Clinical trials: Elective
Elective HFOV for Respiratory Failure in Neonates/Infants, Rescue HFOV in Neonates and/Infants With Refractory Respiratory Failure Under Conventional Therapy
Servo-n HFOV Study: Safety and Performance in Neonates and Infants
The purpose of this study is to evaluate the safety and performance of High-Frequency Oscillatory Ventilation (HFOV) modes of the Servo-n ventilator in neonates and infants, by using a prospective, observational, single-arm…
- Trial name
- NCT06114992
- Testing
- Servo-n HFOV modes
- Where
- 4 sites in France, Poland and 1 more
- Volunteers
- 83 people
- Sponsor
- Maquet Critical Care AB
Elective Surgery Requiring Laryngeal Mask Airway General Anesthesia
ED90 of Tegileridine Combined With Propofol for LMA Insertion
This is a prospective two-group dose-finding trial using biased-coin sequential up-and-down design. We plan to enroll 108 patients who need general anesthesia with laryngeal mask airway placement, divided into young group (18-64…
- Trial name
- NCT07665151
- Testing
- Tegileridine combined with Propofol for anesthesia induction
- Where
- China
- Volunteers
- 109 people
- Sponsor
- Shiyou Wei
Elective Upper Limb Surgery Distal to the Elbow
Early Detection of Ulnar Sparing After Supraclavicular Block Using Infrared Thermography and Perfusion Index
Aim of the Study The aim of this study is to evaluate the effectiveness of early temperature changes measured by infrared thermography and perfusion index monitoring in predicting ulnar nerve sparing following ultrasound-guided…
- Trial name
- NCT07745985
- Testing
- Supraclavicular Block
- Volunteers
- 92 people
- Sponsor
- Fayoum University
Postpartum Hemorrhage, Uterine Atony
Oxytocin Bolus Versus Infusion in High-Risk Patients Undergoing Elective Cesarean Section (INBOX-HR)
The goal of this randomized, double-blind clinical trial is to learn if Oxytocin is most effective at achieving adequate uterine tone (important for preventing postpartum hemorrhage) when administered as a bolus or an infusion in…
- Conditions
- Postpartum Hemorrhage, Uterine Atony, Uterine Atony With Hemorrhage, Elective Cesarean Section
- Trial name
- INBOX-HR (NCT07688512)
- Testing
- Oxytocin Bolus or Oxytocin Infusion
- Volunteers
- 180 people
- Sponsor
- Stony Brook University
Undergo Elective Cardiac Surgery, Cardiopulmonary Bypass
Evaluation of the Effectiveness of Ultrasound-Guided Stellate Ganglion Block in Cardiac Surgery Anesthesia on Postoperative Recovery
Heart surgery is a complex and delicate procedure that affects more than one million people worldwide each year. Patients who undergo this surgery are generally elderly and have multiple comorbidities, which places them in…
- Conditions
- Undergo Elective Cardiac Surgery, Cardiopulmonary Bypass, CPB
- Trial name
- ECLAIR (NCT07676487)
- Testing
- Elective surgery (≥ 24 hours) with cardiopulmonary bypass (more than 2 procedures)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Tracheal Intubation, Elective Surgery, Tracheal Diamater Measurement
Ultrasound Measurement of Skin-to-Epiglottis Distance for Prediction of Difficult Airway in Adult Patients
This prospective observational study aims to evaluate the predictive value of ultrasound-measured skin to epiglottis distance for difficult airway in adult patients undergoing elective or emergency procedures requiring airway…
- Conditions
- Tracheal Intubation, Elective Surgery, Tracheal Diamater Measurement, Ultrasound Evaluation of Airway
- Trial name
- NCT07609147
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Hacettepe University
Elective Cesarean Delivery
Administration Of Calcium Gluconate for The Reduction of Blood Loss During Elective Cesarean Delivery
Postpartum hemorrhage (PPH) is the leading cause of death related to pregnancy. PPH can lead to blood transfusion, disseminated intravascular coagulation (DIC), hysterectomy, or death.
