Clinical trials: Elder
Diabetes Mellitus, Microbiome
Supplementation of Inulin + L. Acidophilus in Elders With T2DM
This study investigates the effects of a symbotic supplement (Inulin + Lactobacillus acidophilus) on cognitive impairment in older adults with type 2 diabetes mellitus (T2DM).
- Conditions
- Diabetes Mellitus, Microbiome, Cognition Disorders
- Trial name
- NCT06830824
- Testing
- Lactobacillus acidophilus
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Anahuac University
Visual Acuity
Ophthalmologic Examinations After Infusion of ZK200775
ZK 200775 is an antagonist at the α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor and had earned attention a possible neuroprotective agent in cerebral ischemia.
- Trial name
- NCT00999284
- Testing
- ZK200775, Sodium Chloride
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Hearing Loss
Aging, Cognition, and Hearing Evaluation in Elders Study
The investigators will conduct a small pilot study that will randomize ~ 40 70-84 year-old adults with hearing loss to best-practices hearing rehabilitative treatment (hearing assessment, counseling, fitting of amplification…
- Trial name
- ACHIEVE-P (NCT02412254)
- Testing
- Best practices hearing rehabilitative treatment, Successful aging intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
High Intensity Exercise, Normal Cognition
CYCLE-AD (CYcling to Cease or Limit the Effects of Alzheimer's Disease)
The overall goal of the CYCLE-AD trial is to determine the role of long-term, high intensity exercise in slowing or delaying the onset of cognitive and AD-related brain changes in e4 carriers.
- Conditions
- High Intensity Exercise, Normal Cognition, Exercise Intervention
- Trial name
- CYCLE-AD (NCT04748861)
- Testing
- Indoor Cycling (IC)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Advance Care Planning
I Kua na'u Advance Care Planning for Native Hawaiian Elders
Communication surrounding serious illness decision making is formalized in Advance Care Planning (ACP), a process involving verbal or written information designed to inform patients of possible medical options including…
- Trial name
- NCT04771208
- Testing
- I kua na'u "Let Me Carry Out Your Last Wishes"
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Stress
Education Program for Family Caregivers
The purpose of this evaluation was to determine the effectiveness of an educational program designed to assist family caregivers to learn the knowledge and skills to take better care of their frail elder relatives and themselves.
- Trial name
- NCT00764647
- Testing
- Education program for family caregivers of frail elders
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- CAMC Health System
Depression, Anxiety, Fatigue
Feasibility Study of a Modified Yoga Program for Elders
The purpose of this study is to determine whether a modified yoga program helps improve pain and function in elders age 65 years or older living in an assisted living community.
- Conditions
- Depression, Anxiety, Fatigue, Pain, Chronic, Sleep
- Trial name
- NCT04343625
- Testing
- Modified yoga class
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Functional Fitness, Health Promotion
12-week Pilates Program on Community-dwelling Middle-aged Women
The purpose of this study was to investigate the effects of a Pilates exercise intervention program on functional physical fitness in community-dwelling middle-aged women.
- Conditions
- Functional Fitness, Health Promotion, Exercise, Frail Elderly Syndrome
- Trial name
- NCT05333484
- Testing
- Programed Pilates
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Pneumococcal Infections
Immunogenicity and Reactogenicity of Pneumococcal Polysaccharide and Conjugate Vaccines in Native Elders
To test the hypothesis that immune responses to 23-valent pneumococcal polysaccharide vaccine (PPV-23) could be improved in Alaska Native elders by immune priming with 7-valent pneumococcal conjugate vaccine (PCV-7), we assessed…
- Trial name
- NCT00153543
- Testing
- PCV7 + PPV23, 2 months, PCV7 + PPV23, 6 months
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Aging, Alzheimer's Disease
Effects of Exercise and Cognitive Training on Cognitive Function in Older Adults
The purpose of this study is to gain a better understanding of the effects of exercise and cognitive training on improving brain function in healthy older adults who may be at risk for developing Alzheimer's Disease.
