Clinical trials: Emergency Department Presentation
Dyspnea
Diagnostic Performance of Chest Computed Tomography Scan in Patients Aged 65 and Over Presenting to Emergency Room With Acute Dyspnea
In acute dyspnea, the use of chest radiography is frequent and not very contributive, especially in the elderly patients. However, early diagnosis of the cause of dyspnea in the ED is associated with a better prognosis, in…
- Trial name
- CT-Dys (NCT06104475)
- Testing
- CT scan
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Deficiency; Diet, Pregnancy
Prevalence and Risk Factors for Micronutrient Deficiencies During Pregnancy in Cayenne, French Guiana
Micronutrient deficiencies are frequent in pregnant women in French Guiana, a French territory in South America. Micronutrient deficiencies are more frequent in precarious women.
- Trial name
- CarMa (NCT05022979)
- Testing
- Observational only
- Where
- French Guiana
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
Ankle Sprain
Topical Ketoprofen Versus Placebo in Patients With Ankle Sprain
The aim of this study is to analyse the effect of ketoprofen gel in patients presented with ankle sprain to the emergency department.
- Trial name
- NCT02393846
- Testing
- Ketoprofen gel
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Akdeniz University
Bronchiolitis
Finding Better Treatment of Bronchiolitis: A Clinical Trial of Oral Nitazoxanide for the Treatment of Bronchiolitis in Infants Presenting to Hospital Emergency Departments
Bronchiolitis is an extremely common cause of respiratory illness in infants caused by viral infection.This study evaluates whether treatment with nitazoxanide (NTZ) reduces the duration and severity of respiratory symptoms…
- Trial name
- NCT02452905
- Testing
- Nitazoxanide
- Where
- Australia
- Sponsor
- Telethon Kids Institute
Migraine Disorders, Headache
The Effect of Intravenous Fluid Therapy in Acute Migraine Attacks
The study is a single-center, double-blind, randomized protocol comparison. The study will be conducted in Marmara University School of Medicine Pendik Training and Research Hospital, Department of Emergency Medicine between…
- Conditions
- Migraine Disorders, Headache, Acute Pain
- Trial name
- NCT04287140
- Testing
- Bolus fluid administration
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Upper Digestive Bleeding, Cirrhosis
Efficacity and Safety of Tranexamic Acid in Cirrhotic Patients Presenting With Acute Upper Gastrointestinal Bleeding
Upper digestive bleeding. Upper gastrointestinal haemorrhage is a common cause of decompensated cirrhosis and is associated with a high mortality rate among cirrhotic patients.
- Trial name
- EXARHOSE (NCT03023189)
- Testing
- Tranexamic acid
- Where
- 3 sites in France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Vaso-Occlusive Pain Episode in Sickle Cell Disease, Sickle Cell Disease (SCD)
Low Dose Bolus Ketamine For Use In Sickle Cell Pain Crisis
The goal of this study is to learn if Ketamine works more efficiently, as compared to Opioids, for Sickle Cell Pain The main questions it aims to answer are: Does Ketamine lower the number of times participants need to be…
- Trial name
- NCT07682662
- Testing
- Standardized Low-dose bolus IV Ketamine within 30 minutes of arrival and every 1 hour as needed for max of 3 doses., Standard Care (in control arm)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Mississippi Medical Center
Acute Pain
Safety of Hydromorphone in Adult Patients Presenting to the Emergency Department With Acute Severe Pain
The purpose of this study is to determine the safety and speed of onset of 2mg intravenous hydromorphone (Dilaudid) in patients weighing at least 150 lbs presenting to the emergency department with acute severe pain
- Trial name
- NCT00305110
- Testing
- 2 mg IV hydromorphone
- Where
- United States
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Asthma Acute
Retrospective Study of Patients with Acute Presentation for Asthma to an Emergency Department in UK (RAPAE)
Study team will obtain a list of all patients who have been seen in A+E over the past 6 years with a discharge diagnosis of asthma. Their history will be reviewed from their A+E notes.
- Trial name
- RAPAE (NCT06360185)
- Volunteers
- 400 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Low Back Pain, Back Pain
Feasibility of Telehealth Mindfulness for Back Pain in the Emergency Department
While guideline-directed nonpharmacological strategies for chronic low back pain are well established, optimal chronic pain management for emergency department patients has yet to be defined.
- Conditions
- Low Back Pain, Back Pain, Pain, Chronic Low-back Pain
- Trial name
- NCT04783532
- Testing
- Telehealth Mindfulness Program
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Vanderbilt University Medical Center
Syncope
Comparison Between Standard and Ultrasound Integrated Approach for Risk Stratification of Syncope in the Emergency Department
This is a observational prospective study. For patients presenting to the Emergency Department with loss of consciousness, emergency physicians will be asked to screen the real syncope without an evident and immediate cause for…
- Trial name
- NCT02781207
- Where
- Italy
- Volunteers
- 196 people
- Sponsor
- University of Turin, Italy
Stroke, Ischemic, Transient Ischemic Attack
TIA Scores' Mortality Predictions and Recurrent TIA and Stroke Prediction
Our study adopts a prospective design. Our research aims to determine the significance of ABCD2, ABCD3-I, Canadian TIA Score, and NIHSS Score in predicting the likelihood of ischemic stroke within 30 days in patients presenting…
- Trial name
- NCT06515392
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Saglik Bilimleri Universitesi
Acute Coronary Syndrome
Early Risk Stratification in ED Chest Pain Patients
In the management of adult chest pain patients presenting to an Emergency Department (ED) with suspected acute coronary syndrome (ACS), we aimed to evaluate the diagnostic accuracy of the combined use of a modified Thrombolysis…
- Trial name
- NCT02364271
- Testing
- Thrombolysis in myocardial infarction score, routine blood test for hs-cTnT, HEART score
- Where
- China
- Volunteers
- 602 people
- Sponsor
- Chinese University of Hong Kong
All Emergency Department Visits Meeting Eligibility Criteria
Prospective Evaluation of AI Generated History of Present Illness Drafts in the Emergency Department
This single-center prospective observational study evaluates whether an on-premise, large language model-based tool (EDnote) that generates a draft history of present illness (HPI) from real-time transcription of the…
- Trial name
- NCT07804407
- Testing
- EDnote HPI (AI-generated HPI draft), Conventional physician HPI
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Syncope, Vasovagal, Postural Orthostatic Tachycardia Syndrome
Paediatric Syncope in the Emergency Department
The investigators will assess the efficacy of clinically recommended counterpressure maneuvers (CPM) in preventing syncope for paediatric patients.
- Conditions
- Syncope, Vasovagal, Postural Orthostatic Tachycardia Syndrome, Orthostatic Intolerance
- Trial name
- DETECT-ED (NCT05555771)
- Testing
- Counterpressure Maneuvers, Usual Care
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Dr. Victoria Claydon
Renal Colic, Kidney Stones, Urolithiasis, Hypocitraturia
The Use of AR / VR in Patients Presenting to the ED With Renal Colic
Utilization of VR / AR Calming as an adjunct to pharmacologic pain management for Renal Colic in Emergency Department Patients
- Trial name
- NCT07070401
- Testing
- Commercial AR/VR Headset with Calming App, Pharmacologic Standard of Care Alone
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Community Medical Center, Toms River, NJ
Renal Colic
Comparing the Analgesic Effect of Intravenous Acetaminophen and Morphine on Patients With Renal Colic Pain Reffering to the Emergency Department: A Randomized Controlled Trial
Kidney stone is one of the most common diseases in every human society and also Iran. What is normally used to treat renal colic pain is Intravenous Opioid with a variety of side effects including hypotension, respiratory…
- Trial name
- NCT01906762
- Testing
- Acetaminophen, Morphine
- Volunteers
- 124 people
- Sponsor
- Seyed Mehdi Pourafzali
Heart Failure
Phase IIb Safety and Efficacy Study of BAY94-8862 in Subjects With Worsening Chronic Heart Failure and Left Ventricular Systolic Dysfunction and Either Type 2 Diabetes Mellitus With or Without Chronic Kidney Disease or Moderate Chronic Kidney Disease Alone
This study will be conducted in subjects with clinical diagnosis of worsening chronic heart failure and either type 2 diabetes mellitus (DM) with or without chronic kidney disease (CKD) or moderate CKD alone treated with…
- Trial name
- ARTS-HF Japan (NCT01955694)
- Testing
- BAY94-8862, Eplerenone
- Where
- 29 sites in Japan
- Volunteers
- 72 people
- Sponsor
- Bayer
Sepsis, Systemic Inflammatory Response Syndrome
Clinical Microbial Species & Antibiotic Resistance ID in ED Patients Presenting With Infection - is Rapid ID Possible & Accurate?
The aim of this project is to test the utility of The Gene Z device (as of 2018 Gene Z no longer being used), now using In-Dx and other rapid identification techniques that the investigators have developed in the lab on…
- Conditions
- Sepsis, Systemic Inflammatory Response Syndrome, Infection Mixed, Infection, Bacterial
- Trial name
- NCT01904188
- Testing
- Gene Z or other rapid diagnostic techniques developed in our lab (as of 2018 not using Gene Z - now using In-Dx along with other developed techniquesregularly)
- Where
- 2 sites in United States
- Volunteers
- 2,500 people
- Sponsor
- Michigan State University
Suicide, Suicide, Attempted
Focused Suicide Prevention Strategy for Youth
This study evaluates whether a Family-centered suicide prevention strategy, when added to usual care (F-SPS + UC), is more effective than enhanced usual care (EUC) in reducing suicide-related behaviors in 128 youth at high-risk…
- Conditions
- Suicide, Suicide, Attempted, Suicidal Ideation
- Trial name
- FSPS (NCT03488602)
- Testing
- F-SPS+UC, EUC
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- The Hospital for Sick Children