Clinical trials: Elective
Postpartum Hemorrhage
Carbetocin at Elective Cesarean Delivery Part 2
Post-partum hemorrhage (PPH) is a major cause of maternal death worldwide. Oxytocin is the most common uterotonic drug used to prevent and treat PPH in North America, however, there are some limitations to its use.
- Trial name
- NCT01428817
- Testing
- Carbetocin
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Anesthesia, Anxiety
Media Use, Anxiety, Sedation, and Recovery in Children Having Upper GI Endoscopy
This observational study will investigate whether problematic digital media use is associated with anxiety in children undergoing a planned upper gastrointestinal endoscopy, a camera examination of the upper digestive tract.
- Trial name
- PMU-ASR-ENDO (NCT07916168)
- Testing
- Problematic Media Use
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Health Care, Drugs
Hyperbaric Bupivacaine and Hyperbaric Levobupivacaine in C/S
Aim of the Study To compare the effects of hyperbaric bupivacaine plus fentanyl with hyperbaric levobupivacaine plus fentanyl on spinal block quality, haemodynamics and need for analgesics in patients undergoing elective cesarean…
- Trial name
- NCT02025374
- Testing
- Hyperbaric levobupivacaine, Hyperbaric bupivacaine % 0.5
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Balikesir University
Elective Cardiac Surgery
Acceptable Range of Inspiratory Effort During Mechanical Ventilation
Partially assisted mechanical ventilation is ideally titrated to maintain adequate inspiratory muscle activity (i.e. preventing disuse atrophy) while avoiding excessive (i.e. fatiguing) inspiratory loads.
- Trial name
- EFFORT (NCT02838524)
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- Unity Health Toronto
Surgical Site Infection
Effect of Peritoneal Lavage With Clindamycin-gentamicin Solution on Postoperative Colorectal Cancer Infection in Elective Surgery
Intrabdominal antibiotic irrigation will reduce wound and intrabdominal infection.
- Trial name
- lavage (NCT01378832)
- Testing
- Intra-peritoneal antibiotic lavage
- Volunteers
- 102 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Smoking Cessation
A Pilot Study Of Smoking Cessation Treatment Including Varenicline In Patients Scheduled For Planned Surgery
It is possible to offer smoking cessation treatment including varenicline to patients scheduled for elective surgery. This study will evaluate whether or not this will enable some patients to quit smoking for up to 4 weeks prior…
- Trial name
- NCT00889720
- Testing
- Varenicline
- Where
- 2 sites in France, Italy
- Volunteers
- 16 people
- Sponsor
- Pfizer
Oral Squamous Cell Carcinoma
Survival Benefit of Elective Neck Dissection in T1,2N0M0 Oral Squamous Cell Carcinoma
Controversy over surgical treatment of clinically negative neck in early stage oral squamous cell carcinoma revolves around the uncertainty of its impact on patient prognosis.
- Trial name
- NCT01334320
- Testing
- elective neck dissection
- Where
- 4 sites in China
- Volunteers
- 448 people
- Sponsor
- Sun Yat-sen University
Supraglottic Cancer
Radiotherapy vs Neck Dissection for Clinical T1/2N0 Supraglottic Cancer
Supraglottic cancer is a main type of laryngeal carcinoma, which is one of the most common head and neck tumors. Cervical nodal metastasis is an important prognostic factor in supraglottic cancer.
- Trial name
- NCT03358602
- Testing
- Radiotherapy, Selective neck dissection
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Anesthesia, General, Neuromuscular Blockade
Comparison of 2.0 mg/kg Sugammadex and Neostigmine at Reappearance of T2 in Chinese and European Subjects (Study 19.4.324)(P05768AM1)(COMPLETED)
The present trial was set up to evaluate the efficacy and safety of 2.0 mg.kg-1 sugammadex compared to neostigmine administered at reappearance of T2 in Chinese and Caucasian subjects for registration purposes in China.
- Trial name
- NCT00825812
- Testing
- Sugammadex, neostigmine
- Volunteers
- 308 people
- Sponsor
- Merck Sharp & Dohme LLC
Osmotherapy, Intracranial Pressure
Comparison of 20% Mannitol and 3% Hypertonic Saline for Cerebral Relaxation During Elective Supratentorial Craniotomies
Mannitol 20% has long been used to treat elevated intracranial hypertension in trauma and intensive care settings. More recent data indicate that hypertonic saline may be as effective or more effective than mannitol for this…
- Trial name
- NCT01745081
- Testing
- 20% mannitol bolus administration, Hypertonic saline 3% bolus administration
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Université de Sherbrooke
Coronary Artery Disease
Photochemical Tissue Passivation Treatment of Saphenous Vein Grafts in CABG
Early feasibility study of the DurVena Photochemical Tissue Passivation (PTP) device for treatment of saphenous vein grafts in participants undergoing elective coronary artery bypass graft (CABG) surgery.
