Clinical trials: Elective Surgery
Mechanical Ventilation, Lung Protective Ventilation
Driving Pressure Guided Mechanical Ventilation Versus Lung Protective Ventilation Among Patients Undergoing Elective Surgeries
Patient undergoing surgeries in general anesthesia require support of their breathing by ventilator. Different strategies can be used to manage breathing of the patient.
- Conditions
- Mechanical Ventilation, Lung Protective Ventilation, Driving Pressure
- Trial name
- NCT07092943
- Testing
- Lung protective ventilation, Driving pressure guided ventilation
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Procedural Anxiety, Coronary Artery Disease
Video-based Intervention to Reduce Anxiety in Patients Undergoing Elective PCI
This study aims to evaluate the effectiveness of a video-based educational intervention in reducing anxiety among hospitalised patients scheduled for elective percutaneous coronary intervention (PCI).
- Conditions
- Procedural Anxiety, Coronary Artery Disease, Percutaneous Coronary Intervention Patients
- Trial name
- NCT07485088
- Testing
- Video intervention
- Where
- Singapore
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Stress
Effects of TEAS on Stress Response During Extubation of General Anesthesia in Elderly Patients
Elderly patients have an increased risk of stress responses during extubation after general anaesthesia for an elective supratentorial craniotomy.
- Trial name
- NCT02533388
- Testing
- Hwato Electronic Acupuncture Treatment Instrument
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Pruritus
Effect of Granisetron on Morphine Induced Pruritus in Cesarean Section
Neuraxial anesthesia, which includes epidural anesthesia and intrathecal anesthesia, is a frequent anesthetic approach for caesarean delivery and other lower abdominal and lower limb anesthetic procedures.
- Trial name
- NCT03483870
- Testing
- Morphine Sulfate, Granisetron
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cesarean Section Complications, Cesarean Wound; Dehiscence
PICO Negative Pressure Wound Therapy in Obese Women Undergoing Elective Cesarean Delivery.
A randomized controlled, parallel group, superiority, open-label, single-institution, Phase 3 interventional clinical trial to evaluate clinical outcomes in obese gravidas undergoing elective cesarean delivery whose wounds were…
- Conditions
- Cesarean Section Complications, Cesarean Wound; Dehiscence, Cesarean Wound Disruption
- Trial name
- NCT03414762
- Testing
- PICO Negative Pressure Wound Therapy, Standard Dressing
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Intubation; Difficult or Failed
Ramped and Sniffing Position for Cesarean Section Intubation.
This study will include pregnants who preferred to undergo general anesthesia for elective cesarean section. Ramped and sniffing positions of pregnant women during ventilation and intubation will be compared.
- Trial name
- NCT06107751
- Testing
- Ramped position group, Sniffing position group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Preoperative Hypothermia
Active Warming During Elective Caesearean Section
During anaesthesia for caesarean section it is common to lose heat and become hypothermic, (<36 degrees C). In order to try and avoid this all women are given warmed intravenous fluid and insulated from cold surfaces.
- Trial name
- NCT02201095
- Testing
- Forced air warming, Conduction warming mattress
- Where
- United Kingdom
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Cerclage, Cervical
ED90 of 3% Chloroprocaine for Cervical Cerclage
The aim of this study is to identify the dose of intrathecal (IT) chloroprocaine that provides effective anesthesia in 90% of patients undergoing elective cerclage placement (intraoperative analgesic supplementation not required).
- Trial name
- NCT03805438
- Testing
- Chloroprocaine Hcl 3% Inj
- Where
- 2 sites in United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Duke University
Wound Infection
Catheterization During Second Elective Caesarean Delivery
Use versus non use of urinary catheterization during Second Elective caesarean delivery:
- Trial name
- CDSECD (NCT02143089)
- Testing
- Foley's Catheter
- Where
- Egypt
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anesthesia, Anxiety
Media Use, Anxiety, Sedation, and Recovery in Children Having Upper GI Endoscopy
This observational study will investigate whether problematic digital media use is associated with anxiety in children undergoing a planned upper gastrointestinal endoscopy, a camera examination of the upper digestive tract.
