Clinical trials: Embolism, Pulmonary
Pulmonary Embolism, Pulmonary Thromboembolism
The PERSEVERE Study
Randomized Controlled Trial of High-Risk Pulmonary Embolism Comparing FlowTriever System vs. Standard of Care
- Trial name
- NCT06588634
- Testing
- FlowTriever System, Standard of Care
- Where
- 33 sites in United States, France and 4 more
- Volunteers
- 200 people
- Sponsor
- Inari Medical
Acute Myocardial Infarction, Heart Failure
SHORTness of Breath In the Emergency Department (SHORTIE)
SHORTIE is a two-phase study to determine the impact of the Triage Profiler S.O.B. (Shortness Of Breath) Panel on patient management, outcome, and cost.
- Conditions
- Acute Myocardial Infarction, Heart Failure, Pulmonary Embolism
- Trial name
- NCT00206830
- Testing
- Triage Profiler S.O.B. Panel
- Where
- 5 sites in United States
- Volunteers
- 306 people
- Sponsor
- Abbott RDx Cardiometabolic
Venous Thromboembolism
DULCIS (D-dimer and ULtrasonography in Combination Italian Study)
The purpose of this study is to evaluate the efficacy and safety of a standardized procedure to establish the optimal duration of anticoagulation in patients with venous thromboembolism.
- Trial name
- DULCIS (NCT00954395)
- Testing
- D-dimer
- Where
- Italy
- Volunteers
- 1,100 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
COVID-19
In Situ Thrombolysis With tPA and Inflow Perfusion Analysis in Patient With Severe Covid-19 Infection
To estimate the pulmonary response microvascular thrombosis in critical patients due to SARS-Cov-2., at the Hospital General de México "Dr.
- Trial name
- NCT04926428
- Testing
- tPA
- Where
- Mexico
- Volunteers
- 15 people
- Sponsor
- Grupo Mexicano para el Estudio de la Medicina Intensiva
Pulmonary Embolism
High-Flow Nasal Cannula Versus Non-Invasive Ventilation for Acute Respiratory Failure in Pulmonary Embolism.
Acute pulmonary embolism (PE) often causes hypoxemic respiratory failure through ventilation-perfusion mismatch and right-ventricular (RV) strain; supportive oxygenation plus prompt anticoagulation are crucial to care .
- Trial name
- NCT07381712
- Testing
- High-Flow Nasal Cannula (HFNC), Non-Invasive Ventilation (NIV)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Venous Thromboembolic Disease, Pulmonary Embolism
CHIPs-VTE Study in Hospitalized Patients to Prevent Hospital-Acquired Venous Thromboembolism
Although pharmacologic and mechanical methods to prevent VTE are safe, effective, cost-effective, and advocated by authoritative guidelines,many studies continue to demonstrate that these preventive methods are significantly…
- Conditions
- Venous Thromboembolic Disease, Pulmonary Embolism, Venous Thromboembolism, Deep Venous Thrombosis
- Trial name
- NCT04211181
- Testing
- The multifaceted interventions, Routine VTE prophylaxis
- Where
- China
- Volunteers
- 5,800 people
- Sponsor
- China-Japan Friendship Hospital
Venous Thrombosis, Pulmonary Embolism
Study of Apixaban for the Prevention of Thrombosis-related Events in Patients With Acute Medical Illness
The purpose of this study is to learn if apixaban can prevent blood clots in the leg (deep vein thrombosis [DVT]) and lung (pulmonary embolism [PE]) that sometimes occur within patients hospitalized for acute medical illness, and…
- Trial name
- ADOPT (NCT00457002)
- Testing
- Apixaban, Enoxaparin
- Where
- 296 sites in United States, Argentina and 33 more
- Volunteers
- 6,758 people
- Sponsor
- Bristol-Myers Squibb
Pulmonary Hypertension, Pulmonary Embolism (Diagnosis)
China Pulmonary Vascular Disease Intervention Diagnosis and Management Study-right Heart Catheterization
Right heart catheterization(RHC) plays a crucial role in the diagnosis and treatment of pulmonary vascular diseases(PVD). In China, the lack of equipment and technical expertise has historically limited the implementation of RHC…
- Conditions
- Pulmonary Hypertension, Pulmonary Embolism (Diagnosis), Pulmonary Arterial Hypertension, Right Heart Catheterization
- Trial name
- CHA-RHC (NCT06954727)
- Testing
- No intervention; Observational study
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- China-Japan Friendship Hospital
Pulmonary Hypertension, Pulmonary Thromboembolisms
Electrical Impedance Tomography for Assessment of Pulmonary Hypertension
Pulmonary hypertension is a serious and progressive disease that is difficult to treat and diagnose, mainly because its symptoms are nonspecific and often delay recognition. Early diagnosis is a major challenge.
- Trial name
- NCT07453017
- Testing
- Electrical Impedance Tomography (EIT), Right Heart Catheterization
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo General Hospital
Pulmonary Embolism With Fever
Pulmonary Embolism and PCT. PE-PCT Study
The clinical manifestations of pulmonary embolism vary greatly from the absence of specific clinical symptoms to cardiogenic shock or cardiac arrest.
