Clinical trials: Effects, Longterm
Multiple Sclerosis
Retrospective Observational Study About Long-term Effect of Fampridine in Patients With Multiple Sclerosis
Mobility problems in multiple sclerosis (MS) is a frequent symptom. It might appear in almost 93% of patients in the first 15 years of the disease, being a clear problem for their normal living.
- Trial name
- RETROFAM (NCT02966808)
- Testing
- cognitive and behavioural questionnaires
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Hearing Impaired
Educational Program for Hearing Aid Users With Internet Support
The purpose of this study is to examine the short-term effects of complementing an educational program for hearing aid users with Internet support.
- Trial name
- NCT01837550
- Testing
- Intervention group, Control group
- Where
- Sweden
- Volunteers
- 74 people
- Sponsor
- Sodra Alvsborgs Hospital
Cancer Pain
Long-term Effects of Methadone for Cancer Pain
The methadone is an useful opioid for the cancer pain treatment, mostly used in second or last line during the opioid rotation. The Methadone had an anti-MNDA effect, and clinicians agree that the methadone could have an effect…
- Trial name
- NCT02856399
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
β-Thalassemia
Extension Study to Evaluate the Safety and Efficacy of Luspatercept in Participants With β-Thalassemia Previously Enrolled in A536-04 (A536-06/MK-6143-004)
Study A536-06 (MK-6143-004) is an open-label extension study for participants previously enrolled in study A536-04 (NCT01749540), to evaluate the long-term safety and tolerability of luspatercept in adult participants with…
- Trial name
- NCT02268409
- Testing
- luspatercept
- Where
- 7 sites in Greece, Italy
- Volunteers
- 51 people
- Sponsor
- Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA
Primary Progressive Aphasia(PPA)
Long Term Effect of Brain Stimulation in PPA
The goal of this clinical trial is to investigate the effect of non-invasive brain stimulation techniques in the progression of primary progressive aphasia for 6 months.
- Trial name
- RECONNECT-PLUS (NCT07158216)
- Testing
- TMS, tDCS
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital San Carlos, Madrid
Long-Term Effects Secondary to Cancer Therapy
Tumor Nutritional Therapy in the First-line Treatment of Stage IV NSCLC
A Single-center, Randomized, Controlled Clinical Study Comparing the Efficacy and Safety of Tumor Nutritional Therapy Combined With Immune Checkpoint Inhibitors and Chemotherapy in the First-line Treatment of Stage IV NSCLC…
- Trial name
- NCT06356701
- Testing
- Cancer nutritional treatment regimen (Spirulina Bifidobacterium Capsules, Fish Oil Grape Seed Blueberry Soft Capsules, Ganoderma Spore Oil Soft Capsules)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Nutrition, Healthy
Acute and Long-term Health Effects of Various Carbohydrates on Blood Glucose Management in Humans
Dietary fibre, especially soluble fibre, has several health benefits such as lowering the risks for cardiovascular disease, stroke, diabetes, obesity, and gastrointestinal diseases.
- Trial name
- NCT06554002
- Testing
- Control, Treatment
- Where
- Singapore
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Anxiety Disorder, Head and Neck Cancer
Study of Anxiety and Avoidance of Others in Patients Previously Treated for Head and Neck Cancer
RATIONALE: Patients who undergo treatment for head and neck cancer may become anxious and avoid contact with other people. Learning how cancer treatment may cause anxiety in patients with head and neck cancer may help improve the…
- Conditions
- Anxiety Disorder, Head and Neck Cancer, Lung Cancer
- Trial name
- NCT00483639
- Testing
- Medical chart review, Liebowitz Social Anxiety Scale and the Social Phobia and Anxiety Inventory, management of therapy complications
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Obstructive Sleep Apnea, Coronary Heart Disease
Long-term Effects of CPAP on Lipidemia and Hs-CRP Levels in OSA Patients
The increased risk of atherosclerotic morbidity and mortality in patients with obstructive sleep apnea (OSA) has been linked to hypertension, insulin resistance, dyslipidemia, and systemic inflammation.
- Trial name
- NCT02127177
- Testing
- Continuous Positive Airway Pressure Ventilator
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Chinese Pulmonary Vascular Disease Research Group
Preterm Birth, Child Development
Omega Tots Long Term Follow-up
This is a continuation study to the Omega Tots trial (NCT01576783). The purpose of this study is to follow-up with participants of the original study to determine the long-term effect a daily fatty acid dietary supplement taken…
- Trial name
- NCT05191823
- Testing
- Docosahexaenoic Acid + Arachidonic Acid (DHA+AA)
- Where
- United States
- Volunteers
- 377 people
- Sponsor
- Sarah Keim
Radial Artery, Ultrasound
Long-term Effects of Radial Artery Cannulation on Vessel Diameter, Blood Flow and Fine Motor Skills
This observational study examined changes in blood vessel diameter, blood flow, and fine motor performance after ultrasound-guided radial artery cannulation in adults undergoing elective cardiac surgery.
- Conditions
- Radial Artery, Ultrasound, Fine Motor Skills
- Trial name
- NCT06975566
- Testing
- radial artery catheterization
- Volunteers
- 103 people
- Sponsor
- Kartal City Hospital
Kidney Transplantation
Long-Term Effect of Soy Consumption on Cardio-Renal Indices and CRP in Type 2diabetes With Nephropathy
we conducted a longitudinal 4-year clinical trial to determine the long-term effects of soy consumption on lipid profiles, renal-function indices and CRP level among type 2 diabetic patients with nephropathy.
- Trial name
- NCT00555490
- Testing
- Soy protein
- Volunteers
- 41 people
- Sponsor
- Isfahan University of Medical Sciences
Metabolic Syndrome
Effect of High-dose Pitavastatin on Glucose Control in Patients With Metabolic Syndrome
This purpose of this study is to evaluate effect of high-dose Pitavastatin on glucose control in patients with metabolic syndrome.
- Trial name
- NCT02940366
- Testing
- Pitavastatin 4 mg orally daily, Atorvastatin 20 mg orally daily
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Seoul National University Hospital
Breast Cancer
Short and Long Term Effects of a Physical Therapy Program After Breast Cancer Surgery
Objectives: To evaluate the pressure pain threshold, shoulder biomechanics, cardiorespiratory function and the quality of life associated with the short and long-term physical therapy rehabilitation following breast cancer…
- Trial name
- NCT04116281
- Testing
- Rehabilitation after breast cancer surgery
- Where
- Chile
- Volunteers
- 36 people
- Sponsor
- Universidade Federal de Sao Carlos
Type 2 Diabetes Mellitus
Extension Study for 2993-112
This multicenter, open-label extension study of Protocol 2993-112 is designed to assess long-term glucose control as measured by HbA1c (glycosylated hemoglobin) and to evaluate long-term safety and tolerability in subjects…
- Trial name
- NCT01789957
- Testing
- AC2993
- Where
- 226 sites in United States, Canada
- Volunteers
- 225 people
- Sponsor
- AstraZeneca
Metabolic Health
Effects of Exercise During Pregnancy on the Long-term Metabolic Health of Mothers and Their Offspring
The aim of this study was to assess the long-term metabolic effects of gestational exercise on overweight and obese women and their offspring 8-10 years post-intervention.
- Trial name
- NCT07435857
- Testing
- exercise
- Where
- China
- Volunteers
- 221 people
- Sponsor
- Peking University First Hospital
Nocturnal Enuresis
Nocturnal Enuresis and Rapid Maxillary Expansion
Nocturnal enuresis (NE) is the involuntary loss of urine that occurs only at night in children aged 5 years or more. NE is a common problem, affecting about 10% of school children.
- Trial name
- NERME (NCT02178826)
- Testing
- Rapid Maxillary Expansion
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Uppsala University Hospital
Myelofibrosis
A Long-Term Study of the Effects of Orally Administered SAR302503 in Patients With Myelofibrosis
The purpose of this study is to evaluate the long-term effects of orally administered SAR302503 (TG101348) in patients with myelofibrosis who have completed the MF-TG101348-001 study.
- Trial name
- NCT00724334
- Testing
- SAR302503 (TG101348)
- Where
- 6 sites in United States
- Volunteers
- 43 people
- Sponsor
- Bristol-Myers Squibb
Sepsis
A Study on How the Immune System Responds to Sepsis and Its Long-term Effects
Sepsis occurs when an infection, caused by bacteria, a virus, or a fungus, enters the body and throws the immune system out of balance.
- Trial name
- HEAL-SEPSIS (NCT07273344)
- Testing
- blood sampling
- Where
- Netherlands
- Volunteers
- 400 people
- Sponsor
- Radboud University Medical Center
Diabetes Mellitus, Type 2
Long-Term Effects of Insulin Plus Metformin Regimens on the Overall and Postprandial Glycemic Control of Patients With Type 2 Diabetes
The primary objective of this study is to show that a prandial insulin regimen, consisting of premeal insulin lispro "mid mixture" (or a combined regimen of insulin lispro "mid mixture" and insulin lispro "low mixture") plus…
- Trial name
- NCT00191464
- Testing
- premeal insulin lispro mixtures, insulin glargine, metformin
- Where
- 7 sites in United States, Australia and 5 more
- Volunteers
- 320 people
- Sponsor
- Eli Lilly and Company