- Trial name
- NCT06150872
- Testing
- DurVena Photochemical Tissue Passivation
- Where
- Uzbekistan
- Volunteers
- 4 people
- Sponsor
- DurVena, Inc.
ERAS
Comparison of Outcome Between (ERACS) Versus Traditional Methods in Elective CS
The study is designed to evaluate the effect of implementing enhanced recovery after surgery (ERAS) protocol during elective cesarean section on patient's outcome measures.
- Trial name
- ERACS (NCT06225557)
- Testing
- ERAS community recommendation, Traditional postoperative care
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Minia University
Granisetron
Role of Granisetron in Preventing Hypotension After Spinal Anesthesia With Levobupivacaine in Rheumatic Patients Undergoing Elective Cesarean Section
Cardiac disease in pregnancy is a high-risk condition and a major cause of maternal mortality and morbidity. Although direct or immediate death due to cardiovascular disease is rare, it is an important indirect cause of maternal…
- Trial name
- NCT05314257
- Testing
- Granisetron Hydrochloride, 0.9% normal saline
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Assiut University
Hyponatremia
Comparison of Ringer Lactate and Isotonic Acetate Solution as Perioperative Maintenance Fluid for Children
In children fluids are supplemented during surgery to provide volume, to maintain blood glucose levels, electrolyte balance and to meet the ongoing fluid losses during surgery.
- Trial name
- NCT02936167
- Testing
- Ringer Lactate, Plasmalyte
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Hand Injuries, Elective Hand Surgery
The Effects of Electronic Cigarettes on the Microcirculation of the Hand
Cigarette smoking is associated with poor wound healing and worse results after hand surgery. Nicotine and cigarette smoke has been shown to affect blood flow in blood vessels in the hand.
- Trial name
- NCT02206737
- Testing
- No nicotine e-cigarette, Low dose nicotine e-cigarette, High dose nicotine e-cigarette
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Pregnancy
Ultrasound for Comparison of Gastric Antral Volume in Pregnants and Non-pregnants
This study evaluates the effectiveness of ultrasound in term pregnant patients posted for elective lower segment cesarean sections and compared them with non pregnant females posted for elective surgeries.
- Trial name
- NCT03380637
- Testing
- ultrasound
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Cicatrix, Scar Prevention
Evaluation of the Safety, Pharmacokinetics, and Preliminary Effect on Scar Formation by RXI-109
The primary purpose of this study is to evaluate the safety and tolerability of a single intradermal administration of RXI-109 at small surgical incisions in the abdominal skin that will later be removed during an elective…
- Trial name
- NCT01640912
- Testing
- RXI-109
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- RXi Pharmaceuticals, Corp.
Coronary Artery Disease
Antithrombotic Regimens and Outcome
PROTOCOL SYNOPSIS Title: Comparison of bivalirudin and unfractioned heparin (UFH)+ protamine in elective percutaneous coronary interventions (PCI) Design: Prospective, randomized, controlled trial Hypothesis: Bivalirudin is…
- Trial name
- ARNO (NCT00448461)
- Testing
- heparin, bivalirudin
- Where
- Italy
- Volunteers
- 850 people
- Sponsor
- Careggi Hospital
Total Hip Arthroplasty (THA)
Impact of Rehabilitation Therapy Using Strength and Blood Flow Restriction Training on Muscular Fitness and Regeneration After Elective Hip Replacement
In the present project, the framework conditions of outpatient rehabilitation at the Bonn Center for Outpatient Rehabilitation will now be used to prove whether sports science-controlled strength and BFR training has a similar…
- Trial name
- NCT07043127
- Testing
- BFR
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bonn
Postoperative Sore Throat, Cough, Hoarseness, Thyroid and Parathyroid Surgery
Sore Throat After Open Neck Elective Surgery
This randomized clinical trial aims to evaluate the effectiveness of two medications-hydrocortisone ointment and lidocaine solution-applied to the endotracheal tube in reducing postoperative throat pain, hoarseness, and cough…
- Trial name
- STONES (NCT07124650)
- Testing
- Hydrocortisone Acetate 1% Ointment, Lidocaine hydrochloride 0,05% with chlorhexidine
- Where
- Russia
- Volunteers
- 764 people
- Sponsor
- Saint Petersburg State University, Russia
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