- Trial name
- NCT06235749
- Testing
- Calcium Gluconate 10%, sodium chloride 0.9%
- Where
- 4 sites in Israel
- Volunteers
- 1,180 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Intensive Care Unit, Coronary Artery Bypass Grafting (CABG)
Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients
The MODIFY CSX study is a prospective, randomized, placebo-controlled trial conducted in heart centers in Germany and Italy. A total of 550 high-risk cardiac surgery patients will receive either 0.20 g fish oil/kg body weight…
- Conditions
- Intensive Care Unit, Coronary Artery Bypass Grafting (CABG), High Risk Patients, Cardiopulmonary Bypass
- Trial name
- MODIFY CSX (NCT06279793)
- Testing
- Fish Oil, Intravenous 0.9% Sodium Chloride
- Where
- 10 sites in Germany
- Volunteers
- 550 people
- Sponsor
- GCP-Service International West GmbH
Adult Patients Aged 19-64, Scheduled for Elective Arthroscopic Knee Surgery
Effect of Nociception Level Monitoring During Remimazolam-based Total Intravenous Anesthesia on Intraoperative Opioid Requirements and Postoperative Pain
This study aims to investigate whether the use of nociception monitoring during general anesthesia with remimazolam-based total intravenous anesthesia has an effect on intraoperative opioid requirements and postoperative pain.
- Trial name
- NCT05615441
- Testing
- Analgesia Nociception Index monitor, Standard monitoring
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Yonsei University
Childbirth Education, Birth Beliefs
Effect of Pecha Kucha-Based Normal Birth Education on Birth Beliefs and Birth Preferences Among Pregnant Women Considering Elective Cesarean Section
This randomized controlled trial was conducted to evaluate the effect of Pecha Kucha-based normal birth education on birth beliefs and mode of birth preferences among primiparous pregnant women considering elective cesarean…
- Conditions
- Childbirth Education, Birth Beliefs, Elective Cesarean Section
- Trial name
- NCT07657663
- Testing
- Pecha Kucha-Based Normal Birth Education, Traditional Normal Birth Education
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Burdur Mehmet Akif Ersoy University
Nerve Conduction Study, Elective Surgery
Median Nerve Electromyography to Monitor Intraoperative Neuromuscular Function
The effect of muscle relaxants need to be followed during surgery and before waking up the patient, the anesthesiologist has to make sure that the effect of muscle relaxants is gone.
- Conditions
- Nerve Conduction Study, Elective Surgery, Neuromuscular Monitoring After Administration of Neuromuscular Blocking Agents in Different Types of Surgery
- Trial name
- NCT07571395
- Testing
- Electromyography
- Where
- Hungary
- Volunteers
- 45 people
- Sponsor
- Pongrácz Adrienn
Elective Colon Surgery
Comparing No Mechanical Bowel Preparation With Oral Antibiotics Alone in Patients Undergoing Elective Colon Surgery
The REaCT NSQIP will compare oral antibiotics vs. no antibiotics, which are two standards of care treatments for preoperative preparation of the bowel prior to colorectal surgery
- Trial name
- REaCT-NSQIP (NCT03663504)
- Testing
- No Preparation, Neomycin and Flagyl
- Where
- 6 sites in Canada
- Volunteers
- 630 people
- Sponsor
- Ottawa Hospital Research Institute
Elective Surgical Procedures, Postoperative Pain
Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair
Open Abdominal Aortic Aneurysm (AAA) repair is a high-risk surgical procedure accompanied by intense endocrine and metabolic responses to surgical stress, with subsequent activation of the inflammatory cascade, cytokine and…
- Conditions
- Elective Surgical Procedures, Postoperative Pain, Anesthesia, Opioid Use
- Trial name
- NCT04894864
- Testing
- Opioid-Based Anesthesia-Analgesia Strategy, Opioid-free Anesthesia-Analgesia Strategy
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- University of Crete
Maternal and Fetal Outcomes in Elective vs Emergency Cesarean Section
Maternal and Fetal Outcomes in Elective vs Emergency Cesarean Section
Cesarean section (CS) rates have increased substantially worldwide and in Egypt, where they now account for the majority of deliveries. Maternal and neonatal outcomes may differ between elective and emergency CS.
- Trial name
- NCT07651241
- Testing
- emergency cesarean section, elective cesarean section
- Volunteers
- 210 people
- Sponsor
- Assiut University
Elective Colorectal Surgery
Impact of a Bridge Device on the Loop Ileostomy
During the creation of an ileostomy, a bridge device is systematically placed in an aim to reduce wound and peritoneal contamination by stools. Nevertheless no evidence was reported to justify this issue.
- Trial name
- IBIP (NCT02756273)
- Testing
- bridge device, no bridge device
- Where
- 3 sites in France
- Volunteers
- 166 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Patients Scheduled for Elective Lower Extremity Surgery, Ages 18-80
Parasacral Ischial Plane Block in Lower Extremity Surgery
The parasacral ischial plane block is a novel fascial plane approach targeting the sacral plexus. This technique is technically less challenging and eliminates the requirement for direct visualization of the sacral plexus.
- Conditions
- Patients Scheduled for Elective Lower Extremity Surgery, Ages 18-80, ASA I-III, Patients Operated on Under Regional Anesthesia
- Trial name
- NCT07594197
- Testing
- Parasacral Ischial Plan Block, Sacral plexus block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Prehabilitation, Preoperative Care
Prehabilitation Before Major Surgery
The goal of this clinical trial is to learn if a virtually monitored, home-based prehabilitation program is feasible and acceptable for adults undergoing major elective surgery. The main questions it aims to answer are: 1.
- Conditions
- Prehabilitation, Preoperative Care, Elective Surgical Procedures, Postoperative Complications
- Trial name
- PRIME (NCT07590141)
- Testing
- Virtually Monitored Home-Based Prehabilitation Program
- Where
- 3 sites in Canada
- Volunteers
- 120 people
- Sponsor
- Queen's University
Elective Surgeries, General Anesthesia
Validation of the PRST Score Against Bispectral Index
The goal of this randomized controlled trial is to evaluate whether the PRST (Evans) score is a valid method for monitoring the depth of general anesthesia in adult surgical patients.
- Conditions
- Elective Surgeries, General Anesthesia, BIS
- Trial name
- NCT07590388
- Testing
- PRST Monitoring, PRST + BIS Monitoring
- Where
- Indonesia
- Volunteers
- 183 people
- Sponsor
- Gadjah Mada University
Patients Eligible for Elective Lower Extremity Femoral Nerve Surgery, Knee Arthroscopic Surgery
Clinical Observation of Bupivacaine Liposome for Lower Extremity Nerve Block
This prospective, sequential dose-finding clinical observational study aims to estimate the median effective concentration (EC50) and the 95% effective concentration (EC95) of liposomal bupivacaine for ultrasound-guided femoral…
- Trial name
- NCT07366905
- Testing
- Liposomal bupivacaine, 266mg
- Where
- China
- Volunteers
- 79 people
- Sponsor
- Hainan Medical College
Pediatric, Elective
Laryngeal Mask Airways Are Supraglottic Devices Used to Maintain Airway Patency During Anesthesia and in Difficult Airways. IV Dexmedetomidine Improves LMA Insertion Success and Decreases Coughing, While IV Lidocaine Decreases Postoperative Cough.
Laryngeal Mask Airways Are Supraglottic Devices Used to Maintain Airway Patency During Anesthesia and in Difficult Airways. LMA may help in reducing postoperative pulmonary complications.
- Conditions
- Pediatric, Elective, Surgery in Early Childhood
- Trial name
- DEX LMA (NCT07562308)
- Testing
- Dexamedomedine, Lidocaine (drug)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University