Clinical trials: Elective
Heart Failure, Hip Fracture
Preoperative Levosimendan and Heart Failure
The purpose of this study is to investigate the safety and efficacy of Levosimendan given preoperative to patients with heart failure undergoing noncardiac surgery.
- Trial name
- PELS (NCT01022983)
- Testing
- Levosimendan
- Where
- 4 sites in Norway, Sweden
- Sponsor
- Sykehuset i Vestfold HF
Coronary Artery Disease
Short-term Outcomes of Elective High-risk PCI With Extracorporeal Membrane Oxygenation Support: a Single-centre Registry
Background Revascularization of complex coronary artery disease, including multivessel coronary artery disease, left main stenosis, bifurcation stenosis and chronic total occlusions (CTO) can be performed by Percutaneous Coronary…
- Trial name
- NCT05387902
- Testing
- Extracorporeal Membrane Oxygenation
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- Robert Jan van Geuns
Post Partum Hemorrhage
Carbetocin in the Prevention of Primary Postpartum Haemorrhage
Postpartum haemorrhage (PPH) ranks as the first cause of maternal mortality in developing countries and it is the cause of 25% of maternal deaths worldwide.
- Trial name
- NCT06159959
- Testing
- Carbetocin
- Where
- Egypt
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Ministry of Health and Population, Egypt
Total Joint Arthroplasty, Risk Reduction
Arthroplasty and Modifiable Risk Factors
Hip and knee total joint arthroplasty are one of the most frequently performed surgery worldwide. However, prosthetic joint infection remains a devastating complication of them, associated with severe morbidity, increased…
- Conditions
- Total Joint Arthroplasty, Risk Reduction, Surgical Site Infection, Prosthetic-joint Infection
- Trial name
- NCT05399186
- Testing
- Early preoperative assessment and optimization
- Where
- Iceland
- Volunteers
- 1,484 people, healthy volunteers welcome
- Sponsor
- Landspitali University Hospital
Difficult Airway Intubation
The VL3 Videolaryngoscope for Elective Tracheal Intubation in Adults
We conducted an observational prospective pilot study to assess the efficacy of the VL3 videolaryngoscope for routinely tracheal intubation in 56 adults, in terms of successful rate, no.
- Trial name
- NCT04252222
- Testing
- Videolaryngoscopy with VL3
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- Campus Bio-Medico University
Diabetes Mellitus, Surgical Procedure, Unspecified
DRIVE - Perioperative Period
This study will investigate if the HbA1c result before surgery which assesses glucose control over the longer term, can accurately predict what happens to the glucose levels and glucose profile following surgery.
- Trial name
- DRIVE-Periop (NCT04033705)
- Testing
- Freestyle Libre Pro glucose sensor
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Inhalation Anesthesia, Dexmedetomidine
The Impact of a Single Dexmedetomidine Bolus on Intraoperative Sevoflurane Consumption (DEXHALE)
Sevoflurane is a volatile agent easy to control thanks to the Minimum Alveolar Concentration (MAC) allowing its titration for an optimal depth of anesthesia.
- Conditions
- Inhalation Anesthesia, Dexmedetomidine, Sevoflurane, Laparoscopy
- Trial name
- NCT05615194
- Testing
- Dexmedetomidine
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Gastric Emptying, Pregnancy
Rate of Gastric Emptying in Term Parturients Undergoing Elective Cesarean Section
The aim of the study is to use sequential ultrasound evaluation of the gastric volume to determine how long it takes for the stomach of a fasting pregnant woman at term, admitted for elective cesarean section, to empty after…
- Trial name
- NCT03800251
- Testing
- Nutricia PreOp - a clear, non-carbonated, lemon flavoured, carbohydrate drink that provides 0.5kcal/ml
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Coombe Women and Infants University Hospital
Smoking, Elective Surgery
Decision Aid Development for Smokers
A decision aid tool will be developed using participatory research approach. The decision aid will be targeted to cigarette smokers scheduled for elective surgery.
- Trial name
- NCT01193972
- Testing
- Decision aid
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Mayo Clinic
Elective Surgery
ED90 of Fospropofol Disodium in Induction and Maintenance of Anesthesia
Exploring the 90% effective dose (ED90) of fospropofol disodium in induction and maintenance of anesthesia in adults of different ages, providing more clinical evidence for the application of fospropofol disodium in clinical…
- Trial name
- NCT06344325
- Testing
- fospropofol
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Tongji Hospital
Surgery, Death
Risk Calculators Validation for Elective Major General Surgery
Nowadays, over 300 million surgical operations take place every year worldwide, which increase at a rate of 33.6% comparing data from 2005 to 2013.
- Trial name
- RCVEMG (NCT04041076)
- Testing
- Major surgical operation
- Where
- Hong Kong
- Volunteers
- 5,000 people
- Sponsor
- Chinese University of Hong Kong
Postoperative Pain Following Hysterectomy
TAP Block With Lidocaine and Ropivacaine 0.2% (0.4 ml/kg/Side) for Pain and Opioid Reduction After Hysterectomy
The goal of this study is to evaluate whether the Transversus Abdominis Plane (TAP) block can effectively reduce postoperative pain and opioid consumption in patients undergoing elective hysterectomy.
- Trial name
- TAP (NCT07139691)
- Testing
- Pre-incisional Transversus Abdominis Plane (TAP) block performed under ultrasound guidance. The block will be administered bilaterally using a mixture of lidocaine and ropivacaine 0.2%, Participants in this arm will receive standard analgesia for postoperative pain management following elective hysterectomy
- Where
- Romania
- Volunteers
- 82 people
- Sponsor
- Matild Keresztes
Inguinal Hernia, Pain, Postoperative
Efficacy of an Anterior Quadratus Lumborum Block vs. a TAP-block for Inguinal Hernia Repair
One of the most common complications after hernia repair is postoperative and chronic pain. TAP (transverse abdominis plain) block is a recommended multimodal method of reducing postoperative pain in laparoscopic and open…
- Trial name
- NCT03023462
- Testing
- Oksykodonhydroklorid, Ondansetron and Droperidol, Ropivacaine
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Ostfold Hospital Trust
Patients Scheduled for Elective Lower Extremity Surgery, Ages 18-80
Parasacral Ischial Plane Block in Lower Extremity Surgery
The parasacral ischial plane block is a novel fascial plane approach targeting the sacral plexus. This technique is technically less challenging and eliminates the requirement for direct visualization of the sacral plexus.
- Conditions
- Patients Scheduled for Elective Lower Extremity Surgery, Ages 18-80, ASA I-III, Patients Operated on Under Regional Anesthesia
- Trial name
- NCT07594197
- Testing
- Parasacral Ischial Plan Block, Sacral plexus block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Aneurysm
Cognition and Functional Connectivity After Elective Treatment of Brain Aneurysms
The aim of this proposal is to investigate the effects of uneventful microsurgical and endovascular treatment of unruptured saccular non-giant anterior communicating artery [ACoA] aneurysms on resting state functional…
- Trial name
- NCT03140020
- Testing
- Clipping, Coiling
- Where
- 2 sites in Austria
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Neck Cancer, Larynx
Bilateral Elective Neck Dissection in Salvage Total Laryngectomy
The aim of this study is to evaluate the role of elective bilateral neck dissection in patients with clinically negative lymph nodes (cN0) who underwent salvage total laryngectomy, by estimating the prevalence of histologically…
- Conditions
- Neck Cancer, Larynx, Larynx Cancer, Neck
- Trial name
- NCT05746780
- Testing
- Elective bilateral neck dissection in cN0 patients
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Frailty, Perioperative/Postoperative Complications
Correlation of Preoperative Global Olfactory Function With Frailty, Perioperative Neurocognitive Disorders and Mortality
The aims of this research project are to evaluate whether global olfactory impairment is a reliable indicator of preoperative frailty and cognitive impairment, and whether it may predict postoperative neurocognitive disorders…
- Conditions
- Frailty, Perioperative/Postoperative Complications, Olfactory Disorder, Neurocognitive Disorders
- Trial name
- NCT04761458
- Testing
- Olfactory function testing, Edmonton Frail Scale, Clinical Frailty Scale
- Where
- Belgium
- Volunteers
- 215 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Cesarean Section, Local Anesthetic
Chloroprocaine 1% Versus Ropivacaine 0,75% During Cesarean Section
This will be a prospective randomized study, aiming at comparing an intrathecal fixed dose of chloroprocaine 1% versus an intrathecal fixed dose of ropivacaine 0.75% in elective cesarean sections
- Trial name
- annie-mariana (NCT06376058)
- Testing
- Chloroprocaine 1% Injectable Solution, Ropivacaine 0.75% Injectable Solution
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Aretaieion University Hospital
Preoperative Care, Telenursing
TELENURSING IN THE IMMEDIATE PREOPERATIVE PERIOD OF ELECTIVE SURGERIES
Introduction: Telenursing encompasses Nursing Consultation, Interconsultation, Consulting, Monitoring, Health Education and Reception of Spontaneous Demand mediated by Information and Communication Technology.
- Conditions
- Preoperative Care, Telenursing, Patient Safety, Elective Surgical Procedures
- Trial name
- TIPPES (NCT07068152)
- Testing
- Preoperative telenursing
- Where
- Brazil
- Volunteers
- 352 people
- Sponsor
- Rio de Janeiro State University
Thrombocytopenia Associated With Chronic Liver Disease
A Study to Evaluate the Safety and Efficacy of PN20 in the Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Undergoing an Elective Procedure
The main aim of this clinical trial is to assess the safety and efficacy of a single dose of PN20 in treatment of thrombocytopenia in adult patients with chronic liver disease undergoing an elective procedure.
- Trial name
- NCT07446491
- Testing
- PN20
- Where
- 8 sites in China
- Volunteers
- 54 people
- Sponsor
- Chongqing Peg-Bio Biopharm Co., Ltd.
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