- Trial name
- PMU-ASR-ENDO (NCT07916168)
- Testing
- Problematic Media Use
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Laryngeal Masks Comparison
Respiration and The Airway With Supraglottic Airway Devices
The investigators aim to compare the airway seal pressure( oropharyngeal leak pressure) of the Self Pressurized Airway Device with Blocker® with the ProsealTM Laryngeal Mask Airway (P-LMA)in anesthetized paralyzed adult female…
- Trial name
- NCT03384056
- Testing
- Self Pressurized Airway Device with Blocker, Proseal Laryngeal Mask Airway
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Reham Ali Abdelhaleem Abdelrahman
Catheter Related Bladder Discomfort
Efficacy of Hyoscine-n-butylbromide in Catheter-related Bladder Discomfort After Elective Cesarean Section.
a prospective, randomized, placebo-controlled study will be conducted to investigate whether hyoscine-n-butylbromide has preventive effects on early postoperative CRBD in patients with urinary catheters who will undergo elective…
- Trial name
- NCT03513250
- Testing
- hyoscine-n-butylbromide, control group
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Cairo University
Total Joint Arthroplasty, Risk Reduction
Arthroplasty and Modifiable Risk Factors
Hip and knee total joint arthroplasty are one of the most frequently performed surgery worldwide. However, prosthetic joint infection remains a devastating complication of them, associated with severe morbidity, increased…
- Conditions
- Total Joint Arthroplasty, Risk Reduction, Surgical Site Infection, Prosthetic-joint Infection
- Trial name
- NCT05399186
- Testing
- Early preoperative assessment and optimization
- Where
- Iceland
- Volunteers
- 1,484 people, healthy volunteers welcome
- Sponsor
- Landspitali University Hospital
Postoperative Period
Fast-track Discharge After Elective Cesarean Section
Cesarean section (CS) is a procedure with prolonged hospital stay compared to the routine for normal vaginal delivery in multiparas.
- Trial name
- NCT02911727
- Testing
- Fast-track discharge
- Where
- Denmark
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Herning Hospital
Postoperative Pain, Cesarean Section
Liposomal Bupivacaine + Bupivacaine vs. Bupivacaine Alone on Opioid Use After Elective c/Section
The purpose of this study is to compare the effectiveness of local wound infiltration of EXPAREL® (liposomal bupivacaine) with bupivacaine HCl compared to active control with bupivacaine HCl alone following elective primary or…
- Trial name
- NCT04232306
- Testing
- Liposomal bupivacaine, Bupivacaine HCl
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Abortion, Therapeutic
A Randomized Study of Cervical Priming With Misoprostol Prior to Elective First Trimester Pregnancy Termination
The purpose of this study is to determine whether misoprostol administered prior to elective first trimester pregnancy has an effect on pain and ease of procedure and complications.
- Trial name
- NCT00310921
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Morbid Obesity
The Ultrasound Guided Versus Land-mark Location Method for Performing Spinal Anesthesia in Obese Parturients
This study will be investigated whether an ultrasound-assisted technique is better than a classical land-mark technique to facilitate spinal anesthesia in the lateral position in morbidly obese pregnant women with BMI ≥ 40 who…
- Trial name
- NCT05342922
- Testing
- Ultrasound group, Landmark group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Scar Prevention
Safety and Efficacy Study of Different Dose Levels of EXC 001 to Improve the Appearance of Scars in Subjects Undergoing Elective Abdominoplasty
This study will compare how well EXC 001 works versus placebo in reducing the appearance of scars in subjects undergoing elective abdominoplasty. The study will also evaluate the safety of EXC 001 in healthy adult subjects.
- Trial name
- NCT01038297
- Testing
- EXC 001
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pfizer
Opioid Use
Pregabalin Versus Gabapentin Opioid Sparing Effect in Discectomy
Pregabalin and gabapentin are both GABA analogue and their mechanism of action is not fully understood. Both drugs when given as a pre-emptive analgesia for spinal surgery were found to reduce intra-and postoperative opioid…
- Trial name
- NCT05539924
- Testing
- Pregabalin 150mg gabapentin 400mg
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Research Institute of Ophthalmology, Egypt
Postpartum Hemorrhage
Oxytocin i.m./i.v. Versus Carbetocin i.v. in Elective Cesarean Sections
Objective is to proof non-inferiority of intramyometrial and intravenous oxytocin application compared to intravenous carbetocin for prevention of postpartum hemorrhage in planned, uncomplicated cesarean deliveries.
- Trial name
- NCT03651882
- Testing
- Oxytocin, Carbetocin
- Where
- Switzerland
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- University of Zurich