- Trial name
- NCT01038726
- Testing
- Exercise Training, Cognitive Training, Flexibility Training
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Frailty
Effect of an Oral Frailty Measures Intervention Programs in Institutionalized Elders
This is a compelling 16-week prospective, double-blind, whole-cluster randomized controlled trial(RCT).This study will recruit 226 older adults over the age of 65.Based on King's goal attainment theory, a program to promote oral…
- Trial name
- NCT06536985
- Testing
- treatment group, Contral group
- Where
- China
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Hangzhou Normal University
Muscular Atrophy, Sensitivity Training Groups
Effects of Inspiratory Muscle Training in Elders
Aging causes anatomical and physiological changes in the respiratory system and respiratory muscle strength with decline in its maximum function.
- Conditions
- Muscular Atrophy, Sensitivity Training Groups, Aging
- Trial name
- NCT01791010
- Testing
- Inspiratory muscle training
- Where
- Brazil
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Dementia, Caregivers
The Balance Study Balancing Life and Reducing Stress For Those Providing Elder Care
The primary goals of this exploratory/developmental (R21) study are to evaluate the feasibility and acceptability of a MBSR intervention for caregivers of patients with dementia, and to estimate the effectiveness of program…
- Conditions
- Dementia, Caregivers, Stress
- Trial name
- Balance (NCT00615082)
- Testing
- Mindfulness-Based Stress Reduction, Caregiver Education & Social Support
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Elder Abuse
A Path to Prevention of Elder Abuse in Long-term Care. General Population Prevalence Study
The goal of this cross-sectional study is to learn about how common experiences of different forms of abuse are among people over the age of 65 years in Sweden.
- Trial name
- APPEAL (NCT06786065)
- Testing
- No intervention (observational study)
- Where
- Sweden
- Volunteers
- 7,727 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Elderly
Eldercare Technology in a Silver Culture Village
The aim of this project is to create ten smart devices that involve combining an interactive art environment with IC technology, arts and health administration.
- Trial name
- NCT03084107
- Testing
- Questionnaire
- Where
- Taiwan
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Sarcopenia in Elderly, Tai Chi
The Effect of Tai Chi Exercise Among Elders With Sarcopenia
Sarcopenia has been defined as a disease which presented as low muscles strength, low muscle quantity or quality and low physical activity.
- Trial name
- NCT05145036
- Testing
- Tai-Chi, Comprehensive training
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Dialectical Behaviour Therapy
Pathways to Care-Understanding the Impact of an Indigenous Elder Co-lead in Perinatal Dialectical Behaviour Therapy
To integrate traditional Indigenous Knowledge with gold-standard therapy to enrich the patient experience from an anti-oppressive, culturally safe perspective for marginalized individuals with psychosocially complex pregnancies.
- Trial name
- NCT06466694
- Testing
- Modified Dialectical Behavioural Therapy
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Dementia
PLAN: Dementia Literacy Education and Navigation for Korean Elders With Probable Dementia and Their Caregivers
Early detection of dementia allows for a transition to early dementia care that may delay or slow deterioration of cognitive functions and functional disabilities and enable families to adequately plan for the potential…
- Trial name
- PLAN (NCT03909347)
- Testing
- PLAN, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 574 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Multimodal Intervention, Fragility
Effectiveness of a Multi-component Physical Training in Hyper-fragile Elders: A Randomized Clinical Trial
Objective: To compare short-term and medium-term effectiveness of a multimodal program that integrates a program of therapeutic exercise, medication review, adequacy of diet and health education, compared with standard medical…
- Conditions
- Multimodal Intervention, Fragility, Other Metabolic Diseases, Physical Activity
- Trial name
- PowerA-01 (NCT02772952)
- Testing
- Control Intervention, Multimodal Intervention
- Where
- Spain
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Elder Mistreatment, Elder Abuse
Knowledge and Interpersonal Skills to Develop Enhanced Relationships (KINDER)
The Knowledge and Interpersonal Skills to Develop Enhanced Relationships (KINDER) intervention was developed to prevent psychological elder abuse (EA) and promote high-quality caregiving by lowering relationship strain and…
- Conditions
- Elder Mistreatment, Elder Abuse, Quality of Care, Dementia
- Trial name
- KINDER (NCT07216950)
- Testing
- Knowledge and Interpersonal Skills to Develop Enhanced Relationships, Healthy Living for the Caregiver
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University