Clinical trials: Edentulism, active
Edentulous Alveolar Ridge In Mandible, Complete Edentulism
Compare the Difference in Occlusal Force Distribution and Denture Retention Using 2 Different Denture Base Materials in Implant Retained Overdenture
The global increase in the aging population has led to a rise in total edentulism, which remains a major public health concern. two-implant-retained mandibular overdentures have been regarded as the standard of care, offering…
- Conditions
- Edentulous Alveolar Ridge In Mandible, Complete Edentulism, Dental Implant, Attachments
- Trial name
- NCT07250503
- Testing
- Conventional acrylic resin denture, Flexible resin denture
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Edentulism Complete, Edentulism
PRINTOW: Occlusal Wear of Denture Teeth in Digitally Fabricated Complete Dentures
This randomized controlled trial evaluates the occlusal wear of denture teeth fabricated using three digital workflows: 3D-printed denture teeth, CAD/CAM-milled double cross-linked denture teeth, and prefabricated denture teeth.
- Trial name
- Printow (NCT07585162)
- Testing
- CAD/CAM-Milled Denture Base with Milled Denture Teeth, CAD/CAM-Milled Denture Base with Prefabricated Denture Teeth, 3D-printed denture base and teeth
- Volunteers
- 45 people
- Sponsor
- Najla Chebib
Partial Edentulism Class 1 or Class 2
Comparative Evaluation of Artificial Intelligence-Assisted Versus Conventional Guided Implant Planning in Free End Saddle Cases
This study aims to compare the accuracy and clinical performance of artificial intelligence (AI)-assisted implant planning with conventional human-based implant planning in patients presenting with free-end saddle edentulous…
- Trial name
- NCT07891442
- Testing
- Dental implant palcement
- Volunteers
- 20 people
- Sponsor
- Mariam Morcos Nasr
Partial Edentulism Class 3
Immediate Loading in Single Tooth Implants
The planned study is designed to provide evidence for the application of early implant placement with partial bone-healing and either an immediate or an early restoration/ loading protocol.
- Trial name
- NCT05409287
- Testing
- Immediate Implant Loading, Early Implant Loading
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Bern
Peri-implant Soft Tissue Deficiency, Partial Edentulism
Soft Tissue Augmentation Around Dental Implants Using Connective Tissue Graft, Submerged Tenting Abutment, or Sub-crestal Implant Placement
Peri-implant soft tissue thickness is an important determinant of the long-term stability and success of dental implants. Patients with a thin peri-implant soft tissue phenotype are at increased risk of soft tissue recession…
- Conditions
- Peri-implant Soft Tissue Deficiency, Partial Edentulism, Tooth Loss
- Trial name
- NCT07714265
- Testing
- subepithelial connective tissue graft, Submerged Tenting Abutment, Sub-crestal Implant Placement
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Misr International University
Edentulism, Tooth Loss
5-Years PMCF Study of Ceramic Dental Implants One-piece Versus Two-piece.
The goal of this cohort observational study is to compare in the survival rate of ceramic dental implants placed in patients with missing or hopeless teeth .
- Trial name
- 240101 (NCT06287346)
- Testing
- dental implant
- Where
- 2 sites in United States, Spain
- Volunteers
- 652 people
- Sponsor
- CeraRoot SL
Complete Edentulism, Satisfaction, Patient
"Acrylic Vs. Metal Palatal Coverage in Complete Dentures: Patient-Reported Outcomes"
Conventional dentures can be uncomfortable and limit oral functionality due to the polished surfaces covering the palate and rugae areas.
- Conditions
- Complete Edentulism, Satisfaction, Patient, Quality of Life
- Trial name
- NCT06881199
- Testing
- Complete denture with a metallic Co-Cr casted palate, Complete denture with an acrylic palate
- Where
- Jordan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Biomechanical Phenomena, Partial Edentulism
Intraoral vs Extraoral Cementation of Zirconia Bridges on Ti-Bases: Microstrain Evaluation
This prospective clinical study compares two cementation techniques for implant-supported zirconia fixed partial dentures on titanium bases (Ti-bases): extraoral cementation performed on the working model and intraoral…
- Trial name
- NCT07448701
- Testing
- Extraoral cementation on Ti-bases, Intraoral cementation on Ti-bases
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universitat Internacional de Catalunya
Edentulism, Biological Aging
Biological Aging Following Full-Arch Implant-Supported Fixed Rehabilitation in Edentulous Patients
This study aims to investigate the association between full-arch implant-supported fixed dental rehabilitation and changes in biological aging among adults with complete tooth loss (edentulism).
- Trial name
- NCT07890753
- Testing
- Full-Arch Implant-Supported Fixed Dental Rehabilitation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Junyu Shi
Edentulous Alveolar Ridge, Complete Edentulism
Using Two Different Attachments in Mandibular Implant Overdenture Cases in Order to Retention and Patient Satisfaction
The Goal of the clinical trail is to evaluate the efficacy of Bar- OT Equator attachment on retention and patient satisfaction in comparison to the standard technique using Bar- clip attachment.
- Conditions
- Edentulous Alveolar Ridge, Complete Edentulism, Dental Implant, Attachments
- Trial name
- NCT06678945
- Testing
- Bar-Clip attachment, Bar- OT Equator attachment
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Edentulism, Edentulism Complete
Comparison of Non-Calibrated Splinting Bodies and T-Marker for Complete-Arch Implant Scanning
This randomized crossover clinical trial aims to compare the accuracy and scanning efficiency of two digital techniques for recording implant positions in completely edentulous patients receiving implant-supported full-arch…
- Trial name
- NCT07723404
- Testing
- Non-Calibrated Splinting Scan Body System (IoConnect), Mobile Phone-Based Photogrammetry System (T-Marker)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Alveolar Bone Loss, Edentulism Nos
The Application of a Biphasic Calcium Sulfate Graft Material in Sinus Floor Elevation
Pneumatization of the maxillary sinus may lead to insufficient bone volume for dental implant placement in the edentulous posterior maxilla.
- Trial name
- NCT06533397
- Testing
- Sinus floor elevation (SFE), preoperative cone beam computed tomography (CBCT), postoperative CBCT
- Where
- Hungary
- Volunteers
- 40 people
- Sponsor
- Semmelweis University
Atrophic Maxilla, Partial Edentulism
Prospective Study of Bone Augmentation With Lateral Sinus Lift and Osseointegration of Dental Implants
By using a split-mouth model in the maxilla, lateral sinus lift procedures will be performed using xenograft on one side vs autologous bone augmentation and PRF membranes on the other side.
- Trial name
- NCT07014085
- Testing
- "Histomorphometric Evaluation of Bone Augmentation Using Xenografts Versus Autologous Bone Grafts in Dental Implant Patients: A Comparative Clinical Study
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maria H. Pham
Edentulism in Lower Jaw, Edentulism
Evaluation of Different Attachments on Implant-Retained Mandibular Overdenture.
Patients will be selected from the outpatient clinic of Removable Prosthodontic Department. Faculty of Dental Medicine for Girls, Al-Azhar University..
- Trial name
- Overdenture (NCT06721377)
- Testing
- Novaloc attachment, Equator attachment
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Failure, Prosthesis, Dental Prosthesis, Implant-Supported
Clinical Performance of All-on-4 PEEK and Conventional Prostheses
The all-on-4 treatment approach for completely edentulous mandible is a proven concept. However, there are still issues regarding the use of metal substructure to support the prostheses such as allergy, metallic taste, and…
- Conditions
- Failure, Prosthesis, Dental Prosthesis, Implant-Supported, Survival, Prosthesis, Complete Edentulism
- Trial name
- NCT06388395
- Testing
- Accuracy of full-arch surgical guides, Survival and complications of the prostheses, Survival and complications of the implants
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Edentulism, Complete Maxillary Edentulism
Jaw Tracking Impact on Occlusion and Patient Outcomes in Maxillary Implant Restorations
This randomized clinical trial aims to evaluate the effect of integrating digital jaw tracking into the workflow for fabrication of full-arch maxillary implant-supported screw-retained restorations.
- Trial name
- NCT07693946
- Testing
- Conventional Prosthetic Workflow, Digital Jaw-Tracking Workflow
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Complete Edentulism
Microbial Adhesion and Peri-Implant Tissue Health in All-on-Four Hybrid Prostheses Supported by Zantex or Zirconia Frameworks
This study compares two materials (Zantex and Zirconia) used to make fixed full-arch dental prostheses supported by four dental implants (the "All-on-Four" technique) in patients who have no natural teeth in the lower jaw.
- Trial name
- NCT07811661
- Testing
- Zirconia Framework, Zantex Framework
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Kafrelsheikh University
Dental Implants, TNF-alpha Inhibitors
Dental Implant Healing With TNF-Alpha Inhibitors
The goal of this pilot study is to learn about healing after dental implant placement in patients taking a class of biologic drug called Tumor Necrosis Factor or TNF-alpha antagonist or inhibitor.
- Conditions
- Dental Implants, TNF-alpha Inhibitors, Edentulism
- Trial name
- NCT06538870
- Testing
- Placement of dental implants
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Edentulism, Complete Dentures
Accuracy of Digital vs Conventional Denture Impressions: An In Vivo Study
The goal of this clinical trial is to compare the accuracy of two denture impression techniques, digital intraoral scanning and conventional border-molded impressions, in adults who have lost all their teeth (fully edentulous…
- Conditions
- Edentulism, Complete Dentures, Digital Impression Accuracy, Dental Impression Techniques
- Trial name
- NCT07377890
- Testing
- Digital and conventional impressions
- Where
- United Arab Emirates
- Volunteers
- 10 people
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Edentulism, Implant-supported Full-arch Prosthesis
Accuracy of Intraoral Photogrammetry vs Optical Scanners for Immediate Full-Arch Implant Loading
This prospective in vivo clinical trial evaluates and compares the accuracy (trueness) and scanning time of intraoral photogrammetry scanners (IPS) versus conventional intraoral optical scanners (IOS) for immediate full-arch…
- Conditions
- Edentulism, Implant-supported Full-arch Prosthesis, Digital Impression Accuracy, Photogrammetry in Dentistry
- Trial name
- NCT07320729
- Testing
- Intraoral Optical Scanner, Intraoral Photogrammetry Scanner Elite (Shining3D)
- Where
- Egypt
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Abdelrahman Khalaf Eldabe