Clinical trials: Echocardiography, Doppler
Critical Illness, Elevated Left Atrial Pressure
The Use of Single-Beat TE-e' in Evaluation of Left Atrial Pressure in Critically Ill Patients: The TELAP-ICU Trial
This study evaluates a new single-beat echocardiographic technique (TE-e', the time difference between the onset of the mitral inflow E wave and the septal e' wave on tissue Doppler imaging) for estimating left atrial pressure…
- Conditions
- Critical Illness, Elevated Left Atrial Pressure, Left Ventricular Diastolic Dysfunction, Echocardiography
- Trial name
- TELAP-ICU (NCT07820319)
- Testing
- Echocardiography
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Mechanical Circulatory Support
BRAIN-HEART Ultrasound Study Normative Values for Transcranial Doppler Based Cerebral Blood Flow Assessment
There is a dire need to establish normative values for transcranial Doppler(TCD) derived cerebral blood flow parameters for each type of Mechanical circulatory support (MCS) device and explore the relationship between the MCS…
- Trial name
- MCS (NCT05924503)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Wake Forest University Health Sciences
Acute Coronary Syndrome, Myocardial Infarction (MI)
Clinical Echocardiography and S' Wave for Early Recognition of Acute Coronary Syndrome in the Emergency Department, A Prospective Study
The goal of this prospective observational study is to assess the diagnostic accuracy of the tissue Doppler imaging (TDI) S' wave in detecting acute coronary syndrome (ACS) in adult patients presenting to the emergency department…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction (MI), Non-ST Elevation Myocardial Infarction, Unstable Angina
- Trial name
- CLEAR_ECHO (NCT06860997)
- Testing
- Tissue Doppler Imaging (TDI) S' Wave Echocardiography
- Where
- Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Diabetes type1, Healthy
Impact of Gravity on Cardiac Hemodynamics
The goal of this clinical trial is to define and compare pre-load dependance of the cardiac function according to the intracardiac hydrostatic gradient of pressure in healthy and diabetic populations.
- Trial name
- ACUITY (NCT06190756)
- Testing
- Cardiovascular and Baroreflex stimulation by Tilting, Cardiovascular and Baroreflex stimulation by Lower Body Negative Pressure
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Doppler Echocardiography, Postpartum Septic Shock
Doppler Echocardiography Versus Clinical Targets Guided Therapy on the Outcome of Postpartum Septic Shock.
Postpartum sepsis is widely known as a preventable main cause of maternal morbidity and mortality. According to the World Health Organization, approximately 11% of the estimated maternal deaths worldwide were attributed to…
- Trial name
- NCT06757985
- Testing
- a clinically guided resuscitation protocol,, a transthoracic bedside focused echocardiographic assessment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Smoking
Acute Cardiovascular Effects of Cigarette Smoking
Twenty healthy smokers will be subjected to measurement of Pulse, Blood Pressure, electrocardiogram (ECG) and Echo at baseline and after smoking a cigarette.
- Trial name
- NCT01346956
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Andhra Medical College
Haemodynamic Rebound
Hemodynamic Repercussions of Noninvasive Ventilation
The noninvasive ventilation (NIV) is a method of ventilatory support that does not require artificial airway. Its application is associated with complex hemodynamic repercussions, therefore is important to identify them for…
- Trial name
- NCT02139631
- Testing
- Noninvasive ventilation
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Congenital Heart Defects
Assessing the Hemodynamic Benefits of Cardiac Resynchronization Therapy in Children Following Open-Heart Surgery
Malformations of the heart (congenital heart disease) are the most common congenital birth defects, occurring in about 1% of children.
- Trial name
- NCT00397514
- Testing
- Congenital Heart Surgery Patients
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- University of British Columbia
Sickle Cell Disease
Evaluation of the Prevalence of Pulmonary Hypertension in Adult Patients With Sickle Cell Disease
Recent data show that pulmonary hypertension (PH), defined by a tricuspid regurgitation jet (TRJ) velocity > or equal at 2.5m/s on Doppler echocardiography, is present in about 30% of adults with sickle cell disease (SCD) and is…
- Trial name
- ETENDARD (NCT00434902)
- Where
- France
- Volunteers
- 700 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mitral Valve Insufficiency
Determinants of the Progression and Outcome of Mitral Regurgitation
Mitral regurgitation (MR) is one of the most frequent valve lesions, both in North America and in Europe, and its prevalence is increasing with the aging of the population.
- Trial name
- PROGRAM (NCT01835054)
- Testing
- Blood biomarkers, DNA collection, Echocardiography
- Where
- 4 sites in Belgium, Canada and 1 more
- Volunteers
- 440 people
- Sponsor
- Laval University
Heart Failure
Utility of Tissue Doppler Echocardiography for Selecting Patients for Cardiac Resynchronisation Therapy
Currently the main selection tool for Cardiac Resynchronisation Therapy (CRT) is the QRS duration on the surface echocardiography (ECG) which has been shown to be a poor predictor of response.
- Trial name
- TIBI-HF (NCT01100918)
- Testing
- BiV ICD, ICD
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Barts & The London NHS Trust
Arthritis, Rheumatoid, Spondylitis, Ankylosing
Heart Function in Rheumatoid Arthritis and Ankylosing Spondylitis Pre and Post-TNF Blocker
The purpose of this study is to determine possible alterations in cardiac function in patients with Rheumatoid Arthritis and Ankylosing Spondylitis under anti-TNF therapy, without clinical heart disfunction at baseline, using…
- Trial name
- NCT01072058
- Testing
- TNF blockers (infliximab, adalimumab, etanercept)
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo
Surgery--Complications, Congestive Heart Failure
The Clinical Significance of Portal Hypertension After Cardiac Surgery: a Multicenter Prospective Observational Study
Portal flow pulsatility detected by Doppler ultrasound is an echographic marker of cardiogenic portal hypertension from right ventricular failure and is associated with adverse outcomes based on previous studies performed at the…
- Conditions
- Surgery--Complications, Congestive Heart Failure, Right Heart Failure, Anesthesia
- Trial name
- TECHNO-MULTI (NCT03656263)
- Testing
- Doppler assessment of portal vein flow
- Where
- Canada
- Volunteers
- 360 people
- Sponsor
- Montreal Heart Institute
Diastolic Dysfunction
Effect of Exercise on Heart Function in Healthy Elderly People
The purpose of this study is to determine the effect of aerobic interval training on left- and right ventricular diastolic- and systolic function on healthy, sedate people over 70 years.
- Trial name
- NCT00804518
- Testing
- Aerobic interval training
- Where
- Norway
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Heart Failure With Preserved Ejection Fraction, Diastolic Heart Failure
Classification of Heart Failure With Preserved Ejection Fraction
The purpose of this study is to create a classification system for the heterogenous disorder of heart failure with preserved ejection fraction (HFpEF).
- Trial name
- NCT01030991
- Where
- United States
- Volunteers
- 514 people
- Sponsor
- Northwestern University
Stenosis, Aortic
Omics in Valvular Disease
The aim of our study is to investigate the effects of impaired left ventricular remodeling on the short- and long-term prognosis in AS partecipants undergoing extracorporeal circulation during valve repair surgery and in…
- Trial name
- OVERLOAD (NCT05768594)
- Testing
- Blood sample
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Aortic Valve Stenosis, Aortic Valve Regurgitation
Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR
Data on valve performance following ViV-TAVR has usually been obtained with the use of Doppler-echocardiography. However, some reports have shown significant discordances in the evaluation of mean transvalvular gradient between…
- Conditions
- Aortic Valve Stenosis, Aortic Valve Regurgitation, Prosthesis Failure
- Trial name
- ECHOCATH (NCT05459233)
- Testing
- Doppler-echocardiography, Invasive hemodynamic measurements
- Where
- 7 sites in United States, Canada
- Volunteers
- 310 people
- Sponsor
- Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Valvular Heart Disease, Ischemic Heart Disease
Effect of Isoflurane on Tissue Doppler Imaging of Mitral Annulus During Cardiac Surgery
The purpose of this study is to determine Isoflurane's dose-dependent effect on left ventricular (LV) systolic function in cardiac surgery.
- Trial name
- NCT01819012
- Testing
- Isoflurane 1.0 MAC, Isoflurane 1.5 MAC, Isoflurane 2.0 MAC
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Konkuk University Medical Center
Cardiac Output Measurement
MostCare Versus Echo-Doppler for Cardiac Output Measurement
Recently, an uncalibrated minimally invasive Pulse-code Modulator (PCM) has been developed: the MostCare system. This monitoring system is powered by Pressure Recording Analytical Method (PRAM), which is based on the mathematical…
- Trial name
- PRAM (NCT01678950)
- Where
- 14 sites in France, Italy and 2 more
- Volunteers
- 400 people
- Sponsor
- Azienda Ospedaliera Universitaria Senese
Echocardiography
Cardiac Output Assessment by Using Saline Contrast Injection
Cardiac output (CO) assessment is one of the cornerstone of hemodynamic evaluation in ICU patients. CO is usually measured using invasive methods or non-invasive methods.
- Trial name
- CardioLog (NCT04310904)
- Testing
- contrast assessment of cardiac output (CO), cardiac Doppler technique
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire, Amiens