Clinical trials: Effect Increased
Gastroesophageal Disease
To Determine if Sleep Deprivation Results in Increased Esophageal Acid Exposure
The purpose of this study is to determine if sleep deprivation results in increased esophageal acid exposure in healthy controls and gastroesophageal reflux disease (GERD) patients.
- Trial name
- IRUSESOM0428 (NCT01093339)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Southern Arizona VA Health Care System
Atrial Fibrillation (AF)
Effects of a Health Belief Model-Based Community Educational Program to Increase the Awareness of Atrial Fibrillation Among Older Adults: a Randomized Controlled Trial
The goal of this study is to evaluate the effects of a theory-based community educational program among older adults in the community on atrial fibrillation (AF) knowledge.
- Trial name
- NCT06582823
- Testing
- Health belief model-based community educational program, Control
- Where
- Hong Kong
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Healthy, Placebo Response
Can Training Increase Reporting Accuracy and Study Power in Human Pain Trials
In previous studies, results of both the Focused Analgesia Selection Test (FAST) procedure, a method to assess pain-reporting accuracy, and the Evoked Pain Training (EPT) procedure, aimed to improve pain-reporting accuracy…
- Trial name
- NCT03952715
- Testing
- Ibuprofen 400 mg
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Muscle, Cognitive Functioning
This Study Investigates β-hydroxy-β-methylbutyrate (HMB) and 2-hydroxybenzylamine (2-HOBA), When Administered Either Individually or in Combination Contributes to an Increased Quality of Health, Specifically Improving Muscular Strength and Cognitive Functioning in Adults Over the Age of 65.
In this study, participants will be assigned to receive HMB, 2-HOBA, a combination of both, or a comparison supplement for a set period of time.
- Conditions
- Muscle, Cognitive Functioning, Geriatric, Ageing and Geriatric Health
- Trial name
- H2AGE (NCT07419633)
- Testing
- β-Hydroxy-β-methylbutyrate, 2-hydroxybenzylamine, β-Hydroxy-β-methylbutyrate and 2-hydroxybenzylamine
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Healthy
A Single Dose Study of Lu AG09222 in a Headache Model With Healthy Subjects
The purpose of this study is to evaluate how well Lu AG09222 can prevent blood vessel dilation in a headache model.
- Trial name
- NCT04976309
- Testing
- Lu AG09222
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Test if Increased Chewing Will Increased Microbiota SCFA Production
Particle Size Project
This study is designed to test the effects of chewing efficiency on human gut microbiome composition and function.
- Trial name
- EPSOM (NCT05091801)
- Testing
- Intervention
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Duke University
Osteoporosis
Effect of Soy Isoflavones on Bone Mineral Density and Physical Performance Indices
The aim of the present study was to investigate the effects of soy and soy plus isoflavones on bone mineral Density and physical performance in post menopausal women.
- Trial name
- SoyPTI (NCT00661856)
- Testing
- Soy protein
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Creighton University
Implant, Analgesia
Low Level Laser (LED) Use to Increase Dental Implant Stability and Post Operative Analgesia
Study hypothesis: Low level laser (LED) will reduce initial bone resorption and improve primary stability of dental implant. It will also reduces post operative pain compared to patient without treatment Implant osseointegration…
- Trial name
- NCT01097499
- Testing
- OsseoPulse device (Light emitting diode technology)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Stroke
Effects of Voluntary Adjustments During Walking in Participants Post-stroke
People post-stroke retain the capacity to modify walking patterns explicitly using biofeedback and implicitly when encountering changes in the walking environment.
- Trial name
- NCT06034119
- Testing
- Split belt treadmill, Biofeedback
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Chapman University
Obesity, Diet
Effect of Carbonated Soft Drinks on Appetite-Regulation
Compared to solid foods, the nutritional energy of drinks may bypass the appetite regulation leading to obesity development. Although drinks sweetened with aspartame are available the anticipated positive effect of these drinks…
- Trial name
- NCT00776971
- Testing
- Sugar-sweetened soft drink, Aspartame-sweetened soft drink, Semi-skimmed milk
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Obesity & Overweight
Supplementation With Sirtuin Activators in Women With Increased Body Weight
The goal of this clinical trial is to learn if the six-month supplementation with sirtuin activators can affect metabolism in 40-to-65-year old women with increased body weight.
- Trial name
- NCT07245979
- Testing
- Sirtuin activators
- Where
- Poland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Sedentary Lifestyle, Blood Pressure
Blueberry Enhances Activity and Cognition Through Increased Vascular Efficiency
Recent evidence suggests that increased berry intake results in a variety of health benefits, across multiple health domains. This 3-month randomized, double-blind, placebo-controlled trial assess the effects of combining daily…
- Conditions
- Sedentary Lifestyle, Blood Pressure, Arterial Stiffness, Overweight and Obesity
- Trial name
- BEACTIVE (NCT04049162)
- Testing
- Blueberry Plus Exercise (BB-EX)
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Duke University
Augmented Reality
AR vs In Person Simulation for Medical Workplace Training
This study will evaluate the physiologic and emotional effects of an augmented reality (AR) simulation versus an in-person simulation. This is a single institution, non-inferiority, randomized controlled trial.
- Trial name
- NCT05674188
- Testing
- Augmented Reality Headset
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Stanford University
Overweight and Obesity
Effect of Low-Volume HIT vs. MIC Exercise in Individuals With Increased BMI
To compare the effect of low volume high intensity training and moderate intensity continuous exercise on Rate Pressure Product (RPP) and functional capacity.
- Trial name
- NCT06584708
- Testing
- Low-volume high intensity interval training, Moderate intensity continuous exercise
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Time-restricted Feeding, Postprandial Lipemia
The Effect of Different Methods for Modulating Postprandial Fat Oxidation on Postprandial Lipemia the Next Day
Background: Studies have revealed that time-restricted feeding affects the fat oxidation rate; however, its effects on the fat oxidation rate and hyperlipidemia following high-fat meals are unclear.
- Trial name
- NCT05251103
- Testing
- time-restricted feeding trial
- Where
- Taiwan
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Insulin Resistance, Type 2 Diabetes
Dietary Protein and Insulin Sensitivity Study
The overall objective of the Dietary Protein and Insulin Sensitivity Study is to test the hypothesis that increased protein in a diet with reduced carbohydrate (35% energy) can ameliorate insulin resistance in the absence of…
- Conditions
- Insulin Resistance, Type 2 Diabetes, Metabolic Syndrome, Cardiovascular Disease
- Trial name
- NCT00508937
- Testing
- Diet
- Where
- 2 sites in United States
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Peri-Implantitis
SPiT-frequency; the Effect of Increased Frequency of Intervention on Post-surgical Peri-implant Inflammation
This pilot study is an interventional clinical study on the supportive peri-implant treatment (SPiT) necessary to maintain/ improve the clinical conditions surrounding a dental implant following surgical treatment of…
- Trial name
- SPiT-freqvzy (NCT04705012)
- Testing
- Submucosal supportive therapy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Chronic Heart Failure
Effect of Enhanced Sweat Rate on the Safety and Edema Status of Chronic Edematous Patients
The purpose of this study is to demonstrate safety and performance of AquaPass System for enhancing fluid transfer through the skin, by increased sweat rate, in edematous patients.
- Trial name
- NCT04578353
- Testing
- The AquaPass System
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- AquaPass Medical Ltd.
Randomised Controlled Trial, Public Health Nursing
Program to Increase Fathers' Involvement in Infant Care
Fathers participating in the study will be given an 8-week formality intervention. Participants will be shown 4-week infant care training records and then 4-week videos prepared on educational topics.
- Conditions
- Randomised Controlled Trial, Public Health Nursing, Child Health
- Trial name
- Infant Care (NCT06969248)
- Testing
- Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Periodontal Intrabony Defects
Effects of Modified Minimally Invasive Surgical Technique With Clindamycin Augmented Platelet-rich Fibrin Versus Platelet-rich Fibrin Alone for Management of Periodontal Intrabony Defects.
Periodontal infections in the oral cavity are strongly associated with clinical outcomes of both regenerative and conventional surgical procedures and should receive proper attention.
- Trial name
- NCT05177198
- Testing
- M-MIST + Clindamycin augmented PRF, M-MIST + PRF
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University