Clinical trials: Effects, Longterm
Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission
Internet-Based Program With or Without Telephone-Based Problem-Solving Training in Helping Long-Term Survivors of Hematopoietic Stem Cell Transplant Cope With Late Complications
RATIONALE: A personalized Internet-based program may help improve fatigue, depression, and quality of life in long-term survivors of stem cell transplant.
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities
- Trial name
- NCT00799461
- Testing
- internet-based intervention, questionnaire administration, psychosocial assessment and care
- Where
- United States
- Volunteers
- 1,337 people
- Sponsor
- Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
Percutaneous Coronary Intervention
Short Term and Long Term Effects of Single Stent and Embedded Balloon Angioplasty in the Treatment of Coronary Bifurcation Lesions
At the same time in the side branch stent expansion vessels were embedded and balloon dilatation technique in for Medina1.1.1 type, 1.0.1 type or 0.1.1 type lesions of interventional therapy for bifurcation lesions, the PCI…
- Trial name
- NCT02691819
- Testing
- single stent and embedded balloon angioplasty
- Where
- China
- Volunteers
- 60 people
- Sponsor
- ZhangWenduo
Anaemia
Long Term Effect of Early Iron Supplementation and Psychosocial Stimulation on Growth and Development of Iron-deficient Anaemic Infants
1. Burden: Anaemia is a public health problem in our country. Fifty one percent young children aged 6 to 59 months are suffering from anaemia in Bangladesh (BDHS-2011) and the main cause of this problem is iron deficiency.
- Trial name
- NCT02801721
- Testing
- psycho social stimulation
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Relapsing Remitting Multiple Sclerosis
Long-term Effect of Fingolimod on Circulating Immunocompetent Mononuclear Cells in Patients With Multiple Sclerosis
The purpose of this study is to explore immunomodulatory and immunosuppressive mechanisms of action of fingolimod in patients with Relapsing remitting multiple Sclerosis to collect data on biomarkers after initiation of…
- Trial name
- BiobankII (NCT01755871)
- Testing
- Fingolimod
- Where
- Germany
- Volunteers
- 8 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Training, Intensive Care (ICU)
Enteral Nutrition Education Provided Using the Pecha Kucha Method
Enteral nutrition therapy is essential to prevent or treat malnutrition, reduce infection complications, shorten recovery and hospital stay, and lower hospital costs and mortality rates.
- Conditions
- Training, Intensive Care (ICU), Nurses
- Trial name
- NCT07511322
- Testing
- Pecha Kucha Method Training
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Acute Pain
Acute Pain Episodes in Patients Under Opioid Maintenance Therapy : Clinical Management and Long Term Effects
To define a rational pharmacological management of pain for the subjects under opioid maintenance therapy (methadone or buprenorphine), it is first of all necessary to estimate the efficiency of the current practices on pain…
- Trial name
- NCT00738036
- Where
- France
- Volunteers
- 151 people
- Sponsor
- University Hospital, Toulouse
Parkinson's Disease
ADAGIO Follow Up Study: Evaluation of the Long-Term Effects of Rasagiline in Parkinson's Disease Subjects
Eligible participants, who participated in the ADAGIO trial and who sign an approved informed consent form, will be enrolled into the study at their original study locations.
- Trial name
- NCT00936676
- Testing
- rasagiline mesylate
- Where
- 102 sites in United States, Argentina and 11 more
- Volunteers
- 684 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Sport-related Concussion
Sub-acute Exercise Following Sport-Related Concussion
Determine the safety and efficacy of sub-maximal aerobic exercise during the subacute phase of recovery following sport-related concussion.
- Trial name
- NCT03575455
- Testing
- Exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Florida State University
Long-term Effects Secondary to Cancer Therapy in Children, Lymphoma
Long-Term Effects of Treatment in Patients Previously Treated for Childhood Hodgkin's Lymphoma
RATIONALE: Assessing the long-term effects of cancer treatment in cancer survivors may help improve the ability to plan effective treatment and follow-up care.
- Trial name
- NCT00091091
- Testing
- medical chart review, questionnaire administration, management of therapy complications
- Where
- 15 sites in United States
- Volunteers
- 530 people
- Sponsor
- Children's Oncology Group
Actinic Keratosis
Long-term Effects of Imiquimod and Diclofenac in Actinic Keratoses (LEIDA 2)
This clinical trial serves the purpose to compare the long-term effects of a treatment of actinic keratosis - your skin disorder - using Aldara® 5% cream (Imiquimod) or Solaraze® 3% gel (Diclofenac) on the face or the scalp.
- Trial name
- LEIDA 2 (NCT01453179)
- Testing
- Imiquimod, Diclofenac
- Where
- 17 sites in Austria, Germany
- Volunteers
- 221 people
- Sponsor
- MEDA Pharma GmbH & Co. KG
Dry Eye
Long-term Effects of Acoltremon vs. Control in Dry Eye Disease
This is a prospective, longitudinal, single-center study designed to evaluate the long-term changes in symptoms and tear production in subjects with dry eye disease.
- Trial name
- NCT07659626
- Testing
- Acoltremon 0.003%, Refresh classic preservative free
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Eye Care Institute
Aging
CALERIE (Tufts) - Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy
This study is one of three CALERIE trials that test the hypothesis that a reduced calorie, nutritionally sound diet increases the length of life and prevents some age-related chronic diseases such as cancer, diabetes, and…
- Trial name
- NCT00099099
- Testing
- Caloric Restriction (CR)
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Vitamin D Deficiency, Low Bone Density
Nursing-Home Residents Given Bread Fortified With Vitamin D3
Background. For older adults, serum 25-hydroxyvitamin D (25(OH)D) higher than 75 nmol/L lowers fracture risk and attainment of this 25(OH)D target may require 125 mcg (5000 IU)/d of vitamin D3.
- Trial name
- NCT00789503
- Testing
- Bread fortified with vitamin D3 and calcium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Low Tension Glaucoma
Observational Study of the Long-term Effect of Latanoprost in Normal Tension Glaucoma
The purpose of this study is to assess the long-term efficacy and safety of latanoprost monotherapy in patients with normal tension glaucoma (NTG) using a prospective, observational design.
- Trial name
- NTG-X-PERT (NCT01209624)
- Volunteers
- 902 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Anterior Cruciate Ligament Reconstruction
Neurophysiologic Correlates of Movement Planning During Complex Jump Landing Tasks and the Role of Cognitive Function
To examine the long-term effects of anterior cruciate ligament injuries and reconstructions (after successful rehabilitation) on cortical processes of motor planning during complex jump landing tasks and the relevance of…
- Trial name
- NCT03336060
- Testing
- Cortical Correlates of Jump Landing Task
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Goethe University
Frailty, Critical Illness
Prevalence and Long Term Effects of Frailty in Elderly Intensive Care Patients
The primary aim is to study change of critical frailty scale (CFS) and health related quality of life (EQ-5D-5L) in a long-term follow-up of ICU survivors.
- Trial name
- SkrInt (NCT06012942)
- Where
- 5 sites in Norway
- Volunteers
- 300 people
- Sponsor
- University Hospital of North Norway
Diabetes Mellitus, Type 2
Effects of Physical Activity Coaching on Health and Behaviour Parameters in Diabetic Persons
In this project the investigators like to develop a methodology to stimulate more physical activity in inactive diabetic persons by an adapted physical activity program.
- Trial name
- NCT02064335
- Testing
- Physical activity coaching
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Premature Birth
Family Nurture Intervention (FNI) in Neonatal Intensive Care Unit (NICU)
The purpose of this study is to test the efficacy of a family nurture intervention in the neonatal intensive care unit (NICU). Infants receiving enhanced mother-infant and family nurture are compared to infants receiving standard…
- Trial name
- NCT01439269
- Testing
- Family Nurture Intervention
- Where
- United States
- Volunteers
- 394 people
- Sponsor
- Columbia University
Epiretinal Membrane
Epiretinal Fibrosis, Effect of Early Surgery
The goal of this randomized clinical trial is to investigate when it is optimal to treat the eye disease epiretinal fibrosis. Hypothesis: In a population of patients with symptomatic idiopathic epiretinal fibrosis and visual…
- Trial name
- epitell (NCT00902629)
- Testing
- Early surgery
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- Glostrup University Hospital, Copenhagen
CLL, Vaccine Response
Immune Response After Pneumococcal Vaccination in Patient With Chronic Lymphocytic Leukemia
A randomized, multi-centre trial was conducted between 2013-2016, including 128 patients with untreated CLL from eight hematological clinics in Sweden.
- Trial name
- NCT05316831
- Testing
- PCV13, PPSV23
- Where
- Sweden
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Region Örebro County