Clinical trials: Emergencies
HIV
ED2PrEP - Patient Focused, Low-burden Strategies for PrEP Uptake Among Emergency Departments
Severe inequities in HIV pre-exposure prophylaxis (PrEP) access and use in communities hardest hit by the HIV epidemic persist, further exacerbating ongoing racial/ethnic and socioeconomic disparities in HIV incidence.
- Trial name
- ED2PrEP (NCT05588193)
- Testing
- PVO, TSH
- Where
- 2 sites in United States
- Volunteers
- 1,560 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Contraception
Etonogestrel Implant as Emergency Contraception
The investigators propose a single site, single arm, open label mechanism of action pharmacodynamic pilot study of etonogestrel implant insertion prior to an luteinizing hormone (LH) surge.
- Trial name
- NCT05237141
- Testing
- Etonogestrel implant
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pulmonary Aspiration, Emergency Surgery
Aspiration Risk Assessment by Gastric Ultrasound in eMErgency Surgery and ANesThetic Decision-making: The ARGUMENT Study
Pulmonary aspiration of gastric contents is a serious patient safety problem accounting for 50% of anesthesia-related mortality.
- Trial name
- NCT06303492
- Testing
- GUS
- Where
- Canada
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Virtual Reality Simulation, Simulation-based Medical Education
Immersive Virtual Reality Simulation-Effects of Self-Guided Versus Facilitator-Guided Debriefing
The goal of this clinical trial is to find out whether self-guided and facilitator-guided virtual reality (VR) simulations are equally effective in helping medical students learn how to manage and treat critically ill children.
- Conditions
- Virtual Reality Simulation, Simulation-based Medical Education, Pediatric Emergency Medicine, Immersive Virtual Reality
- Trial name
- NCT06956833
- Testing
- Ìmmersive virtual reality simulation with self-guided debriefing, Ìmmersive virtual reality simulation with facilitator-guided debriefing
- Where
- Denmark
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pneumonia
Pilot Deployment of ePNa Into Epic EHR
Intermountain Health has developed a electronic decision support tool to help doctors provide the best care for pneumonia. The purpose of this study is to enhance the existing tool (called ePneumonia (electronic Pneumonia) or…
- Trial name
- ePNa-Epic (NCT06008314)
- Testing
- ePNa
- Volunteers
- 6,917 people, healthy volunteers welcome
- Sponsor
- Nathan Dean
Delirium
Haloperidol Prophylaxis in Older Emergency Department Patients
The investigators propose a multicenter, randomized, double-blinded, placebo-controlled trial to study the effect of additive low-dose haloperidol prophylaxis on top of exciting care in a general population of older patients (age…
- Trial name
- HARPOON (NCT01530308)
- Testing
- Haloperidol
- Where
- 6 sites in Netherlands
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Kidney Injury
I USE LR in the ED
To study the difference in mortality and major adverse kidney events during and after treatment in the emergency department with intravenous fluids per standard of care at 30 days before and after the system-wide implementation.
- Trial name
- NCT03807648
- Testing
- Data Inclusion
- Where
- United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Intermountain Health Care, Inc.
Emergencies
How Can Volunteers in the NHS Be Best Supported?
This study aims to investigate the impact of volunteers in the English National Health Service (NHS) and increase the evidence base for supporting and developing volunteering to best help patients and services.
- Trial name
- NCT06678815
- Testing
- Emergency response
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King's College London
Ultrasound, Children
The Rate of Full and Empty Stomach in Elective and Emergency Pediatric Patients
Background and Aim: Pulmonary aspiration of gastric content in the perioperative period is rare, but it is an important cause of morbidity and mortality that anesthetists never want to encounter.
- Conditions
- Ultrasound, Children, Surgery
- Trial name
- NCT04831593
- Testing
- Group El, Group Em
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Ankara Children's Health and Diseases Hematology and Oncology Training and Research Hospital
Medical Education
Analysis of the Effect of Pre-course Videos on Improving Clinical Skills in Emergency Ultrasound Training
Project Background Point-of-Care Ultrasound (POCUS) has become an important part of medical education in recent years. However, due to limited resources of ultrasound machines and clinical instructors, hands-on practice…
- Trial name
- CVC (NCT06947733)
- Testing
- pre-class videos, no pre-class videos
- Where
- Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Appendicitis
Polymer Clips Versus Endoloops for Closure of the Appendiceal Stump During Emergency Laparoscopic Appendicectomy
The investigators propose a study to compare two methods of closing the stump of the appendix during an emergency excision of the appendix using a keyhole approach.
- Trial name
- PECAS (NCT02726152)
- Testing
- Polymer clips for closure of the appendiceal stump, Endoloops for closure of the appendiceal stump
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Health Service, United Kingdom
Anti-Bacterial Agents, Respiratory Tract Infections
Improving Antimicrobial-Prescribing in Emergency Departments
Antimicrobial resistance is one of today's most urgent public health problems. One of the most important strategies to slow the spread of antimicrobial resistance is the promotion of judicious antimicrobial use.
- Trial name
- NCT03349567
- Testing
- Audit-and-feedback
- Where
- 2 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Iowa City Veterans Affairs Medical Center
Elbow Pain, Supracondylar Humerus Fracture
The Utilization of Ultrasound to Diagnose Pediatric Elbow Fractures
The goal of this intervention trial is to learn if a ultrasound diagnosis of elbow fractures can improve care in pediatric patients seen in the emergency room.
- Conditions
- Elbow Pain, Supracondylar Humerus Fracture, Radial Head Fractures, Radial Head or Neck Fractures
- Trial name
- NCT07212036
- Testing
- Ultrasound of the elbow, X-ray of elbow
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Emotional Problem
How Dose Election Event Will Induce Emotion Change of Emergency Room and Critical Unit
In response to the emergence of injuries and illnesses, the manpower of the acute and critical medical team has the requirements. The election keen is rare to see in recent years.
- Trial name
- NCT04371263
- Testing
- Emotional Change of Nursing Manpower in Emergency and Critical Unit After Keen Election And What's The Influence of Emotional Change
- Where
- Taiwan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- St. Martin De Porress Hospital
Pain, Renal Colic
Comparison of IV 10, 20, and 30mg for Renal Colic Pain in the ED
Hypothesis: Intravenous administration of Ketorolac 10 mg and 20 mg is as effective as 30 mg in treating renal colic pain in patients presenting to the emergency department
- Trial name
- NCT03665753
- Testing
- Ketorolac
- Where
- Iran
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Appointments and Schedules, Outpatient Clinics, Hospital/Economics
Non Attendance at Scheduled Appointments as a Marker of Mortality and Hospital Admission
To evaluate the association of non attendance at scheduled appointments with visits in the emergency department, hospitalizations and mortality during one year follow up.
- Conditions
- Appointments and Schedules, Outpatient Clinics, Hospital/Economics, Emergency Department, Hospitalization
- Trial name
- NCT02210637
- Where
- Argentina
- Volunteers
- 177,083 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Nosocomial Infections
ED Residents MBP During CVC Placement: Sim Lab Based Training
1. Baseline performance in maximal barrier precaution technique of Emergency Medicine (EM) residents, certified in CVC placement, is poor 2.
- Trial name
- EM CVC MBP (NCT00791583)
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Pulmonary Embolism Acute
SCUBE-1 and VAP-1 Levels on Diagnosis Pulmonary Embolism
Acute pulmonary thromboembolism is a life-threatening disease. Clinical suspicion is essential for diagnosis because of lack of a specific finding for diagnosis of PTE.
- Trial name
- NCT06733961
- Testing
- SCUBE-1 and VAP-1
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Giresun University
Cesarean Section Complications
Clean-CS: A Program to Improve the Safety of C-section
Executive summary: Cesarean delivery, or section (CS), is the single most common surgical procedure performed. Estimates indicate that in low resource settings, CS comprises up to 50% of more of the total volume of operations…
- Trial name
- Clean-CS (NCT04812522)
- Testing
- Clean Cut program
- Where
- 10 sites in Ethiopia
- Volunteers
- 10,506 people, healthy volunteers welcome
- Sponsor
- The Lifebox Foundation
Night Work
Apples in Night Shift
Background: Emergency doctors face a highly stressful work environment during night shifts. Long-term night shift work can lead to sleep deprivation, fatigue accumulation, and disruption of the biological clock, which may affect…
- Trial name
- NCT06714422
- Testing
- apple group, no apple group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital