writing
- Where
- Sweden
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Eating Disorders, Obesity
Combined Eating Disorder and Weight Loss Online Guided-Self Help Intervention
Online, guided self-help interventions have been used for weight-loss (WL), as well as for treatment of eating disorders (EDs), separately, but no program exists to manage these conditions together.
- Trial name
- NCT04248686
- Testing
- CoED Online Intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Mental Health Issue, Physical Health
Mental Health and Symptoms of Energy Deficiency (REDs) in Young Biathletes
Participation in weight-sensitive sports has been identified as a significant risk factor for low energy availability (LEA), relative energy deficiency in sport (REDs), and eating disorders.
- Trial name
- NCT06487260
- Where
- 2 sites in Norway
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ostfold University College
Obesity
Sleep Deprivation and Energy Balance
Observational and epidemiological studies have found a link between obesity and short sleep duration with the prevalence of both increasing in the past decades.
- Trial name
- Sleep (NCT00935402)
- Testing
- Sleep
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Obesity
Child Health Initiative for Lifelong Eating and Exercise (CHILE)
Child Health Initiative for Lifelong Eating and Exercise (CHILE) is a trans-community multidisciplinary site-specific intervention and evaluation plan for a Head Start and family-based culturally and developmentally appropriate…
- Trial name
- CHILE (NCT00428805)
- Testing
- classroom curriculum, In-service training for Head Start teachers/aides, Training for Head Start food service
- Where
- United States
- Volunteers
- 980 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Eating Disorders
Effectiveness of a Dissonance-Based Eating Disorder Prevention Program (The Body Project II)
This study will evaluate the effectiveness of dissonance-based eating disorder prevention programs in reducing body dissatisfaction among young women with body image concerns.
- Trial name
- NCT00663754
- Testing
- Dissonance-based eating disorder prevention program, Educational brochure
- Where
- United States
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Obesity, Healthy Diet
Pricing Interventions Based on Energy Content in Restaurants
The goal of this clinical trial is to examine the impact of price decreases based on energy content in a full-service restaurant on immediate dietary consumption (in terms of kilocalories (kcals), sugar, fat, and salt intake) and…
- Conditions
- Obesity, Healthy Diet, Eating Behavior
- Trial name
- NCT05818345
- Testing
- Pricing intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Obesity, Endocrine; Obesity
The Effect of Food Supplements on Food Intake and Gut Hormone Levels
When a meal is eaten, nutrients activate the release of hormones from the bowel into the blood stream. Normally there is a large amount of hormone released, which tells the brain that an individual is full and to stop eating.
- Conditions
- Obesity, Endocrine; Obesity, Appetite; Perverted
- Trial name
- NCT04292236
- Testing
- Lauric Acid, Perilla Oil and Diindolylmethane
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Bulimia Nervosa, Eating Disorders
Effectiveness of Antibiotic Treatment for Reducing Binge Eating and Improving Digestive Function in Bulimia Nervosa
This study will determine the effectiveness of the antibiotic erythromycin in enhancing gastrointestinal function and decreasing the frequency of binge eating in people with bulimia nervosa.
- Trial name
- NCT00304187
- Testing
- Erythromycin
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Obesity
Effect of Quinine Hydrochloride in Overweight Population on Food Intake, Hunger and Gut Peptide Release
The worldwide increase in the prevalence of obesity is a cause of great concern. Pharmacological treatment options are being explored at the moment with a major focus on the hormones produced by the gastrointestinal tract which…
- Trial name
- NCT04873011
- Testing
- Quinine Hydrochloride
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obesity
Think AHEAD (A Healthy Eating And Drinking) Study
Advice to increase water consumption as part of a weight-reducing diet - typically to 8 cups (64 fl oz, ~2 L) per day ("8x8" water recommendation) - is almost ubiquitously recommended by healthcare professionals.
- Trial name
- NCT01044134
- Testing
- Dietary counseling
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital