Clinical trials: Electric Countershock
Cardiac Arrest, Heart Arrest
ICD Shock Detection by a Wearable
Trial to assess the ability of a wearable to detect defibrillation from an implantable ICD
- Conditions
- Cardiac Arrest, Heart Arrest, Cardiopulmonary Arrest
- Trial name
- LOISICD (NCT04565652)
- Testing
- Device Wearers
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Lois Medical LTD
Arrythmia, Implatable Cardioverter Defibrillation, Lead
Safety and Electrical Performances Evaluation of Navigo Leads Equipped With IS4 Connector
The primary objective of this study is to assess the safety and electrical performance of Left ventricular (LV) NAVIGO 4LV leads, pre-shaped (S-shaped\&U-shaped: NAVIGO 4LV 2D, NAVIGO 4LV ARC) and Straight (NAVIGO 4LV PILOT)…
- Trial name
- NAVIGATOR (NCT03279484)
- Testing
- NAVIGO 4LV lead implant
- Where
- 38 sites in France, Germany and 4 more
- Volunteers
- 317 people
- Sponsor
- MicroPort CRM
Heart Failure, Heart Failure With Reduced Ejection Fraction
Assessment of Combined CCM and ICD Device in HFrEF
The goal of this clinical trial is to demonstrate that the OPTIMIZER® Integra CCM-D System (the "CCM-D System") can safely and effective convert induced ventricular fibrillation (VF) and spontaneous ventricular tachycardia and/or…
- Conditions
- Heart Failure, Heart Failure With Reduced Ejection Fraction, Implantable Defibrillator User, CCM Therapy
- Trial name
- INTEGRA-D (NCT05855135)
- Testing
- OPTIMIZER® Integra CCM-D System (Treatment Arm)
- Where
- 59 sites in United States
- Volunteers
- 300 people
- Sponsor
- Impulse Dynamics
Tachycardia
Acute Defibrillation Performance of a Novel Can-less Shock Pathway
Evaluate the operation of the Implantable Subcutaneous String Defibrillator (ISSD) system in patients who require an Implantable Cardioverter Defibrillator (ICD) using an emulator.
- Trial name
- NPC01PRG (NCT02941250)
- Testing
- ISSD emulator
- Where
- Czechia
- Volunteers
- 22 people
- Sponsor
- NewPace Ltd
Atrial Fibrillation
Ranolazine for the Prevention of Atrial Fibrillation After Electrical Cardioversion
The investigators hypothesize that ranolazine would decrease the incidence of recurrence of Atrial Fibrillation (AF) after electrical cardioversion of persistent AF.
- Trial name
- GILEAD (NCT01349491)
- Testing
- Ranolazine
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Oklahoma
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Efficacy and Safety Evaluation of Refralon®, Concentrate for Solution for Intravenous Injection in Patients With Paroxysmal and Persistent Atrial Fibrillation and Flutter
The goal of this retrospective registry is to evaluate the efficacy and safety of Refralon®, concentrate for solution for intravenous injection, as chemical cardioversion in patients with paroxysmal and persistent atrial…
- Conditions
- Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation, Atrial Flutter
- Trial name
- NCT05773170
- Testing
- Refralon
- Where
- 33 sites in Russia
- Volunteers
- 1,147 people
- Sponsor
- R-Pharm
Sudden Cardiac Death
Comparison of 50% Tilt and Tuned Waveforms in Single-Coil Active Can Configuration
The purpose of this study is to compare the defibrillation efficacy between the 50/50% tilt biphasic waveform and the Tuned biphasic waveform in a single coil active can configuration.
- Trial name
- PROMISE (NCT00874445)
- Testing
- ICD/ CRT-D
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Devices
Ventricular Tachycardia, Ventricular Fibrillation
Septal - Success Rate and Clinical Outcome of Septal Implant of Ventricular Defibrillation Lead
The purpose of this study is to determine the safety and efficacy of the implant of a ICD lead of defibrillation in the septum of the right ventricle
- Trial name
- NCT00180297
- Testing
- Endotak Reliance G
- Where
- 18 sites in France
- Volunteers
- 215 people
- Sponsor
- Boston Scientific Corporation
Erectile Dysfunction
Evaluation for Restoration of Erectile Dysfunction After Cardioversion Treatment Trial
Erectile and Cognitive function by using the questionnaire and assessment form before sinus conversion
- Trial name
- NCT02742896
- Testing
- Erectile dysfunction
- Where
- South Korea
- Sponsor
- Yong Seog Oh
ICD
Myocardial Injury in Patients With Cardiac Implantable Electronic Devices Undergoing Defibrillation Threshold Testing
Researchers are trying to determine if heart injury occurs in patients with a cardiac implantable electronic device (CIED) who undergo a defibrillation threshold testing (DFT) procedure.