- Trial name
- NCT02261610
- Testing
- Procalcitonin algorithm
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Clermont-Ferrand
Deep Venous Thrombosis, Pulmonary Embolism
STA®-Liatest®D-Di-Exclusion of Venous Thromboembolism
The purpose of this study is to demonstrate the ability of STA® Liatest® D-Di combined with a clinical pretest probability (PTP) to safely exclude pulmonary embolism (PE) or Deep Venous Thrombosis (DVT) in a 3 month follow-up.
- Conditions
- Deep Venous Thrombosis, Pulmonary Embolism, D-dimer
- Trial name
- DiET (NCT01221805)
- Where
- 18 sites in United States, Canada and 3 more
- Volunteers
- 2,040 people
- Sponsor
- Diagnostica Stago
Venous Thromboembolism, Deep Venous Thrombosis
The Protrieve PROTECTOR Study
The Protrieve PROTECTOR Study is a prospective, single-arm, multicenter study of the Protrieve Sheath.
- Trial name
- PROTECTOR (NCT06495996)
- Testing
- Percutaneous mechanical thrombectomy (PMT)
- Where
- 15 sites in United States
- Volunteers
- 66 people
- Sponsor
- Inari Medical
Thromboembolism, Venous Thromboembolism
Institutional Registry of Thromboembolic Disease
The purpose of this study is to create an institutional registry of Thromboembolic disease through a prospective survey based on epidemiological data, risk factors, diagnosis, prognosis, treatment, monitoring and survival.
- Conditions
- Thromboembolism, Venous Thromboembolism, Pulmonary Embolism
- Trial name
- IRTD (NCT01372514)
- Where
- Argentina
- Volunteers
- 4,500 people
- Sponsor
- Hospital Italiano de Buenos Aires
COVID-19 Disease, Thromboembolism, Venous
Increased Risk of VTE and Higher Hypercoagulability in Patients Recovered in ICU and in Medical Ward for COVID-19
The aim of this study is to verify if patients admitted to hospital in a medical division and in the intensive care unit for a COVID-19 infection are at higher risk of developing a VTE complication and if they actually present an…
- Trial name
- VTE-COVID (NCT04359212)
- Testing
- thromboprophylaxis with low-molecular-weight heparin or fondaparinux
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Quovadis Associazione
Pulmonary Embolism
Evaluation of the PERC Score and the YEARS Algorithm in the Diagnosis of Pulmonary Embolism in the Emergency Department
The current diagnostic strategy for pulmonary embolism relies on clinical evaluation, followed by D-dimer testing and chest CT angiography. However, this approach leads to overuse of CT angiography.
- Trial name
- EP (NCT07313501)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Pulmonary Embolism (Diagnosis), Venous Thromboembolism (VTE)
3D-EIT for Diagnosis and Monitoring of Pulmonary Embolism
This prospective observational study aims to validate three-dimensional electrical impedance tomography (3D-EIT) as a non-invasive bedside tool for the diagnosis and longitudinal monitoring of pulmonary embolism (PE).
- Trial name
- TIDE-PE (NCT07560293)
- Volunteers
- 115 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Pulmonary Thromboembolisms, Pulmonary Embolism
Non-Contrast 4DCT to Detect Pulmonary Thromboembolic Events
Deep vein thrombosis (DVT) occurs when a blood clot forms in a deep vein, typically in the lower extremities. Pulmonary embolism (PE) occurs when a DVT clot (or fragment) breaks free and travels through the heart to the pulmonary…
- Trial name
- NCT03183063
- Testing
- 4DCT and SPECT/CT, 4DCT with BiPAP and SPECT/CT, 4DCT with CTA in suspected PE
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Thomas Guerrero
Pulmonary Embolism, Venous Thromboembolism
Prognostic Value of 2026 AHA/ACC Clinical Categorization in Acute Pulmonary Embolism Patients Presenting to the Emergency Department
Background: The 2026 American Heart Association/American College of Cardiology (AHA/ACC) Pulmonary Embolism Guideline (Creager et al., Circulation 2026) introduced a novel five-category (A-E) clinical classification system with…
- Conditions
- Pulmonary Embolism, Venous Thromboembolism, Acute Pulmonary Embolism
- Trial name
- APEX-2026 (NCT07805616)
- Testing
- 2026 AHA/ACC Clinical Risk Categorization
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Deep Vein Thrombosis, Pulmonary Embolism and Thrombosis
Apixaban in Thrombocytopenia
This study is being done to determine the feasibility and safety of using a novel dose adjusted apixaban for the management of participants with cancer-associated venous thromboembolism (blood clot) or and thrombocytopenia (low…
- Conditions
- Deep Vein Thrombosis, Pulmonary Embolism and Thrombosis, Thrombocytopenia, Recurrent Venous Thromboembolism
- Trial name
- NCT06886516
- Testing
- Apixaban
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Rushad Patell
Intimate Partner Violence, Deep Vein Thrombosis (DVT)/Thrombophlebitis
Prevalence and Characteristics of Intimate Partner Violence Against Individuals Seeking Hematological Consultations
Intimate violence against individuals, which is particularly marked among women, is one of the most widespread human rights violations in the world.
- Conditions
- Intimate Partner Violence, Deep Vein Thrombosis (DVT)/Thrombophlebitis, Pulmonary Embolism and Thrombosis
- Trial name
- HEMATO-WAST (NCT06415968)
- Where
- France
- Volunteers
- 138 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes