Clinical trials: Emergencies
Colorectal Cancer, Wound Infection
Comparing PP and PVDF Meshes in Midline Laparotomy Closure for High-risk Colorectal Surgery. Impact on Incisional Hernia and Surgical Wound Infection.
In the latest guidelines for abdominal wall closure in emergency surgery published in the World Journal of Emergency Surgery (WJES) in 2023, no specific recommendations are made in this regard.
- Conditions
- Colorectal Cancer, Wound Infection, Hernia Incisional
- Trial name
- PROFIMESH (NCT06220045)
- Testing
- Polyvinylidene fluoride mesh, Prophylactic polypropylene mesh
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Anxiety Fear, Pain
Efficacy of Mindfulness as an Intervention in the Pediatric Emergency Department
Non-pharmacological interventions including distraction techniques (ie., games, ipads, bubbles, stickers) are standard of care in reducing situation anxiety for children in the pediatric emergency department.
- Trial name
- NCT03690531
- Testing
- Take-Pause virtual reality, Passive Distraction
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Antonios Likourezos
Heart Arrest, Cardiac Arrest
Pre-arrival Instructions Effect on Bystander Cardiopulmonary Resuscitation (CPR).
The investigators hypothesized that pre-arrival instructions would increase the likelihood of bystanders performing Cardiopulmonary Resuscitation (CPR).
- Conditions
- Heart Arrest, Cardiac Arrest, Cardiopulmonary Arrest, Out of Hospital Cardiac Arrest
- Trial name
- NCT02007499
- Testing
- Pre-Arrival Instructions
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- Medical College of Wisconsin
Post-Concussion Symptoms, Post-Traumatic Stress Disorder
Eye-Movement Desensitization and Post-Traumatic Syndroms
Millions people, all over the world, are admitted in the Emergency Department after a trauma or simply to receive medical cares. In France, it represents 10 million patients.
- Trial name
- SOFTER3 (NCT03400813)
- Testing
- R-TEP EMDR
- Where
- 2 sites in France
- Volunteers
- 314 people
- Sponsor
- University Hospital, Bordeaux
Emergency Patient Transported by Ambulance
Evaluation of Effectiveness for Connected Network for EMS Comprehensive Technical-support Using Artificial Intelligence (CONNECT-AI) System by Community Intervention
This study aims to verify the effectiveness of the connected network for EMS comprehensive technical-support using artificial intelligence (CONNECT-AI) system through demonstration in the local community.
- Trial name
- NCT04829279
- Testing
- CONNECT AI system group
- Where
- South Korea
- Volunteers
- 15,392 people
- Sponsor
- Yonsei University
Sickle-Cell Disease with Crisis
Analgesic Effect of Parecoxib Versus Morphine in SCD Patients Presenting to the Emergency Department
Introduction: This study focuses on the treatment of painful crises in Sickle Cell Disease (SCD) patients using Paracoxib, a non-opioid, compared to Morphine.
- Trial name
- PASC (NCT06315920)
- Testing
- Parecoxib, Morphine
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Oman Medical Speciality Board
Education, Obstetrics
'In Situ Simulation' Versus 'Off Site Simulation' in Obstetric Emergencies
Care for pregnant is a field where unexpected emergencies occur, however emergencies are rare and hence competences difficult to learn. Therefore, it can be relevant to use simulation-based medical education.
- Conditions
- Education, Obstetrics, Simulation, 'In Situ Simulation'
- Trial name
- NCT01792674
- Testing
- In situ simulation, Off site simulation
- Where
- Denmark
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Ventilation
Bag-Valve-Guedel Adaptor Vs Common Face Mask for the Ventilation of Anesthetized Bearded Men
Ventilation of a bearded patient with the commonly used face mask has low efficiency because of difficulties to achieve a tight seal around the mouth and nose.
- Trial name
- BVGA02 (NCT04376918)
- Testing
- Begin with BVGA, Begin with Face-mask
- Where
- Israel
- Volunteers
- 101 people
- Sponsor
- Hebrew University of Jerusalem
Emergencies
Study to Evaluate Satisfaction Using Personal Health Wallet Service
The investigators developed the service showing patient health record altogether which is managed by each hospital separately and recording the patient health information based on mobile application.
- Trial name
- NCT04180618
- Testing
- Personal health wallet service for emergency situation
- Where
- South Korea
- Volunteers
- 1,010 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Circulatory Failure, Echocardiography
Diagnostic Performance of Echocardiography Performed by Emergency Physicians After a Basic Training
After a basic training to echocardiography, emergency physicians will have to answer simple clinical questions about circulatory failure mechanisms.
- Trial name
- ECHOBEDSIDE (NCT02974790)
- Testing
- Echocardiography
- Where
- France
- Volunteers
- 89 people
- Sponsor
- University Hospital, Limoges
Pulmonary Embolism
Pulmonary Embolism Diagnosis: Ultrasound Wells Score vs Traditional Wells Score
Pulmonary embolism (PE) should be suspected in patients with dyspnea, chest pain, syncope, shock/hypotension, or cardiac arrest.
- Trial name
- NCT02190110
- Where
- 4 sites in Italy
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Moderate-to-severe Acute Pain
Open-Label Safety and Efficacy of the Sufentanil Sublingual Tablet 30 mcg for Acute Pain
To evaluate the safety and efficacy of sufentanil tablet (ST) 30 mcg in the management of moderate-to-severe acute pain in patients in an emergency room (ER) setting.
- Trial name
- NCT02447848
- Testing
- sufentanil sublingual 30 mcg tablet
- Where
- 3 sites in United States
- Volunteers
- 76 people
- Sponsor
- Talphera, Inc
Hypertensive Urgency
Effect of Pursed-Lip Breathing on Blood Pressure and Heart Rate
Hypertensive urgency (HT urgency) is an alarm sign of uncontrolled hypertension. It can be aggravated by nonadherent to medication and psychosocial stress.
- Trial name
- NCT04572672
- Testing
- Non-pharmacologic treatment; Pursed-Lip Breathing Combined with Number Counting
- Where
- Thailand
- Volunteers
- 112 people
- Sponsor
- Khon Kaen University
Unexpected Infant Death, Prevention & Control
Impact of Prevention of Safe Sleeping and Unexpected Infant Death
The sudden unexpected infant death (SUID) is defined as "the sudden death of a child aged from 1 month to 1 year who had been healthy until then, whereas nothing in his known history or in the history of events could have allowed…
- Conditions
- Unexpected Infant Death, Prevention & Control, Safe Sleeping
- Trial name
- MinUTE (NCT07237360)
- Testing
- Sleeping mode
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Health Care Utilization, Health Care Seeking Behavior
Connecting Low-Income Adults to Primary Care After Inpatient Discharge
Healthcare systems and insurers have tried to reduce costs by improving the care and coordination provided to patients with high healthcare spending.
- Trial name
- NCT05567224
- Testing
- Access to primary care services
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Vanderbilt University Medical Center
Respiratory Infection
Unclogging the Pediatric Emergency Room: Impact of Rapid Viral Diagnostics
Acute respiratory tract infections are among the most common problems of childhood, particularly among infants and children younger than 3 years, and account for most antibiotic prescriptions to children.
- Trial name
- NCT00278759
- Testing
- Nasopharyngeal washing for viral antigen detection by immunofluorescence initiated early in ED visit.
- Where
- Canada
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Non Invasive Ventilation, Acute Respiratory Failure
Prevalence of an Early Success of Non-invasive Ventilation in the Emergency Departement.
Non-invasive ventilation is a mechanical ventilation who provides ventilatory support through a facemask, and without the need for tracheal intubation.
- Trial name
- VENTIRU (NCT06213623)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Poitiers University Hospital
Contraception
Providing Adolescent Contraception in the Emergency Room
The purpose of this pilot study is to determine the feasibility of comprehensive contraceptive counseling intervention in a pediatric emergency department and to determine the impact of comprehensive contraception counseling on…
- Trial name
- PACER (NCT02475980)
- Testing
- Comprehensive contraception counseling
- Volunteers
- 13 people
- Sponsor
- University of New Mexico
Acute Cholecystitis, Acute Cholecystitis With Obstruction
Patient Satisfaction After Ambulatory Emergency Laparoscopic Cholecystectomy
Acute cholecystitis is a common surgical emergency that, if left untreated, can result in significant morbidity and even death. It is characterized by inflammation of the gallbladder, usually caused by gallstones.
- Trial name
- NCT07616713
- Testing
- Laparoscopic Cholecystectomy
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Hospital General de Chihuahua - Dr. Salvador Zubirán Anchondo
Children with Medical Complexity, Child, Only
Emergency Care Action Plans for Infants with Medical Complexity
An Emergency Care Action Plan (ECAP) is a tool intended to be helpful to providers when treating a child with complex medical needs during an emergency.
- Conditions
- Children with Medical Complexity, Child, Only, Infant Morbidity, Infant Conditions
- Trial name
- ECAP (NCT06444282)
- Testing
- Emergency Care Action Plan
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Vermont