- Trial name
- NCT04284800
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Mayo Clinic
Atrial Fibrillation
Stepwise Strategy for Treatment of Atrialfibrillation Substrate Study
Electrical/pharmacological cardioversion improves structural remodeling of left atrium. We hypothesized that radiofrequency ablation surgery for atrial fibrillation has a higher success rate and a lower recurrence rate of atrial…
- Trial name
- SAFE (NCT07129564)
- Testing
- treatment react
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Yuehui Yin
Out-of-hospital Cardiac Arrest (OHCA)
Potassium Chloride in Out-of-hospital Cardiac Arrest Due to Refractory Ventricular Fibrillation
The purpose of this study is to evaluate, in patients presenting with out-of-hospital cardiac arrest (OHCA) by ventricular fibrillation, refractory to 3 external electric shocks, the efficacy of a direct intravenous injection of…
- Trial name
- POTACREH (NCT04316611)
- Testing
- Potassium chloride
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Atrial Fibrillation
Assessment of Thrombotic Status in Patients With Atrial Fibrillation
Investigators will assess the impact of treatments for atrial fibrillation on participant's thrombotic status
- Trial name
- NCT02583971
- Volunteers
- 500 people
- Sponsor
- East and North Hertfordshire NHS Trust
Defibrillator, Tricuspid Valve Regurgitation
Early Feasibility Study of 3930M Defibrillation Lead Implantation Via the Middle Cardiac Vein in Patients With Tricuspid Valve Regurgitation
Prospective, single center, early feasibility study designed to evaluate the initial safety and device performance of the Medtronic 3930M Lead when implanted via the Middle Cardiac Vein in patients with Tricuspid Valve…
- Trial name
- MCV3930 EFS (NCT07811609)
- Testing
- Defibrillator
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Minneapolis Heart Institute Foundation
Atrial Fibrillation
Time-dependent Amiodarone Treatment in Atrial Fibrillation
Sixty consecutive emergency patients with newly diagnosed Atrial Fibrillation were randomized into two groups. The first received intravenous amiodarone infusions continuously for 24 hours; the second received Amiodarone until…
- Trial name
- NCT03432663
- Testing
- Intravenous amiodarone(1), Intravenous amiodarone(2)
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto de Cardiología y Medicina Vascular Hospital Zambrano-Hellion Tec Salud
Atrial Fibrillation, Defibrillators
Double Sequential External Defibrillation in Patients With Atrial Fibrillation Refractory to DC Cardioversion
Atrial fibrillation (AF) is a common cardiac arrhythmia that leads to increased risk of heart failure, hospitalization, thromboembolic events, and death.
- Conditions
- Atrial Fibrillation, Defibrillators, Persistent Atrial Fibrillation
- Trial name
- NCT03827915
- Testing
- Double sequential external defibrillation
- Where
- Lebanon
- Volunteers
- 100 people
- Sponsor
- American University of Beirut Medical Center
Persistent Atrial Fibrillation
Atrial Fibrillation Trial to Evade Recurrence: effectS of Hiit Before electrO-Cardioversion for 3-weeKs
This is a study looking at the feasibility of conducting a larger definitive research trial looking at the effectiveness of high intensity interval training in individuals who are scheduled for electro-cardioversion.
- Trial name
- AFTERSHOCK (NCT03467633)
- Testing
- High-intensity interval training
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Atrial Fibrillation
A Study Evaluating the Efficacy and Safety of AP30663 for Cardioversion in Participants With Atrial Fibrillation (AF)
This study will evaluate the efficacy, safety, tolerability and pharmacokinetics (PK) of one or more doses of AP30663 for cardioversion in adult participants with AF.
- Trial name
- NCT04571385
- Testing
- AP30663
- Where
- 15 sites in Denmark, Hungary
- Volunteers
- 66 people
- Sponsor
- Acesion Pharma
Defibrillation Capacity of Defibrilators After Replacement
Cardioverter Defibrillator Replacement With Induction of Ventricular Fibrillation and Defibrillation Testing
The SIMPLE study was a large one, and lasted quite a few years due to its design as a randomized controlled trial and the follow up needed to reach an endpoint.
- Trial name
- SIMPLER (NCT02513030)
- Testing
- Defibrillation testing during ICD replacement
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Atrial Fibrillation (AF), Atrial Flutter
Left Atrial Imaging Prior to Cardioversion: Leveraging Computed Tomography to Rule Out Thrombus in The Emergency Department (LA CLOTTED)
The goal of this randomized clinical trial is to learn whether patients with symptomatic atrial fibrillation or atrial flutter (AF) who require heart imaging to rule out a blood clot before cardioversion would benefit from…
- Trial name
- LA CLOTTED (NCT07002450)
- Testing
- Cardiac computed tomography angiography, Standard of care management
- Where
- 3 sites in United States, Canada
- Volunteers
- 190 people
- Sponsor
- Ottawa Heart Institute Research Corporation