Clinical trials: Emergency Department Presentation
Anemia, Iron Deficiency, Uterine Bleeding
IV Iron Trial for Anemia Related to Uterine Bleeding in Female Patients Presenting to the Emergency Department
The primary aim of this randomized trial is to assess the efficacy of IV Ferric Derisomaltose vs Oral Iron in the management of women with severe Iron Deficiency Anemia due to Uterine Bleeding in the emergency department.
- Trial name
- NCT05304442
- Testing
- Ferric Derisomaltose 1000 Mg in 10 mL INTRAVENOUS SOLUTION [Monoferric], Ferrous Sulfate 65 mg elemental iron (325 mg tablets)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Acute Heart Failure (AHF)
Evaluation of Fibroscan® Performance in Diagnosing Acute Heart Failure in Patients Presenting to the Emergency Department
Acute heart failure (AHF) is a major cause of acute dyspnea in emergency departments (EDs), driven primarily by venous congestion, which can lead to hepatic congestion and risk of subsequent liver dysfunction.
- Trial name
- FIBROSCAF (NCT07449377)
- Testing
- FibroScan®
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lower Back Pain
Effect of Physiotherapy in Patients Presenting to the Emergency Department With Nonspecific Lower Back Pain
Physiotherapy is a long established therapy in lower back pain. It is unknown if physiotherapeutic interventions in patients presenting to the Emergency Department (ED) with nonspecific lower back pain are beneficial.
- Trial name
- EPAC-II (NCT05156957)
- Testing
- physiotherapeutic intervention
- Where
- Switzerland
- Volunteers
- 126 people
- Sponsor
- University Hospital, Basel, Switzerland
Gastro Intestinal Bleeding
The Value of End-tidal Capnography in Gastrointestinal Bleeding
Gastrointestinal bleeding is a condition that frequently presents to emergency departments and can be fatal if diagnosis and treatment are delayed.
- Trial name
- NCT06345456
- Testing
- End-tidal capnography
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Izmir Katip Celebi University
Myocardial Infarction, Angina, Unstable
Novel Method to Diagnose Acute Myocardial Ischemia
The aim of this study is to improve the detection of heart attack in people who come to a hospital emergency room (ER) with cardiac symptoms.
- Conditions
- Myocardial Infarction, Angina, Unstable, Myocardial Ischemia, Coronary Disease
- Trial name
- NCT00285922
- Where
- United States
- Volunteers
- 1,320 people
- Sponsor
- University of California, San Francisco
Delphi Process, Psychiatric Emergency
Protocol of an International Delphi Process
The aim of this study is to develop a consensus-based protocol for medical screening in patients presenting with acute psychiatric symptoms.
- Conditions
- Delphi Process, Psychiatric Emergency, Medical Screening
- Trial name
- NCT06936826
- Testing
- Delphi Consensus Process
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- University Hospital, Basel, Switzerland
Acute Chest Pain
Coronary CT Angiography in Acute Chest Pain is a Cost Effective Risk Stratification Strategy
This study will evaluate the impact of adding coronary computed tomographic angiography (CTA) on health care costs for diagnosing patients with acute chest pain.
- Trial name
- NCT00825435
- Testing
- Coronary CT Angiogram
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Asthma
Clinical, Airway Inflammatory, and HRA Phenotypes, in Preschool Children With Acute Asthmatic Attack Presenting to the ED.
Clinical, Airway Inflammatory, and HRA Phenotypes, in preschool children with acute asthmatic attack presenting to the ED. Background: Children under the age of 5 years have the highest hospitalization rate of asthma.
- Trial name
- NCT01175174
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Wolfson Medical Center
Appendicitis, Abdominal Pain
The Value of Pancreatic Stone Protein in Predicting Acute Appendicitis
PSP (Pancreatic Stone Protein) is a compound naturally produced mainly in the pancreas and the gut. There is evidence from experimental and clinical trials that the levels of PSP in the blood rise in the presence of inflammation…
- Conditions
- Appendicitis, Abdominal Pain, Abdominal Sepsis
- Trial name
- NCT01610193
- Testing
- Appendicectomy
- Where
- 2 sites in Switzerland
- Volunteers
- 245 people
- Sponsor
- University of Zurich
Heart Failure, Dyspnea
NT-proBNP in Acute Dyspnea: Effects on Treatment, Hospitalisation and Costs
Diagnostic uncertainty in patients with complaints of shortness of breath presenting to the Emergency Department of a hospital may delay treatment and proper care.
- Trial name
- NCT00410293
- Testing
- NT-proBNP testing
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Erasmus Medical Center
Sepsis
Non-invasive Measurement of CO in Patients With Uncomplicated Sepsis
Little is known about the optimal fluid therapy of patients with uncomplicated sepsis. Most recommendations are extrapolated from studies performed in patients with septic shock.
- Trial name
- NCT03728998
- Testing
- Passive leg raise (PLR), Clearsight non-invasive hemodynamic monitoring system
- Where
- Netherlands
- Volunteers
- 31 people
- Sponsor
- Frisius Medisch Centrum
Acute Coronary Syndrome (ACS)
Optimum Troponin Cutoffs for ACS in the ED
Blood tests may be able to quickly identify and exclude patients that are having a heart attack. Using these tests in the Emergency Department (ED) may lead to faster treatment, a reduced wait time, and quicker discharge for…
- Trial name
- ROMI-3 (NCT01994577)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Canadian Institutes of Health Research (CIHR)
Suicide, Suicidal
Safe Treatment for Emergency Presentation for Suicidal Ideation and Behavior in Youth
This randomized comparative effectiveness trial will compare two evidence-based approaches to emergency care for youth ages 13-24 who present to the Emergency Department (ED) with suicidal ideation or behavior.
- Conditions
- Suicide, Suicidal, Self-Harm
- Trial name
- SAFE STEPS (NCT05304065)
- Testing
- SAFETY-A within usual ED Care, Combined SAFETY-A within usual ED Care + CLASP Therapeutic Follow-Up Contacts
- Where
- 5 sites in United States
- Volunteers
- 1,600 people
- Sponsor
- University of California, Los Angeles
Psychiatric Issue
Self Reported Level of Agitation of Patients Presenting to an Emergency Department
In recent years, there has been an emphasis on assessing patient's pain on presentation to emergency departments. The Joint Commission mandates that all patients who present with pain must have a pain assessment performed and…
- Trial name
- NCT02713100
- Testing
- level of agitation
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Leslie Zun, MD
Hypertension, Adolescent Behavior
Youth-Led Intervention to Improve Blood Pressure
The proposed study will develop, test, and collect implementation data on a youth-led hypertension (HTN) education intervention, which will act as an electronic tool to guide youth through learning and then teaching adults on how…
- Conditions
- Hypertension, Adolescent Behavior, Health Knowledge, Attitudes, Practice
- Trial name
- NCT05029687
- Testing
- Youth-Led Hypertension Education Digital Intervention
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Chest Pain, Acute Coronary Syndrome
Coronary Computed Tomographic Angiography in Intermediate-risk Chest Pain Patients
The aim is to determine whether a diagnostic strategy including early coronary computed tomographic angiography in intermediate-risk patients presenting to the Emergency Department with chest pain reduces the composite endpoint…
- Conditions
- Chest Pain, Acute Coronary Syndrome, Coronary Artery Disease
- Trial name
- FAST-CCTA (NCT04748237)
- Testing
- Coronary computed tomopraphic angiography
- Where
- Sweden
- Volunteers
- 1,600 people
- Sponsor
- Karolinska Institutet
Fractures, Dislocations
Diagnosing Extremity Fractures and/or Dislocations Using Ultrasound Presenting to the Emergency Department
The purpose of this study is to determine the efficacy of ultrasound in diagnosing the presence or absence of extremity fractures or dislocations.
- Trial name
- NCT00356837
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 323 people
- Sponsor
- United States Army Institute of Surgical Research
Mild Traumatic Brain Injury, Concussion, Mild
Facilitating Access to Specialty Treatment
The goal of this hybrid implementation-effectiveness study is to evaluate the effectiveness (hastened recovery times) and feasibility (fidelity in connecting to concussion specialty care) of a novel mobile health intervention…
- Conditions
- Mild Traumatic Brain Injury, Concussion, Mild, Concussion, Severe, Concussion, Intermediate
- Trial name
- NCT05741411
- Testing
- RPM-assisted specialist access
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Children's Hospital of Philadelphia
Acute Coronary Syndrome
VitalScan MCG Rule-out Multi-centre Pivotal Study - UK
The study is a prospective multi-centre observational study to evaluate a portable magnetocardiograph device for the rule-out of acute coronary syndrome (ACS) in patients who present to the emergency department with chest pain…
- Trial name
- MAGNET-ACS (NCT02921438)
- Testing
- VitalScan Magnetocardiograph
- Where
- 5 sites in United Kingdom
- Volunteers
- 756 people
- Sponsor
- Creavo Medical Technologies Ltd
Migraine
Oral Dexamethasone for the Treatment of Acute Migraine Recurrence in the Pediatric Emergency Department
Migraine recurrence is common amongst pediatric patients being discharged from the emergency department after treatment for migraine.
- Trial name
- NCT02794441
- Testing
- Dexamethasone
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Children's Hospital of Eastern Ontario