Clinical trials: Effect Increased
Stroke, Hemiparesis
Effects of Different Types of Augmented Feedback on Intrinsic Motivation and Spatiotemporal Gait Performance After Stroke
Investigate development of an Innovative Instrument on Robot-Aided and Virtual Reality Rehabilitation for Intelligent Physical Training (i.e. gait and stepping) of Individuals post-stroke.
- Conditions
- Stroke, Hemiparesis, Walking, Difficulty
- Trial name
- NCT04740060
- Testing
- Augmented Feedback without Virtual Reality(VR, Augmented Feedback with Non-Game based VR, Augmented Feedback with Game based VR
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- University of Alabama at Birmingham
Drug Effect
The Effects of Sacubitril/Valsartan on the Heart Functions
Background: Sacubitril/valsartan, has been found to be more beneficial than enalapril for reducing the incidences of sudden cardiac death, death from worsening heart failure (HF), and hospitalization.
- Trial name
- NCT03830814
- Testing
- Echocardiography
- Volunteers
- 100 people
- Sponsor
- The Young Investigator Group of Cardiovascular Research
Peripheral Vascular Disease
Evaluation of the Effect of the Flowaid Device in Increasing Local Circulation in the Leg
This is an open label pilot study to evaluate the efficacy and the safety of the Flowaid device in increasing local circulation in the legs.
- Trial name
- NCT00538226
- Testing
- External Electric Muscle Stimulation
- Where
- United States
- Sponsor
- Rosenblum, Jonathan I., DPM
Alzheimer Disease
Pharmacological Enhancement of Glymphatic Function in Humans
Alzheimer's disease is linked in part to the buildup of harmful proteins in the brain, including amyloid and tau. Most current treatments aim to remove these proteins directly.
- Trial name
- NCT07432997
- Testing
- Dexmedetomidine, Dexmedetomidine and Midodrine
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Applied Cognition
Sarcopenia
PNF Versus Conventional Exercise in Older Women at Increased Risk of Sarcopenia
Age-related declines in muscle strength and physical performance may impair balance, mobility, and independence in older adults.
- Trial name
- NCT07741786
- Testing
- Conventional Exercise Program, Proprioceptive Neuromuscular Facilitation Exercises
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Uşak University
Adult Stem Cell Proliferation
Exercise and NutraStem (NT-020): Effects on Stem Cells
The purpose of this study is to see if an investigational supplement called NutraStem® will increase the amount of stem cells in human blood at rest and after exercise.
- Trial name
- NCT01847027
- Testing
- NutraStem
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of North Texas Health Science Center
Acute Myocardial Infarction
Pravastatin for Acute Myocardial Infarction With Minimally to Mildly Increased Levels of Serum Cholesterol Study
The purpose of the Study is to determine whether early treatment with pravastatin can reduce adverse cardiac events in patients with acute myocardial infarction and minimally to mildly elevated serum Low Density Lipoprotein…
- Trial name
- PRACTIC (NCT00688922)
- Testing
- Pravastatin
- Where
- 9 sites in Japan
- Volunteers
- 400 people
- Sponsor
- Osaka Acute Coronary Insufficiency Study Group
Pemphigus, Bullous Pemphigoid
Human Leukocyte Antigen Class II (DRB1 and DQB1) Alleles and Haplotypes Frequencies in Patients With Pemphigus Vulgaris Among the Russian Population
Pemphigus is a rare autoimmune life-threatening blistering condition affecting skin and mucous membranes. Pemphigus belongs to a family of polygenic disorders.
- Conditions
- Pemphigus, Bullous Pemphigoid, Stevens-Johnson Syndrome, Toxic Epidermal Necrolyses
- Trial name
- NCT05284929
- Testing
- A single blood sample for HLA typing
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sechenov University
Emotional Processing, Mood
Combined Blood Pressure Medication and Activity Scheduling for Low Mood
This study explores the effects of 7-day losartan (50mg) versus placebo with brief behavioural activation on emotional processing in young volunteers low in positive mood
- Trial name
- NCT07017023
- Testing
- Losartan with BA
- Where
- United Kingdom
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Healthy Volunteers
The Effects of Increased Central Serotonergic Activity on Information Processing
It is of great clinical relevance to know if selective serotonin re-uptake inhibitors affect information processing. Our hypothesis was that aspects of information processing would be disturbed whereas others would improve.
- Trial name
- NCT00206934
- Testing
- Escitalopram, escitaolpram
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Lung Cancer Patients
Effect of Mobile Augmented Reality Counseling on Improving Shared Decision-Making in Thoracic Surgery
This randomized clinical trial evaluates the effectiveness of Mobile Augmented Reality (MAR) counseling compared to traditional verbal counseling for patients undergoing thoracic surgery.
- Trial name
- NCT07062393
- Testing
- Traditional Counseling → MAR Counseling, MAR Counseling → Traditional Counseling
- Where
- Taiwan
- Volunteers
- 47 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Intracranial Pressure Increase, Supraglottic Airway Device
Effect of Different Supralottic Airway Devicess on Optic Nerve Sheath Diameter
Direct laryngoscopy and tracheal intubation are associated with increases in intraocular pressure (IOP), intracranial pressure (ICP), heart rate (HR), and blood pressure.
- Conditions
- Intracranial Pressure Increase, Supraglottic Airway Device, Optic Nerve Sheath Diameter
- Trial name
- NCT05499754
- Testing
- pLMA: PROSEAL LARYNGEAL MASK, sLMA : SUPREMA LARYNGEAL MASK, I-jel =I-GEL
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Oesophageal Cancer
Effects of Increased Physical Activity Before Thoracoabdominal Esophageal Surgery
Thoracoabdominal oesophageal resection for cancer is a procedure with high risks for complications, and patients' preoperative status is a crucial factor for outcome.
- Trial name
- NCT03452319
- Testing
- Pretraining, Usual care
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University
Breast Cancer, Adherence, Medication
Text Messaging in Patients on Adjuvant Endocrine Therapy for Breast Cancer
1. The primary objective is to compare rates of persistence (continuation) of any endocrine therapy (ET) between patients assigned to standard of care follow-up (control arm) versus standard of care plus a bi-directional text…
- Conditions
- Breast Cancer, Adherence, Medication, Side Effect
- Trial name
- NCT03949270
- Testing
- BETA-Text text messaging intervention
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Yale University
Diabetes Mellitus, Diabetes Mellitus, Type 1
Home Testing of Day and Night Closed Loop With Pump Suspend Feature
The main study objective is to determine whether day and night automated closed loop glucose control combined with pump suspend feature will improve glucose control and reduce the burden of hypoglycaemia compared to sensor…
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 1, Glucose Metabolism Disorders, Endocrine System Diseases
- Trial name
- APCam11 (NCT02523131)
- Testing
- FlorenceM, Medtronic insulin pump 640G
- Where
- 8 sites in United States, United Kingdom
- Volunteers
- 84 people
- Sponsor
- University of Cambridge
Healthy Subjects
Effects of Increased Muscle Mass on Resting Metabolic Rate
Healthy males are randomized to isometric exercise for three months with either extra protein or extra calories in the form of a fast food meal/day in order to study if increase in muscle mass increases resting metabolic rate and…
- Trial name
- NCT01325038
- Testing
- Isometric exercise
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Augmented Reality, Cardiac Catheterization
Exploring the Effects of Augmented Reality Educational Videos on Anxiety in Patients Undergoing Cardiac Catheterization
This study investigates the effectiveness of augmented reality educational videos in improving anxiety among patients undergoing cardiac catheterization. The study participants were patients undergoing cardiac catheterization.
- Conditions
- Augmented Reality, Cardiac Catheterization, Anxiety
- Trial name
- NCT07677943
- Testing
- Augmented Reality, Paper-based education
- Where
- Taiwan
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Vegetables, Cardiovascular Disease
Clinical Investigation on the Effects of a Vegetable Juice Treatment
The purpose of the investigators study is to investigate the impact of a commercial vegetable juice on dietary vegetable intake and select cardiovascular risk factors in a generally healthy population.
- Conditions
- Vegetables, Cardiovascular Disease, Blood Pressure
- Trial name
- NCT01161706
- Testing
- Vegetable Juice
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Performance Enhancement, Athlete
Augmented Feedback Effects on Shoulder Rotator Performance
The existing literature demonstrates that motor learning strategies are effective in enhancing sports performance. One of these strategies, augmented feedback, is widely used in athletic training to help athletes achieve their…
- Conditions
- Performance Enhancement, Athlete, Shoulder
- Trial name
- NCT07510893
- Testing
- Augmented Feedback
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Elif Turgut
Increased Metabolic Requirement, Healthy
Effect of Non-essential Amino Acids on Protein Requirements for Endurance Athletes
Protein requirements in individuals who participate in endurance-based exercise training have been suggested to be greater than the current recommended dietary allowance (RDA).
- Trial name
- EA3 (NCT02874638)
- Testing
- BASE egg protein, BCAA-enriched egg protein, small amount of essential amino acids
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Toronto